Molecular Mechanisms for Cardiovascular Stem Cell Apoptosis and Growth in the Hearts with Atherosclerotic Coronary Disease and Ischemic Heart Failure

Annals of the New York Academy of Sciences

Volumn 1010, Issue , 2003, Pages 687-697

  Geng, Yong Jian ^a,b  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

Apoptosis; Atherosclerosis; Heart failure; Myocytes; Stem cells

Indexed keywords

CYTOKINE; CYTOTOXIC FACTOR; GROWTH FACTOR; NUCLEAR PROTEIN; PROTEINASE; TELOMERASE;

ANIMAL TISSUE; APOPTOSIS; CELL DIFFERENTIATION; CELL GROWTH; CELL INTERACTION; CELL REGENERATION; CONFERENCE PAPER; CORONARY ARTERY ATHEROSCLEROSIS; EMBRYO; ENVIRONMENTAL FACTOR; ENZYME ACTIVITY; HEART FAILURE; HEART MUSCLE CELL; HOST CELL; LIFESPAN; MITOCHONDRIAL RESPIRATION; MOLECULAR MECHANICS; MORPHOGENESIS; NONHUMAN; STEM CELL; TISSUE REPAIR;

ANIMALIA;

EID: 1342284231     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1299.126     Document Type: Conference Paper

References (30)

1. GENG, Y.J. 1997. Regulation of programmed cell death or apoptosis in atherosclerosis. Heart Vessels Suppl. 12: 76-80.
2. GENG, Y.J. 2001. Molecular signal transduction in vascular cell apoptosis. Cell Res. 11: 253-64.
3. GENG, Y.J. 2001. Biologic effect and molecular regulation of vascular apoptosis in atherosclerosis. Curr. Atheroscler. Rep. 3: 234-242.
4. GENG, Y.J. & P. LIBBY. 2002. Progression of atheroma: a struggle between death and procreation. Arterioscler. Thromb. Vasc. Biol. 22: 1370-1380.
5. BISHOPRIC, N.H., P. ANDREKA, T. SLEPAK & K.A. WEBSTER. 2001. Molecular mechanisms of apoptosis in the cardiac myocyte. Curr. Opin. Pharmacol. 1: 141-150.
6. DISPERSYN, G.D. & M. BORGERS. 2001. Apoptosis in the heart: about programmed cell death and survival. News Physiol. Sci. 16: 41-47.
7. PAULUS, W.J. 2001. The role of nitric oxide in the failing heart. Heart Fail Rev. 6: 105-118.
8. GENG, Y.J. & P. LIBBY. 1995. Evidence for apoptosis in advanced human atheroma. Colocalization with interleukin-1 beta-converting enzyme. Am. J. Pathol. 147: 251-266.
9. GENG, Y.J., Q. WU, M. MUSZYNSKI, et al. 1996. Apoptosis of vascular smooth muscle cells induced by in vitro stimulation with interferon-gamma, tumor necrosis factor-alpha, and interleukin-1 beta. Arterioscler. Thromb. Vasc. Biol. 16: 19-27.
10. GENG, Y.J., L.E. HENDERSON, E.B. LEVESQUE, et al. 1997. Fas is expressed in human atherosclerotic intima and promotes apoptosis of cytokine-primed human vascular smooth muscle cells. Arterioscler. Thromb. Vasc. Biol. 17: 2200-2208.
11. GENG, Y.J., T. AZUMA, J.X. TANG, et al. 1998. Caspase-3-induced gelsolin fragmentation contributes to actin cytoskeletal collapse, nucleolysis, and apoptosis of vascular smooth muscle cells exposed to proinflammatory cytokines. Eur. J. Cell Biol. 77: 294-302.
12. GENG, Y.J., Y. ISHIKAWA, D.E. VATNER, et al. 1999. Apoptosis of cardiac myocytes in Gsalpha transgenic mice. Circ. Res. 84: 34-42.
13. HUGHES, S. 2002. Cardiac stem cells. J. Pathol. 197: 468-478.
14. MENASCHE, P. 2002. Cellular transplantation for the treatment of heart failure. Ernst Schering Res. Found. Workshop: 67-72.
15. TAYLOR, D.A. 2001. Cellular cardiomyoplasty with autologous skeletal myoblasts for ischemic heart disease and heart failure. Curr. Control Trials Cardiovasc. Med. 2: 208-210.
16. MULLER-EHMSEN, J., L.H. KEDES, R.H. SCHWINGER & R.A. KLONER. 2002. Cellular cardiomyoplasty - a novel approach to treat heart disease. Congest. Heart Fail. 8: 220-227.
17. MENASCHE, P. 2002. Cell transplantation for the treatment of heart failure. Semin. Thorac. Cardiovasc. Surg. 14: 157-166.
18. ANVERSA, P., A. LERI, J. KAJSTURA & B. NADAL-GINARD. 2002. Myocyte growth and cardiac repair. J. Mol. Cell. Cardiol. 34: 91-105.
19. MULLER-EHMSEN, J., P. WHITTAKER, R.A. KLONER, et al. 2002. Survival and development of neonatal rat cardiomyocytes transplanted into adult myocardium. J. Mol. Cell. Cardiol. 34: 107-116.
20. GREEN, D.R. & T.A. FERGUSON. 2001. The role of Fas ligand in immune privilege. Nat. Rev. Mol. Cell Biol. 2: 917-924.
21. LI, J.H., D. ROSEN, P. SONDEL & G. BERKE. 2002. Immune privilege and FasL: two ways to inactivate effector cytotoxic T lymphocytes by FasL-expressing cells. Immunology 105: 267-277.
22. SAITO, T., J.Q. KUANG, B. BITTIRA, et al. 2002. Xenotransplant cardiac chimera: immune tolerance of adult stem cells. Ann. Thorac. Surg. 74: 19-24; discussion 24.
23. DRAB, M., H. HALLER, R. BYCHKOV, et al. 1997. From totipotent embryonic stem cells to spontaneously contracting smooth muscle cells: a retinoic acid and db-cAMP in vitro differentiation model. FASEB J. 11: 905-915.
24. XU, C., G. LIGUORI, M.G. PERSICO & E.D. ADAMSON. 1999. Abrogation of the Cripto gene in mouse leads to failure of postgastrulation morphogenesis and lack of differentiation of cardiomyocytes. Development 126: 483-494.
25. HUH, N.E., K.B. PASUMARTHI, M.H. SOONPAA, et al. 2001. Functional abrogation of p53 is required for T-Ag induced proliferation in cardiomyocytes. J. Mol. Cell. Cardiol. 233: 1405-1419.
26. PASUMARTHI, K.B., S.C. TSAI & L.J. FIELD. 2001. Coexpression of mutant p53 and p 193 renders embryonic stem cell-derived cardiomyocytes responsive to the growth-promoting activities of adenoviral E1A. Circ. Res. 88: 1004-1011.
27. TRAN, C.M. & H.M. Sucov. 1988. The RXRalpha gene functions in a non-cell-autonomous manner during mouse cardiac morphogenesis. Development 125: 1951-1956.
28. 2 homeostasis by hypoxia-inducible factor 1 alpha. Genes Dev. 12: 149-162.
29. ADELMAN, D.M. & M.C. SIMON. 2002. Hypoxic gene regulation in differentiating ES cells. Methods Mol. Biol. 185: 55-62.
30. WU, H., S.H. LEE, J. GAO, et al. 1999. Inactivation of erythropoietin leads to defects in cardiac morphogenesis. Development 126: 3597-3605.