Cross talk between activation of microglia and astrocytes in pathological conditions in the central nervous system

Life Sciences

Volumn 89, Issue 5-6, 2011, Pages 141-146

  Liu, W ^a   Tang, Y ^b   Feng, J ^c  

^a GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

Activation; Astrocyte; ATP; Cross talk; IL 1; Microglia; TGF

Indexed keywords

ADENOSINE TRIPHOSPHATE; CONNEXIN 43; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 18; INTERLEUKIN 1BETA; NERVE GROWTH FACTOR; NITRIC OXIDE; OXYGEN RADICAL; PHOSPHOLIPASE C; PROSTAGLANDIN D2; PURINERGIC RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; TRIMETHYLTIN; TUMOR NECROSIS FACTOR ALPHA;

ALZHEIMER DISEASE; ANTIGEN PRESENTATION; ASTROCYTE; B LYMPHOCYTE; BRAIN DAMAGE; BRAIN ISCHEMIA; CALCIUM BINDING; CALCIUM CELL LEVEL; CELL ACTIVATION; CELL ACTIVITY; CELL MIGRATION; CELL PROLIFERATION; CELL REGENERATION; CENTRAL NERVOUS SYSTEM; CHEMOTAXIS; DEGENERATIVE DISEASE; DOWN REGULATION; ENZYME INHIBITION; GAP JUNCTION; MAJOR HISTOCOMPATIBILITY COMPLEX; MICROGLIA; MOLECULAR INTERACTION; NERVE FIBER; NEUROPATHIC PAIN; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PHAGOCYTOSIS; PHOSPHORYLATION; PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION; SPINAL CORD DORSAL HORN; SPINAL NERVE; T LYMPHOCYTE; UPREGULATION;

EID: 80051782344     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2011.05.011     Document Type: Review

References (82)

1. Albrecht PJ, Dahl JP, Stoltzfus OK, Levenson R, Levison SW. Ciliary neurotrophic factor activates spinal cord astrocytes, stimulating their production and release of fibroblast growth factor-2, to increase motor neuron survival. Exp Neurol 2002;173(1): 46-62. (Pubitemid 34081725)
2. Balasingam V, Tejada-Berges T, Wright E, Bouckova R, Yong VW. Reactive astrogliosis in the neonatal mouse brain and its modulation by cytokines. J Neurosci 1994;14(2): 846-56. (Pubitemid 24043936)
3. Bianco F, Pravettoni E, Colombo A, Schenk U, Moller T, Matteoli M, et al. Astrocytes-derived ATP induces vesicle shedding and IL-1β release from microglia. J Immunol 2005;174(11):7268-77. (Pubitemid 40705696)
4. Blomstrand F, Aberg ND, Eriksson PS, Hasson E, Ronnback L. Extent of intercellular calcium wave propagation is related to gap junction permeability and level of connexin-43 expression in astrocytes in primary cultures from four brain regions. Neuroscience 1999;92(1):255-65. (Pubitemid 29249036)
5. Boucsein C, Zacharias R, Farver K, Pavlovic S, Hanisch UK, Kettenmann H. Purinergic receptors on microglia cells: functional expression in acute brain slices and modulation of microglial activation in vitro. Eur J Neurosci 2003;17(11):2267-76. (Pubitemid 36793736)
6. Boutin H, Lefeuvre RA, Horai R, Asano M, Iwakura Y, Rothwell NJ. Role of IL-1alpha and IL-1beta in ischemic brain damage. J Neurosci 2001;21(15):5528-34. (Pubitemid 32692151)
7. Chao CC, Hu S, Sheng WS, Bu D, Bukrinsky MI, Peterson PK. Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism. Glia 1996;16(3):276-84. (Pubitemid 26309470)
8. Chavarria A, Alcocer-Varela J. Is damage in central nervous system due to inflammation? Autoimmun Rev 2004;3(4):251-60. (Pubitemid 38887620)
9. Chen W, Wahl SM. TGF-beta: receptors, signaling pathways and autoimmunity. Curr Dir Autoimmun 2002;5:62-91.
10. Colburn RW, Deleo JA, Rickman AJ, Yeager MP, Kwon P, Hickey WF. Dissociation of microglial activation and neuropathic pain behaviors following peripheral nerve injury in the rat. J Neuroimmuology 1997;79(2):163-75. (Pubitemid 27502035)
11. Cornell-Bell AH, Finkbeiner SM, Cooper MS, Simth SJ. Glutamate induces calcium waves in cultured astrocytes: long-rang glial signaling. Science 1990;247(494):470-3.
12. Cotrina ML, Lin JH, Alves-Rodrigues A, Liu S, Li J, Azmi-Ghadimi H, et al. Connexins regulate calcium signaling by controlling ATP release. Proc Natl Acad Sci U S A 1998;95:15735-40. (Pubitemid 29018769)
13. da Cunha A, Jefferson JA, Jackson RW, Vitković L. Glial cell-specific mechanisms of TGF-β1 induction by IL-1 in cerebral cortex. J Neuroimmunol 1993;42(1):71-85. (Pubitemid 23025194)
14. Davalos D, Grutzendler J, Yang G, Kim JV, Zuo Y, Jung S, et al. ATP mediates rapid microglial response to local brain injury in vivo. Nat Neurosci 2005;8(6):752-8. (Pubitemid 43085841)
15. Dewitt DA, Perry G, Cohen M, Doller C, Silver J. Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease. Exp Neurol 1998;149(2): 329-40. (Pubitemid 28115071)
16. Escartin C, Bonvento G. Targeted activation of astrocytes: a potential neuroprotective strategy. Mol Neurobiol 2008;38(3):231-41.
17. Fang KM, Yang CS, Sun SH, Tzeng SF. Microglial phagocytosis attenuated by short-term exposure to exogenous ATP through P2X receptor action. J Neurochem 2009;111: 1225-37.
18. Frautschy SA, Yang F, Irizarry M, Hyman B, Saido TC, Hsiao K, et al. Microglial response to amyloid plaques in APPsw transgenic mice. Am J Pathol 1998;152(1):307-17. (Pubitemid 28028071)
19. Gatan E, Overmier BJ. Inflammatory pathogenesis in Alzheimer's disease: biological mechanisms and cognitive sequeli. Neurosci Biobehav Rev 1999;23(5):615-33.
20. Griffin WS. Inflammation and neurodegenerative diseases. Am J Clin Nutr 2006;83(2): 470-4.
21. Guan X, Cravatt BF, Ehring GR, Hall JE, Boger DL, Lerner RA, et al. The sleep-inducing lipid oleamide deconvolutes gap junction communication and calcium wave transmission in glial cells. J Cell Biol 1997;139:1785-92. (Pubitemid 28079242)
22. Guthrie PB, Knappenberger J, Segal M, Beett MV, Charles AC, Kater SB. ATP released from astrocytes mediates glial calcium waves. J Neurosci 1999;19(2):520-8. (Pubitemid 29036003)
23. Hansson E. Could chronic pain and spread of pain sensation be induced and maintained by glial activation? Acta Physiol 2006;187(1-2):321-7. (Pubitemid 43828790)
24. Haydon PG. Glia: listening and talking to the synapse. Nat Rev Neurosci 2001;2(3): 185-93. (Pubitemid 33673371)
25. Haydon PG, Carmignoto G. Astrocytes control of synaptic transmission and neurovas-cular coupling. Physiol Rev 2006;86(3):1009-31. (Pubitemid 44033387)
26. Haynes SE, Hollopeter G, Yang G, Kurpius D, Dailey ME, Gan WB, et al. The P2Y12 receptor regulates microglial activation by extracellular nucleotides. Nat Neurosci 2006;9:1512-9. (Pubitemid 44862659)
27. Herrera-Molina R, von Bernhardi R. Transforming growth factor-beta 1 produced by hippocampal cells modulates microglial reactivity in culture. Neurobiol Dis 2005;19(1-2):229-36. (Pubitemid 40544740)
28. Herx LM, Yong VW. Interleukin-1 beta is required for the early evolution of reactive astrogliosis following CNS lesion. J Neuropathol Exp Neurol 2001;60(10):961-71. (Pubitemid 32924122)
29. Herx LM, Rivest S, Yong VW. Central nervous system-initiated inflammation and neurotrophism in trauma: interleukin-1beta is required for the production of ciliary neurotrophic factor. J Immunol 2000;165(4):2232-9. (Pubitemid 30643173)
30. Hickey WF, Kimura H. Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo. Science 1988;239(4837):290-2. (Pubitemid 18061496)
31. Hide I, Tanaka M, Inoue A, Nakajima K, Kohsaka S, Inoue K, et al. Extracellular ATP triggers tumor necrosis factor-alpha release from rat microglia. J Neurochem 2000;75(3):965-72. (Pubitemid 30660484)
32. Honda S, Sasaki Y, Ohsawa K, Imai Y, Nakamura Y, Inoue K, et al. Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors. J Neurosci 2001;21(6):1975-82. (Pubitemid 32221381)
33. Hu S, Chao CC, Ehrlich LC, Sheng WS, Sutton RL, Rockswold GL, et al. Inhibition of microglial cell RANTES production by IL-10 and TGF-beta. J Leukoc Biol 1999;65(6):815-21. (Pubitemid 29279531)
34. Hu S, Sheng WS, Ehrlich LC, Peterson PK, Chao CC. Cytokine effects on glutamate uptake by human astrocytes. Neuroimmunomodulation 2000;7(3):153-9. (Pubitemid 30204821)
35. Huang WC, Yen FC, Shie FS, Pan CM, Shiao YJ, Yang CN, et al. TGF-beta1 blockade of microglial chemotaxis toward Abeta aggregates involves SMAD signaling and down-regulation of CCL5. J Neuroinflammation 2010;7:28.
36. Inoue K, Nakajima K, Morimoto T, Kikuchi Y, Koizumi S, Illes P, et al. ATP stimulation of Ca2+-dependent plasminogen release from cultured microglia. Br J Pharmacol 1998;123(7):1304-10. (Pubitemid 28143128)
37. Jauneau AC, Ischenko A, Chatagner A, Benard M, Chan P, Schouft MT, et al. Interleukin-1 beta and anaphylatoxins exert a synergistic effect on NGF expression by astrocytes. J Neuroinflammation 2006;3:8.
38. Jing T, Wu L, Borgmann K, Surendran S, Ghorpade A, Liu J, et al. Soluble factors from IL- 1 [Stimulated astrocytes activate NR1a/NR2B receptors: Implications for HIV-1- induced neurodegeneration. Biochem Biophys Res Commun 2010;402(2):241-6.
39. John GR, Chen L, Rivieccio MA, Melendez-Vasquez CV, Hartley A, Brosnan CF. Interleukin-1beta induces a reactive astroglial phenotype via deactivation of the Rho GTPase-Rock axis. J Neurosci 2004;24(11):2837-45. (Pubitemid 38380962)
40. John GR, Lee SC, Song X, Rivieccio M, Brosnan CF. IL-1-regulated responses in astrocytes: relevance to injury and recovery. Glia 2005;49(2):161-76. (Pubitemid 40188496)
41. Kettenmann H, Verkhratsky A. Neuroglia: the 150 years after. Trends Neurosci 2008;31(12): 653-9.
42. KimSU, de Vellis J. Microglia in health and disease. J Neurosci Res 2005;81(3):302-13. (Pubitemid 41359284)
43. Koizumi S, Shigemoto-Mogami Y, Nasu-Tada K, Shinozaki Y, Ohsawa K, Tsuda M, et al. UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis. Nature 2007;446(7139):1091-5. (Pubitemid 46676051)
44. Kreutzberg GW. Microglia: a sensor for pathological events in the CNS. Trends Neurosci 1996;19(8):312-8. (Pubitemid 26349059)
45. Kyrkanides S, Olschowka JA, Williams JP, Hansen JT, O'Banion MK. TNF alpha and IL- 1beta mediate intercellular adhesion molecule-1 induction via microglia-astrocyte interaction in CNS radiation injury. J Neuroimmunol 1999;95(1-2):95-106. (Pubitemid 29173026)
46. Lee JK, Seo EM, Lee SS, Park SH, Sim YB, Jung JS, et al. Activation of PPARa attenuates IFN~y and IL-1p>-induced cell proliferation in astrocytes: involvement of IL-6 independent pathway. Korean J Physiol Pharmacol 2010;14(3):185-9.
47. Lehrmann E, Christensen T, Zimmer J, Diemer H, Finsen B. Microglial and macrophage reactions mark progressive changes and define the penumbra in the rat neocortex and striatum after transient middle cerebral artery occlusion. J Comp Neurol 1997;386(3):461-76. (Pubitemid 27381505)
48. Liu W, Wang CH, Cui Y, Mo LQ, Zhi JL, Sun SN, et al. Inhibition of neuronal nitric oxide synthase antagonizes morphine antinociceptive tolerance by decreasing activation of p38 MAPK in the spinal microglia. Neurosci Lett 2006;410(3):174-7. (Pubitemid 44750337)
49. Matsumoto Y, Ohmori K, Fujiwara M. Microglia and astroglial reactions to inflammatory lesions of experimental autoimmune encephalomyelitis in the rat central nervous system. J Neuroimmunol 1992;37(1-2):23-33.
50. McCann MG, O'Callaghan JP, Martin PM, Bertram T, Streit WJ. Differential activation of microglia and astrocytes following trimethyltin induced neurodegeneration. Neuroscience 1996;72(1):273-81. (Pubitemid 26092994)
51. Milligan ED, Twining C, Chacur M, Biedenkapp J, O'Connor K, Poole S, et al. Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats. J Neurosci 2003;23(3):1026-40. (Pubitemid 36206195)
52. Miyoshi K, Obata K, Kondo T, Okamura H, Noguchi K. Interleukin-18- mediated microglia/astrocyte interaction in the spinal cord enhances neuropathic pain processing after nerve injury. J Neurosci 2008;28(48):12775-87.
53. Mohri I, Taniike M, Taniguchi H, Kanekiyo T, Aritake K, Inui T, et al. Prostaglandin D2- mediated microglia/astrocyte interaction enhances astrogliosis and demyelination in twitcher. J Neurosci 2006;26(16):4383-93. (Pubitemid 44315397)
54. Nakagawa T, Wakamatsu K, Zhang N, Maeda S, Minami M, Satoh M, et al. Intrathecal administration of ATP produces long-lasting allodynia in rats: differential mechanisms in the phase of the induction and maintenance. Neuroscience 2007;147(2):445-55. (Pubitemid 46907446)
55. Naus CC, Bechberger JF, Zhang Y, Venance L, Yamasaki H, Juneja SC, et al. Altered gap junctional communication, intercellular signaling, and growth in cultured astrocytes deficient in connexin43. J Neurosci Res 1997;49:528-40. (Pubitemid 27381240)
56. Nedergaard M, Dirnagl U. Role of glial cells in cerebral ischemia. Glia 2005;50(4):281-6. (Pubitemid 40780834)
57. Nedergaard M, Ransom B, Goldman SA. New roles for astrocytes: redefining the functional architecture of the brain. Trends Neurosci 2003;26(10):523-30. (Pubitemid 37176906)
58. Nimmerjahn A, Kirchhoff F, Helmchen F. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 2005;308(5726):1314-8. (Pubitemid 40746128)
59. Norenberg W, Cordes A, Blohbaum G, Frohlich R, Illes P. Coexistence of purino- and pyrimidinoceptors on activated rat microglial cells. Br J Pharmacol 1997;121(6): 1087-98. (Pubitemid 27303576)
60. Ramírez G, Toro R, Döbeli H, von Bernhardi R. Protection of rat primary hippocampal cultures from A beta cytotoxicity by pro-inflammatory molecules is mediated by astrocytes. Neurobiol Dis 2005;19(1-2):243-54. (Pubitemid 40544742)
61. Reali C, Scintu F, Pillai R, Donato R, Michetti F, Sogos V. S100B counteracts effects of the neurotoxicant trimethyltin on astrocytes and microglia. J Neurosci Res 2005;81(5): 677-86. (Pubitemid 41532163)
62. Rouach N, Avignone E, Meme W, Koulakoff A, Venance L, Blomstrand F, et al. Gap junctions and connexin expression in the normal and pathological central nervous system. Biol Cell 2002a;94(7-8):457-75. (Pubitemid 36113697)
63. Rouach N, Calvo CF, Glowinski J, Giaume C. Brain macrophages inhibit gap junctional communication and downregulate connexin 43 expression in cultured astrocytes. Eur J Neurosci 2002b;15(2):403-7. (Pubitemid 35471963)
64. Sasaki Y, Hoshi M, Akazawa C, Nakamura Y, Tsuzuki H, Inoue K, et al. Selective expression of Gi/o-coupled ATP receptor P2Y12 in microglia in rat brain. Glia 2003;44(3):242-50. (Pubitemid 37484475)
65. Scemes E. Components of astrocytic intercellular calcium signaling. Mol Neurobiol 2000;22(1 -3):167-79.
66. Scemes E, Dermietzel R, Spray DC. Calcium waves between astrocytes from Cx43 knockout mice. Glia 1998;24:65-73. (Pubitemid 28370213)
67. 2+ waves trigger responses in microglial cells in brain slices. FASEB J 2002;16(2): 255-7.
68. Shaftel SS, Kyrkanides S, Olschowka JA, Miller JN, Johnson RE, O'Banion MK. Sustained hippocampal IL-1β overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology. J Clin Invest 2007;117(6):1595-604. (Pubitemid 46871344)
69. Shigemoto-Mogami Y, Koizumi S, Tsuda M, Ohsawa K, Kohsaka S, Inoue K. Mechanisms underlying extracellular ATP-evoked interleukin-6 release in mouse microglial cell line, MG-5. J Neurochem 2001;78(6):1339-49. (Pubitemid 32899765)
70. Smits HA, van Beelen AJ, de Vos NM, Rijsmus A, van der Bruggen T, Verhoef J, et al. Activation of human macrophages by amyloid-beta is attenuated by astrocytes. J Immunol 2001;166(11):6869-76. (Pubitemid 32467233)
71. Suzuki T, Hide I, Ido K, Kohsaka S, Inoue K, Nakata Y. Production and release of neuroprotective tumor necrosis factor by P2X7 receptor-activated microglia. J Neurosci 2004;24(1):1-7. (Pubitemid 38181664)
72. Thornton P, Pinteaux E, Gibson RM, Allan SM, Rothwell NJ. Interleukin-1-induced neurotoxicity is mediated by glia and requires caspase activation and free radical release. J Neurochem 2006;98(1):258-66. (Pubitemid 43882950)
73. Tichauer J, Saud K, von Bernhardi R. Modulation by astrocytes of microglial cell-mediated neuroinflammation: effect on the activation of microglial signaling pathways. Neuroimmunomodulation 2007;14(3-4):168-74. (Pubitemid 350249113)
74. Verderio C, Matteoli M. ATP mediates calcium signaling between astrocytes and microglial cells: modulation by IFN-gamma. J Immunol 2001;166(10):6383-91. (Pubitemid 32440772)
75. Verge GM, Milligan ED, Maier SF, Watkins LR, Naeve GS, Foster AC. Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions. Eur J Neurosci 2004;20(5): 1150-60. (Pubitemid 39233569)
76. Verkhratsky A, Steinhauser C. Ion channels in glial cells. Brain Res Brain Res Rev 2000;32(2-3):380-412. (Pubitemid 30171314)
77. von Bernhardi R, Eugenín J. Microglial reactivity to beta-amyloid is modulated by astrocytes and proinflammatory factors. Brain Res 2004;1025(1-2):186-93. (Pubitemid 39349537)
78. von Bernhardi R, Ramirez G. Microglia-astrocytes interaction in Alzheimer's disease: friends or foes for the nervous system? Biol Res 2001;34(2):123-8. (Pubitemid 32952126)
79. von Bernhardi R, Ramírez G, Toro R, Eugenín J. Pro-inflammatory conditions promote neuronal damage mediated by amyloid precursor protein and decrease its phagocytosis and degradation by microglial cells in culture. Neurobiol Dis 2007;26(1):153-64. (Pubitemid 46436495)
80. Wang J, Crawford K, Yuan M, Wang H, Gorry PR, Gabuzda D. Regulation of CC chemokine receptor 5 and CD4 expression and human immunodeficiency virus type 1 replication in human macrophages and microglia by T helper type 2 cytokines. J Infect Dis 2002;185(7):885-97. (Pubitemid 34274431)
81. Watkins LR, Maier SF. Glia: a novel drug discovery target for clinical pain. Nat Rev Drug Discov 2003;2(12):973-85. (Pubitemid 37540579)
82. Zanotti S, Charles A. Extracellular calcium sensing by glial cells: low extracellular calcium induces intracellular calcium release and intercellular signaling. J Neurochem 1997;69:594-602. (Pubitemid 27327959)