Enhanced poly(ADP-ribosyl)ation after focal ischemia in rat brain

Journal of Cerebral Blood Flow and Metabolism

Volumn 18, Issue 9, 1998, Pages 991-997

  Tokime, Tomoo ^a   Nozaki, Kazuhiko ^a   Sugino, Toshiyuki ^a   Kikuchi, Haruhiko ^a   Hashimoto, Nobuo ^a   Ueda, Kunihiro ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Focal ischemia; Nitric oxide; Poly(ADP ribose) polymerase 3 Aminobenzamide; Poly(ADP ribosyl)ation; Rat

Indexed keywords

3 AMINOBENZAMIDE; NITRIC OXIDE;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INFARCTION; BRAIN ISCHEMIA; CELL DEATH; CONTROLLED STUDY; DNA DAMAGE; IMMUNOHISTOCHEMISTRY; MIDDLE CEREBRAL ARTERY OCCLUSION; MITOCHONDRIAL RESPIRATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0031723465     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-199809000-00008     Document Type: Article

References (19)

1. Burkart V, Groß-Eick A, Bellmann K, Radons J, Kollb H (1995) Suppression of nitric oxide toxicity in islet cells by α-tocopherol. FEBS Lett 364:259-263
2. Bederson JB, Pitts LH, Gernard SM, Nishimura MC, Davis RL, Bartokowski HM (1986) Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats. Stroke 17:1304-1308
3. Cosi C, Suzuki H, Milani D, Facci L, Menegazzi M, Vantini G, Kanai Y, Skaper SD (1994) Poly(ADP-ribose) polymerase: early involvement in glutamate-induced neurotoxicity in cultured cerebellar granule cells. J Neurosci Res 39:38-46
4. de Murcia G, de Murcia JM (1994) Poly(ADP-ribose) polymerase: a molecular nick sensor. TIBS 19:172-176
5. Eliasson MJL, Sampei K, Mandir AS, Hum PD, Traystman RJ, Bao J, Pieper A, Wang ZO, Dawson TM, Snyder SH, Dawson VL (1997) Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia. Nature Med 3:1089-1095
6. Heller B, Wang Z, Wagner EF, Radons J, Burkle A, Fehsel K, Burkart V, Kolb H (1995) Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells. J Biol Chem 270:11176-11180
7. Huang Z, Huang PL, Panahian N, Dalkara T, Fishman MC, Moskowitz MA (1994) Effect of cerebral ischemia in mice deficient in neuronal nitric oxide synthase. Science 265:1883-1885
8. Iadecola C, Pelligrino DA, Moskowitz MA, Lassen NA (1994) Nitric oxide synthase inhibition and cerebrovascular regulation. J Cereb Blood Flow Metab 14:175-192
9. Ikai K, Ueda K, Hayaishi O (1980) Immunohistochemical demonstration of poly(adenosine diphosphate-ribose) in nuclei of various rat tissues. J Histochem Cytochem 28:670-676
10. Kuo M, Chau Y, Wang J, Shiah S (1996) Inhibitors of poly(ADP-ribose) polymerase block nitric oxide-induced apoptosis but not differentiation in human leukemia HL-60 cells. Biochem Biophys Res Commun 219:502-508
11. Longa EZ, Weinstein PR, Carlson S, Cummins R (1989) Reversible middle cerebral artery occlusion without craniectomy in the rat. Stroke 20:84-91
12. Nosseri C, Coppola S, Ghibelli L (1992) Possible involvement of poly-(ADP-ribosyl) polymerase in triggering stress-induced apoptosis. Exp Cell Res 212:367-373
13. + depletion. Biochem Biophys Res Commun 199:1270-1277
14. Sugino T, Nozaki K, Tokime T, Hashimoto N, Kikuchi H (1997) 3-nitropropionic acid induces poly(ADP-ribosyl)ation and apoptosis related gene expression in the striatum in vivo. Neurosci Lett 237:1-4
15. Wink DA, Kasprazax KS, Maragos CH, Elespuru RK, Mirsa M, Dunams TM, Cebula TA, Koch WH, Andrews AW, Allen JS, Keefer LK (1991) DNA delaminating ability and genotoxicity of nitric oxide and its progenitors. Science 254:1001-1003
16. Yoshida T, Limmroth V, Irikura K, Moscowitz MA (1994) The NOS inhibitor 7-nitro indazole, decreases focal infarct volume but not the response to topical acetylcholine in pial vessels. J Cereb Blood Flow Metab 14:924-929
17. Zhang J, Dawson VL, Dawson TM, Snyder SH (1994) Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. Science 263:687-689
18. Zhang J, Pieper A, Snyder SH (1995) Poly(ADP-ribose) synthetase activation: An early indicator of neurotoxic DNA damage. J Neurochem 65:1411-1414
19. Zingarelli B, O'Conner M, Wong H, Salzman AL, Szabo C (1996) Peroxynitrite mediated DNA strand breakage activates polyadenosine diphosphate ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide. J Immunol 156:350-358