Post-treatment with an inhibitor of poly(ADP-ribose) polymerase attenuates cerebral damage in focal ischemia

Brain Research

Volumn 829, Issue 1-2, 1999, Pages 46-54

  Takahashi, Kazushi ^a   Pieper, Andrew A ^b   Croul, Sidney E ^c   Zhang, Jie ^d   Snyder, Solomon H ^b   Greenberg, Joel H ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^d GUILFORD PHARMACEUTICALS INC   (United States)

Author keywords

Focal cerebral ischemia; Immunohistochemistry; Laser Doppler flowmetry; Middle cerebral artery occlusion; Neuroprotection; Poly(ADP ribose) polymerase; Rat

Indexed keywords

3,4 DIHYDRO 5 [4 (1 PIPERIDINYL)BUTOXY] 1(2H) ISOQUINOLINONE; ADENOSINE DIPHOSPHATE RIBOSE; DNA DIRECTED DNA POLYMERASE ALPHA; ISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN PROTECTION; DNA STRAND BREAKAGE; LASER DOPPLER FLOWMETRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

ANIMALS; ARTERIAL OCCLUSIVE DISEASES; CEREBRAL INFARCTION; CEREBROVASCULAR CIRCULATION; ENZYME INHIBITORS; IMMUNOHISTOCHEMISTRY; ISCHEMIC ATTACK, TRANSIENT; ISOQUINOLINES; MALE; PIPERIDINES; POLY(ADP-RIBOSE) POLYMERASES; RATS; RATS, LONG-EVANS;

EID: 0033594743     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)01335-9     Document Type: Article

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