Pro-inflammatory conditions promote neuronal damage mediated by Amyloid Precursor Protein and decrease its phagocytosis and degradation by microglial cells in culture

Neurobiology of Disease

Volumn 26, Issue 1, 2007, Pages 153-164

  von Bernhardi, Rommy ^a   Ramírez, Gigliola ^a   Toro, Rodrigo ^a   Eugenín, Jaime ^b  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^b UNIVERSIDAD DE SANTIAGO DE CHILE   (Chile)

Author keywords

amyloid; Alzheimer's disease; APP processing; Astrocytes; Glia; Inflammation; Microglia; Neurotoxicity

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BIOTIN; LIPOPOLYSACCHARIDE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; EMBRYO; INFLAMMATION; MICROGLIA; NERVE CELL CULTURE; NERVE CELL LESION; NERVE DEGENERATION; NEUROPATHOLOGY; NEUROTOXICITY; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN TRANSPORT; RAT;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; BIOTIN; CELLS, CULTURED; HIPPOCAMPUS; HORSERADISH PEROXIDASE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MICROGLIA; NEURONS; PHAGOCYTOSIS; RATS; RATS, SPRAGUE-DAWLEY; SERUM ALBUMIN, BOVINE; STREPTAVIDIN; TETRAZOLIUM SALTS; THIAZOLES;

EID: 33947234997     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2006.12.006     Document Type: Article

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