Sirtuin 1 overexpression mice show a reference memory deficit, but not neuroprotection

Biochemical and Biophysical Research Communications

Volumn 387, Issue 4, 2009, Pages 784-788

  Kakefuda, Kenichi ^a   Fujita, Yasunori ^b   Oyagi, Atsushi ^a   Hyakkoku, Kana ^a   Kojima, Toshio ^c   Umemura, Ken ^b   Tsuruma, Kazuhiro ^a   Shimazawa, Masamitsu ^a   Ito, Masafumi ^b   Nozawa, Yoshinori ^b   Hara, Hideaki ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b GIFU INTERNATIONAL INSTITUTE OF BIOTECHNOLOGY   (Japan)

^c RIKEN   (Japan)

Author keywords

Cognitive function; Ischemia; MPTP; SIRT1; Transgenic model

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; NEURON SPECIFIC ENOLASE; SIRTUIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; BRAIN ISCHEMIA; CONTROLLED STUDY; DEGENERATIVE DISEASE; IN VIVO STUDY; LIFESPAN; MEMORY DISORDER; MOUSE; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; BRAIN ISCHEMIA; MEMORY DISORDERS; MICE; MICE, TRANSGENIC; NEURODEGENERATIVE DISEASES; NEURONS; NEUROTOXINS; SIRTUINS;

MAMMALIA; MUS;

EID: 68549085061     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.07.119     Document Type: Article

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