Mechanisms of reduced striatal NMDA excitotoxicity in type I nitric oxide synthase knock-out mice

Journal of Neuroscience

Volumn 17, Issue 18, 1997, Pages 6908-6917

  Ayata, Cenk ^a   Ayata, Gamze ^a   Hara, Hideaki ^a   Matthews, Russel T ^a   Beal, M Flint ^a   Ferrante, Robert J ^b,c   Endres, Matthias ^a   Kim, Albert ^a   Christie, Richard H ^a   Waeber, Christian ^a   Huang, Paul L ^a   Hyman, Bradley T ^a   Moskowitz, Michael A ^a,d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Stroke and Neurovascular Regulation Laboratory   (United States)

Author keywords

Apoptosis; DNA laddering; Excitotoxicity; Hydroxyl radical; Knock out mice; Neuronal nitric oxide synthase; Nitrotyrosine; NMDA; Striatum; TUNEL staining

Indexed keywords

7 NITROINDAZOLE; DIZOCILPINE; HYDROXYL RADICAL; N METHYL DEXTRO ASPARTIC ACID; NITRIC OXIDE SYNTHASE; TYROSINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; CORPUS STRIATUM; DNA STRAND BREAKAGE; DRUG MECHANISM; ENZYME MECHANISM; IMMUNOHISTOCHEMISTRY; MOUSE; NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL;

EID: 16944366580     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-18-06908.1997     Document Type: Article

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