Facile synthesis of multivalent folate-block copolymer conjugates via aqueous RAFT polymerization: Targeted delivery of siRNA and subsequent gene suppression

Biomacromolecules

Volumn 10, Issue 4, 2009, Pages 936-943

  York, Adam W ^a   Zhang, Yilin ^b   Holley, Andrew C ^a   Guo, Yanlin ^c   Huang, Faqing ^b   McCormick, Charles L ^a,b  

^a Virginia Polytechnic Institute and State University   (United States)

^b UNIVERSITY OF SOUTHERN MISSISSIPPI   (United States)

^c The University of Southern Mississippi   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE FUNCTIONALITIES; AMINOPROPYL; AQUEOUS SOLUTIONS; CANCER CELLS; CATIONIC COPOLYMERS; CHARGED COMPLEXES; CONJUGATED BLOCK COPOLYMERS; DOWN REGULATIONS; ELECTROSTATIC COMPLEXATION; FACILE SYNTHESIS; FOLATE RECEPTORS; GENE SUPPRESSIONS; HYDROPHILIC MONOMERS; METHACRYLAMIDE; NEUTRAL COMPLEXES; PHOSPHATE BACKBONES; PRIMARY AMINES; RAFT POLYMERIZATIONS; REVERSIBLE ADDITION-FRAGMENTATION CHAIN TRANSFER POLYMERIZATIONS; RIBONUCLEIC ACIDS; TARGETED DELIVERIES;

AMINES; BIOCOMPATIBILITY; BLOCK COPOLYMERS; CATIONIC POLYMERIZATION; COPOLYMERIZATION; DYES; FLUORESCENCE MICROSCOPY; FUNCTIONAL POLYMERS; HYDROPHILICITY; LIVING POLYMERIZATION; MONOMERS; NUCLEIC ACIDS; ORGANIC POLYMERS; RNA; SYNTHESIS (CHEMICAL);

POLYMERS;

ACRYLAMIDE DERIVATIVE; AMINE; CATION; COPOLYMER; FOLATE RECEPTOR; FOLIC ACID; FOLIC ACID DERIVATIVE; MONOMER; N (2 HYDROXYPROPYL)METHACRYLAMIDE; SMALL INTERFERING RNA; CARRIER PROTEIN; CELL SURFACE RECEPTOR; N-(2-HYDROXYPROPYL)METHACRYLAMIDE; POLYMER;

BIOCOMPATIBILITY; CANCER CELL; CHEMICAL STRUCTURE; COMPLEX FORMATION; CONFERENCE PAPER; CONJUGATE; CONJUGATION; CONTROLLED STUDY; DOWN REGULATION; DRUG SYNTHESIS; FLUORESCENCE MICROSCOPY; FRAGMENTATION REACTION; GENE OVEREXPRESSION; GENE REPRESSION; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NONVIRAL GENE DELIVERY SYSTEM; POLYMERIZATION; PRIORITY JOURNAL; ADENOCARCINOMA; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG DELIVERY SYSTEM; GENETICS; KB CELL LINE; LUNG TUMOR; METABOLISM; SYNTHESIS; TUMOR CELL CULTURE;

ACRYLAMIDES; ADENOCARCINOMA; CARRIER PROTEINS; CATIONS; DRUG DELIVERY SYSTEMS; FOLIC ACID; HUMANS; KB CELLS; LUNG NEOPLASMS; POLYMERS; RECEPTORS, CELL SURFACE; RNA, SMALL INTERFERING; TUMOR CELLS, CULTURED; FOLATE RECEPTORS, GPI-ANCHORED;

EID: 65249138811     PISSN: 15257797     EISSN: None     Source Type: Journal    
DOI: 10.1021/bm8014768     Document Type: Conference Paper

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