Synthesis of biocompatible PEG-based star polymers with cationic and degradable core for siRNA delivery

Biomacromolecules

Volumn 12, Issue 10, 2011, Pages 3478-3486

  Cho, Hong Y ^a   Srinivasan, Abiraman ^a   Hong, Joanna ^a   Hsu, Eric ^a   Liu, Shiguang ^a   Shrivats, Arun ^a   Kwak, Dan ^a   Bohaty, Andrew K ^a   Paik, Hyun Jong ^b   Hollinger, Jeffrey O ^a   Matyjaszewski, Krzysztof ^a  

^a CARNEGIE MELLON UNIVERSITY   (United States)

^b Pusan National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

2-(DIMETHYLAMINO)ETHYL METHACRYLATE; ATOM TRANSFER RADICAL COPOLYMERIZATION; CELL VIABILITY; CELLULAR UPTAKE; CROSSLINKER; DIMETHACRYLATES; GLUTATHIONES; HIGH CONCENTRATION; MACROMONOMER; POLY(ETHYLENE GLYCOL) METHYL ETHER METHACRYLATE (PEG-MMA); POLYMERIC CHAIN; POTENTIAL VALUES; REDOX CONDITION; SIRNA DELIVERY; STAR POLYMERS;

ACRYLIC MONOMERS; BIOCOMPATIBILITY; CONFOCAL MICROSCOPY; ETHERS; ETHYLENE; FLOW CYTOMETRY; FREE RADICAL REACTIONS; GLYCOLS; MAMMALS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; STARS; ZETA POTENTIAL;

POLYMERS;

CATION; DISULFIDE; DISULFIDE DIMETHACRYLATE; GLUTATHIONE; MACROGOL; METHACRYLIC ACID DIMETHYLAMINOETHYL ESTER; POLY(ETHYLENE GLYCOL)METHYL ETHER METHACRYLATE MACROMONOMER; POLYMER; SMALL INTERFERING RNA; STAR POLYMER; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ATOM TRANSFER RADICAL COPOLYMERIZATION; BIOCOMPATIBILITY; BIODEGRADATION; CALVARIA; CELL PROLIFERATION; CELL VIABILITY; COMPLEX FORMATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CROSS LINKING; EMBRYO; FLOW CYTOMETRY; GENE TARGETING; INTERNALIZATION; LIGHT SCATTERING; MOUSE; NONHUMAN; OSTEOBLAST; POLYMERIZATION; PRIORITY JOURNAL; RNA CLEAVAGE; SYNTHESIS; ZETA POTENTIAL;

ANIMALS; BIOCOMPATIBLE MATERIALS; CATIONS; CELL LINE; CELL SURVIVAL; CROSS-LINKING REAGENTS; DRUG CARRIERS; ENDOCYTOSIS; FLOW CYTOMETRY; GLUTATHIONE; LIGHT; METHACRYLATES; MICE; OSTEOBLASTS; PARTICLE SIZE; POLYETHYLENE GLYCOLS; RNA, SMALL INTERFERING; SCATTERING, RADIATION;

EID: 80053994498     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm2006455     Document Type: Article

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