메뉴 건너뛰기




Volumn 88, Issue 13, 2010, Pages 2765-2774

Sex differences in cerebral ischemia: Possible molecular mechanisms

Author keywords

Cell death; Epigenetics; Hormones; Organizational activational effects; Steroids; Stroke

Indexed keywords

CASPASE; POLY(ADENOSINE DIPHOSPHATE RIBOSE); SEX HORMONE;

EID: 77957241002     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22406     Document Type: Review
Times cited : (63)

References (95)
  • 2
    • 0033976986 scopus 로고    scopus 로고
    • Neuroprotective effects of female gonadal steroids in reproductively senescent female rats
    • Alkayed NJ, Murphy SJ, Traystman RJ, Hurn PD, Miller VM. 2000. Neuroprotective effects of female gonadal steroids in reproductively senescent female rats. Stroke 31:161-168.
    • (2000) Stroke , vol.31 , pp. 161-168
    • Alkayed, N.J.1    Murphy, S.J.2    Traystman, R.J.3    Hurn, P.D.4    Miller, V.M.5
  • 3
    • 1842867053 scopus 로고    scopus 로고
    • Effects of Conjugated Equine Estrogen in Postmenopausal Women with Hysterectomy: The Women's Health Initiative Randomized Controlled Trial
    • DOI 10.1001/jama.291.14.1701
    • Anderson GL, Limacher M, Assaf AR, Bassford T, Beresford SA, Black H, Bonds D, Brunner R, Brzyski R, Caan B, Chlebowski R, Curb D, Gass M, Hays J, Heiss G, Hendrix S, Howard BV, Hsia J, Hubbell A, Jackson R, Johnson KC, Judd H, Kotchen JM, Kuller L, LaCroix AZ, Lane D, Langer RD, Lasser N, Lewis CE, Manson J, Margolis K, Ockene J, O'Sullivan MJ, Phillips L, Prentice RL, Ritenbaugh C, Robbins J, Rossouw JE, Sarto G, Stefanick ML, Van Horn L, Wactawski-Wende J, Wallace R, Wassertheil-Smoller S. 2004. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA 291:1701-1712. (Pubitemid 38489892)
    • (2004) Journal of the American Medical Association , vol.291 , Issue.14 , pp. 1701-1712
    • Anderson, G.L.1    Limacher, M.2
  • 4
    • 65549139630 scopus 로고    scopus 로고
    • The organizational-activational hypothesis as the foundation for a unified theory of sexual differentiation of all mammalian tissues
    • Arnold AP. 2009. The organizational-activational hypothesis as the foundation for a unified theory of sexual differentiation of all mammalian tissues. Horm Behav 55:570-578.
    • (2009) Horm Behav , vol.55 , pp. 570-578
    • Arnold, A.P.1
  • 5
    • 65849420207 scopus 로고    scopus 로고
    • Brain sex differences and the organisation of juvenile social play behaviour
    • Auger AP, Olesen KM. 2009. Brain sex differences and the organisation of juvenile social play behaviour. J Neuroendocrinol 21:519-525.
    • (2009) J Neuroendocrinol , vol.21 , pp. 519-525
    • Auger, A.P.1    Olesen, K.M.2
  • 6
    • 0034649437 scopus 로고    scopus 로고
    • Parkinson's disease and parkinsonism in a longitudinal study: Two-fold higher incidence in men
    • ILSA Working Group. Italian Longitudinal Study on Aging
    • Baldereschi M, Di Carlo A, Rocca WA, Vanni P, Maggi S, Perissinotto E, Grigoletto F, Amaducci L, Inzitari D. 2000. Parkinson's disease and parkinsonism in a longitudinal study: two-fold higher incidence in men. ILSA Working Group. Italian Longitudinal Study on Aging. Neurology 55:1358-1363.
    • (2000) Neurology , vol.55 , pp. 1358-1363
    • Baldereschi, M.1    Di Carlo, A.2    Rocca, W.A.3    Vanni, P.4    Maggi, S.5    Perissinotto, E.6    Grigoletto, F.7    Amaducci, L.8    Inzitari, D.9
  • 8
    • 15244353967 scopus 로고    scopus 로고
    • X-inactivation profile reveals extensive variability in X-linked gene expression in females
    • DOI 10.1038/nature03479
    • Carrel L, Willard HF. 2005. X-inactivation profile reveals extensive variability in X-linked gene expression in females. Nature 434:400-404. (Pubitemid 40469185)
    • (2005) Nature , vol.434 , Issue.7031 , pp. 400-404
    • Carrel, L.1    Willard, H.F.2
  • 9
    • 0036785889 scopus 로고    scopus 로고
    • Sex chromosome genes directly affect brain sexual differentiation
    • Carruth LL, Reisert I, Arnold AP. 2002. Sex chromosome genes directly affect brain sexual differentiation. Nat Neurosci 5:933-934.
    • (2002) Nat Neurosci , vol.5 , pp. 933-934
    • Carruth, L.L.1    Reisert, I.2    Arnold, A.P.3
  • 11
    • 38449111023 scopus 로고    scopus 로고
    • Osteogenic potential of postnatal skeletal muscle-derived stem cells is influenced by donor sex
    • DOI 10.1359/jbmr.070702
    • Corsi KA, Pollett JB, Phillippi JA, Usas A, Li G, Huard J. 2007. Osteogenic potential of postnatal skeletal muscle-derived stem cells is influenced by donor sex. J Bone Miner Res 22:1592-1602. (Pubitemid 351229329)
    • (2007) Journal of Bone and Mineral Research , vol.22 , Issue.10 , pp. 1592-1602
    • Corsi, K.A.1    Pollett, J.B.2    Phillippi, J.A.3    Usas, A.4    Li, G.5    Huard, J.6
  • 12
    • 0037307565 scopus 로고    scopus 로고
    • Ablation of PLB exacerbates ischemic injury to a lesser extent in female than male mice: Protective role of NO
    • Cross HR, Kranias EG, Murphy E, Steenbergen C. 2003. Ablation of PLB exacerbates ischemic injury to a lesser extent in female than male mice: protective role of NO. Am J Physiol Heart Circ Physiol 284:H683-690.
    • (2003) Am J Physiol Heart Circ Physiol , vol.284
    • Cross, H.R.1    Kranias, E.G.2    Murphy, E.3    Steenbergen, C.4
  • 20
    • 0343517092 scopus 로고    scopus 로고
    • Biochemical markers of bone turnover, endogenous hormones and the risk of fractures in postmenopausal women: The OFELY study
    • Garnero P, Sornay-Rendu E, Claustrat B, Delmas PD. 2000. Biochemical markers of bone turnover, endogenous hormones and the risk of fractures in postmenopausal women: the OFELY study. J Bone Miner Res 15:1526-1536. (Pubitemid 30484522)
    • (2000) Journal of Bone and Mineral Research , vol.15 , Issue.8 , pp. 1526-1536
    • Patrick, G.1    Sornay-Rendu, E.2    Claustrat, B.3    Delmas, P.D.4
  • 21
    • 54349128377 scopus 로고    scopus 로고
    • Sex dimorphism in wound healing: The roles of sex steroids and macrophage migration inhibitory factor
    • Gilliver SC, Ruckshanthi JP, Hardman MJ, Nakayama T, Ashcroft GS. 2008. Sex dimorphism in wound healing: the roles of sex steroids and macrophage migration inhibitory factor. Endocrinology 149:5747-5757.
    • (2008) Endocrinology , vol.149 , pp. 5747-5757
    • Gilliver, S.C.1    Ruckshanthi, J.P.2    Hardman, M.J.3    Nakayama, T.4    Ashcroft, G.S.5
  • 22
    • 37349001257 scopus 로고    scopus 로고
    • Sex chromosome complement affects nociception in tests of acute and chronic exposure to morphine in mice
    • DOI 10.1016/j.yhbeh.2007.09.003, PII S0018506X07002127
    • Gioiosa L, Chen X, Watkins R, Klanfer N, Bryant CD, Evans CJ, Arnold AP. 2008a. Sex chromosome complement affects nociception in tests of acute and chronic exposure to morphine in mice. Horm Behav 53:124-130. (Pubitemid 350309370)
    • (2008) Hormones and Behavior , vol.53 , Issue.1 , pp. 124-130
    • Gioiosa, L.1    Chen, X.2    Watkins, R.3    Klanfer, N.4    Bryant, C.D.5    Evans, C.J.6    Arnold, A.P.7
  • 23
    • 52149102961 scopus 로고    scopus 로고
    • Sex chromosome complement affects nociception and analgesia in newborn mice
    • Gioiosa L, Chen X, Watkins R, Umeda EA, Arnold AP. 2008b. Sex chromosome complement affects nociception and analgesia in newborn mice. J Pain 9:962-969.
    • (2008) J Pain , vol.9 , pp. 962-969
    • Gioiosa, L.1    Chen, X.2    Watkins, R.3    Umeda, E.A.4    Arnold, A.P.5
  • 24
    • 0035682104 scopus 로고    scopus 로고
    • Medical problems of adult Turner's syndrome
    • Gravholt CH. 2001. Medical problems of adult Turner's syndrome. Horm Res 56(Suppl 1):44-50.
    • (2001) Horm Res , vol.56 , Issue.SUPPL. 1 , pp. 44-50
    • Gravholt, C.H.1
  • 27
    • 0036435120 scopus 로고    scopus 로고
    • Sexual dimorphism in the spontaneous recovery from spinal cord injury: A gender gap in beneficial autoimmunity?
    • Hauben E, Mizrahi T, Agranov E, Schwartz M. 2002. Sexual dimorphism in the spontaneous recovery from spinal cord injury: a gender gap in beneficial autoimmunity? Eur J Neurosci 16:1731-1740.
    • (2002) Eur J Neurosci , vol.16 , pp. 1731-1740
    • Hauben, E.1    Mizrahi, T.2    Agranov, E.3    Schwartz, M.4
  • 28
    • 0033888523 scopus 로고    scopus 로고
    • Timing of prenatal androgen exposure: Anatomical and endocrine effects on juvenile male and female rhesus monkeys
    • DOI 10.1006/hbeh.2000.1608
    • Herman RA, Jones B, Mann DR, Wallen K. 2000. Timing of prenatal androgen exposure: anatomical and endocrine effects on juvenile male and female rhesus monkeys. Horm Behav 38:52-66. (Pubitemid 30626783)
    • (2000) Hormones and Behavior , vol.38 , Issue.1 , pp. 52-66
    • Herman, R.A.1    Jones, B.2    Mann, D.R.3    Wallen, K.4
  • 29
    • 0042787557 scopus 로고    scopus 로고
    • Testosterone and gonadotropin levels in men with dementia
    • PII N24340309
    • Hogervorst E, Combrinck M, Smith AD. 2003. Testosterone and gonadotropin levels in men with dementia. Neuroendocrinol Lett 24:203-208. (Pubitemid 37074814)
    • (2003) Neuroendocrinology Letters , vol.24 , Issue.3-4 , pp. 203-208
    • Hogervorst, E.1    Combrinck, M.2    Smith, A.D.3
  • 30
    • 9644267082 scopus 로고    scopus 로고
    • Low free testosterone is an independent risk factor for Alzheimer's disease
    • DOI 10.1016/j.exger.2004.06.019, PII S0531556504002785
    • Hogervorst E, Bandelow S, Combrinck M, Smith AD. 2004. Low free testosterone is an independent risk factor for Alzheimer's disease. Exp Gerontol 39:1633-1639. (Pubitemid 39576135)
    • (2004) Experimental Gerontology , vol.39 , Issue.11-12 SPEC. ISS , pp. 1633-1639
    • Hogervorst, E.1    Bandelow, S.2    Combrinck, M.3    Smith, A.D.4
  • 31
  • 33
    • 0028001087 scopus 로고
    • Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon
    • DOI 10.1038/ng0894-536
    • Issa JP, Ottaviano YL, Celano P, Hamilton SR, Davidson NE, Baylin SB. 1994. Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon. Nat Genet 7:536-540. (Pubitemid 24308343)
    • (1994) Nature Genetics , vol.7 , Issue.4 , pp. 536-540
    • Issa, J.-P.J.1    Ottaviano, Y.L.2    Celano, P.3    Hamilton, S.R.4    Davidson, N.E.5    Baylin, S.B.6
  • 34
    • 72849131622 scopus 로고    scopus 로고
    • Sex differences in molecular neuroscience: From fruit flies to humans
    • Jazin E, Cahill L. 2010. Sex differences in molecular neuroscience: from fruit flies to humans. Nat Rev Neurosci 11:9-17.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 9-17
    • Jazin, E.1    Cahill, L.2
  • 35
    • 33847071714 scopus 로고    scopus 로고
    • Sex and the pathogenesis of cerebral palsy
    • Johnston MV, Hagberg H. 2007. Sex and the pathogenesis of cerebral palsy. Dev Med Child Neurol 49:74-78.
    • (2007) Dev Med Child Neurol , vol.49 , pp. 74-78
    • Johnston, M.V.1    Hagberg, H.2
  • 36
    • 49549091386 scopus 로고    scopus 로고
    • Contribution of gender-specific genetic factors to osteoporosis risk
    • Karasik D, Ferrari SL. 2008. Contribution of gender-specific genetic factors to osteoporosis risk. Ann Hum Genet 72:696-714.
    • (2008) Ann Hum Genet , vol.72 , pp. 696-714
    • Karasik, D.1    Ferrari, S.L.2
  • 38
    • 75749106276 scopus 로고    scopus 로고
    • Histological study of gender differences in accumulation of silver nanoparticles in kidneys of Fischer 344 rats
    • Kim WY, Kim J, Park JD, Ryu HY, Yu IJ. 2009. Histological study of gender differences in accumulation of silver nanoparticles in kidneys of Fischer 344 rats. J Toxicol Environ Health A 72:1279-1284.
    • (2009) J Toxicol Environ Health A , vol.72 , pp. 1279-1284
    • Kim, W.Y.1    Kim, J.2    Park, J.D.3    Ryu, H.Y.4    Yu, I.J.5
  • 39
    • 70349751728 scopus 로고    scopus 로고
    • Central role of TRAF-interacting protein in a new model of brain sexual differentiation
    • Krishnan S, Intlekofer KA, Aggison LK, Petersen SL. 2009. Central role of TRAF-interacting protein in a new model of brain sexual differentiation. Proc Natl Acad Sci U S A 106:16692-16697.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 16692-16697
    • Krishnan, S.1    Intlekofer, K.A.2    Aggison, L.K.3    Petersen, S.L.4
  • 40
    • 34848857092 scopus 로고    scopus 로고
    • Minocycline treatment in acute stroke: An open-label, evaluator-blinded study
    • DOI 10.1212/01.wnl.0000277487.04281.db, PII 0000611420071002000005
    • Lampl Y, Boaz M, Gilad R, Lorberboym M, Dabby R, Rapoport A, Anca-Hershkowitz M, Sadeh M. 2007. Minocycline treatment in acute stroke: an open-label, evaluator-blinded study. Neurology 69:1404-1410. (Pubitemid 47511461)
    • (2007) Neurology , vol.69 , Issue.14 , pp. 1404-1410
    • Lampl, Y.1    Boaz, M.2    Gilad, R.3    Lorberboym, M.4    Dabby, R.5    Rapoport, A.6    Anca-Hershkowitz, M.7    Sadeh, M.8
  • 41
    • 47749128919 scopus 로고    scopus 로고
    • Pathways to ischemic neuronal cell death: Are sex differences relevant?
    • Lang JT, McCullough LD. 2008. Pathways to ischemic neuronal cell death: are sex differences relevant? J Transl Med 6:33.
    • (2008) J Transl Med , vol.6 , pp. 33
    • Lang, J.T.1    McCullough, L.D.2
  • 43
    • 33750533592 scopus 로고    scopus 로고
    • Epigenetic regulation of nuclear steroid receptors
    • DOI 10.1016/j.bcp.2006.05.024, PII S0006295206003285, Cell Signalling, Transcription and Translation as Therapeutic Tergets
    • Leader JE, Wang C, Fu M, Pestell RG. 2006. Epigenetic regulation of nuclear steroid receptors. Biochem Pharmacol 72:1589-1596. (Pubitemid 44666731)
    • (2006) Biochemical Pharmacology , vol.72 , Issue.11 , pp. 1589-1596
    • Leader, J.E.1    Wang, C.2    Fu, M.3    Pestell, R.G.4
  • 44
    • 63949083605 scopus 로고    scopus 로고
    • Sex differences in minocycline-induced neuroprotection after experimental stroke
    • Li J, McCullough LD. 2009. Sex differences in minocycline-induced neuroprotection after experimental stroke. J Cereb Blood Flow Metab 29:670-674.
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 670-674
    • Li, J.1    McCullough, L.D.2
  • 45
    • 33747885367 scopus 로고    scopus 로고
    • The poly(ADP-ribose) polymerase 1 interacts with Sry and modulates its biological functions
    • DOI 10.1016/j.mce.2006.06.008, PII S0303720706003248
    • Li Y, Oh HJ, Lau YF. 2006. The poly(ADP-ribose) polymerase 1 interacts with Sry and modulates its biological functions. Mol Cell Endocrinol 257/258:35-46. (Pubitemid 44292418)
    • (2006) Molecular and Cellular Endocrinology , vol.257-258 , pp. 35-46
    • Li, Y.1    Oh, H.J.2    Lau, Y.-F.C.3
  • 46
    • 68749086071 scopus 로고    scopus 로고
    • Sex differences in the effects of acute and chronic stress and recovery after long-term stress on stress-related brain regions of rats
    • Lin Y, Ter Horst GJ, Wichmann R, Bakker P, Liu A, Li X, Westenbroek C. 2009. Sex differences in the effects of acute and chronic stress and recovery after long-term stress on stress-related brain regions of rats. Cereb Cortex 19:1978-1989.
    • (2009) Cereb Cortex , vol.19 , pp. 1978-1989
    • Lin, Y.1    Ter Horst, G.J.2    Wichmann, R.3    Bakker, P.4    Liu, A.5    Li, X.6    Westenbroek, C.7
  • 51
    • 0038268485 scopus 로고    scopus 로고
    • Estrogen and ischemic neuroprotection: An integrated view
    • McCullough LD, Hurn PD. 2003. Estrogen and ischemic neuroprotection: an integrated view. Trends Endocrinol Metab 14:228-235.
    • (2003) Trends Endocrinol Metab , vol.14 , pp. 228-235
    • McCullough, L.D.1    Hurn, P.D.2
  • 52
    • 0141535178 scopus 로고    scopus 로고
    • Aromatase cytochrome P450 and extragonadal estrogen play a role in ischemic neuroprotection
    • McCullough LD, Blizzard K, Simpson ER, Oz OK, Hurn PD. 2003. Aromatase cytochrome P450 and extragonadal estrogen play a role in ischemic neuroprotection. J Neurosci 23:8701-8705. (Pubitemid 37176650)
    • (2003) Journal of Neuroscience , vol.23 , Issue.25 , pp. 8701-8705
    • McCullough, L.D.1    Blizzard, K.2    Simpson, E.R.3    Oz, O.K.4    Hurn, P.D.5
  • 53
    • 17044430692 scopus 로고    scopus 로고
    • Ischemic nitric oxide and poly(ADP-ribose) polymerase-1 in cerebral ischemia: Male toxicity, female protection
    • McCullough LD, Zeng Z, Blizzard KK, Debchoudhury I, Hurn PD. 2005. Ischemic nitric oxide and poly(ADP-ribose) polymerase-1 in cerebral ischemia: male toxicity, female protection. J Cereb Blood Flow Metab 25:502-512.
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 502-512
    • McCullough, L.D.1    Zeng, Z.2    Blizzard, K.K.3    Debchoudhury, I.4    Hurn, P.D.5
  • 54
    • 34547842802 scopus 로고    scopus 로고
    • Why females are mosaics, X-chromosome inactivation, and sex differences in disease
    • Migeon BR. 2007. Why females are mosaics, X-chromosome inactivation, and sex differences in disease. Gender Med 4:97-105.
    • (2007) Gender Med , vol.4 , pp. 97-105
    • Migeon, B.R.1
  • 55
    • 63549150780 scopus 로고    scopus 로고
    • Activational and organisational effects of gonadal steroids on sex-specific acetylcholine release in the dorsal hippocampus
    • Mitsushima D, Takase K, Takahashi T, Kimura F. 2009. Activational and organisational effects of gonadal steroids on sex-specific acetylcholine release in the dorsal hippocampus. J Neuroendocrinol 21:400-405.
    • (2009) J Neuroendocrinol , vol.21 , pp. 400-405
    • Mitsushima, D.1    Takase, K.2    Takahashi, T.3    Kimura, F.4
  • 56
    • 47849098033 scopus 로고    scopus 로고
    • Estrogen and SERM neuroprotection in animal models of Parkinson's disease
    • Morissette M, Al Sweidi S, Callier S, Di Paolo T. 2008. Estrogen and SERM neuroprotection in animal models of Parkinson's disease. Mol Cell Endocrinol 290:60-69.
    • (2008) Mol Cell Endocrinol , vol.290 , pp. 60-69
    • Morissette, M.1    Al Sweidi, S.2    Callier, S.3    Di Paolo, T.4
  • 58
    • 63849107960 scopus 로고    scopus 로고
    • Gender and sex hormones in multiple sclerosis pathology and therapy
    • Nicot A. 2009. Gender and sex hormones in multiple sclerosis pathology and therapy. Front Biosci 14:4477-4515.
    • (2009) Front Biosci , vol.14 , pp. 4477-4515
    • Nicot, A.1
  • 59
    • 34548324512 scopus 로고    scopus 로고
    • Gender-dependent pathways of hypoxia-ischemia-induced cell death and neuroprotection in the immature P3 rat
    • Nijboer CH, Kavelaars A, van Bel F, Heijnen CJ, Groenendaal F. 2007. Gender-dependent pathways of hypoxia-ischemia-induced cell death and neuroprotection in the immature P3 rat. Dev Neurosci 29:385-392.
    • (2007) Dev Neurosci , vol.29 , pp. 385-392
    • Nijboer, C.H.1    Kavelaars, A.2    Van Bel, F.3    Heijnen, C.J.4    Groenendaal, F.5
  • 61
    • 41149164082 scopus 로고    scopus 로고
    • Androgens predispose males to GABAA-mediated excitotoxicity in the developing hippocampus
    • Nunez JL, McCarthy MM. 2008. Androgens predispose males to GABAA-mediated excitotoxicity in the developing hippocampus. Exp Neurol 210:699-708.
    • (2008) Exp Neurol , vol.210 , pp. 699-708
    • Nunez, J.L.1    McCarthy, M.M.2
  • 62
    • 0028318783 scopus 로고
    • Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells
    • Ottaviano YL, Issa JP, Parl FF, Smith HS, Baylin SB, Davidson NE. 1994. Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells. Cancer Res 54:2552-2555.
    • (1994) Cancer Res , vol.54 , pp. 2552-2555
    • Ottaviano, Y.L.1    Issa, J.P.2    Parl, F.F.3    Smith, H.S.4    Baylin, S.B.5    Davidson, N.E.6
  • 63
    • 10644228454 scopus 로고    scopus 로고
    • Testosterone is responsible for enhanced susceptibility of males to ischemic renal injury
    • DOI 10.1074/jbc.M407629200
    • Park KM, Kim JI, Ahn Y, Bonventre AJ, Bonventre JV. 2004. Testosterone is responsible for enhanced susceptibility of males to ischemic renal injury. J Biol Chem 279:52282-52292. (Pubitemid 39656602)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.50 , pp. 52282-52292
    • Park, K.M.1    Kim, J.I.2    Ahn, Y.3    Bonventre, A.J.4    Bonventre, J.V.5
  • 65
    • 59749090040 scopus 로고    scopus 로고
    • Osteoporosis: An age-related and gender-specific disease - A mini-review
    • Pietschmann P, Rauner M, Sipos W, Kerschan-Schindl K. 2009. Osteoporosis: an age-related and gender-specific disease - a mini-review. Gerontology 55:3-12.
    • (2009) Gerontology , vol.55 , pp. 3-12
    • Pietschmann, P.1    Rauner, M.2    Sipos, W.3    Kerschan-Schindl, K.4
  • 67
    • 70350059677 scopus 로고    scopus 로고
    • Postischemic treatment of neonatal cerebral ischemia should target autophagy
    • Puyal J, Vaslin A, Mottier V, Clarke PG. 2009. Postischemic treatment of neonatal cerebral ischemia should target autophagy. Ann Neurol 66:378-389.
    • (2009) Ann Neurol , vol.66 , pp. 378-389
    • Puyal, J.1    Vaslin, A.2    Mottier, V.3    Clarke, P.G.4
  • 72
    • 67649649620 scopus 로고    scopus 로고
    • Brain aromatization: Classic roles and new perspectives
    • Roselli CE, Liu M, Hurn PD. 2009. Brain aromatization: classic roles and new perspectives. Semin Reprod Med 27:207-217.
    • (2009) Semin Reprod Med , vol.27 , pp. 207-217
    • Roselli, C.E.1    Liu, M.2    Hurn, P.D.3
  • 73
    • 0032916572 scopus 로고    scopus 로고
    • Sex differences in the effects of early neocortical injury on neuronal size distribution of the medial geniculate nucleus in the rat are mediated by perinatal gonadal steroids
    • Rosen GD, Herman AE, Galaburda AM. 1999. Sex differences in the effects of early neocortical injury on neuronal size distribution of the medial geniculate nucleus in the rat are mediated by perinatal gonadal steroids. Cereb Cortex 9:27-34.
    • (1999) Cereb Cortex , vol.9 , pp. 27-34
    • Rosen, G.D.1    Herman, A.E.2    Galaburda, A.M.3
  • 77
    • 8344242220 scopus 로고    scopus 로고
    • Autophagy in health and disease: A double-edged sword
    • DOI 10.1126/science.1099993
    • Shintani T, Klionsky DJ. 2004. Autophagy in health and disease: a double-edged sword. Science 306:990-995. (Pubitemid 39482894)
    • (2004) Science , vol.306 , Issue.5698 , pp. 990-995
    • Shintani, T.1    Klionsky, D.J.2
  • 80
    • 61449191655 scopus 로고    scopus 로고
    • Cutting edge: The Y chromosome controls the age-dependent experimental allergic encephalomyelitis sexual dimorphism in SJL/J mice
    • Spach KM, Blake M, Bunn JY, McElvany B, Noubade R, Blankenhorn EP, Teuscher C. 2009. Cutting edge: the Y chromosome controls the age-dependent experimental allergic encephalomyelitis sexual dimorphism in SJL/J mice. J Immunol 182:1789-1793.
    • (2009) J Immunol , vol.182 , pp. 1789-1793
    • Spach, K.M.1    Blake, M.2    Bunn, J.Y.3    McElvany, B.4    Noubade, R.5    Blankenhorn, E.P.6    Teuscher, C.7
  • 81
    • 64649104206 scopus 로고    scopus 로고
    • Sex differences in histone modifications in the neonatal mouse brain
    • Tsai HW, Grant PA, Rissman EF. 2009. Sex differences in histone modifications in the neonatal mouse brain. Epigenetics 4:47-53.
    • (2009) Epigenetics , vol.4 , pp. 47-53
    • Tsai, H.W.1    Grant, P.A.2    Rissman, E.F.3
  • 85
    • 73549097074 scopus 로고    scopus 로고
    • Gender differences in pediatric stroke: Is elevated testosterone a risk factor for boys?
    • Vannucci SJ, Hurn PD. 2009. Gender differences in pediatric stroke: is elevated testosterone a risk factor for boys? Ann Neurol 66:713-714.
    • (2009) Ann Neurol , vol.66 , pp. 713-714
    • Vannucci, S.J.1    Hurn, P.D.2
  • 88
    • 41549151941 scopus 로고    scopus 로고
    • Epigenetic regulation of the estrogen receptor alpha promoter in the cerebral cortex following ischemia in male and female rats
    • Westberry JM, Prewitt AK, Wilson ME. 2008. Epigenetic regulation of the estrogen receptor alpha promoter in the cerebral cortex following ischemia in male and female rats. Neuroscience 152:982-989.
    • (2008) Neuroscience , vol.152 , pp. 982-989
    • Westberry, J.M.1    Prewitt, A.K.2    Wilson, M.E.3
  • 89
    • 74949100523 scopus 로고    scopus 로고
    • Epigenetic regulation of estrogen receptor alpha gene expression in the mouse cortex during early postnatal development
    • Westberry JM, Trout AL, Wilson ME. 2010. Epigenetic regulation of estrogen receptor alpha gene expression in the mouse cortex during early postnatal development. Endocrinology 151:731-740.
    • (2010) Endocrinology , vol.151 , pp. 731-740
    • Westberry, J.M.1    Trout, A.L.2    Wilson, M.E.3
  • 91
    • 43049164272 scopus 로고    scopus 로고
    • Dynamic regulation of estrogen receptor-alpha gene expression in the brain: A role for promoter methylation?
    • Wilson ME, Westberry JM, Prewitt AK. 2008. Dynamic regulation of estrogen receptor-alpha gene expression in the brain: a role for promoter methylation? Front Neuroendocrinol 29:375-385.
    • (2008) Front Neuroendocrinol , vol.29 , pp. 375-385
    • Wilson, M.E.1    Westberry, J.M.2    Prewitt, A.K.3
  • 92
    • 27144491937 scopus 로고    scopus 로고
    • Estimated risk score for spine fracture in the specific bending activity of normal Taiwanese men and women
    • Yang RS, Lin HJ, Chieng PU, Liu TK, Tsai KS. 2005. Estimated risk score for spine fracture in the specific bending activity of normal Taiwanese men and women. Spine 30:2288-2292.
    • (2005) Spine , vol.30 , pp. 2288-2292
    • Yang, R.S.1    Lin, H.J.2    Chieng, P.U.3    Liu, T.K.4    Tsai, K.S.5
  • 94
    • 64249104435 scopus 로고    scopus 로고
    • Sex differences in the response to activation of the poly (ADP-ribose) polymerase pathway after experimental stroke
    • Yuan M, Siegel C, Zeng Z, Li J, Liu F, McCullough LD. 2009. Sex differences in the response to activation of the poly (ADP-ribose) polymerase pathway after experimental stroke. Exp Neurol 217:210-218.
    • (2009) Exp Neurol , vol.217 , pp. 210-218
    • Yuan, M.1    Siegel, C.2    Zeng, Z.3    Li, J.4    Liu, F.5    McCullough, L.D.6
  • 95
    • 33645100937 scopus 로고    scopus 로고
    • Different apoptotic mechanisms are activated in male and female brains after neonatal hypoxia-ischaemia
    • Zhu C, Xu F, Wang X, Shibata M, Uchiyama Y, Blomgren K, Hagberg H. 2006. Different apoptotic mechanisms are activated in male and female brains after neonatal hypoxia-ischaemia. J Neurochem 96:1016-1027.
    • (2006) J Neurochem , vol.96 , pp. 1016-1027
    • Zhu, C.1    Xu, F.2    Wang, X.3    Shibata, M.4    Uchiyama, Y.5    Blomgren, K.6    Hagberg, H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.