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Volumn 14, Issue 3, 2010, Pages 185-189

Activation of PPARα attenuates IFNγ and IL-1β-induced cell proliferation in astrocytes: Involvement of IL-6 independent pathway

Author keywords

Astrocytes; Bezafibrate; Fenofibrate; IL 6; Proliferation

Indexed keywords

BEZAFIBRATE; FENOFIBRATE; FIBRIC ACID DERIVATIVE; GAMMA INTERFERON; INTERLEUKIN 1BETA; INTERLEUKIN 6; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA;

EID: 77954889420     PISSN: 12264512     EISSN: None     Source Type: Journal    
DOI: 10.4196/kjpp.2010.14.3.185     Document Type: Article
Times cited : (3)

References (20)
  • 3
    • 0033305213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Nuclear control of metabolism
    • Desvergne B, Wahli W. Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr Rev. 1999;20: 649-688.
    • (1999) Endocr Rev , vol.20 , pp. 649-688
    • Desvergne, B.1    Wahli, W.2
  • 4
    • 0347753697 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptors and cancers: Complex stories
    • Michalik L, Desvergne B, Wahli W. Peroxisome-proliferator-activated receptors and cancers: complex stories. Nat Rev Cancer. 2004;4:61-70.
    • (2004) Nat Rev Cancer , vol.4 , pp. 61-70
    • Michalik, L.1    Desvergne, B.2    Wahli, W.3
  • 5
    • 77951457202 scopus 로고    scopus 로고
    • Fibrates, glitazones, and peroxisome proliferator-activated receptors
    • Lalloyer F, Staels B. Fibrates, glitazones, and peroxisome proliferator-activated receptors. Arterioscler Thromb Vasc Biol. 2010;30:894-899.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 894-899
    • Lalloyer, F.1    Staels, B.2
  • 7
    • 17144371459 scopus 로고    scopus 로고
    • A novel role of lactosylceramide in the regulation of tumor necrosis factor alpha-mediated proliferation of rat primary astrocytes. Implications for astrogliosis following neurotrauma
    • Pannu R, Singh AK, Singh I. A novel role of lactosylceramide in the regulation of tumor necrosis factor alpha-mediated proliferation of rat primary astrocytes. Implications for astrogliosis following neurotrauma. J Biol Chem. 2005;280:13742-13751.
    • (2005) J Biol Chem , vol.280 , pp. 13742-13751
    • Pannu, R.1    Singh, A.K.2    Singh, I.3
  • 8
    • 41049102868 scopus 로고    scopus 로고
    • Bone marrow stromal cells reduce ischemia-induced astrocytic activation in vitro
    • Gao Q, Li Y, Shen L, Zhang J, Zheng X, Qu R, Liu Z, Chopp M. Bone marrow stromal cells reduce ischemia-induced astrocytic activation in vitro. Neuroscience. 2008;152:646-655.
    • (2008) Neuroscience , vol.152 , pp. 646-655
    • Gao, Q.1    Li, Y.2    Shen, L.3    Zhang, J.4    Zheng, X.5    Qu, R.6    Liu, Z.7    Chopp, M.8
  • 9
    • 0025092159 scopus 로고
    • Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor
    • Selmaj KW, Farooq M, Norton WT, Raine CS, Brosnan CF. Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor. J Immunol. 1990;144: 129-135.
    • (1990) J Immunol , vol.144 , pp. 129-135
    • Selmaj, K.W.1    Farooq, M.2    Norton, W.T.3    Raine, C.S.4    Brosnan, C.F.5
  • 10
    • 0030952937 scopus 로고    scopus 로고
    • Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta
    • Forman BM, Chen J, Evans RM. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc Natl Acad Sci USA. 1997;94:4312-4317.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4312-4317
    • Forman, B.M.1    Chen, J.2    Evans, R.M.3
  • 11
    • 33846468972 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma agonists suppress the production of IL-12 family cytokines by activated glia
    • Xu J, Drew PD. Peroxisome proliferator-activated receptor-gamma agonists suppress the production of IL-12 family cytokines by activated glia. J Immunol. 2007;178:1904-1913.
    • (2007) J Immunol , vol.178 , pp. 1904-1913
    • Xu, J.1    Drew, P.D.2
  • 12
    • 33745894996 scopus 로고    scopus 로고
    • Effects of fenofibrate on the proliferation and apoptosis and nitric oxide synthase expression of cultured human umbilical vein endothelial cells induced by lysophosphatidylcholine
    • Sun GJ, Xie XM, Xing Y, Yan WH, Yang TL, Yu GL. Effects of fenofibrate on the proliferation and apoptosis and nitric oxide synthase expression of cultured human umbilical vein endothelial cells induced by lysophosphatidylcholine. Zhong Nan Da Xue Xue Boo Yi Xue Ban. 2006;31:373-378.
    • (2006) Zhong Nan Da Xue Xue Boo Yi Xue Ban , vol.31 , pp. 373-378
    • Sun, G.J.1    Xie, X.M.2    Xing, Y.3    Yan, W.H.4    Yang, T.L.5    Yu, G.L.6
  • 14
    • 1542305504 scopus 로고    scopus 로고
    • Glitazones differentially regulate primary astrocyte and glioma cell survival. Involvement of reactive oxygen species and peroxisome proliferator-activated receptor-gamma
    • Perez-Ortiz JM, Tranque P, Vaquera CF, Domingo B, Molina F, Calvo S, Jordan J, Cena V, Llopis J. Glitazones differentially regulate primary astrocyte and glioma cell survival. Involvement of reactive oxygen species and peroxisome proliferator-activated receptor-gamma. J Biol Chem. 2004;279:8976-8985.
    • (2004) J Biol Chem , vol.279 , pp. 8976-8985
    • Perez-Ortiz, J.M.1    Tranque, P.2    Vaquera, C.F.3    Domingo, B.4    Molina, F.5    Calvo, S.6    Jordan, J.7    Cena, V.8    Llopis, J.9
  • 15
    • 11144333682 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor alpha activator fenofibrate inhibits endothelin-1-induced cardiac fibroblast proliferation
    • Ogata T, Miyauchi T, Irukayama-Tomobe Y, Takanashi M, Goto K, Yamaguchi I. The peroxisome proliferator-activated receptor alpha activator fenofibrate inhibits endothelin-1-induced cardiac fibroblast proliferation. J Cardiovasc Pharmacol. 2004;44 Suppl 1:S279-282.
    • (2004) J Cardiovasc Pharmacol , vol.44 , Issue.SUPPL. 1
    • Ogata, T.1    Miyauchi, T.2    Irukayama-Tomobe, Y.3    Takanashi, M.4    Goto, K.5    Yamaguchi, I.6
  • 16
    • 77952745811 scopus 로고    scopus 로고
    • Micro RNA-125b (miRNA-125b) function in astrogliosis and glial cell proliferation
    • Pogue AI, Cui JG, Li YY, Zhao Y, Culicchia F, Lukiw WJ. Micro RNA-125b (miRNA-125b) function in astrogliosis and glial cell proliferation. Neurosci Lett. 2010;476:18-22.
    • (2010) Neurosci Lett , vol.476 , pp. 18-22
    • Pogue, A.I.1    Cui, J.G.2    Li, Y.Y.3    Zhao, Y.4    Culicchia, F.5    Lukiw, W.J.6
  • 17
    • 38849137193 scopus 로고    scopus 로고
    • Effect of astrocyte-targeted production of IL-6 on traumatic brain injury and its impact on the cortical transcriptome
    • Quintana A, Molinero A, Borup R, Nielsen FC, Campbell IL, Penkowa M, Hidalgo J. Effect of astrocyte-targeted production of IL-6 on traumatic brain injury and its impact on the cortical transcriptome. Dev Neurobiol. 2008;68:195-208.
    • (2008) Dev Neurobiol , vol.68 , pp. 195-208
    • Quintana, A.1    Molinero, A.2    Borup, R.3    Nielsen, F.C.4    Campbell, I.L.5    Penkowa, M.6    Hidalgo, J.7
  • 18
    • 0142090539 scopus 로고    scopus 로고
    • Compromised reactive microgliosis in MPTP-lesioned IL-6 KO mice
    • Cardenas H, Bolin LM. Compromised reactive microgliosis in MPTP-lesioned IL-6 KO mice. Brain Res. 2003;985:89-97.
    • (2003) Brain Res , vol.985 , pp. 89-97
    • Cardenas, H.1    Bolin, L.M.2
  • 19
    • 0033667998 scopus 로고    scopus 로고
    • Impaired inflammatory response and increased oxidative stress and neurodegeneration after brain injury in interleukin-6-deficient mice
    • Penkowa M, Giralt M, Carrasco J, Hadberg H, Hidalgo J. Impaired inflammatory response and increased oxidative stress and neurodegeneration after brain injury in interleukin-6-deficient mice. Glia. 2000;32:271-285.
    • (2000) Glia , vol.32 , pp. 271-285
    • Penkowa, M.1    Giralt, M.2    Carrasco, J.3    Hadberg, H.4    Hidalgo, J.5
  • 20
    • 33746079214 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-alpha and retinoid X receptor agonists inhibit inflammatory responses of astrocytes
    • Xu J, Chavis JA, Racke MK, Drew PD. Peroxisome proliferator-activated receptor-alpha and retinoid X receptor agonists inhibit inflammatory responses of astrocytes. J Neuroimmunol. 2006;176:95-105.
    • (2006) J Neuroimmunol , vol.176 , pp. 95-105
    • Xu, J.1    Chavis, J.A.2    Racke, M.K.3    Drew, P.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.