Soluble factors from IL-1β-stimulated astrocytes activate NR1a/NR2B receptors: Implications for HIV-1-induced neurodegeneration

Biochemical and Biophysical Research Communications

Volumn 402, Issue 2, 2010, Pages 241-246

  Jing, Tao ^a   Wu, Li ^a   Borgmann, Kathleen ^b   Surendran, Sankar ^b   Ghorpade, Anuja ^b   Liu, Jianuo ^a   Xiong, Huangui ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

Author keywords

Astrocyte; HIV 1; IL 1 ; NMDA receptor; Voltage clamp; Xenopus oocyte

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; INTERLEUKIN 1BETA; INTERLEUKIN 8; INTERSTITIAL COLLAGENASE; MATRILYSIN; MONOCYTE CHEMOTACTIC PROTEIN 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL ACTIVATION; CONTROLLED STUDY; CULTURE MEDIUM; FEMALE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; NERVE DEGENERATION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; XENOPUS;

ANIMALS; ASTROCYTES; CELLS, CULTURED; CHEMOKINE CCL2; CULTURE MEDIA, CONDITIONED; HIV-1; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-8; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 7; NEURODEGENERATIVE DISEASES; OOCYTES; RECEPTORS, N-METHYL-D-ASPARTATE; XENOPUS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 78149465319     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.10.006     Document Type: Article

References (35)

1. Glass J.D., Fedor H., Wesselingh S.L., McArthur J.C. Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia. Ann. Neurol. 1995, 38:755-762.
2. Takahashi K., Wesselingh S.L., Griffin D.E., McArthur J.C., Johnson R.T., Glass J.D. Localization of HIV-1 in human brain using polymerase chain reaction/in situ hybridization and immunocytochemistry. Ann. Neurol. 1996, 39:705-711.
3. Erichsen D., Lopez A.L., Peng H., Niemann D., Williams C., Bauer M., Morgello S., Cotter R.L., Ryan L.A., Ghorpade A., Gendelman H.E., Zheng J. Neuronal injury regulates fractalkine: relevance for HIV-1 associated dementia. J. Neuroimmunol. 2003, 138:144-155.
4. Levine A.J., Singer E.J., Sinsheimer J.S., Hinkin C.H., Papp J., Dandekar S., Giovanelli A., Shapshak P. CCL3 genotype and current depression increase risk of HIV-associated dementia. Neurobehav. HIV Med. 2009, 1:1-7.
5. Gardner J., Borgmann K., Deshpande M.S., Dhar A., Wu L., Persidsky R., Ghorpade A. Potential mechanisms for astrocyte-TIMP-1 downregulation in chronic inflammatory diseases. J. Neurosci. Res. 2006, 83:1281-1292.
6. Suryadevara R., Holter S., Borgmann K., Persidsky R., Labenz-Zink C., Persidsky Y., Gendelman H.E., Wu L., Ghorpade A. Regulation of tissue inhibitor of metalloproteinase-1 by astrocytes: links to HIV-1 dementia. Glia 2003, 44:47-56.
7. Saito Y., Sharer L.R., Epstein L.G., Michaels J., Mintz M., Louder M., Golding K., Cvetkovich T.A., Blumberg B.M. Overexpression of nef as a marker for restricted HIV-1 infection of astrocytes in postmortem pediatric central nervous tissue. Neuorology 1994, 44f:474-481.
8. Brack-Werner R. Astrocytes: HIV cellular reservoirs and important participants in neuropathogenesis. Aids 1999, 13:1-22.
9. Kaul M., Garden G.A., Lipton S.A. Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature 2001, 410:988-994.
10. Kou W., Banerjee S., Eudy J., Smith L.M., Persidsky R., Borgmann K., Wu L., Sakhuja N., Deshpande M.S., Walseth T.F., Ghorpade A. CD38 regulation in activated astrocytes: implications for neuroinflammation and HIV-1 brain infection. J. Neurosci. Res. 2009, 87:2326-2339.
11. Boven L.A., Vergnolle N., Henry S.D., Silva C., Imai Y., Holden J., Warren K., Hollenberg M.D., Power C. Up-regulation of proteinase-activated receptor 1 expression in astrocytes during HIV encephalitis. J. Immunol. 2003, 170:2638-2646.
12. Dou H., Morehead J., Bradley J., Gorantla S., Ellison B., Kingsley J., Smith L.M., Chao W., Bentsman G., Volsky D.J., Gendelman H.E. Neuropathologic and neuroinflammatory activities of HIV-1-infected human astrocytes in murine brain. Glia 2006, 54:81-93.
13. Bliss T.V., Collingridge G.L. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 1993, 361:31-39.
14. Stys P.K., Lipton S.A. White matter NMDA receptors: an unexpected new therapeutic target?. Trends Pharmacol. Sci. 2007, 28:561-566.
15. Collins M.A., Neafsey E.J., Wang K., Achille N.J., Mitchell R.M., Sivaswamy S. Moderate ethanol preconditioning of rat brain cultures engenders neuroprotection against dementia-inducing neuroinflammatory proteins: possible signaling mechanisms. Mol. Neurobiol. 2010, 41:420-425.
16. Traynelis S.F., Wollmuth L.P., McBain C.J., Menniti F.S., Vance K.M., Ogden K.K., Hansen K.B., Yuan H., Myers S.J., Dingledine R., Sibley D. Glutamate receptor ion channels: structure, regulation, and function. Pharmacol. Rev. 2010, 62:405-496.
17. Lipton S.A. Ca2+, N-methyl-d-aspartate receptors, and AIDS-related neuronal injury. Int. Rev. Neurobiol. 1994, 36:1-27.
18. Lipton S.A. Similarity of neuronal cell injury and death in AIDS dementia and focal cerebral ischemia: potential treatment with NMDA open-channel blockers and nitric oxide-related species. Brain Pathol. 1996, 6:507-517.
19. Toggas S.M., Masliah E., Mucke L. Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine. Brain Res. 1996, 706:303-307.
20. Ushijima H., Nishio O., Klocking R., Perovic S., Muller W.E. Exposure to gp120 of HIV-1 induces an increased release of arachidonic acid in rat primary neuronal cell culture followed by NMDA receptor-mediated neurotoxicity. Eur. J. Neurosci. 1995, 7:1353-1359.
21. Sas A.R., Bimonte-Nelson H.A., Tyor W.R. Cognitive dysfunction in HIV encephalitic SCID mice correlates with levels of Interferon-alpha in the brain. Aids 2007, 21:2151-2159.
22. Muller W.E., Pergande G., Ushijima H., Schleger C., Kelve M., Perovic S. Neurotoxicity in rat cortical cells caused by N-methyl-d-aspartate (NMDA) and gp120 of HIV-1: induction and pharmacological intervention. Prog. Mol. Subcell. Biol. 1996, 16:44-57.
23. Janabi N., Di Stefano M., Wallon C., Hery C., Chiodi F., Tardieu M. Induction of human immunodeficiency virus type 1 replication in human glial cells after proinflammatory cytokines stimulation: effect of IFNgamma, IL1beta, and TNFalpha on differentiation and chemokine production in glial cells. Glia 1998, 23:304-315.
24. Peng H., Erdmann N., Whitney N., Dou H., Gorantla S., Gendelman H.E., Ghorpade A., Zheng J. HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta. Glia 2006, 54:619-629.
25. Canki M., Thai J.N., Chao W., Ghorpade A., Potash M.J., Volsky D.J. Highly productive infection with pseudotyped human immunodeficiency virus type 1 (HIV-1) indicates no intracellular restrictions to HIV-1 replication in primary human astrocytes. J. Virol. 2001, 75:7925-7933.
26. Ghorpade A., Holter S., Borgmann K., Persidsky R., Wu L. HIV-1 and IL-1 beta regulate Fas ligand expression in human astrocytes through the NF-kappa B pathway. J. Neuroimmunol. 2003, 141:141-149.
27. Bear C.E., Duguay F., Naismith A.L., Kartner N., Hanrahan J.W., Riordan J.R. Cl-channel activity in Xenopus oocytes expressing the cystic fibrosis gene. J. Biol. Chem. 1991, 266:19142-19145.
28. Xiong H., McCabe L., Skifter D., Monaghan D.T., Gendelman H.E. Activation of NR1a/NR2B receptors by monocyte-derived macrophage secretory products: implications for human immunodeficiency virus type one-associated dementia. Neurosci. Lett. 2003, 341:246-250.
29. Keblesh J.P., Reiner B.C., Liu J., Xiong H. Pathogenesis of human immunodeficiency virus type-1 (HIV-1)-associated dementia: role of voltage-gated potassium channels. Retrovirology 2008, 2:1-10.
30. Reiner B.C., Keblesh J.P., Xiong H. Methamphetamine abuse, HIV infection, and neurotoxicity. Int. J. Physiol. Pathophysiol. Pharmacol. 2009, 1:162-179.
31. Minagar A., Shapshak P., Fujimura R., Ownby R., Heyes M., Eisdorfer C. The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis. J. Neurol. Sci. 2002, 202:13-23.
32. Lipton S.A. AIDS-related dementia and calcium homeostasis. Ann. NY Acad. Sci. 1994, 747:205-224.
33. Ahlemeyer B., Kolker S., Zhu Y., Hoffmann G.F., Krieglstein J. Increase in glutamate-induced neurotoxicity by activated astrocytes involves stimulation of protein kinase C. J. Neurochem. 2002, 82:504-515.
34. Choi D.W., Koh J.Y., Peters S. Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists. J. Neurosci. 1988, 8:185-196.
35. Deshpande M., Zheng J., Borgmann K., Persidsky R., Wu L., Schellpeper C., Ghorpade A. Role of activated astrocytes in neuronal damage: potential links to HIV-1-associated dementia. Neurotox. Res. 2005, 7:183-192.