Reactive metabolites and AGE/RAGE-mediated cellular dysfunction affect the aging process - A mini-review

Gerontology

Volumn 57, Issue 5, 2011, Pages 435-443

  Fleming, Thomas H ^a   Humpert, Per M ^a   Nawroth, Peter P ^a   Bierhaus, Angelika ^a,b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b Department of Medicine I and Clinical Chemistry ^*  (Germany)

Author keywords

Advanced glycation endproduct receptor; Advanced glycation endproducts; Methylglyoxal

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; CARBOHYDRATE DERIVATIVE; CARBONYL DERIVATIVE; GLUCOSE; GLUTATHIONE; GLYOXAL; GLYOXALASE; HISTONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; METHYLGLYOXAL; REACTIVE CARBONYL SPECIES; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TRIOSEPHOSPHATE ISOMERASE; UNCLASSIFIED DRUG;

ACETYLATION; AGING; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; CALORIC RESTRICTION; CELL STRESS; CHRONIC KIDNEY DISEASE; DEGENERATIVE DISEASE; DEGRADATION; DETOXIFICATION; DISEASE COURSE; EMBRYO DEVELOPMENT; EPIGENETICS; EXPERIMENTAL MODEL; GENE; GENE EXPRESSION; GLYCATION; HISTONE UBIQUITINATION; HUMAN; INTRACELLULAR SIGNALING; METHYLATION; MUSCULOSKELETAL DISEASE; NONHUMAN; PHARMACEUTICAL CARE; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN GLYCOSYLATION; REVIEW; VASCULAR DISEASE;

AGE FACTORS; AGED; AGING; BIOTRANSFORMATION; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; INFLAMMATION MEDIATORS; LACTOYLGLUTATHIONE LYASE; LONGEVITY; METABOLIC NETWORKS AND PATHWAYS; NF-KAPPA B;

EID: 80052505427     PISSN: 0304324X     EISSN: 14230003     Source Type: Journal    
DOI: 10.1159/000322087     Document Type: Review

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