TGF-β1 blockade of microglial chemotaxis toward Aβ aggregates involves SMAD signaling and down-regulation of CCL5

Journal of Neuroinflammation

Volumn 7, Issue , 2010, Pages

  Huang, Wei Chao ^a   Yen, Feng Chang ^b   Shie, Feng Shiun ^c   Pan, Chih Ming ^a   Shiao, Young Ji ^d   Yang, Cheng Ning ^a   Huang, Fong Lee ^a   Sung, Yen Jen ^a   Tsay, Huey Jen ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b CHENG HSIN REHABILITATION MEDICAL CENTER   (Taiwan)

^c NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^d NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; AMYLOID BETA PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA1; 1,3 DIOXOLANE DERIVATIVE; 4 (5 BENZO(1,3)DIOXOL 5 YL 4 PYRIDIN 2 YL 1H IMIDAZOL 2 YL)BENZAMIDE; 4-(5-BENZO(1,3)DIOXOL-5-YL-4-PYRIDIN-2-YL-1H-IMIDAZOL-2-YL)BENZAMIDE; BENZAMIDE DERIVATIVE; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; MICROGLIA; NERVOUS SYSTEM INFLAMMATION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PROTEIN AGGREGATION; PROTEIN PHOSPHORYLATION; RAT; SENILE PLAQUE; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; CELL MOTION; CHEMOTAXIS; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; IMMUNOLOGY; PHOSPHORYLATION; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

AMYLOID BETA-PROTEIN; ANIMALS; BENZAMIDES; BLOTTING, WESTERN; CELL LINE; CELL MOVEMENT; CHEMOKINE CCL5; CHEMOTAXIS; DIOXOLES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; MICROGLIA; PHOSPHORYLATION; RATS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 77951617994     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-7-28     Document Type: Article

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