Tailoring the efficacy of nimodipine drug delivery using nanocarriers based on A2B miktoarm star polymers

Biomaterials

Volumn 31, Issue 32, 2010, Pages 8382-8392

  Soliman, Ghareb M ^a   Sharma, Rishi ^a   Choi, Angela O ^a   Varshney, Sunil K ^b   Winnik, Françoise M ^c   Kakkar, Ashok K ^a   Maysinger, Dusica ^a  

^a MCGILL UNIVERSITY   (Canada)

^b INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Drug delivery; Micelle; Microglia; Miktoarm; Neuroinflammation; Nimodipine

Indexed keywords

AQUEOUS SOLUBILITY; COSOLVENTS; CYTOKINES; ENCAPSULATION EFFICIENCY; HYDROPHOBIC DRUG; IN-VITRO; LIPOPOLYSACCHARIDES; LOADING EFFICIENCY; MICROGLIA; MIKTOARM; MIKTOARM STAR POLYMERS; NANOCARRIERS; NEUROINFLAMMATION; NEUROLOGICAL DISORDERS; NIMODIPINE; POLYETHYLENE GLYCOLS (PEG); SPHERICAL MICELLES; STAR POLYMERS; WEIGHT RATIOS;

CARBOXYLIC ACIDS; DRUG DELIVERY; ENCAPSULATION; ENZYME INHIBITION; FUNCTIONAL POLYMERS; MICELLES; NITRIC OXIDE; POLYCAPROLACTONE; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; PYRIDINE; RING OPENING POLYMERIZATION; SOLUBILITY;

POLYMERS;

3,5 BIS(PROP 2 YNYLOXY)PHENYL METHANOL; LIPOPOLYSACCHARIDE; MACROGOL; NANOCARRIER; NIMODIPINE; NITRIC OXIDE; POLYCAPROLACTONE; POLYMER; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; BRAIN ISCHEMIA; CELL ENCAPSULATION; CELL VIABILITY; CONCENTRATION PROCESS; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; ENCAPSULATION; EVAPORATION; FREEZE DRYING; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; MICELLE; MICROGLIA; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RING OPENING METATHESIS POLYMERIZATION; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CALCIUM CHANNEL BLOCKERS; CELL LINE; CELL SURVIVAL; CYTOKINES; DRUG CARRIERS; INFLAMMATION; MICE; MICELLES; MICROGLIA; NIMODIPINE; NITRIC OXIDE; POLYESTERS; POLYETHYLENE GLYCOLS;

EID: 77956182736     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.07.039     Document Type: Article

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