-
1
-
-
0842281645
-
Cell death: Critical control points
-
Danial NN, Korsmeyer SJ. Cell death: Critical control points. Cell 2004; 116: 205-19.
-
(2004)
Cell
, vol.116
, pp. 205-219
-
-
Danial, N.N.1
Korsmeyer, S.J.2
-
3
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr JF, Wyllie AH, Currie AR. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972; 26: 239-57.
-
(1972)
Br J Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
4
-
-
1342284231
-
Molecular mechanisms for cardiovascular stem cell apoptosis and growth in the hearts with atherosclerotic coronary disease and ischemic heart failure
-
Geng YJ. Molecular mechanisms for cardiovascular stem cell apoptosis and growth in the hearts with atherosclerotic coronary disease and ischemic heart failure. Ann N Y Acad Sci 2003; 1010: 687-97.
-
(2003)
Ann N Y Acad Sci
, vol.1010
, pp. 687-697
-
-
Geng, Y.J.1
-
5
-
-
3042839751
-
Targeting endogenous inhibitors of apoptosis for treatment of cancer, stroke and multiple sclerosis
-
Holcik M. Targeting endogenous inhibitors of apoptosis for treatment of cancer, stroke and multiple sclerosis. Expert Opin Ther Targets 2004; 8: 241-53.
-
(2004)
Expert Opin Ther Targets
, vol.8
, pp. 241-253
-
-
Holcik, M.1
-
6
-
-
0038205745
-
Targeting programmed cell death in neurodegenerative diseases
-
Vila M, Przedborski S. Targeting programmed cell death in neurodegenerative diseases. Nat Rev Neurosci 2003; 4: 365-75.
-
(2003)
Nat Rev Neurosci
, vol.4
, pp. 365-375
-
-
Vila, M.1
Przedborski, S.2
-
9
-
-
0033179760
-
BCL-2 family members and the mitochondria in apoptosis
-
Gross A, McDonnell JM, Korsmeyer SJ. BCL-2 family members and the mitochondria in apoptosis. Genes Dev 1999; 13: 1899-911.
-
(1999)
Genes Dev
, vol.13
, pp. 1899-1911
-
-
Gross, A.1
McDonnell, J.M.2
Korsmeyer, S.J.3
-
10
-
-
0032575714
-
Death receptors: Signaling and modulation
-
Ashkenazi A, Dixit VM. Death receptors: Signaling and modulation. Science 1998; 281: 1305-8.
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
11
-
-
8444220527
-
Molecular mechanisms of caspase regulation during apoptosis
-
Riedl SJ, Shi Y. Molecular mechanisms of caspase regulation during apoptosis. Nat Rev Mol Cell Biol 2004; 5: 897-907.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 897-907
-
-
Riedl, S.J.1
Shi, Y.2
-
12
-
-
0036022407
-
Initiator caspases in apoptosis signaling pathways
-
Chen M, Wang J. Initiator caspases in apoptosis signaling pathways. Apoptosis 2002; 7: 313-9.
-
(2002)
Apoptosis
, vol.7
, pp. 313-319
-
-
Chen, M.1
Wang, J.2
-
13
-
-
33845501864
-
A platform for the activation of initiator caspases
-
Bao Q, Shi Y. Apoptosome: A platform for the activation of initiator caspases. Cell Death Differ 2007; 14: 56-65.
-
(2007)
Cell Death Differ
, vol.14
, pp. 56-65
-
-
Bao, Q.1
Apoptosome Shi, Y.2
-
14
-
-
0037291871
-
A unified model for apical caspase activation
-
Boatright KM, Renatus M, Scott FL, Sperandio S, Shin H, Pedersen IM, et al. A unified model for apical caspase activation. Mol Cell 2003; 11: 529-41.
-
(2003)
Mol Cell
, vol.11
, pp. 529-541
-
-
Boatright, K.M.1
Renatus, M.2
Scott, F.L.3
Sperandio, S.4
Shin, H.5
Pedersen, I.M.6
-
15
-
-
0344142396
-
Emerging roles of caspase-3 in apoptosis
-
Porter AG, Janicke RU. Emerging roles of caspase-3 in apoptosis. Cell Death Differ 1999; 6: 99-104.
-
(1999)
Cell Death Differ
, vol.6
, pp. 99-104
-
-
Porter, A.G.1
Janicke, R.U.2
-
16
-
-
0032428841
-
Investigation of glucocorticoid-induced apoptotic pathway: Processing of caspase-6 but not caspase-3
-
Miyashita T, Nagao K, Krajewski S, Salvesen GS, Reed JC, Inoue T, et al. Investigation of glucocorticoid-induced apoptotic pathway: Processing of caspase-6 but not caspase-3. Cell Death Differ 1998; 5: 1034-41.
-
(1998)
Cell Death Differ
, vol.5
, pp. 1034-1041
-
-
Miyashita, T.1
Nagao, K.2
Krajewski, S.3
Salvesen, G.S.4
Reed, J.C.5
Inoue, T.6
-
17
-
-
0030970351
-
Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity
-
Zhou Q, Salvesen GS. Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity. Biochem J 1997; 324 (Pt 2): 361-4.
-
(1997)
Biochem J
, vol.324
, Issue.Pt 2
, pp. 361-364
-
-
Zhou, Q.1
Salvesen, G.S.2
-
18
-
-
0037427444
-
Mitochondrial intermembrane proteins in cell death
-
van Gurp M, Festjens N, van Loo G, Saelens X, Vandenabeele P. Mitochondrial intermembrane proteins in cell death. Biochem Biophys Res Commun 2003; 304: 487-97.
-
(2003)
Biochem Biophys Res Commun
, vol.304
, pp. 487-497
-
-
van Gurp, M.1
Festjens, N.2
van Loo, G.3
Saelens, X.4
Vandenabeele, P.5
-
19
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosisinducing factor
-
Susin SA, Lorenzo HK, Zamzami N, Marzo I, Snow BE, Brothers GM, et al. Molecular characterization of mitochondrial apoptosisinducing factor. Nature 1999; 397: 441-6.
-
(1999)
Nature
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
Marzo, I.4
Snow, B.E.5
Brothers, G.M.6
-
20
-
-
0035890085
-
The expanding role of mitochondria in apoptosis
-
Wang X. The expanding role of mitochondria in apoptosis. Genes Dev 2001; 15: 2922-33.
-
(2001)
Genes Dev
, vol.15
, pp. 2922-2933
-
-
Wang, X.1
-
21
-
-
0345276414
-
Bcl-2-family proteins and the role of mitochondria in apoptosis
-
Kuwana T, Newmeyer DD. Bcl-2-family proteins and the role of mitochondria in apoptosis. Curr Opin Cell Biol 2003; 15: 691-9.
-
(2003)
Curr Opin Cell Biol
, vol.15
, pp. 691-699
-
-
Kuwana, T.1
Newmeyer, D.D.2
-
22
-
-
37549048249
-
The BCL-2 protein family: Opposing activities that mediate cell death
-
Youle RJ, Strasser A. The BCL-2 protein family: Opposing activities that mediate cell death. Nat Rev Mol Cell Biol 2008; 9: 47-59.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
-
23
-
-
68249106060
-
BH3-only proteins in apoptosis and beyond: An overview
-
Lomonosova E, Chinnadurai G. BH3-only proteins in apoptosis and beyond: An overview. Oncogene 2008; 27 (Suppl 1): S2-19.
-
(2008)
Oncogene
, vol.27
, Issue.SUPPL. 1
, pp. 2-19
-
-
Lomonosova, E.1
Chinnadurai, G.2
-
24
-
-
34247345833
-
The apoptosome: Signalling platform of cell death
-
Riedl SJ, Salvesen GS. The apoptosome: Signalling platform of cell death. Nat Rev Mol Cell Biol 2007; 8: 405-13.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 405-413
-
-
Riedl, S.J.1
Salvesen, G.S.2
-
25
-
-
0037273848
-
Apo2L/TRAIL and its death and decoy receptors
-
LeBlanc HN, Ashkenazi A. Apo2L/TRAIL and its death and decoy receptors. Cell Death Differ 2003; 10: 66-75.
-
(2003)
Cell Death Differ
, vol.10
, pp. 66-75
-
-
Leblanc, H.N.1
Ashkenazi, A.2
-
26
-
-
17544367410
-
Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
-
Pitti RM, Marsters SA, Ruppert S, Donahue CJ, Moore A, Ashkenazi A. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J Biol Chem 1996; 271: 12687-90.
-
(1996)
J Biol Chem
, vol.271
, pp. 12687-90
-
-
Pitti, R.M.1
Marsters, S.A.2
Ruppert, S.3
Donahue, C.J.4
Moore, A.5
Ashkenazi, A.6
-
27
-
-
13344285339
-
Identification and characterization of a new member of the TNF family that induces apoptosis
-
Wiley SR, Schooley K, Smolak PJ, Din WS, Huang CP, Nicholl JK, et al. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 1995; 3: 673-82.
-
(1995)
Immunity
, vol.3
, pp. 673-682
-
-
Wiley, S.R.1
Schooley, K.2
Smolak, P.J.3
Din, W.S.4
Huang, C.P.5
Nicholl, J.K.6
-
28
-
-
0031719383
-
Involvement of APO2 ligand/TRAIL in activation-induced death of Jurkat and human peripheral blood T cells
-
Martinez-Lorenzo MJ, Alava MA, Gamen S, Kim KJ, Chuntharapai A, Pineiro A, et al. Involvement of APO2 ligand/TRAIL in activation-induced death of Jurkat and human peripheral blood T cells. Eur J Immunol 1998; 28: 2714-25.
-
(1998)
Eur J Immunol
, vol.28
, pp. 2714-2725
-
-
Martinez-Lorenzo, M.J.1
Alava, M.A.2
Gamen, S.3
Kim, K.J.4
Chuntharapai, A.5
Pineiro, A.6
-
29
-
-
0037338951
-
Defective thymocyte apoptosis and accelerated autoimmune diseases in TRAIL-/-mice
-
Lamhamedi-Cherradi SE, Zheng SJ, Maguschak KA, Peschon J, Chen YH. Defective thymocyte apoptosis and accelerated autoimmune diseases in TRAIL-/-mice. Nat Immunol 2003; 4: 255-60.
-
(2003)
Nat Immunol
, vol.4
, pp. 255-260
-
-
Lamhamedi-Cherradi, S.E.1
Zheng, S.J.2
Maguschak, K.A.3
Peschon, J.4
Chen, Y.H.5
-
31
-
-
35349022320
-
Apo2L/TRAIL and immune regulation
-
Anel A, Bosque A, Naval J, Pineiro A, Larrad L, Alava MA, et al. Apo2L/TRAIL and immune regulation. Front Biosci 2007; 12: 2074-84.
-
(2007)
Front Biosci
, vol.12
, pp. 2074-2084
-
-
Anel, A.1
Bosque, A.2
Naval, J.3
Pineiro, A.4
Larrad, L.5
Alava, M.A.6
-
32
-
-
0035137696
-
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells
-
Takeda K, Hayakawa Y, Smyth MJ, Kayagaki N, Yamaguchi N, Kakuta S, et al. Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells. Nat Med 2001; 7: 94-100.
-
(2001)
Nat Med
, vol.7
, pp. 94-100
-
-
Takeda, K.1
Hayakawa, Y.2
Smyth, M.J.3
Kayagaki, N.4
Yamaguchi, N.5
Kakuta, S.6
-
33
-
-
0034710821
-
Isolation and molecular characterization of the 5'-upstream region of the human TRAIL gene
-
Wang Q, Ji Y, Wang X, Evers BM. Isolation and molecular characterization of the 5'-upstream region of the human TRAIL gene. Biochem Biophys Res Commun 2000; 276: 466-71.
-
(2000)
Biochem Biophys Res Commun
, vol.276
, pp. 466-471
-
-
Wang, Q.1
Ji, Y.2
Wang, X.3
Evers, B.M.4
-
34
-
-
0034142219
-
A unique zinc-binding site revealed by a highresolution X-ray structure of homotrimeric Apo2L/TRAIL
-
Hymowitz SG, O'Connell MP, Ultsch MH, Hurst A, Totpal K, Ashkenazi A, et al. A unique zinc-binding site revealed by a highresolution X-ray structure of homotrimeric Apo2L/TRAIL. Biochemistry 2000; 39: 633-40.
-
(2000)
Biochemistry
, vol.39
, pp. 633-640
-
-
Hymowitz, S.G.1
O'Connell, M.P.2
Ultsch, M.H.3
Hurst, A.4
Totpal, K.5
Ashkenazi, A.6
-
35
-
-
0033212968
-
Triggering cell death: The crystal structure of Apo2L/TRAIL in a complex with death receptor 5
-
Hymowitz SG, Christinger HW, Fuh G, Ultsch M, O'Connell M, Kelley RF, et al. Triggering cell death: The crystal structure of Apo2L/TRAIL in a complex with death receptor 5. Mol Cell 1999; 4: 563-71.
-
(1999)
Mol Cell
, vol.4
, pp. 563-571
-
-
Hymowitz, S.G.1
Christinger, H.W.2
Fuh, G.3
Ultsch, M.4
O'Connell, M.5
Kelley, R.F.6
-
36
-
-
0033169230
-
2.8 A resolution crystal structure of human TRAIL, a cytokine with selective antitumor activity
-
Cha SS, Kim MS, Choi YH, Sung BJ, Shin NK, Shin HC, et al. 2.8 A resolution crystal structure of human TRAIL, a cytokine with selective antitumor activity. Immunity 1999; 11: 253-61.
-
(1999)
Immunity
, vol.11
, pp. 253-261
-
-
Cha, S.S.1
Kim, M.S.2
Choi, Y.H.3
Sung, B.J.4
Shin, N.K.5
Shin, H.C.6
-
37
-
-
0035050960
-
Differential hepatocyte toxicity of recombinant Apo2L/ TRAIL versions
-
Lawrence D, Shahrokh Z, Marsters S, Achilles K, Shih D, Mounho B, et al. Differential hepatocyte toxicity of recombinant Apo2L/ TRAIL versions. Nat Med 2001; 7: 383-5.
-
(2001)
Nat Med
, vol.7
, pp. 383-385
-
-
Lawrence, D.1
Shahrokh, Z.2
Marsters, S.3
Achilles, K.4
Shih, D.5
Mounho, B.6
-
38
-
-
0030996297
-
The receptor for the cytotoxic ligand TRAIL
-
Pan G, O'Rourke K, Chinnaiyan AM, Gentz R, Ebner R, Ni J, et al. The receptor for the cytotoxic ligand TRAIL. Science 1997; 276: 111-3.
-
(1997)
Science
, vol.276
, pp. 111-113
-
-
Pan, G.1
O'Rourke, K.2
Chinnaiyan, A.M.3
Gentz, R.4
Ebner, R.5
Ni, J.6
-
39
-
-
0031406386
-
Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway
-
Chaudhary PM, Eby M, Jasmin A, Bookwalter A, Murray J, Hood L. Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway. Immunity 1997; 7: 821-30.
-
(1997)
Immunity
, vol.7
, pp. 821-830
-
-
Chaudhary, P.M.1
Eby, M.2
Jasmin, A.3
Bookwalter, A.4
Murray, J.5
Hood, L.6
-
40
-
-
0033662433
-
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5
-
Kischkel FC, Lawrence DA, Chuntharapai A, Schow P, Kim KJ, Ashkenazi A. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. Immunity 2000; 12: 611-20.
-
(2000)
Immunity
, vol.12
, pp. 611-620
-
-
Kischkel, F.C.1
Lawrence, D.A.2
Chuntharapai, A.3
Schow, P.4
Kim, K.J.5
Ashkenazi, A.6
-
41
-
-
0032929520
-
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
-
Walczak H, Miller RE, Ariail K, Gliniak B, Griffith TS, Kubin M, et al. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med 1999; 5: 157-63.
-
(1999)
Nat Med
, vol.5
, pp. 157-163
-
-
Walczak, H.1
Miller, R.E.2
Ariail, K.3
Gliniak, B.4
Griffith, T.S.5
Kubin, M.6
-
42
-
-
0030792712
-
Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
-
Sheridan JP, Marsters SA, Pitti RM, Gurney A, Skubatch M, Baldwin D, et al. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science 1997; 277: 818-21.
-
(1997)
Science
, vol.277
, pp. 818-821
-
-
Sheridan, J.P.1
Marsters, S.A.2
Pitti, R.M.3
Gurney, A.4
Skubatch, M.5
Baldwin, D.6
-
43
-
-
0030762815
-
An antagonist decoy receptor and a death domain-containing receptor for TRAIL
-
Pan G, Ni J, Wei YF, Yu G, Gentz R, Dixit VM. An antagonist decoy receptor and a death domain-containing receptor for TRAIL. Science 1997; 277: 815-8.
-
(1997)
Science
, vol.277
, pp. 815-818
-
-
Pan, G.1
Ni, J.2
Wei, Y.F.3
Yu, G.4
Gentz, R.5
Dixit, V.M.6
-
44
-
-
29144496895
-
Preligand assembly domain-mediated ligandindependent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis
-
Clancy L, Mruk K, Archer K, Woelfel M, Mongkolsapaya J, Screaton G, et al. Preligand assembly domain-mediated ligandindependent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis. Proc Natl Acad Sci USA 2005; 102: 18099-104.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 18099-104
-
-
Clancy, L.1
Mruk, K.2
Archer, K.3
Woelfel, M.4
Mongkolsapaya, J.5
Screaton, G.6
-
45
-
-
33749164762
-
Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2
-
Merino D, Lalaoui N, Morizot A, Schneider P, Solary E, Micheau O. Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2. Mol Cell Biol 2006; 26: 7046-55.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 7046-7055
-
-
Merino, D.1
Lalaoui, N.2
Morizot, A.3
Schneider, P.4
Solary, E.5
Micheau, O.6
-
46
-
-
12544255082
-
Receptor-selective mutants of apoptosis-inducing ligand 2/tumor necrosis factor-related apoptosis-inducing ligand reveal a greater contribution of death receptor (DR) 5 than DR4 to apoptosis signaling
-
Kelley RF, Totpal K, Lindstrom SH, Mathieu M, Billeci K, Deforge L, et al. Receptor-selective mutants of apoptosis-inducing ligand 2/tumor necrosis factor-related apoptosis-inducing ligand reveal a greater contribution of death receptor (DR) 5 than DR4 to apoptosis signaling. J Biol Chem 2005; 280: 2205-12.
-
(2005)
J Biol Chem
, vol.280
, pp. 2205-2212
-
-
Kelley, R.F.1
Totpal, K.2
Lindstrom, S.H.3
Mathieu, M.4
Billeci, K.5
Deforge, L.6
-
47
-
-
34250029013
-
Membrane expression of DR4, DR5 and caspase-8 levels, but not Mcl-1, determine sensitivity of human myeloma cells to Apo2L/TRAIL
-
Gomez-Benito M, Martinez-Lorenzo MJ, Anel A, Marzo I, Naval J. Membrane expression of DR4, DR5 and caspase-8 levels, but not Mcl-1, determine sensitivity of human myeloma cells to Apo2L/TRAIL. Exp Cell Res 2007; 313: 2378-88.
-
(2007)
Exp Cell Res
, vol.313
, pp. 2378-2388
-
-
Gomez-Benito, M.1
Martinez-Lorenzo, M.J.2
Anel, A.3
Marzo, I.4
Naval, J.5
-
48
-
-
7344233085
-
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL
-
Emery JG, McDonnell P, Burke MB, Deen KC, Lyn S, Silverman C, et al. Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL. J Biol Chem 1998; 273: 14363-7.
-
(1998)
J Biol Chem
, vol.273
, pp. 14363-14367
-
-
Emery, J.G.1
McDonnell, P.2
Burke, M.B.3
Deen, K.C.4
Lyn, S.5
Silverman, C.6
-
49
-
-
0036467427
-
Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice
-
Cretney E, Takeda K, Yagita H, Glaccum M, Peschon JJ, Smyth MJ. Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice. J Immunol 2002; 168: 1356-61.
-
(2002)
J Immunol
, vol.168
, pp. 1356-1361
-
-
Cretney, E.1
Takeda, K.2
Yagita, H.3
Glaccum, M.4
Peschon, J.J.5
Smyth, M.J.6
-
50
-
-
45949102602
-
Does Apo2L/TRAIL play any physiologic role in osteoclastogenesis?
-
autor reply 13
-
Labrinidis A, Liapis V, Thai le M, Atkins GJ, Vincent C, Hay S, et al. Does Apo2L/TRAIL play any physiologic role in osteoclastogenesis? Blood 2008; 111: 5411-2; autor reply 13.
-
(2008)
Blood
, vol.111
, pp. 5411-5412
-
-
Labrinidis, A.1
Liapis, V.2
Thai Le, M.3
Atkins, G.J.4
Vincent, C.5
Hay, S.6
-
51
-
-
0033667778
-
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
-
Sprick MR, Weigand MA, Rieser E, Rauch CT, Juo P, Blenis J, et al. FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2. Immunity 2000; 12: 599-609.
-
(2000)
Immunity
, vol.12
, pp. 599-609
-
-
Sprick, M.R.1
Weigand, M.A.2
Rieser, E.3
Rauch, C.T.4
Juo, P.5
Blenis, J.6
-
52
-
-
0035824635
-
Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8
-
Kischkel FC, Lawrence DA, Tinel A, LeBlanc H, Virmani A, Schow P, et al. Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8. J Biol Chem 2001; 276: 46639-46.
-
(2001)
J Biol Chem
, vol.276
, pp. 46639-46
-
-
Kischkel, F.C.1
Lawrence, D.A.2
Tinel, A.3
Leblanc, H.4
Virmani, A.5
Schow, P.6
-
53
-
-
0035923653
-
Caspase-10 is an initiator caspase in death receptor signaling
-
Wang J, Chun HJ, Wong W, Spencer DM, Lenardo MJ. Caspase-10 is an initiator caspase in death receptor signaling. Proc Natl Acad Sci USA 2001; 98: 13884-8.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 13884-13888
-
-
Wang, J.1
Chun, H.J.2
Wong, W.3
Spencer, D.M.4
Lenardo, M.J.5
-
54
-
-
0037009370
-
Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8
-
Sprick MR, Rieser E, Stahl H, Grosse-Wilde A, Weigand MA, Walczak H. Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8. EMBO J 2002; 21: 4520-30.
-
(2002)
EMBO J
, vol.21
, pp. 4520-4530
-
-
Sprick, M.R.1
Rieser, E.2
Stahl, H.3
Grosse-Wilde, A.4
Weigand, M.A.5
Walczak, H.6
-
55
-
-
0032536771
-
Two CD95 (APO-1/Fas) signaling pathways
-
Scaffidi C, Fulda S, Srinivasan A, Friesen C, Li F, Tomaselli KJ, et al. Two CD95 (APO-1/Fas) signaling pathways. EMBO J 1998; 17: 1675-87.
-
(1998)
EMBO J
, vol.17
, pp. 1675-1687
-
-
Scaffidi, C.1
Fulda, S.2
Srinivasan, A.3
Friesen, C.4
Li, F.5
Tomaselli, K.J.6
-
56
-
-
0032555697
-
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
-
Li H, Zhu H, Xu CJ, Yuan J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998; 94: 491-501.
-
(1998)
Cell
, vol.94
, pp. 491-501
-
-
Li, H.1
Zhu, H.2
Xu, C.J.3
Yuan, J.4
-
57
-
-
0032555716
-
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
Luo X, Budihardjo I, Zou H, Slaughter C, Wang X. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 1998; 94: 481-90.
-
(1998)
Cell
, vol.94
, pp. 481-490
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
58
-
-
0035827569
-
Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex
-
Krueger A, Schmitz I, Baumann S, Krammer PH, Kirchhoff S. Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex. J Biol Chem 2001; 276: 20633-40.
-
(2001)
J Biol Chem
, vol.276
, pp. 20633-40
-
-
Krueger, A.1
Schmitz, I.2
Baumann, S.3
Krammer, P.H.4
Kirchhoff, S.5
-
59
-
-
0030970013
-
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
-
Thome M, Schneider P, Hofmann K, Fickenscher H, Meinl E, Neipel F, et al. Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors. Nature 1997; 386: 517-21.
-
(1997)
Nature
, vol.386
, pp. 517-521
-
-
Thome, M.1
Schneider, P.2
Hofmann, K.3
Fickenscher, H.4
Meinl, E.5
Neipel, F.6
-
60
-
-
0030800070
-
Inhibition of death receptor signals by cellular FLIP
-
Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, et al. Inhibition of death receptor signals by cellular FLIP. Nature 1997; 388: 190-5.
-
(1997)
Nature
, vol.388
, pp. 190-195
-
-
Irmler, M.1
Thome, M.2
Hahne, M.3
Schneider, P.4
Hofmann, K.5
Steiner, V.6
-
61
-
-
0037160117
-
The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex
-
Micheau O, Thome M, Schneider P, Holler N, Tschopp J, Nicholson DW, et al. The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex. J Biol Chem 2002; 277: 45162-71.
-
(2002)
J Biol Chem
, vol.277
, pp. 45162-71
-
-
Micheau, O.1
Thome, M.2
Schneider, P.3
Holler, N.4
Tschopp, J.5
Nicholson, D.W.6
-
62
-
-
0034905394
-
XIAP: Apoptotic brake and promising therapeutic target
-
Holcik M, Gibson H, Korneluk RG. XIAP: Apoptotic brake and promising therapeutic target. Apoptosis 2001; 6: 253-61.
-
(2001)
Apoptosis
, vol.6
, pp. 253-261
-
-
Holcik, M.1
Gibson, H.2
Korneluk, R.G.3
-
63
-
-
0034710649
-
Structural and biochemical basis of apoptotic activation by Smac/DIABLO
-
Chai J, Du C, Wu JW, Kyin S, Wang X, Shi Y. Structural and biochemical basis of apoptotic activation by Smac/DIABLO. Nature 2000; 406: 855-62.
-
(2000)
Nature
, vol.406
, pp. 855-862
-
-
Chai, J.1
Du, C.2
Wu, J.W.3
Kyin, S.4
Wang, X.5
Shi, Y.6
-
64
-
-
77956170550
-
New insights into apoptosis signaling by Apo2L/TRAIL
-
Gonzalvez F, Ashkenazi A. New insights into apoptosis signaling by Apo2L/TRAIL. Oncogene 2010; 29: 4752-65.
-
(2010)
Oncogene
, vol.29
, pp. 4752-4765
-
-
Gonzalvez, F.1
Ashkenazi, A.2
-
65
-
-
0030977847
-
Target protease specificity of the viral serpin CrmA. Analysis of five caspases
-
Zhou Q, Snipas S, Orth K, Muzio M, Dixit VM, Salvesen GS. Target protease specificity of the viral serpin CrmA. Analysis of five caspases. J Biol Chem 1997; 272: 7797-800.
-
(1997)
J Biol Chem
, vol.272
, pp. 7797-7800
-
-
Zhou, Q.1
Snipas, S.2
Orth, K.3
Muzio, M.4
Dixit, V.M.5
Salvesen, G.S.6
-
66
-
-
33845472476
-
Caspase inhibitors: Viral, cellular and chemical
-
Callus BA, Vaux DL. Caspase inhibitors: Viral, cellular and chemical. Cell Death Differ 2007; 14: 73-8.
-
(2007)
Cell Death Differ
, vol.14
, pp. 73-78
-
-
Callus, B.A.1
Vaux, D.L.2
-
67
-
-
34948894931
-
Death-receptor O-glycosylation controls tumorcell sensitivity to the proapoptotic ligand Apo2L/TRAIL
-
Wagner KW, Punnoose EA, Januario T, Lawrence DA, Pitti RM, Lancaster K, et al. Death-receptor O-glycosylation controls tumorcell sensitivity to the proapoptotic ligand Apo2L/TRAIL. Nat Med 2007; 13: 1070-7.
-
(2007)
Nat Med
, vol.13
, pp. 1070-1077
-
-
Wagner, K.W.1
Punnoose, E.A.2
Januario, T.3
Lawrence, D.A.4
Pitti, R.M.5
Lancaster, K.6
-
68
-
-
33745928465
-
Death-receptor activation halts clathrindependent endocytosis
-
Austin CD, Lawrence DA, Peden AA, Varfolomeev EE, Totpal K, De Maziere AM, et al. Death-receptor activation halts clathrindependent endocytosis. Proc Natl Acad Sci USA 2006; 103: 10283-8.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 10283-10288
-
-
Austin, C.D.1
Lawrence, D.A.2
Peden, A.A.3
Varfolomeev, E.E.4
Totpal, K.5
de Maziere, A.M.6
-
69
-
-
34250331231
-
Receptor-mediated endocytosis is not required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis
-
Kohlhaas SL, Craxton A, Sun XM, Pinkoski MJ, Cohen GM. Receptor-mediated endocytosis is not required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis. J Biol Chem 2007; 282: 12831-41.
-
(2007)
J Biol Chem
, vol.282
, pp. 12831-41
-
-
Kohlhaas, S.L.1
Craxton, A.2
Sun, X.M.3
Pinkoski, M.J.4
Cohen, G.M.5
-
70
-
-
65549085701
-
Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling
-
Jin Z, Li Y, Pitti R, Lawrence D, Pham VC, Lill JR, et al. Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling. Cell 2009; 137: 721-35.
-
(2009)
Cell
, vol.137
, pp. 721-735
-
-
Jin, Z.1
Li, Y.2
Pitti, R.3
Lawrence, D.4
Pham, V.C.5
Lill, J.R.6
-
72
-
-
0036687185
-
Characterization of the in vivo function of TNFalpha-related apoptosis-inducing ligand, TRAIL/Apo2L, using TRAIL/Apo2L gene-deficient mice
-
Sedger LM, Glaccum MB, Schuh JC, Kanaly ST, Williamson E, Kayagaki N, et al. Characterization of the in vivo function of TNFalpha-related apoptosis-inducing ligand, TRAIL/Apo2L, using TRAIL/Apo2L gene-deficient mice. Eur J Immunol 2002; 32: 2246-54.
-
(2002)
Eur J Immunol
, vol.32
, pp. 2246-2254
-
-
Sedger, L.M.1
Glaccum, M.B.2
Schuh, J.C.3
Kanaly, S.T.4
Williamson, E.5
Kayagaki, N.6
-
73
-
-
10344260656
-
TRAIL-R as a negative regulator of innate immune cell responses
-
Diehl GE, Yue HH, Hsieh K, Kuang AA, Ho M, Morici LA, et al. TRAIL-R as a negative regulator of innate immune cell responses. Immunity 2004; 21: 877-89.
-
(2004)
Immunity
, vol.21
, pp. 877-889
-
-
Diehl, G.E.1
Yue, H.H.2
Hsieh, K.3
Kuang, A.A.4
Ho, M.5
Morici, L.A.6
-
75
-
-
0033567099
-
Expression and function of TNF-related apoptosisinducing ligand on murine activated NK cells
-
Kayagaki N, Yamaguchi N, Nakayama M, Takeda K, Akiba H, Tsutsui H, et al. Expression and function of TNF-related apoptosisinducing ligand on murine activated NK cells. J Immunol 1999; 163: 1906-13.
-
(1999)
J Immunol
, vol.163
, pp. 1906-1913
-
-
Kayagaki, N.1
Yamaguchi, N.2
Nakayama, M.3
Takeda, K.4
Akiba, H.5
Tsutsui, H.6
-
76
-
-
0033583433
-
Monocyte-mediated tumoricidal activity via the tumor necrosis factor-related cytokine, TRAIL
-
Griffith TS, Wiley SR, Kubin MZ, Sedger LM, Maliszewski CR, Fanger NA. Monocyte-mediated tumoricidal activity via the tumor necrosis factor-related cytokine, TRAIL. J Exp Med 1999; 189: 1343-54.
-
(1999)
J Exp Med
, vol.189
, pp. 1343-1354
-
-
Griffith, T.S.1
Wiley, S.R.2
Kubin, M.Z.3
Sedger, L.M.4
Maliszewski, C.R.5
Fanger, N.A.6
-
77
-
-
0032701696
-
Human dendritic cells mediate cellular apoptosis via tumor necrosis factorrelated apoptosis-inducing ligand (TRAIL)
-
Fanger NA, Maliszewski CR, Schooley K, Griffith TS. Human dendritic cells mediate cellular apoptosis via tumor necrosis factorrelated apoptosis-inducing ligand (TRAIL). J Exp Med 1999; 190: 1155-64.
-
(1999)
J Exp Med
, vol.190
, pp. 1155-1164
-
-
Fanger, N.A.1
Maliszewski, C.R.2
Schooley, K.3
Griffith, T.S.4
-
78
-
-
0242509835
-
Regulation of soluble and surface-bound TRAIL in human T cells, B cells, and monocytes
-
Ehrlich S, Infante-Duarte C, Seeger B, Zipp F. Regulation of soluble and surface-bound TRAIL in human T cells, B cells, and monocytes. Cytokine 2003; 24: 244-53.
-
(2003)
Cytokine
, vol.24
, pp. 244-253
-
-
Ehrlich, S.1
Infante-Duarte, C.2
Seeger, B.3
Zipp, F.4
-
79
-
-
0034061453
-
Lipopolysaccharide induces expression of APO2 ligand/TRAIL in human monocytes and macrophages
-
Halaas O, Vik R, Ashkenazi A, Espevik T. Lipopolysaccharide induces expression of APO2 ligand/TRAIL in human monocytes and macrophages. Scand J Immunol 2000; 51: 244-50.
-
(2000)
Scand J Immunol
, vol.51
, pp. 244-250
-
-
Halaas, O.1
Vik, R.2
Ashkenazi, A.3
Espevik, T.4
-
80
-
-
0035894946
-
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in NK cell-mediated and IFN-gammadependent suppression of subcutaneous tumor growth
-
Takeda K, Smyth MJ, Cretney E, Hayakawa Y, Yamaguchi N, Yagita H, et al. Involvement of tumor necrosis factor-related apoptosis-inducing ligand in NK cell-mediated and IFN-gammadependent suppression of subcutaneous tumor growth. Cell Immunol 2001; 214: 194-200.
-
(2001)
Cell Immunol
, vol.214
, pp. 194-200
-
-
Takeda, K.1
Smyth, M.J.2
Cretney, E.3
Hayakawa, Y.4
Yamaguchi, N.5
Yagita, H.6
-
81
-
-
0035911242
-
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon gamma-dependent natural killer cell protection from tumor metastasis
-
Smyth MJ, Cretney E, Takeda K, Wiltrout RH, Sedger LM, Kayagaki N, et al. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon gamma-dependent natural killer cell protection from tumor metastasis. J Exp Med 2001; 193: 661-70.
-
(2001)
J Exp Med
, vol.193
, pp. 661-670
-
-
Smyth, M.J.1
Cretney, E.2
Takeda, K.3
Wiltrout, R.H.4
Sedger, L.M.5
Kayagaki, N.6
-
82
-
-
20144370572
-
TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver
-
Takeda K, Cretney E, Hayakawa Y, Ota T, Akiba H, Ogasawara K, et al. TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver. Blood 2005; 105: 2082-9.
-
(2005)
Blood
, vol.105
, pp. 2082-2089
-
-
Takeda, K.1
Cretney, E.2
Hayakawa, Y.3
Ota, T.4
Akiba, H.5
Ogasawara, K.6
-
83
-
-
0037530629
-
Plasmacytoid dendritic cellderived IFN-alpha induces TNF-related apoptosis-inducing ligand/Apo-2L-mediated antitumor activity by human monocytes following CpG oligodeoxynucleotide stimulation
-
Kemp TJ, Elzey BD, Griffith TS. Plasmacytoid dendritic cellderived IFN-alpha induces TNF-related apoptosis-inducing ligand/Apo-2L-mediated antitumor activity by human monocytes following CpG oligodeoxynucleotide stimulation. J Immunol 2003; 171: 212-8.
-
(2003)
J Immunol
, vol.171
, pp. 212-218
-
-
Kemp, T.J.1
Elzey, B.D.2
Griffith, T.S.3
-
84
-
-
0035339858
-
The involvement of TNFalpha-related apoptosis-inducing ligand in the enhanced cytotoxicity of IFN-beta-stimulated human dendritic cells to tumor cells
-
Liu S, Yu Y, Zhang M, Wang W, Cao X. The involvement of TNFalpha-related apoptosis-inducing ligand in the enhanced cytotoxicity of IFN-beta-stimulated human dendritic cells to tumor cells. J Immunol 2001; 166: 5407-15.
-
(2001)
J Immunol
, vol.166
, pp. 5407-5415
-
-
Liu, S.1
Yu, Y.2
Zhang, M.3
Wang, W.4
Cao, X.5
-
85
-
-
32244448339
-
Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity
-
Chan CW, Crafton E, Fan HN, Flook J, Yoshimura K, Skarica M, et al. Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity. Nat Med 2006; 12: 207-13.
-
(2006)
Nat Med
, vol.12
, pp. 207-213
-
-
Chan, C.W.1
Crafton, E.2
Fan, H.N.3
Flook, J.4
Yoshimura, K.5
Skarica, M.6
-
86
-
-
32244445715
-
A novel dendritic cell subset involved in tumor immunosurveillance
-
Taieb J, Chaput N, Menard C, Apetoh L, Ullrich E, Bonmort M, et al. A novel dendritic cell subset involved in tumor immunosurveillance. Nat Med 2006; 12: 214-9.
-
(2006)
Nat Med
, vol.12
, pp. 214-219
-
-
Taieb, J.1
Chaput, N.2
Menard, C.3
Apetoh, L.4
Ullrich, E.5
Bonmort, M.6
-
88
-
-
0033519303
-
Type I interferons (IFNs) regulate tumor necrosis factorrelated apoptosis-inducing ligand (TRAIL) expression on human T cells: A novel mechanism for the antitumor effects of type I IFNs
-
Kayagaki N, Yamaguchi N, Nakayama M, Eto H, Okumura K, Yagita H. Type I interferons (IFNs) regulate tumor necrosis factorrelated apoptosis-inducing ligand (TRAIL) expression on human T cells: A novel mechanism for the antitumor effects of type I IFNs. J Exp Med 1999; 189: 1451-60.
-
(1999)
J Exp Med
, vol.189
, pp. 1451-1460
-
-
Kayagaki, N.1
Yamaguchi, N.2
Nakayama, M.3
Eto, H.4
Okumura, K.5
Yagita, H.6
Type, I.7
-
89
-
-
20844451628
-
Human CD8+ T cell blasts are more sensitive than CD4+ T cell blasts to regulation by APO2L/TRAIL
-
Bosque A, Pardo J, Martinez-Lorenzo MJ, Lasierra P, Larrad L, Marzo I, et al. Human CD8+ T cell blasts are more sensitive than CD4+ T cell blasts to regulation by APO2L/TRAIL. Eur J Immunol 2005; 35: 1812-21.
-
(2005)
Eur J Immunol
, vol.35
, pp. 1812-1821
-
-
Bosque, A.1
Pardo, J.2
Martinez-Lorenzo, M.J.3
Lasierra, P.4
Larrad, L.5
Marzo, I.6
-
90
-
-
0033767690
-
Exosome: From internal vesicle of the multivesicular body to intercellular signaling device
-
Denzer K, Kleijmeer MJ, Heijnen HF, Stoorvogel W, Geuze HJ. Exosome: From internal vesicle of the multivesicular body to intercellular signaling device. J Cell Sci 2000; 113 Pt 19: 3365-74.
-
(2000)
J Cell Sci
, vol.113
, Issue.Pt 19
, pp. 3365-3374
-
-
Denzer, K.1
Kleijmeer, M.J.2
Heijnen, H.F.3
Stoorvogel, W.4
Geuze, H.J.5
-
91
-
-
0035892735
-
Differential secretion of Fas ligand-or APO2 ligand/TNF-related apoptosis-inducing ligand-carrying microvesicles during activation-induced death of human T cells
-
Monleon I, Martinez-Lorenzo MJ, Monteagudo L, Lasierra P, Taules M, Iturralde M, et al. Differential secretion of Fas ligand-or APO2 ligand/TNF-related apoptosis-inducing ligand-carrying microvesicles during activation-induced death of human T cells. J Immunol 2001; 167: 6736-44.
-
(2001)
J Immunol
, vol.167
, pp. 6736-6744
-
-
Monleon, I.1
Martinez-Lorenzo, M.J.2
Monteagudo, L.3
Lasierra, P.4
Taules, M.5
Iturralde, M.6
-
92
-
-
0344731338
-
Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles
-
Martinez-Lorenzo MJ, Anel A, Gamen S, Monle n I, Lasierra P, Larrad L, et al. Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles. J Immunol 1999; 163: 1274-81.
-
(1999)
J Immunol
, vol.163
, pp. 1274-1281
-
-
Martinez-Lorenzo, M.J.1
Anel, A.2
Gamen, S.3
Monlen, I.4
Lasierra, P.5
Larrad, L.6
-
93
-
-
0033933918
-
Expression of TRAIL receptors in human autoreactive and foreign antigen-specific T cells
-
Wendling U, Walczak H, Dorr J, Jaboci C, Weller M, Krammer PH, et al. Expression of TRAIL receptors in human autoreactive and foreign antigen-specific T cells. Cell Death Differ 2000; 7: 637-44.
-
(2000)
Cell Death Differ
, vol.7
, pp. 637-644
-
-
Wendling, U.1
Walczak, H.2
Dorr, J.3
Jaboci, C.4
Weller, M.5
Krammer, P.H.6
-
94
-
-
4944243249
-
Activated human NK and CD8+ T cells express both TNFrelated apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated cytotoxicity
-
Mirandola P, Ponti C, Gobbi G, Sponzilli I, Vaccarezza M, Cocco L, et al. Activated human NK and CD8+ T cells express both TNFrelated apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated cytotoxicity. Blood 2004; 104: 2418-24.
-
(2004)
Blood
, vol.104
, pp. 2418-2424
-
-
Mirandola, P.1
Ponti, C.2
Gobbi, G.3
Sponzilli, I.4
Vaccarezza, M.5
Cocco, L.6
-
95
-
-
0030155964
-
Activation of apoptosis by Apo-2 ligand is independent of FADD but blocked by CrmA
-
Marsters SA, Pitti RM, Donahue CJ, Ruppert S, Bauer KD, Ashkenazi A. Activation of apoptosis by Apo-2 ligand is independent of FADD but blocked by CrmA. Curr Biol 1996; 6: 750-2.
-
(1996)
Curr Biol
, vol.6
, pp. 750-752
-
-
Marsters, S.A.1
Pitti, R.M.2
Donahue, C.J.3
Ruppert, S.4
Bauer, K.D.5
Ashkenazi, A.6
-
96
-
-
0028795758
-
Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)
-
Dhein J, Walczak H, Baumler C, Debatin KM, Krammer PH. Autocrine T-cell suicide mediated by APO-1/(Fas/CD95). Nature 1995; 373: 438-41.
-
(1995)
Nature
, vol.373
, pp. 438-441
-
-
Dhein, J.1
Walczak, H.2
Baumler, C.3
Debatin, K.M.4
Krammer, P.H.5
-
97
-
-
1142287412
-
Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death
-
Muppidi JR, Siegel RM. Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death. Nat Immunol 2004; 5: 182-9.
-
(2004)
Nat Immunol
, vol.5
, pp. 182-189
-
-
Muppidi, J.R.1
Siegel, R.M.2
-
98
-
-
16844375891
-
Down-regulation of normal human T cell blast activation: Roles of APO2L/TRAIL, FasL, and c-FLIP, Bim, or Bclx isoform expression
-
Bosque A, Pardo J, Martinez-Lorenzo MJ, Iturralde M, Marzo I, Pineiro A, et al. Down-regulation of normal human T cell blast activation: Roles of APO2L/TRAIL, FasL, and c-FLIP, Bim, or Bclx isoform expression. J Leukoc Biol 2005; 77: 568-78.
-
(2005)
J Leukoc Biol
, vol.77
, pp. 568-578
-
-
Bosque, A.1
Pardo, J.2
Martinez-Lorenzo, M.J.3
Iturralde, M.4
Marzo, I.5
Pineiro, A.6
-
99
-
-
33748789594
-
Apoptosis by IL-2 deprivation in human CD8+ T cell blasts predominates over death receptor ligation, requires Bim expression and is associated with Mcl-1 loss
-
Bosque A, Marzo I, Naval J, Anel A. Apoptosis by IL-2 deprivation in human CD8+ T cell blasts predominates over death receptor ligation, requires Bim expression and is associated with Mcl-1 loss. Mol Immunol 2007; 44: 1446-53.
-
(2007)
Mol Immunol
, vol.44
, pp. 1446-1453
-
-
Bosque, A.1
Marzo, I.2
Naval, J.3
Anel, A.4
-
100
-
-
5644241900
-
T-lymphocyte death during shutdown of an immune response
-
Strasser A, Pellegrini M. T-lymphocyte death during shutdown of an immune response. Trends Immunol 2004; 25: 610-5.
-
(2004)
Trends Immunol
, vol.25
, pp. 610-615
-
-
Strasser, A.1
Pellegrini, M.2
-
101
-
-
0037442136
-
Role of CD4 T cell help and costimulation in CD8 T cell responses during Listeria monocytogenes infection
-
Shedlock DJ, Whitmire JK, Tan J, MacDonald AS, Ahmed R, Shen H. Role of CD4 T cell help and costimulation in CD8 T cell responses during Listeria monocytogenes infection. J Immunol 2003; 170: 2053-63.
-
(2003)
J Immunol
, vol.170
, pp. 2053-2063
-
-
Shedlock, D.J.1
Whitmire, J.K.2
Tan, J.3
Macdonald, A.S.4
Ahmed, R.5
Shen, H.6
-
102
-
-
14544288632
-
CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death
-
Janssen EM, Droin NM, Lemmens EE, Pinkoski MJ, Bensinger SJ, Ehst BD, et al. CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death. Nature 2005; 434: 88-93.
-
(2005)
Nature
, vol.434
, pp. 88-93
-
-
Janssen, E.M.1
Droin, N.M.2
Lemmens, E.E.3
Pinkoski, M.J.4
Bensinger, S.J.5
Ehst, B.D.6
-
103
-
-
80052833830
-
-
US20110038855
-
Schoenberger, S.P., Green, D.R., Janssen, E.M., Droin, N.M. TRAIL and method of modulating T cell active and adaptative immune responses using TRAIL. US20110038855 (2011).
-
(2011)
TRAIL and Method of Modulating T Cell Active and Adaptative Immune Responses Using TRAIL
-
-
Schoenberger, S.P.1
Green, D.R.2
Janssen, E.M.3
Droin, N.M.4
-
104
-
-
0038702580
-
Reciprocal expression of TRAIL and CD95L in Th1 and Th2 cells: Role of apoptosis in T helper subset differentiation
-
Zhang XR, Zhang LY, Devadas S, Li L, Keegan AD, Shi YF. Reciprocal expression of TRAIL and CD95L in Th1 and Th2 cells: Role of apoptosis in T helper subset differentiation. Cell Death Differ 2003; 10: 203-10.
-
(2003)
Cell Death Differ
, vol.10
, pp. 203-210
-
-
Zhang, X.R.1
Zhang, L.Y.2
Devadas, S.3
Li, L.4
Keegan, A.D.5
Shi, Y.F.6
-
105
-
-
9144232224
-
The role of activation-induced cell death in the differentiation of T-helper-cell subsets
-
Roberts AI, Devadas S, Zhang X, Zhang L, Keegan A, Greeneltch K, et al. The role of activation-induced cell death in the differentiation of T-helper-cell subsets. Immunol Res 2003; 28: 285-93.
-
(2003)
Immunol Res
, vol.28
, pp. 285-293
-
-
Roberts, A.I.1
Devadas, S.2
Zhang, X.3
Zhang, L.4
Keegan, A.5
Greeneltch, K.6
-
106
-
-
36248995916
-
Involvement of cellular death in TRAIL/DR5-dependent suppression induced by CD4(+)CD25(+) regulatory T cells
-
Ren X, Ye F, Jiang Z, Chu Y, Xiong S, Wang Y. Involvement of cellular death in TRAIL/DR5-dependent suppression induced by CD4(+)CD25(+) regulatory T cells. Cell Death Differ 2007; 14: 2076-84.
-
(2007)
Cell Death Differ
, vol.14
, pp. 2076-2084
-
-
Ren, X.1
Ye, F.2
Jiang, Z.3
Chu, Y.4
Xiong, S.5
Wang, Y.6
-
107
-
-
63849083402
-
Tumor necrosis factor-related apoptosis-inducing ligand inhibits experimental autoimmune thyroiditis by the expansion of CD4+CD25+ regulatory T cells
-
Wang SH, Chen GH, Fan Y, Van Antwerp M, Baker JR, Jr. Tumor necrosis factor-related apoptosis-inducing ligand inhibits experimental autoimmune thyroiditis by the expansion of CD4+CD25+ regulatory T cells. Endocrinology 2009; 150: 2000-7.
-
(2009)
Endocrinology
, vol.150
, pp. 2000-2007
-
-
Wang, S.H.1
Chen, G.H.2
Fan, Y.3
van Antwerp, M.4
Baker Jr., J.R.5
-
108
-
-
33846211913
-
Involvement of regulatory T cells in the experimental autoimmune encephalomyelitis-preventive effect of dendritic cells expressing myelin oligodendrocyte glycoprotein plus TRAIL
-
Hirata S, Matsuyoshi H, Fukuma D, Kurisaki A, Uemura Y, Nishimura Y, et al. Involvement of regulatory T cells in the experimental autoimmune encephalomyelitis-preventive effect of dendritic cells expressing myelin oligodendrocyte glycoprotein plus TRAIL. J Immunol 2007; 178: 918-25.
-
(2007)
J Immunol
, vol.178
, pp. 918-925
-
-
Hirata, S.1
Matsuyoshi, H.2
Fukuma, D.3
Kurisaki, A.4
Uemura, Y.5
Nishimura, Y.6
-
109
-
-
12744280983
-
TRAIL and thymocyte apoptosis: Not so deadly?
-
Corazza N, Brumatti G, Jakob S, Villunger A, Brunner T. TRAIL and thymocyte apoptosis: Not so deadly? Cell Death Differ 2004; 11 (Suppl 2): S213-5.
-
(2004)
Cell Death Differ
, vol.11
, Issue.SUPPL. 2
, pp. 213-215
-
-
Corazza, N.1
Brumatti, G.2
Jakob, S.3
Villunger, A.4
Brunner, T.5
-
110
-
-
0042624821
-
Normal thymocyte negative selection in TRAIL-deficient mice
-
Cretney E, Uldrich AP, Berzins SP, Strasser A, Godfrey DI, Smyth MJ. Normal thymocyte negative selection in TRAIL-deficient mice. J Exp Med 2003; 198: 491-6.
-
(2003)
J Exp Med
, vol.198
, pp. 491-496
-
-
Cretney, E.1
Uldrich, A.P.2
Berzins, S.P.3
Strasser, A.4
Godfrey, D.I.5
Smyth, M.J.6
-
111
-
-
33645091240
-
TNFrelated apoptosis-inducing ligand as a therapeutic agent in autoimmunity and cancer
-
Cretney E, Shanker A, Yagita H, Smyth MJ, Sayers TJ. TNFrelated apoptosis-inducing ligand as a therapeutic agent in autoimmunity and cancer. Immunol Cell Biol 2006; 84: 87-98.
-
(2006)
Immunol Cell Biol
, vol.84
, pp. 87-98
-
-
Cretney, E.1
Shanker, A.2
Yagita, H.3
Smyth, M.J.4
Sayers, T.J.5
-
112
-
-
0033565590
-
IFN-gamma mediates a novel antiviral activity through dynamic modulation of TRAIL and TRAIL receptor expression
-
Sedger LM, Shows DM, Blanton RA, Peschon JJ, Goodwin RG, Cosman D, et al. IFN-gamma mediates a novel antiviral activity through dynamic modulation of TRAIL and TRAIL receptor expression. J Immunol 1999; 163: 920-6.
-
(1999)
J Immunol
, vol.163
, pp. 920-926
-
-
Sedger, L.M.1
Shows, D.M.2
Blanton, R.A.3
Peschon, J.J.4
Goodwin, R.G.5
Cosman, D.6
-
113
-
-
0035179965
-
Antiviral response by natural killer cells through TRAIL gene induction by IFN-alpha/beta
-
Sato K, Hida S, Takayanagi H, Yokochi T, Kayagaki N, Takeda K, et al. Antiviral response by natural killer cells through TRAIL gene induction by IFN-alpha/beta. Eur J Immunol 2001; 31: 3138-46.
-
(2001)
Eur J Immunol
, vol.31
, pp. 3138-3146
-
-
Sato, K.1
Hida, S.2
Takayanagi, H.3
Yokochi, T.4
Kayagaki, N.5
Takeda, K.6
-
114
-
-
58149288679
-
CD8 T cells utilize TRAIL to control influenza virus infection
-
Brincks EL, Katewa A, Kucaba TA, Griffith TS, Legge KL. CD8 T cells utilize TRAIL to control influenza virus infection. J Immunol 2008; 181: 4918-25.
-
(2008)
J Immunol
, vol.181
, pp. 4918-4925
-
-
Brincks, E.L.1
Katewa, A.2
Kucaba, T.A.3
Griffith, T.S.4
Legge, K.L.5
-
115
-
-
26644474569
-
Involvement of tumor necrosis factor-related apoptosisinducing ligand and tumor necrosis factor-related apoptosisinducing ligand receptors in viral hepatic diseases
-
Saitou Y, Shiraki K, Fuke H, Inoue T, Miyashita K, Yamanaka Y, et al. Involvement of tumor necrosis factor-related apoptosisinducing ligand and tumor necrosis factor-related apoptosisinducing ligand receptors in viral hepatic diseases. Hum Pathol 2005; 36: 1066-73.
-
(2005)
Hum Pathol
, vol.36
, pp. 1066-1073
-
-
Saitou, Y.1
Shiraki, K.2
Fuke, H.3
Inoue, T.4
Miyashita, K.5
Yamanaka, Y.6
-
116
-
-
0037268529
-
Involvement of TRAIL and its receptors in viral hepatitis
-
Mundt B, Kuhnel F, Zender L, Paul Y, Tillmann H, Trautwein C, et al. Involvement of TRAIL and its receptors in viral hepatitis. Faseb J 2003; 17: 94-6.
-
(2003)
Faseb J
, vol.17
, pp. 94-96
-
-
Mundt, B.1
Kuhnel, F.2
Zender, L.3
Paul, Y.4
Tillmann, H.5
Trautwein, C.6
-
117
-
-
24144489702
-
Proteasome inhibition sensitizes hepatocellular carcinoma cells, but not human hepatocytes, to TRAIL
-
Ganten TM, Koschny R, Haas TL, Sykora J, Li-Weber M, Herzer K, et al. Proteasome inhibition sensitizes hepatocellular carcinoma cells, but not human hepatocytes, to TRAIL. Hepatology 2005; 42: 588-97.
-
(2005)
Hepatology
, vol.42
, pp. 588-597
-
-
Ganten, T.M.1
Koschny, R.2
Haas, T.L.3
Sykora, J.4
Li-Weber, M.5
Herzer, K.6
-
119
-
-
6344241438
-
Reduced apoptosis and ameliorated listeriosis in TRAIL-null mice
-
Zheng SJ, Jiang J, Shen H, Chen YH. Reduced apoptosis and ameliorated listeriosis in TRAIL-null mice. J Immunol 2004; 173: 5652-8.
-
(2004)
J Immunol
, vol.173
, pp. 5652-5658
-
-
Zheng, S.J.1
Jiang, J.2
Shen, H.3
Chen, Y.H.4
-
120
-
-
0033988563
-
Measles virus induces functional TRAIL production by human dendritic cells
-
Vidalain PO, Azocar O, Lamouille B, Astier A, Rabourdin-Combe C, Servet-Delprat C. Measles virus induces functional TRAIL production by human dendritic cells. J Virol 2000; 74: 556-9.
-
(2000)
J Virol
, vol.74
, pp. 556-559
-
-
Vidalain, P.O.1
Azocar, O.2
Lamouille, B.3
Astier, A.4
Rabourdin-Combe, C.5
Servet-Delprat, C.6
-
121
-
-
27744560468
-
CD4+ T-cell death induced by infectious and noninfectious HIV-1: Role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis
-
Herbeuval JP, Grivel JC, Boasso A, Hardy AW, Chougnet C, Dolan MJ, et al. CD4+ T-cell death induced by infectious and noninfectious HIV-1: Role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis. Blood 2005; 106: 3524-31.
-
(2005)
Blood
, vol.106
, pp. 3524-3531
-
-
Herbeuval, J.P.1
Grivel, J.C.2
Boasso, A.3
Hardy, A.W.4
Chougnet, C.5
Dolan, M.J.6
-
122
-
-
0034329318
-
Mechanisms of HIVassociated lymphocyte apoptosis
-
Badley AD, Pilon AA, Landay A, Lynch DH. Mechanisms of HIVassociated lymphocyte apoptosis. Blood 2000; 96: 2951-64.
-
(2000)
Blood
, vol.96
, pp. 2951-2964
-
-
Badley, A.D.1
Pilon, A.A.2
Landay, A.3
Lynch, D.H.4
-
123
-
-
0035809318
-
Critical contribution of tumor necrosis factor-related apoptosisinducing ligand (TRAIL) to apoptosis of human CD4+ T cells in HIV-1-infected hu-PBL-NOD-SCID mice
-
Miura Y, Misawa N, Maeda N, Inagaki Y, Tanaka Y, Ito M, et al. Critical contribution of tumor necrosis factor-related apoptosisinducing ligand (TRAIL) to apoptosis of human CD4+ T cells in HIV-1-infected hu-PBL-NOD-SCID mice. J Exp Med 2001; 193: 651-60.
-
(2001)
J Exp Med
, vol.193
, pp. 651-660
-
-
Miura, Y.1
Misawa, N.2
Maeda, N.3
Inagaki, Y.4
Tanaka, Y.5
Ito, M.6
-
124
-
-
15244358107
-
TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected patients and its in vitro production by antigenpresenting cells
-
Herbeuval JP, Boasso A, Grivel JC, Hardy AW, Anderson SA, Dolan MJ, et al. TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected patients and its in vitro production by antigenpresenting cells. Blood 2005; 105: 2458-64.
-
(2005)
Blood
, vol.105
, pp. 2458-2464
-
-
Herbeuval, J.P.1
Boasso, A.2
Grivel, J.C.3
Hardy, A.W.4
Anderson, S.A.5
Dolan, M.J.6
-
125
-
-
0034765429
-
Induction of cell death in human immunodeficiency virus-infected macrophages and resting memory CD4 T cells by TRAIL/Apo2l
-
Lum JJ, Pilon AA, Sanchez-Dardon J, Phenix BN, Kim JE, Mihowich J, et al. Induction of cell death in human immunodeficiency virus-infected macrophages and resting memory CD4 T cells by TRAIL/Apo2l. J Virol 2001; 75: 11128-36.
-
(2001)
J Virol
, vol.75
, pp. 11128-36
-
-
Lum, J.J.1
Pilon, A.A.2
Sanchez-Dardon, J.3
Phenix, B.N.4
Kim, J.E.5
Mihowich, J.6
-
127
-
-
37349047431
-
TRAIL is a novel antiviral protein against dengue virus
-
Warke RV, Martin KJ, Giaya K, Shaw SK, Rothman AL, Bosch I. TRAIL is a novel antiviral protein against dengue virus. J Virol 2008; 82: 555-64.
-
(2008)
J Virol
, vol.82
, pp. 555-564
-
-
Warke, R.V.1
Martin, K.J.2
Giaya, K.3
Shaw, S.K.4
Rothman, A.L.5
Bosch, I.6
-
128
-
-
0036852241
-
Cancer immunoediting: From immunosurveillance to tumor escape
-
Dunn GP, Bruce AT, Ikeda H, Old LJ, Schreiber RD. Cancer immunoediting: From immunosurveillance to tumor escape. Nat Immunol 2002; 3: 991-8.
-
(2002)
Nat Immunol
, vol.3
, pp. 991-998
-
-
Dunn, G.P.1
Bruce, A.T.2
Ikeda, H.3
Old, L.J.4
Schreiber, R.D.5
-
129
-
-
4143141823
-
The immunobiology of cancer immunosurveillance and immunoediting
-
Dunn GP, Old LJ, Schreiber RD. The immunobiology of cancer immunosurveillance and immunoediting. Immunity 2004; 21: 137-48.
-
(2004)
Immunity
, vol.21
, pp. 137-148
-
-
Dunn, G.P.1
Old, L.J.2
Schreiber, R.D.3
-
130
-
-
0032713075
-
Safety and antitumor activity of recombinant soluble Apo2 ligand
-
Ashkenazi A, Pai RC, Fong S, Leung S, Lawrence DA, Marsters SA, et al. Safety and antitumor activity of recombinant soluble Apo2 ligand. J Clin Invest 1999; 104: 155-62.
-
(1999)
J Clin Invest
, vol.104
, pp. 155-162
-
-
Ashkenazi, A.1
Pai, R.C.2
Fong, S.3
Leung, S.4
Lawrence, D.A.5
Marsters, S.A.6
-
131
-
-
0037226644
-
Tumor necrosis factor-related apoptosis-inducing ligandmediated apoptosis is an important endogenous mechanism for resistance to liver metastases in murine renal cancer
-
Seki N, Hayakawa Y, Brooks AD, Wine J, Wiltrout RH, Yagita H, et al. Tumor necrosis factor-related apoptosis-inducing ligandmediated apoptosis is an important endogenous mechanism for resistance to liver metastases in murine renal cancer. Cancer Res 2003; 63: 207-13.
-
(2003)
Cancer Res
, vol.63
, pp. 207-213
-
-
Seki, N.1
Hayakawa, Y.2
Brooks, A.D.3
Wine, J.4
Wiltrout, R.H.5
Yagita, H.6
-
132
-
-
0037148518
-
Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development
-
Takeda K, Smyth MJ, Cretney E, Hayakawa Y, Kayagaki N, Yagita H, et al. Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development. J Exp Med 2002; 195: 161-9.
-
(2002)
J Exp Med
, vol.195
, pp. 161-169
-
-
Takeda, K.1
Smyth, M.J.2
Cretney, E.3
Hayakawa, Y.4
Kayagaki, N.5
Yagita, H.6
-
133
-
-
0001130662
-
Alterations of the DR5/TRAIL receptor 2 gene in non-small cell lung cancers
-
Lee SH, Shin MS, Kim HS, Lee HK, Park WS, Kim SY, et al. Alterations of the DR5/TRAIL receptor 2 gene in non-small cell lung cancers. Cancer Res 1999; 59: 5683-6.
-
(1999)
Cancer Res
, vol.59
, pp. 5683-5686
-
-
Lee, S.H.1
Shin, M.S.2
Kim, H.S.3
Lee, H.K.4
Park, W.S.5
Kim, S.Y.6
-
134
-
-
17744364468
-
Somatic mutations of TRAIL-receptor 1 and TRAIL-receptor 2 genes in non-Hodgkin's lymphoma
-
Lee SH, Shin MS, Kim HS, Lee HK, Park WS, Kim SY, et al. Somatic mutations of TRAIL-receptor 1 and TRAIL-receptor 2 genes in non-Hodgkin's lymphoma. Oncogene 2001; 20: 399-403.
-
(2001)
Oncogene
, vol.20
, pp. 399-403
-
-
Lee, S.H.1
Shin, M.S.2
Kim, H.S.3
Lee, H.K.4
Park, W.S.5
Kim, S.Y.6
-
135
-
-
0035394722
-
Mutations of tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1) and receptor 2 (TRAIL-R2) genes in metastatic breast cancers
-
Shin MS, Kim HS, Lee SH, Park WS, Kim SY, Park JY, et al. Mutations of tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1) and receptor 2 (TRAIL-R2) genes in metastatic breast cancers. Cancer Res 2001; 61: 4942-6.
-
(2001)
Cancer Res
, vol.61
, pp. 4942-4946
-
-
Shin, M.S.1
Kim, H.S.2
Lee, S.H.3
Park, W.S.4
Kim, S.Y.5
Park, J.Y.6
-
136
-
-
0034901512
-
Nucleotide substitution in the ectodomain of trail receptor DR4 is associated with lung cancer and head and neck cancer
-
Fisher MJ, Virmani AK, Wu L, Aplenc R, Harper JC, Powell SM, et al. Nucleotide substitution in the ectodomain of trail receptor DR4 is associated with lung cancer and head and neck cancer. Clin Cancer Res 2001; 7: 1688-97.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1688-1697
-
-
Fisher, M.J.1
Virmani, A.K.2
Wu, L.3
Aplenc, R.4
Harper, J.C.5
Powell, S.M.6
-
137
-
-
21344474349
-
Contribution of epigenetic silencing of tumor necrosis factorrelated apoptosis inducing ligand receptor 1 (DR4) to TRAIL resistance and ovarian cancer
-
Horak P, Pils D, Haller G, Pribill I, Roessler M, Tomek S, et al. Contribution of epigenetic silencing of tumor necrosis factorrelated apoptosis inducing ligand receptor 1 (DR4) to TRAIL resistance and ovarian cancer. Mol Cancer Res 2005; 3: 335-43.
-
(2005)
Mol Cancer Res
, vol.3
, pp. 335-343
-
-
Horak, P.1
Pils, D.2
Haller, G.3
Pribill, I.4
Roessler, M.5
Tomek, S.6
-
138
-
-
67649300721
-
Genes that mediate breast cancer metastasis to the brain
-
Bos PD, Zhang XH, Nadal C, Shu W, Gomis RR, Nguyen DX, et al. Genes that mediate breast cancer metastasis to the brain. Nature 2009; 459: 1005-9.
-
(2009)
Nature
, vol.459
, pp. 1005-1009
-
-
Bos, P.D.1
Zhang, X.H.2
Nadal, C.3
Shu, W.4
Gomis, R.R.5
Nguyen, D.X.6
-
139
-
-
27144489394
-
Cutting edge: TRAIL deficiency accelerates hematological malignancies
-
Zerafa N, Westwood JA, Cretney E, Mitchell S, Waring P, Iezzi M, et al. Cutting edge: TRAIL deficiency accelerates hematological malignancies. J Immunol 2005; 175: 5586-90.
-
(2005)
J Immunol
, vol.175
, pp. 5586-5590
-
-
Zerafa, N.1
Westwood, J.A.2
Cretney, E.3
Mitchell, S.4
Waring, P.5
Iezzi, M.6
-
140
-
-
38149139518
-
TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis
-
Finnberg N, Klein-Szanto AJ, El-Deiry WS. TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis. J Clin Invest 2008; 118: 111-23.
-
(2008)
J Clin Invest
, vol.118
, pp. 111-123
-
-
Finnberg, N.1
Klein-Szanto, A.J.2
El-Deiry, W.S.3
-
141
-
-
38149122326
-
TRAIL-R deficiency in mice enhances lymph node metastasis without affecting primary tumor development
-
Grosse-Wilde A, Voloshanenko O, Bailey SL, Longton GM, Schaefer U, Csernok AI, et al. TRAIL-R deficiency in mice enhances lymph node metastasis without affecting primary tumor development. J Clin Invest 2008; 118: 100-10.
-
(2008)
J Clin Invest
, vol.118
, pp. 100-110
-
-
Grosse-Wilde, A.1
Voloshanenko, O.2
Bailey, S.L.3
Longton, G.M.4
Schaefer, U.5
Csernok, A.I.6
-
142
-
-
11844305926
-
Loss of TRAIL-R does not affect thymic or intestinal tumor development in p53 and adenomatous polyposis coli mutant mice
-
Yue HH, Diehl GE, Winoto A. Loss of TRAIL-R does not affect thymic or intestinal tumor development in p53 and adenomatous polyposis coli mutant mice. Cell Death Differ 2005; 12: 94-7.
-
(2005)
Cell Death Differ
, vol.12
, pp. 94-97
-
-
Yue, H.H.1
Diehl, G.E.2
Winoto, A.3
-
143
-
-
77951476070
-
Extreme lymphoproliferative disease and fatal autoimmune thrombocytopenia in FasL and TRAIL doubledeficient mice
-
Sedger LM, Katewa A, Pettersen AK, Osvath SR, Farrell GC, Stewart GJ, et al. Extreme lymphoproliferative disease and fatal autoimmune thrombocytopenia in FasL and TRAIL doubledeficient mice. Blood 2010; 115: 3258-68.
-
(2010)
Blood
, vol.115
, pp. 3258-3268
-
-
Sedger, L.M.1
Katewa, A.2
Pettersen, A.K.3
Osvath, S.R.4
Farrell, G.C.5
Stewart, G.J.6
-
144
-
-
0041820127
-
Critical roles of tumor necrosis factor-related apoptosis-inducing ligand in type 1 diabetes
-
Lamhamedi-Cherradi SE, Zheng S, Tisch RM, Chen YH. Critical roles of tumor necrosis factor-related apoptosis-inducing ligand in type 1 diabetes. Diabetes 2003; 52: 2274-8.
-
(2003)
Diabetes
, vol.52
, pp. 2274-2278
-
-
Lamhamedi-Cherradi, S.E.1
Zheng, S.2
Tisch, R.M.3
Chen, Y.H.4
-
145
-
-
0041765727
-
Blockade of tumor necrosis factor-related apoptosis-inducing ligand exacerbates type 1 diabetes in NOD mice
-
Mi QS, Ly D, Lamhamedi-Cherradi SE, Salojin KV, Zhou L, Grattan M, et al. Blockade of tumor necrosis factor-related apoptosis-inducing ligand exacerbates type 1 diabetes in NOD mice. Diabetes 2003; 52: 1967-75.
-
(2003)
Diabetes
, vol.52
, pp. 1967-1975
-
-
Mi, Q.S.1
Ly, D.2
Lamhamedi-Cherradi, S.E.3
Salojin, K.V.4
Zhou, L.5
Grattan, M.6
-
146
-
-
75649097496
-
Adenovirus-mediated TRAIL gene (Ad5hTRAIL) delivery into pancreatic islets prolongs normoglycemia in streptozotocininduced diabetic rats
-
Dirice E, Sanlioglu AD, Kahraman S, Ozturk S, Balci MK, Omer A, et al. Adenovirus-mediated TRAIL gene (Ad5hTRAIL) delivery into pancreatic islets prolongs normoglycemia in streptozotocininduced diabetic rats. Hum Gene Ther 2009; 20: 1177-89.
-
(2009)
Hum Gene Ther
, vol.20
, pp. 1177-1189
-
-
Dirice, E.1
Sanlioglu, A.D.2
Kahraman, S.3
Ozturk, S.4
Balci, M.K.5
Omer, A.6
-
147
-
-
78649876238
-
Systemic delivery of TNF-related apoptosis-inducing ligand (TRAIL) elevates levels of tissue inhibitor of metalloproteinase-1 (TIMP-1) and prevents type 1 diabetes in nonobese diabetic mice
-
Kang S, Park EJ, Joe Y, Seo E, Park MK, Seo SY, et al. Systemic delivery of TNF-related apoptosis-inducing ligand (TRAIL) elevates levels of tissue inhibitor of metalloproteinase-1 (TIMP-1) and prevents type 1 diabetes in nonobese diabetic mice. Endocrinology 2010; 151: 5638-46.
-
(2010)
Endocrinology
, vol.151
, pp. 5638-5646
-
-
Kang, S.1
Park, E.J.2
Joe, Y.3
Seo, E.4
Park, M.K.5
Seo, S.Y.6
-
148
-
-
26844490988
-
Death ligand tumor necrosis factor-related apoptosis-inducing ligand inhibits experimental autoimmune thyroiditis
-
Wang SH, Cao Z, Wolf JM, Van Antwerp M, Baker JR, Jr. Death ligand tumor necrosis factor-related apoptosis-inducing ligand inhibits experimental autoimmune thyroiditis. Endocrinology 2005; 146: 4721-6.
-
(2005)
Endocrinology
, vol.146
, pp. 4721-4726
-
-
Wang, S.H.1
Cao, Z.2
Wolf, J.M.3
van Antwerp, M.4
Baker Jr., J.R.5
-
149
-
-
57149113729
-
A critical role for TRAIL in resolution of granulomatous experimental autoimmune thyroiditis
-
Fang Y, Sharp GC, Yagita H, Braley-Mullen H. A critical role for TRAIL in resolution of granulomatous experimental autoimmune thyroiditis. J Pathol 2008; 216: 505-13.
-
(2008)
J Pathol
, vol.216
, pp. 505-513
-
-
Fang, Y.1
Sharp, G.C.2
Yagita, H.3
Braley-Mullen, H.4
-
150
-
-
0035863835
-
Roles of TNF-related apoptosis-inducing ligand in experimental autoimmune encephalomyelitis
-
Hilliard B, Wilmen A, Seidel C, Liu TS, Goke R, Chen Y. Roles of TNF-related apoptosis-inducing ligand in experimental autoimmune encephalomyelitis. J Immunol 2001; 166: 1314-9.
-
(2001)
J Immunol
, vol.166
, pp. 1314-1319
-
-
Hilliard, B.1
Wilmen, A.2
Seidel, C.3
Liu, T.S.4
Goke, R.5
Chen, Y.6
-
152
-
-
29144522877
-
TNF-related apoptosis-inducing ligand (TRAIL)/Apo2L suppresses experimental autoimmune encephalomyelitis in mice
-
Cretney E, McQualter JL, Kayagaki N, Yagita H, Bernard CC, Grewal IS, et al. TNF-related apoptosis-inducing ligand (TRAIL)/Apo2L suppresses experimental autoimmune encephalomyelitis in mice. Immunol Cell Biol 2005; 83: 511-9.
-
(2005)
Immunol Cell Biol
, vol.83
, pp. 511-519
-
-
Cretney, E.1
McQualter, J.L.2
Kayagaki, N.3
Yagita, H.4
Bernard, C.C.5
Grewal, I.S.6
-
153
-
-
20944446609
-
Neuronal damage in autoimmune neuroinflammation mediated by the death ligand TRAIL
-
Aktas O, Smorodchenko A, Brocke S, Infante-Duarte C, Schulze Topphoff U, Vogt J, et al. Neuronal damage in autoimmune neuroinflammation mediated by the death ligand TRAIL. Neuron 2005; 46: 421-32.
-
(2005)
Neuron
, vol.46
, pp. 421-432
-
-
Aktas, O.1
Smorodchenko, A.2
Brocke, S.3
Infante-Duarte, C.4
Schulze Topphoff, U.5
Vogt, J.6
-
154
-
-
0034599757
-
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an inhibitor of autoimmune inflammation and cell cycle progression
-
Song K, Chen Y, Goke R, Wilmen A, Seidel C, Goke A, et al. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an inhibitor of autoimmune inflammation and cell cycle progression. J Exp Med 2000; 191: 1095-104.
-
(2000)
J Exp Med
, vol.191
, pp. 1095-1104
-
-
Song, K.1
Chen, Y.2
Goke, R.3
Wilmen, A.4
Seidel, C.5
Goke, A.6
-
155
-
-
3543012048
-
Osteoprotegerin (OPG) acts as an endogenous decoy receptor in tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis of fibroblast-like synovial cells
-
Miyashita T, Kawakami A, Nakashima T, Yamasaki S, Tamai M, Tanaka F, et al. Osteoprotegerin (OPG) acts as an endogenous decoy receptor in tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis of fibroblast-like synovial cells. Clin Exp Immunol 2004; 137: 430-6.
-
(2004)
Clin Exp Immunol
, vol.137
, pp. 430-436
-
-
Miyashita, T.1
Kawakami, A.2
Nakashima, T.3
Yamasaki, S.4
Tamai, M.5
Tanaka, F.6
-
156
-
-
4444371352
-
Rheumatoid arthritis synovial fluid fibroblasts express TRAIL-R2 (DR5) that is functionally active
-
Miranda-Carus ME, Balsa A, Benito-Miguel M, De Ayala CP, Martin-Mola E. Rheumatoid arthritis synovial fluid fibroblasts express TRAIL-R2 (DR5) that is functionally active. Arthritis Rheum 2004; 50: 2786-93.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 2786-2793
-
-
Miranda-Carus, M.E.1
Balsa, A.2
Benito-Miguel, M.3
de Ayala, C.P.4
Martin-Mola, E.5
-
157
-
-
18144416502
-
Tumor necrosis factorrelated apoptosis-inducing ligand (TRAIL) induces rheumatoid arthritis synovial fibroblast proliferation through mitogen-activated protein kinases and phosphatidylinositol 3-kinase/Akt
-
Morel J, Audo R, Hahne M, Combe B. Tumor necrosis factorrelated apoptosis-inducing ligand (TRAIL) induces rheumatoid arthritis synovial fibroblast proliferation through mitogen-activated protein kinases and phosphatidylinositol 3-kinase/Akt. J Biol Chem 2005; 280: 15709-18.
-
(2005)
J Biol Chem
, vol.280
, pp. 15709-18
-
-
Morel, J.1
Audo, R.2
Hahne, M.3
Combe, B.4
-
158
-
-
0037771278
-
TRAIL-R2 (DR5) mediates apoptosis of synovial fibroblasts in rheumatoid arthritis
-
Ichikawa K, Liu W, Fleck M, Zhang H, Zhao L, Ohtsuka T, et al. TRAIL-R2 (DR5) mediates apoptosis of synovial fibroblasts in rheumatoid arthritis. J Immunol 2003; 171: 1061-9.
-
(2003)
J Immunol
, vol.171
, pp. 1061-1069
-
-
Ichikawa, K.1
Liu, W.2
Fleck, M.3
Zhang, H.4
Zhao, L.5
Ohtsuka, T.6
-
159
-
-
0242579588
-
Rheumatoid arthritis synovial fluid macrophages express decreased tumor necrosis factor-related apoptosis-inducing ligand R2 and increased decoy receptor tumor necrosis factor-related apoptosisinducing ligand R3
-
Perlman H, Nguyen N, Liu H, Eslick J, Esser S, Walsh K, et al. Rheumatoid arthritis synovial fluid macrophages express decreased tumor necrosis factor-related apoptosis-inducing ligand R2 and increased decoy receptor tumor necrosis factor-related apoptosisinducing ligand R3. Arthritis Rheum 2003; 48: 3096-101.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 3096-3101
-
-
Perlman, H.1
Nguyen, N.2
Liu, H.3
Eslick, J.4
Esser, S.5
Walsh, K.6
-
160
-
-
0035871631
-
Impaired Fas signaling pathway is involved in defective T cell apoptosis in autoimmune murine arthritis
-
Zhang J, Bardos T, Mikecz K, Finnegan A, Glant TT. Impaired Fas signaling pathway is involved in defective T cell apoptosis in autoimmune murine arthritis. J Immunol 2001; 166: 4981-6.
-
(2001)
J Immunol
, vol.166
, pp. 4981-4986
-
-
Zhang, J.1
Bardos, T.2
Mikecz, K.3
Finnegan, A.4
Glant, T.T.5
-
161
-
-
33845910082
-
Rheumatoid synovial fluid T cells are sensitive to APO2L/TRAIL
-
Martinez-Lorenzo MJ, Anel A, Saez-Gutierrez B, Royo-Canas M, Bosque A, Alava MA, et al. Rheumatoid synovial fluid T cells are sensitive to APO2L/TRAIL. Clin Immunol 2007; 122: 28-40.
-
(2007)
Clin Immunol
, vol.122
, pp. 28-40
-
-
Martinez-Lorenzo, M.J.1
Anel, A.2
Saez-Gutierrez, B.3
Royo-Canas, M.4
Bosque, A.5
Alava, M.A.6
-
162
-
-
19544390527
-
Soluble TRAIL concentrations are raised in patients with systemic lupus erythematosus
-
Lub-de Hooge MN, de Vries EG, de Jong S, Bijl M. Soluble TRAIL concentrations are raised in patients with systemic lupus erythematosus. Ann Rheum Dis 2005; 64: 854-8.
-
(2005)
Ann Rheum Dis
, vol.64
, pp. 854-858
-
-
Lub-de Hooge, M.N.1
de Vries, E.G.2
de Jong, S.3
Bijl, M.4
-
163
-
-
0034633769
-
Apoptosis mediators fasL and TRAIL are upregulated in peripheral blood mononuclear cells in MS
-
Huang WX, Huang MP, Gomes MA, Hillert J. Apoptosis mediators fasL and TRAIL are upregulated in peripheral blood mononuclear cells in MS. Neurology 2000; 55: 928-34.
-
(2000)
Neurology
, vol.55
, pp. 928-934
-
-
Huang, W.X.1
Huang, M.P.2
Gomes, M.A.3
Hillert, J.4
-
164
-
-
12444304354
-
TNF-related apoptosis inducing ligand (TRAIL) as a potential response marker for interferon-beta treatment in multiple sclerosis
-
Wandinger KP, Lunemann JD, Wengert O, Bellmann-Strobl J, Aktas O, Weber A, et al. TNF-related apoptosis inducing ligand (TRAIL) as a potential response marker for interferon-beta treatment in multiple sclerosis. Lancet 2003; 361: 2036-43.
-
(2003)
Lancet
, vol.361
, pp. 2036-2043
-
-
Wandinger, K.P.1
Lunemann, J.D.2
Wengert, O.3
Bellmann-Strobl, J.4
Aktas, O.5
Weber, A.6
-
166
-
-
35448988455
-
TRAIL, CXCL10 and CCL2 plasma levels during long-term Interferon-beta treatment of patients with multiple sclerosis correlate with flu-like adverse effects but do not predict therapeutic response
-
Buttmann M, Merzyn C, Hofstetter HH, Rieckmann P. TRAIL, CXCL10 and CCL2 plasma levels during long-term Interferon-beta treatment of patients with multiple sclerosis correlate with flu-like adverse effects but do not predict therapeutic response. J Neuroimmunol 2007; 190: 170-6.
-
(2007)
J Neuroimmunol
, vol.190
, pp. 170-176
-
-
Buttmann, M.1
Merzyn, C.2
Hofstetter, H.H.3
Rieckmann, P.4
-
167
-
-
84859492848
-
Effects of IFN-B on TRAIL and decoy receptor expression in different immune cell populations from ms patients with distinct disease subtypes
-
485752
-
Hebb AL, Moore CS, Bhan V, Robertson GS. Effects of IFN-B on TRAIL and decoy receptor expression in different immune cell populations from ms patients with distinct disease subtypes. Autoimmune Dis 2010; 2011: 485752.
-
(2010)
Autoimmune Dis
, pp. 2011
-
-
Hebb, A.L.1
Moore, C.S.2
Bhan, V.3
Robertson, G.S.4
-
168
-
-
80052855658
-
-
WO9936535
-
Ashkenazi, A.J., Kelley, R.F., O'Connel, M.T., Pitti, R.M., Schwall, R.H. APO-2 Ligand. WO9936535 (1999).
-
(1999)
APO-2 Ligand
-
-
Ashkenazi, A.J.1
Kelley, R.F.2
O'Connel, M.T.3
Pitti, R.M.4
Schwall, R.H.5
-
169
-
-
33847101622
-
-
WO03042344
-
Flores, H., Lin, T.P., Pai, R., Matthews, T.C., Shahrokh, Z. APO2 Ligand/TRAIL formulations. WO03042344 (2003).
-
(2003)
APO2 Ligand/TRAIL Formulations
-
-
Flores, H.1
Lin, T.P.2
Pai, R.3
Matthews, T.C.4
Shahrokh, Z.5
-
172
-
-
80052852911
-
-
WO0073349
-
Ashkenazi, A.J., Chuntharapai, A., Dodge, K.H., Kim, K.J. DR4 Antibodies and uses thereof. WO0073349 (2000).
-
(2000)
DR4 Antibodies and Uses Thereof
-
-
Ashkenazi, A.J.1
Chuntharapai, A.2
Dodge, K.H.3
Kim, K.J.4
-
176
-
-
80052866223
-
-
WO2005082934
-
Wang, Y., Collins, A.L.T., Hestir, K., Lee, E., Halenbeck, R.F., Bosch, E., Linnermann, T., Williams, L. T. Novel APO2L and IL-24 polypeptides, polynucleotides, and methods of their use. WO2005082934 (2005).
-
(2005)
Novel APO2L and IL-24 Polypeptides, Polynucleotides, and Methods of their Use
-
-
Wang, Y.1
Collins, A.L.T.2
Hestir, K.3
Lee, E.4
Halenbeck, R.F.5
Bosch, E.6
Linnermann, T.7
Williams, L.T.8
-
179
-
-
13544259967
-
Prevention of experimental autoimmune encephalomyelitis by transfer of embryonic stem cell-derived dendritic cells expressing myelin oligodendrocyte glycoprotein peptide along with TRAIL or programmed death-1 ligand
-
Hirata S, Senju S, Matsuyoshi H, Fukuma D, Uemura Y, Nishimura Y. Prevention of experimental autoimmune encephalomyelitis by transfer of embryonic stem cell-derived dendritic cells expressing myelin oligodendrocyte glycoprotein peptide along with TRAIL or programmed death-1 ligand. J Immunol 2005; 174: 1888-97.
-
(2005)
J Immunol
, vol.174
, pp. 1888-1897
-
-
Hirata, S.1
Senju, S.2
Matsuyoshi, H.3
Fukuma, D.4
Uemura, Y.5
Nishimura, Y.6
-
180
-
-
59649094164
-
Fn14-TRAIL, a chimeric intercellular signal exchanger, attenuates experimental autoimmune encephalomyelitis
-
Razmara M, Hilliard B, Ziarani AK, Murali R, Yellayi S, Ghazanfar M, et al. Fn14-TRAIL, a chimeric intercellular signal exchanger, attenuates experimental autoimmune encephalomyelitis. Am J Pathol 2009; 174: 460-74.
-
(2009)
Am J Pathol
, vol.174
, pp. 460-474
-
-
Razmara, M.1
Hilliard, B.2
Ziarani, A.K.3
Murali, R.4
Yellayi, S.5
Ghazanfar, M.6
-
183
-
-
0037670222
-
Intra-articular adenoviral-mediated gene transfer of trail induces apoptosis of arthritic rabbit synovium
-
Yao Q, Wang S, Gambotto A, Glorioso JC, Evans CH, Robbins PD, et al. Intra-articular adenoviral-mediated gene transfer of trail induces apoptosis of arthritic rabbit synovium. Gene Ther 2003; 10: 1055-60.
-
(2003)
Gene Ther
, vol.10
, pp. 1055-1060
-
-
Yao, Q.1
Wang, S.2
Gambotto, A.3
Glorioso, J.C.4
Evans, C.H.5
Robbins, P.D.6
-
184
-
-
34347237670
-
Concurrent gene therapy strategies effectively destroy synoviocytes of patients with rheumatoid arthritis
-
Terzioglu E, Bisgin A, Sanlioglu AD, Ulker M, Yazisiz V, Tuzuner S, et al. Concurrent gene therapy strategies effectively destroy synoviocytes of patients with rheumatoid arthritis. Rheumatology (Oxford) 2007; 46: 783-9.
-
(2007)
Rheumatology (Oxford)
, vol.46
, pp. 783-789
-
-
Terzioglu, E.1
Bisgin, A.2
Sanlioglu, A.D.3
Ulker, M.4
Yazisiz, V.5
Tuzuner, S.6
-
185
-
-
70350489381
-
Intra-articular injection of recombinant TRAIL induces synovial apoptosis and reduces inflammation in a rabbit knee model of arthritis
-
Yao Q, Seol DW, Mi Z, Robbins PD. Intra-articular injection of recombinant TRAIL induces synovial apoptosis and reduces inflammation in a rabbit knee model of arthritis. Arthritis Res Ther 2006; 8: R16.
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Yao, Q.1
Seol, D.W.2
Mi, Z.3
Robbins, P.D.4
-
186
-
-
77249126595
-
Effect of tumor necrosis factor-related apoptosis-inducing ligand on the reduction of joint inflammation in experimental rheumatoid arthritis
-
Jin CH, Chae SY, Kim TH, Yang HK, Lee EY, Song YW, et al. Effect of tumor necrosis factor-related apoptosis-inducing ligand on the reduction of joint inflammation in experimental rheumatoid arthritis. J Pharmacol Exp Ther 2010; 332: 858-65.
-
(2010)
J Pharmacol Exp Ther
, vol.332
, pp. 858-865
-
-
Jin, C.H.1
Chae, S.Y.2
Kim, T.H.3
Yang, H.K.4
Lee, E.Y.5
Song, Y.W.6
-
187
-
-
0842308921
-
Actinomycin D renders cultured synovial fibroblasts susceptible to tumour necrosis factor related apoptosis-inducing ligand (TRAIL)-induced apoptosis
-
Park YW, Ji JD, Lee JS, Ryang DW, Yoo DH. Actinomycin D renders cultured synovial fibroblasts susceptible to tumour necrosis factor related apoptosis-inducing ligand (TRAIL)-induced apoptosis. Scand J Rheumatol 2003; 32: 356-63.
-
(2003)
Scand J Rheumatol
, vol.32
, pp. 356-363
-
-
Park, Y.W.1
Ji, J.D.2
Lee, J.S.3
Ryang, D.W.4
Yoo, D.H.5
-
188
-
-
69049110871
-
The pleiotropic effect of TRAIL on tumor-like synovial fibroblasts from rheumatoid arthritis patients is mediated by caspases
-
Audo R, Combe B, Coulet B, Morel J, Hahne M. The pleiotropic effect of TRAIL on tumor-like synovial fibroblasts from rheumatoid arthritis patients is mediated by caspases. Cell Death Differ 2009; 16(9):1227-37.
-
(2009)
Cell Death Differ
, vol.16
, Issue.9
, pp. 1227-1237
-
-
Audo, R.1
Combe, B.2
Coulet, B.3
Morel, J.4
Hahne, M.5
-
189
-
-
62849096248
-
Susceptibility of rheumatoid arthritis synovial fibroblasts to FasL-and TRAIL-induced apoptosis is cell cycledependent
-
Pundt N, Peters MA, Wunrau C, Strietholt S, Fehrmann C, Neugebauer K, et al. Susceptibility of rheumatoid arthritis synovial fibroblasts to FasL-and TRAIL-induced apoptosis is cell cycledependent. Arthritis Res Ther 2009; 11: R16.
-
(2009)
Arthritis Res Ther
, vol.11
-
-
Pundt, N.1
Peters, M.A.2
Wunrau, C.3
Strietholt, S.4
Fehrmann, C.5
Neugebauer, K.6
-
190
-
-
79953678970
-
Mechanisms and clinical relevance of TRAIL-triggered responses in synovial fibroblasts of rheumatoid arthritis patients
-
Audo R, Calmon-Hamaty F, Baeten D, Bruyer A, Combe B, Hahne M, et al. Mechanisms and clinical relevance of TRAIL-triggered responses in synovial fibroblasts of rheumatoid arthritis patients. Arthritis Rheum 2011; 63(4):904-13.
-
(2011)
Arthritis Rheum
, vol.63
, Issue.4
, pp. 904-913
-
-
Audo, R.1
Calmon-Hamaty, F.2
Baeten, D.3
Bruyer, A.4
Combe, B.5
Hahne, M.6
-
191
-
-
0346969979
-
CII-DCAdTRAIL cell gene therapy inhibits infiltration of CII-reactive T cells and CII-induced arthritis
-
Liu Z, Xu X, Hsu HC, Tousson A, Yang PA, Wu Q, et al. CII-DCAdTRAIL cell gene therapy inhibits infiltration of CII-reactive T cells and CII-induced arthritis. J Clin Invest 2003; 112: 1332-41.
-
(2003)
J Clin Invest
, vol.112
, pp. 1332-1341
-
-
Liu, Z.1
Xu, X.2
Hsu, H.C.3
Tousson, A.4
Yang, P.A.5
Wu, Q.6
-
192
-
-
72449177989
-
Anti-DR5 mAb ameliorate adjuvant arthritis rats through inducing synovial cells apoptosis
-
Li W, Liu Z, Zhuang G, Yin P, Tao H, Qiu J, et al. Anti-DR5 mAb ameliorate adjuvant arthritis rats through inducing synovial cells apoptosis. Exp Biol Med (Maywood) 2009; 234: 1468-76.
-
(2009)
Exp Biol Med (Maywood)
, vol.234
, pp. 1468-1476
-
-
Li, W.1
Liu, Z.2
Zhuang, G.3
Yin, P.4
Tao, H.5
Qiu, J.6
-
193
-
-
80052842223
-
-
WO2007145457
-
Lee, K.G., Chae, S.Y., Youn, Y.S., Kim, W.B., Lee, S.K. NTerminal modified PEG-TRAIL, Method for preparing and uses thereof. WO2007145457 (2007).
-
(2007)
NTerminal Modified PEG-TRAIL, Method For Preparing and Uses Thereof
-
-
Lee, K.G.1
Chae, S.Y.2
Youn, Y.S.3
Kim, W.B.4
Lee, S.K.5
-
194
-
-
84860225893
-
-
WO2011020933
-
Anel Bernal, L.A., Martínez Lorenzo, M.J., Martínez Lostao, L., Álava de Contrasta, M.A., Larrad Mur, L., Naval Iraberri, J., Piñeiro Antón, A. Basáñez Asúa, G. Liposome covered with the extracellular domain of APO2L/TRAIL protein. WO2011020933 (2011).
-
(2011)
Liposome Covered With the Extracellular Domain of APO2L/TRAIL Protein
-
-
Anel Bernal, L.A.1
Martínez Lorenzo, M.J.2
Martínez Lostao, L.3
Álava de Contrasta, M.A.4
Larrad Mur, L.5
Naval Iraberri, J.6
Piñeiro Antón, A.7
Basáñez Asúa, G.8
-
195
-
-
77957313563
-
Ionic complex systems based on hyaluronic acid and PEGylated TNF-related apoptosis-inducing ligand for treatment of rheumatoid arthritis
-
Kim YJ, Chae SY, Jin CH, Sivasubramanian M, Son S, Choi KY, et al. Ionic complex systems based on hyaluronic acid and PEGylated TNF-related apoptosis-inducing ligand for treatment of rheumatoid arthritis. Biomaterials 2010; 31: 9057-64.
-
(2010)
Biomaterials
, vol.31
, pp. 9057-9064
-
-
Kim, Y.J.1
Chae, S.Y.2
Jin, C.H.3
Sivasubramanian, M.4
Son, S.5
Choi, K.Y.6
-
196
-
-
77955409183
-
Liposome-bound APO2L/TRAIL is an effective treatment in a rheumatoid arthritis model
-
Martinez-Lostao L, Garcia-Alvarez F, Basanez G, Alegre-Aguaron E, Desportes P, Larrad L, et al. Liposome-bound APO2L/TRAIL is an effective treatment in a rheumatoid arthritis model. Arthritis Rheum 2010; 62: 2272-82.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 2272-2282
-
-
Martinez-Lostao, L.1
Garcia-Alvarez, F.2
Basanez, G.3
Alegre-Aguaron, E.4
Desportes, P.5
Larrad, L.6
|