Increased dicarbonyl metabolism in endothelial cells in hyperglycemia induces anoikis and impairs angiogenesis by RGD and GFOGER motif modification

Diabetes

Volumn 55, Issue 7, 2006, Pages 1961-1969

  Dobler, Darin ^a   Ahmed, Naila ^a   Song, Lijiang ^a   Eboigbodin, Kevin E ^a   Thornalley, Paul J ^a  

^a UNIVERSITY OF ESSEX   (United Kingdom)

Author keywords

AGE, advanced glycation end product; AGEmin collagen, collagen modified minimally by glucose derived AGEs; BrBzGSHCp2, S p bromobenzylglutathione cyclopentyl diester; ECM, extracellular matrix; HAEC, human aortic endothelial cell

Indexed keywords

ARGININE; COLLAGEN TYPE 4; METHYLGLYOXAL; ARGINYL-GLYCYL-ASPARTIC ACID; ARGINYLGLYCYLASPARTIC ACID; OLIGOPEPTIDE;

ANGIOGENESIS; ANOIKIS; ARTICLE; BINDING SITE; CELL ADHESION; CELL VIABILITY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HYPERGLYCEMIA; IN VITRO STUDY; IN VIVO STUDY; PRIORITY JOURNAL; VASCULARIZATION; AMINO ACID SEQUENCE; CELL LINE; CHEMICAL STRUCTURE; CYTOLOGY; EXTRACELLULAR MATRIX; GLYCOSYLATION; MASS SPECTROMETRY; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); PEPTIDE MAPPING; PHYSIOLOGY; VASCULAR ENDOTHELIUM;

AMINO ACID SEQUENCE; ANOIKIS; CELL ADHESION; CELL LINE; ENDOTHELIUM, VASCULAR; EXTRACELLULAR MATRIX; GLYCOSYLATION; HUMANS; HYPERGLYCEMIA; MASS SPECTROMETRY; MODELS, MOLECULAR; NEOVASCULARIZATION, PATHOLOGIC; NEOVASCULARIZATION, PHYSIOLOGIC; OLIGOPEPTIDES; PEPTIDE MAPPING;

EID: 33747080843     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db05-1634     Document Type: Article

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