Is damage in central nervous system due to inflammation?

Autoimmunity Reviews

Volumn 3, Issue 4, 2004, Pages 251-260

  Chavarria, A ^a   Alcocer Varela, J ^b  

^a INSTITUTO DE INVESTIGACIONES BIOMÉDICAS   (Mexico)

^b INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

Author keywords

Damage; Multiple sclerosis; Neuroinflammation

Indexed keywords

CELL ADHESION MOLECULE; CHEMOKINE; CHEMOKINE RECEPTOR; CYTOKINE;

ALLERGIC ENCEPHALOMYELITIS; ASTROCYTE; B LYMPHOCYTE; BLOOD BRAIN BARRIER; BRAIN FUNCTION; BRAIN INJURY; BRAIN NERVE CELL; CELL TYPE; CENTRAL NERVOUS SYSTEM; CHEMOTAXIS; ENCEPHALITIS; ENDOTHELIUM; HUMAN; IMMUNE SYSTEM; INFLAMMATION; MACROPHAGE; MAST CELL; MICROGLIA; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; REVIEW; T LYMPHOCYTE;

ANIMALS; ANTIGEN-PRESENTING CELLS; CD4-POSITIVE T-LYMPHOCYTES; CENTRAL NERVOUS SYSTEM; CHEMOKINES; CHEMOTAXIS; CYTOKINES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; HUMANS; INFLAMMATION; INTERFERON TYPE II; MODELS, BIOLOGICAL; MULTIPLE SCLEROSIS; T-LYMPHOCYTES; TH1 CELLS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 3042731246     PISSN: 15689972     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autrev.2003.09.006     Document Type: Review

References (40)

1. Nathan C. Points of control in inflammation. Nature. 420:2002;846-852
2. McGeer P.L., McGeer E.G. Inflammation, autotoxicity and Alzheimer disease. Neurobiol Aging. 22:2001;799-809
3. Paterson P.Y. Transfer of allergic encephalomyelitis in rats by means of lymph node cells. J Exp Med. 111:1960;119-135
4. Hickey W. Leucocyte traffic in the central nervous system: the participants and their roles. Semin Immunol. 11:1999;125-137
5. Knopf P., Harling-Berg C., Cserr H., et al. Antigen-dependent intrathecal antibody synthesis in the normal rat brain: tissue entry and local retention of antigen-specific B cells. J Immunol. 161:1998;692-701
6. Krakowski M.L., Owens T. The central nervous system environment controls effector CD4+ T cell cytokine profile in experimental allergic encephalomyelitis. Eur J Immunol. 27:1997;2840-2847
7. Karpus W.J., Ransohoff R.M. Chemokine regulation of experimental autoimmune encephalomyelitis: temporal and spatial expression patterns govern disease pathogenesis. J Immunol. 161:1998;2667-2671
8. Seabrook T.J., Hay J.B. Intracerebroventricular infusions of TNF-alpha preferentially recruit blood lymphocytes and induce a perivascular leukocyte infiltrate. J Neuroimmunol. 113:2001;81-88
9. Yamaoka J., Kabashima K., Kawanishi M., Toda K.I., Miyachi Y. Cytotoxicity of IFN-gamma and TNF-alpha for vascular endothelial cell is mediated by nitric oxide. Biochem Biophys Res. 291:2002;780-790
10. Orlikowski D., Chazaud B., Plonquet A., et al. Monocyte chemoattractant protein 1 and chemokine receptor CCR2 productions in Guillain-Barré syndrome and experimental autoimmune neuritis. J Neuroimmunol. 134:2003;118-127
11. Cross A.K., Woodroofe M.N. Chemokine modulation of matrix metalloproteinase and TIMP production in adult rat brain microglia and a human microglial cell line in vitro. Glia. 28:1999;183-189
12. Cross A.H., Trotter J.L., Lyons J. B cells and antibodies in CNS demyelinating disease. J Neuroimmunol. 112:2001;1-14
13. Williamson R.A., Burgoon M.P., Owens G.P., et al. Anti-DNA antibodies are a major component of the intrathecal B cell response in multiple sclerosis. Proc Natl Acad Sci. 98:2001;1793-1798
14. Genain C.P., Cannella B., Hauser S.L., Raine C.S. Identification of autoantibodies associated with myelin damage in multiple sclerosis. Nat Med. 5:1999;170-175
15. Columba-Cabezas S., Serafini B., Ambrosini E., Aloisi F. Lymphoid chemokines CCL19 and CCL21 are expressed in the central nervous system during experimental autoimmune encephalomyelitis: implications for the maintenance of chronic neuroinflammation. Brain Pathol. 13:2003;38-51
16. Benoist C., Mathis D. Mast cells in autoimmune disease. Nature. 420:2002;875-878
17. Shi F.D., Takeda K., Akira S., Sarvetnick N., Ljunggren H.G. IL-18 directs autoreactive T cells and promotes autodestruction in the central nervous system via induction of IFN-gamma by NK cells. J Immunol. 165:2000;3099-3104
18. Pagenstecher A., Lassmann S., Carson M.J., Kincaid C.L., Stalder A.K., Campbell I.L. Astrocyte-targeted expression of IL-12 induces active cellular immune responses in the central nervous system and modulates experimental allergic encephalomyelitis. J Immunol. 164:2000;4481-4492
19. Smeltz R.B., Wolf N.A., Swanborg R.H. Inhibition of autoimmune T cell responses in the DA rat by bone marrow-derived NK cells in vitro: implications for autoimmunity. J Immunol. 163:1999;1390-1397
20. Serafini B., Columba-Cabezas S., Di Rosa F., Aloisi F. Intracerebral recruitment and maturation of dendritic cells in the onset and progression of experimental autoimmune encephalomyelitis. Am J Pathol. 157:2000;1991-2002
21. Matyszak M.K., Perry H. The potential role of dendritic cells in immune-mediated inflammatory diseases in the central nervous system. Neuroscience. 74:1996;599-608
22. Ambrosini E., Columba-Cabezas S., Serafini B., Muscella A., Aloisi F. Astrocytes are the major intracerebral source of macrophage inflammatory protein-3alpha/CCL20 in relapsing experimental autoimmune encephalomyelitis and in vitro. Glia. 41:2003;290-300
23. Fischer H.G., Reichmann G. Brain dendritic cells and macrophages/ microglia in central nervous system inflammation. J Immunol. 166:2001;2717-2726
24. Piehl F., Lidman O. Neuroinflammation in the rat - CNS cells and their role in the regulation of immune reactions. Immunol Rev. 184:2001;212-225
25. Cua D.J., Sherlock J., Chen Y., et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature. 421:2003;744-748
26. Polfliet M.M., van de Veerdonk F., Dopp E.A., et al. The role of perivascular and meningeal macrophages in experimental allergic encephalomyelitis. J Neuroimmunol. 122:2002;1-8
27. Olsson T. Neuronal interferon-γ immunoreactive molecule: bioactivities and purification. Eur J Immunol. 24:1994;308-314
28. Flugel A. Neuronal Fas-L induces cell death of encephalitogenic T lymphocytes. Brain Pathol. 10:2000;353-364
29. Wong D., Prameya R., Dorovini-Zis K. In vitro adhesion and migration of T lymphocytes across monolayers of human brain microvessel endothelial cells: regulation by ICAM-1, VCAM-1, E-selectin and PECAM-1. J Neuropathol Exp Neurol. 58:1999;138-152
30. Omari K.M., Dorovini-Zis K. CD40 expressed by human brain endothelial cells regulates CD4+ T cell adhesion to endothelium. J Neuroimmunol. 134:2003;166-178
31. Gerritse K., Laman J.D., Noelle R.J., et al. CD40-CD40 ligand interactions in experimental allergic encephalomyelitis and multiple sclerosis. Proc Natl Acad Sci. 93:1996;2499-2504
32. Nicoletti F., Di Marco R., Mangano K., et al. Increased serum levels of interleukin-18 in patients with multiple sclerosis. Neurology. 57:2001;342-344
33. Misko T.P., Trotter J.L., Cross A.H. Mediation of inflammation by encephalitogenic cells: interferon gamma induction of nitric oxide synthase and cyclooxygenase 2. J Neuroimmunol. 61:1995;195-204
34. Benveniste E.N. Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis. J Mol Med. 75:1997;165-173
35. Pitt D., Werner P., Raine C.S. Glutamate excitotoxicity in a model of multiple sclerosis. Nat Med. 6:2000;67-70
36. Sharief M.K., Matthews H., Noori M.A. Expression ratios of the Bcl-2 family proteins and disease activity in multiple sclerosis. J Neuroimmunol. 134:2003;158-165
37. Torben S., Tani M., Jensen J., et al. Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients. J Clin Invest. 103:1999;807-815
38. Franciotta D., Martino G., Zardini E., et al. Serum and CSF levels of MCP-1 and IP-10 in multiple sclerosis patients with acute and stable disease and undergoing immunomodulatory therapies. J Neuroimmunol. 115:2001;192-198
39. Miyamoto K., Miyake S., Yamamura T. A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells. Nature. 413:2001;531-534
40. Chabot S., Williams G., Hamilton M., Sutherland G., Yong W. Mechanisms of IL-10 production in human microglia-T cell interaction. J Immunol. 162:1999;6819-6828