NAD+ depletion or PAR polymer formation: Which plays the role of executioner in ischaemic cell death?

Acta Physiologica

Volumn 203, Issue 1, 2011, Pages 225-234

  Siegel, C ^a   Mccullough, L D ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Caspase independent cell death; Energy metabolism; Nicotinamide adenine dinucleotide; Poly ADP ribose polymerase 1; Poly ADP ribose polymers

Indexed keywords

APOPTOSIS INDUCING FACTOR; CALCIUM ION; CASPASE; CASPASE 9; CYTOCHROME C; DOUBLE STRANDED DNA; METHYLNITRONITROSOGUANIDINE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NITRIC OXIDE; PEROXYNITRITE; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SIRTUIN;

ACETYLATION; ADENOSINE DIPHOSPHATE RIBOSYLATION; AMINO TERMINAL SEQUENCE; APOPTOSIS; BRAIN CELL; BRAIN MITOCHONDRION; CALCIUM TRANSPORT; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS; CHROMATIN CONDENSATION; DEPLETION; DNA BINDING; DNA DAMAGE; DNA STRAND BREAKAGE; ENERGY METABOLISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GLYCOLYSIS; METHYLATION; NERVE CELL CULTURE; NONHUMAN; OXIDATION; PHOSPHORYLATION; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN TRANSPORT; REVIEW; SEX DIFFERENCE; STROKE;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; FEMALE; HUMANS; MALE; NAD; POLY ADENOSINE DIPHOSPHATE RIBOSE; PROTEINS; SEX CHARACTERISTICS;

EID: 80051670852     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2010.02229.x     Document Type: Review

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