Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans

Aging Cell

Volumn 7, Issue 2, 2008, Pages 260-269

  Morcos, Michael ^a   Du, Xueliang ^b   Pfisterer, Friederike ^a   Hutter, Harald ^c   Sayed, Ahmed A R ^a   Thornalley, Paul ^d   Ahmed, Naila ^d   Baynes, John ^e   Thorpe, Suzanne ^e   Kukudov, Georgi ^a   Schlotterer, Andreas ^a   Bozorgmehr, Farastuk ^a   El Baki, Randa Abd ^a   Stern, David ^f   Moehrlen, Frank ^a   Ibrahim, Youssef ^a   Oikonomou, Dimitrios ^a   Hamann, Andreas ^a   Becker, Christian ^a   Zeier, Martin ^a   Schwenger, Vedat ^a   Miftari, Nexhat ^a   Humpert, Per ^a   Hammes, Hans Peter ^g   Buechler, Markus ^a   Bierhaus, Angelika ^a   Brownlee, Michael ^b   Nawroth, Peter P ^a   more..

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

^d UNIVERSITY OF ESSEX   (United Kingdom)

^e UNIVERSITY OF SOUTH CAROLINA   (United States)

^f UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^g UNIVERSITY OF MANNHEIM   (Germany)

Author keywords

Advanced Glycation Endproducts; Aging; C. elegans; Glyoxalase 1; Lifespan; Metabolicrate; Mitochondria; Reactive oxygen species

Indexed keywords

CAENORHABDITIS ELEGANS PROTEIN; LACTOYLGLUTATHIONE LYASE; MESSENGER RNA; METHYLGLYOXAL; MITOCHONDRIAL PROTEIN; REACTIVE OXYGEN METABOLITE;

ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE OVEREXPRESSION; GLYCOLYSIS; LIFESPAN; MOLECULAR MECHANICS; NONHUMAN; ORTHOLOGY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; ENZYME INHIBITORS; FEEDBACK, BIOCHEMICAL; GENE EXPRESSION; LACTOYLGLUTATHIONE LYASE; LONGEVITY; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MUTATION; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PROTEIN MODIFICATION, TRANSLATIONAL; PYRUVALDEHYDE; REACTIVE OXYGEN SPECIES; RNA, HELMINTH; RNA, MESSENGER;

CAENORHABDITIS ELEGANS;

EID: 40549129694     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2008.00371.x     Document Type: Article

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