CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models

Gut

Volumn 58, Issue 10, 2009, Pages 1391-1398

  Schneiderhan, W ^a   Scheler, M ^b   Holzmann, K H ^b   Marx, M ^b   Gschwend, J E ^c   Bucholz, M ^d   Gress, T M ^d   Seufferlein, T ^e   Adler, G ^b   Oswald, F ^b  

^a UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^b UNIVERSITY HOSPITAL ULM   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d UNIVERSITY HOSPITAL MARBURG   (Germany)

^e MARTIN LUTHER UNIVERSITÄT HALLE WITTENBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD147 ANTIGEN; LACTIC ACID; MONOCARBOXYLATE TRANSPORTER 1; MONOCARBOXYLATE TRANSPORTER 4; SHORT HAIRPIN RNA; SODIUM AZIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CANCER INVASION; CANCER MODEL; CARCINOGENICITY; CELL PROLIFERATION; CHICK EMBRYO; CHORIOALLANTOIS; CONCENTRATION RESPONSE; EMBRYO; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOHISTOLOGY; MOUSE; NONHUMAN; NUDE MOUSE; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR XENOGRAFT;

ANIMALS; ANTIGENS, CD147; BLOTTING, WESTERN; CARCINOMA, PANCREATIC DUCTAL; CHICK EMBRYO; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE SILENCING; GLUCOSE; LACTIC ACID; MICE; MONOCARBOXYLIC ACID TRANSPORTERS; MUSCLE PROTEINS; NEOPLASM PROTEINS; PANCREATIC NEOPLASMS; RNA, SMALL INTERFERING; SYMPORTERS; UP-REGULATION;

EID: 70349307027     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gut.2009.181412     Document Type: Article

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