-
1
-
-
0035289536
-
Protective effects of PJ34, a novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP) in in vitro and in vivo models of stroke
-
Abdelkarim GE, Gertz K, Harms C, Katchanov J, Dirnagl U, Szabo C, Endres M (2001) Protective effects of PJ34, a novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP) in in vitro and in vivo models of stroke. Int J Mol Med 7:255-60
-
(2001)
Int J Mol Med
, vol.7
, pp. 255-260
-
-
Abdelkarim, G.E.1
Gertz, K.2
Harms, C.3
Katchanov, J.4
Dirnagl, U.5
Szabo, C.6
Endres, M.7
-
2
-
-
0031984050
-
Gender linked brain injury in experimental stroke
-
discussion 166
-
Alkayed NJ, Harukuni I, Kimes AS, London ED, Traystman RJ, Hurn PD (1998) Gender linked brain injury in experimental stroke. Stroke 29:159-65; discussion 166
-
(1998)
Stroke
, vol.29
, pp. 159-165
-
-
Alkayed, N.J.1
Harukuni, I.2
Kimes, A.S.3
London, E.D.4
Traystman, R.J.5
Hurn, P.D.6
-
3
-
-
0032777665
-
Endothelium-derived nitric oxide and vascular physiology and pathology
-
Arnal JF, Dinh-Xuan AT, Pueyo M, Darblade B, Rami J (1999) Endothelium-derived nitric oxide and vascular physiology and pathology. Cell Mol Life Sci 55:1078-87
-
(1999)
Cell Mol Life Sci
, vol.55
, pp. 1078-1087
-
-
Arnal, J.F.1
Dinh-Xuan, A.T.2
Pueyo, M.3
Darblade, B.4
Rami, J.5
-
4
-
-
0028584148
-
Reactions of nitric oxide, superoxide and peroxynitrite with superoxide dismutase in neurodegeneration
-
Beckman JS, Chen J, Crow JP, Ye YZ (1994) Reactions of nitric oxide, superoxide and peroxynitrite with superoxide dismutase in neurodegeneration. Prog Brain Res 103:371-80
-
(1994)
Prog Brain Res
, vol.103
, pp. 371-380
-
-
Beckman, J.S.1
Chen, J.2
Crow, J.P.3
Ye, Y.Z.4
-
5
-
-
0029805172
-
Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly
-
Beckman JS, Koppenol WH (1996) Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol 271:C1424-C37
-
(1996)
Am J Physiol
, vol.271
-
-
Beckman, J.S.1
Koppenol, W.H.2
-
6
-
-
0037634342
-
Functional implications of antiestrogen induction of quinone reductase: Inhibition of estrogen-induced deoxyribonucleic acid damage
-
Bianco NR, Perry G, Smith MA, Templeton DJ, Montano MM (2003) Functional implications of antiestrogen induction of quinone reductase: inhibition of estrogen-induced deoxyribonucleic acid damage. Mol Endocrinol 17:1344-55
-
(2003)
Mol Endocrinol
, vol.17
, pp. 1344-1355
-
-
Bianco, N.R.1
Perry, G.2
Smith, M.A.3
Templeton, D.J.4
Montano, M.M.5
-
7
-
-
0033956280
-
Estrogen status affects sensitivity to focal cerebral ischemia in stroke-prone spontaneously hypertensive rats
-
Carswell HV, Dominiczak AF, Macrae IM (2000) Estrogen status affects sensitivity to focal cerebral ischemia in stroke-prone spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol 278:H290-H4
-
(2000)
Am J Physiol Heart Circ Physiol
, vol.278
-
-
Carswell, H.V.1
Dominiczak, A.F.2
Macrae, I.M.3
-
8
-
-
0036798936
-
Estrogen modulation of endothelial nitric oxide synthase
-
Chambliss KL, Shaul PW (2002) Estrogen modulation of endothelial nitric oxide synthase. Endocr Rev 23:665-86
-
(2002)
Endocr Rev
, vol.23
, pp. 665-686
-
-
Chambliss, K.L.1
Shaul, P.W.2
-
9
-
-
0141755305
-
T:G mismatch-specific thymine-DNA glycosylase potentiates transcription of estrogen-regulated genes through direct interaction with estrogen receptor alpha
-
Chen D, Lucey MJ, Phoenix F, Lopez-Garcia J, Hart SM, Losson R, Buluwela L, Coombes RC, Chambon P, Schar P, Ali S (2003) T:G mismatch-specific thymine-DNA glycosylase potentiates transcription of estrogen-regulated genes through direct interaction with estrogen receptor alpha. J Biol Chem 278:38586-92
-
(2003)
J Biol Chem
, vol.278
, pp. 38586-38592
-
-
Chen, D.1
Lucey, M.J.2
Phoenix, F.3
Lopez-Garcia, J.4
Hart, S.M.5
Losson, R.6
Buluwela, L.7
Coombes, R.C.8
Chambon, P.9
Schar, P.10
Ali, S.11
-
10
-
-
0032699638
-
Increased mitochondrial superoxide production in rat liver mitochondria, rat hepatocytes, and HepG2 cells following ethinyl estradiol treatment
-
Chen J, Li Y, Lavigne JA, Trush MA, Yager JD (1999) Increased mitochondrial superoxide production in rat liver mitochondria, rat hepatocytes, and HepG2 cells following ethinyl estradiol treatment. Toxicol Sci 51:224-35
-
(1999)
Toxicol Sci
, vol.51
, pp. 224-235
-
-
Chen, J.1
Li, Y.2
Lavigne, J.A.3
Trush, M.A.4
Yager, J.D.5
-
11
-
-
0032961726
-
A comparative study of the effects of two nitric oxide synthase inhibitors and two nitric oxide donors on temporary focal cerebral ischemia in the Wistar rat
-
Coert BA, Anderson RE, Meyer FB (1999) A comparative study of the effects of two nitric oxide synthase inhibitors and two nitric oxide donors on temporary focal cerebral ischemia in the Wistar rat. J Neurosurg 90:332-8
-
(1999)
J Neurosurg
, vol.90
, pp. 332-338
-
-
Coert, B.A.1
Anderson, R.E.2
Meyer, F.B.3
-
12
-
-
0037235022
-
Is neuroprotective efficacy of nNOS inhibitor 7-NI dependent on ischemic intracellular pH?
-
Coert BA, Anderson RE, Meyer FB (2003) Is neuroprotective efficacy of nNOS inhibitor 7-NI dependent on ischemic intracellular pH? Am J Physiol Heart Circ Physiol 284:H151-H9
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.284
-
-
Coert, B.A.1
Anderson, R.E.2
Meyer, F.B.3
-
14
-
-
0029927787
-
Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice
-
Dawson VL, Kizushi VM, Huang PL, Snyder SH, Dawson TM (1996) Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice. J Neurosci 16:2479-87
-
(1996)
J Neurosci
, vol.16
, pp. 2479-2487
-
-
Dawson, V.L.1
Kizushi, V.M.2
Huang, P.L.3
Snyder, S.H.4
Dawson, T.M.5
-
16
-
-
0040984333
-
Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells
-
de Murcia JM, Niedergang C, Trucco C, Ricoul M, Dutrillaux B, Mark M, Oliver FJ, Masson M, Dierich A, LeMeur M, Walztinger C, Chambon P, de Murcia G (1997) Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells. Proc Natl Acad Sci USA 94:7303-7
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 7303-7307
-
-
De Murcia, J.M.1
Niedergang, C.2
Trucco, C.3
Ricoul, M.4
Dutrillaux, B.5
Mark, M.6
Oliver, F.J.7
Masson, M.8
Dierich, A.9
LeMeur, M.10
Walztinger, C.11
Chambon, P.12
De Murcia, G.13
-
17
-
-
0034698284
-
Phosphorylation of the endothelial nitric oxide synthase at ser-1177 is required for VEGF-induced endothelial cell migration
-
Dimmeler S, Dernbach E, Zeiher AM (2000) Phosphorylation of the endothelial nitric oxide synthase at ser-1177 is required for VEGF-induced endothelial cell migration. FEBS Lett 477:258-62
-
(2000)
FEBS Lett
, vol.477
, pp. 258-262
-
-
Dimmeler, S.1
Dernbach, E.2
Zeiher, A.M.3
-
18
-
-
4644305774
-
Innate gender-based proclivity in response to cytotoxicity and programmed cell death pathway
-
Du L, Bayir H, Lai Y, Zhang X, Kochanek PM, Watkins SC, Graham SH, Clark RS (2004) Innate gender-based proclivity in response to cytotoxicity and programmed cell death pathway. J Biol Chem 297:38563-70
-
(2004)
J Biol Chem
, vol.297
, pp. 38563-38570
-
-
Du, L.1
Bayir, H.2
Lai, Y.3
Zhang, X.4
Kochanek, P.M.5
Watkins, S.C.6
Graham, S.H.7
Clark, R.S.8
-
19
-
-
0038043242
-
Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress
-
Du L, Zhang X, Han YY, Burke NA, Kochanek PM, Watkins SC, Graham SH, Carcillo JA, Szabo C, Clark RS (2003) Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress. J Biol Chem 278:18426-33
-
(2003)
J Biol Chem
, vol.278
, pp. 18426-18433
-
-
Du, L.1
Zhang, X.2
Han, Y.Y.3
Burke, N.A.4
Kochanek, P.M.5
Watkins, S.C.6
Graham, S.H.7
Carcillo, J.A.8
Szabo, C.9
Clark, R.S.10
-
20
-
-
0035852657
-
Estrogen receptor alpha, not beta, is a critical link in estradiol-mediated protection against brain injury
-
Dubai DB, Zhu H, Yu J, Rau SW, Shughrue PJ, Merchenthaler I, Kindy MS, Wise PM (2001) Estrogen receptor alpha, not beta, is a critical link in estradiol-mediated protection against brain injury. Proc Natl Acad Sci USA 98:1952-7
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 1952-1957
-
-
Dubai, D.B.1
Zhu, H.2
Yu, J.3
Rau, S.W.4
Shughrue, P.J.5
Merchenthaler, I.6
Kindy, M.S.7
Wise, P.M.8
-
21
-
-
0030842946
-
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia
-
Eliasson MJ, Sampei K, Mandir AS, Hurn PD, Traystman RJ, Bao J, Pieper A, Wang ZQ, Dawson TM, Snyder SH, Dawson VL (1997) Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia. Nat Med 3:1089-95
-
(1997)
Nat Med
, vol.3
, pp. 1089-1095
-
-
Eliasson, M.J.1
Sampei, K.2
Mandir, A.S.3
Hurn, P.D.4
Traystman, R.J.5
Bao, J.6
Pieper, A.7
Wang, Z.Q.8
Dawson, T.M.9
Snyder, S.H.10
Dawson, V.L.11
-
22
-
-
0030832874
-
Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase
-
Endres M, Wang ZQ, Namura S, Waeber C, Moskowitz MA (1997) Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase. J Cereb Blood Flow Metab 17:1143-51
-
(1997)
J Cereb Blood Flow Metab
, vol.17
, pp. 1143-1151
-
-
Endres, M.1
Wang, Z.Q.2
Namura, S.3
Waeber, C.4
Moskowitz, M.A.5
-
23
-
-
0032557410
-
Role of peroxynitrite and neuronal nitric oxide synthase in the activation of poly(ADP-ribose) synthetase in a murine model of cerebral ischemia-reperfusion
-
Endres M, Scott G, Namura S, Salzman AL, Huang PL, Moskowitz MA, Szabo C (1998) Role of peroxynitrite and neuronal nitric oxide synthase in the activation of poly(ADP-ribose) synthetase in a murine model of cerebral ischemia-reperfusion. Neurosci Lett 248:41-4
-
(1998)
Neurosci Lett
, vol.248
, pp. 41-44
-
-
Endres, M.1
Scott, G.2
Namura, S.3
Salzman, A.L.4
Huang, P.L.5
Moskowitz, M.A.6
Szabo, C.7
-
24
-
-
0035136240
-
Diabetic endothelial dysfunction: The role of poly(ADP-ribose) polymerase activation
-
Garcia Soriano F, Virag L, Jagtap P, Szabo E, Mabley JG, Liaudet L, Marton A, Hoyt DG, Murthy KG, Salzman AL, Southan GJ, Szabo C (2001) Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation. Nat Med 7:108-13
-
(2001)
Nat Med
, vol.7
, pp. 108-113
-
-
Garcia Soriano, F.1
Virag, L.2
Jagtap, P.3
Szabo, E.4
Mabley, J.G.5
Liaudet, L.6
Marton, A.7
Hoyt, D.G.8
Murthy, K.G.9
Salzman, A.L.10
Southan, G.J.11
Szabo, C.12
-
25
-
-
0344771013
-
Estrogen stimulates neuronal nitric oxide synthase protein expression in human neutrophils
-
Garcia-Duran M, de Frutos T, Diaz-Recasens J, Garcia-Galvez G, Jimenez A, Monton M, Farre J, Sanchez de Miguel L, Gonzalez-Fernandez F, Arriero MD, Rico L, Garcia R, Casado S, Lopez-Farre A (1999) Estrogen stimulates neuronal nitric oxide synthase protein expression in human neutrophils. Circ Res 85:1020-6
-
(1999)
Circ Res
, vol.85
, pp. 1020-1026
-
-
Garcia-Duran, M.1
De Frutos, T.2
Diaz-Recasens, J.3
Garcia-Galvez, G.4
Jimenez, A.5
Monton, M.6
Farre, J.7
Sanchez De Miguel, L.8
Gonzalez-Fernandez, F.9
Arriero, M.D.10
Rico, L.11
Garcia, R.12
Casado, S.13
Lopez-Farre, A.14
-
27
-
-
0036218940
-
Poly(ADP-ribose) polymerase impairs early and long-term experimental stroke recovery
-
Goto S, Xue R, Sugo N, Sawada M, Blizzard KK, Poitras MF, Johns DC, Dawson TM, Dawson VL, Crain BJ, Traystman RJ, Mori S, Hurn PD (2002) Poly(ADP-ribose) polymerase impairs early and long-term experimental stroke recovery. Stroke 33:1101-6
-
(2002)
Stroke
, vol.33
, pp. 1101-1106
-
-
Goto, S.1
Xue, R.2
Sugo, N.3
Sawada, M.4
Blizzard, K.K.5
Poitras, M.F.6
Johns, D.C.7
Dawson, T.M.8
Dawson, V.L.9
Crain, B.J.10
Traystman, R.J.11
Mori, S.12
Hurn, P.D.13
-
28
-
-
0034930737
-
Neuroprotective effect of sigma(1)-receptor ligand 4-phenyl-1-(4- phenylbutyl) piperidine (PPBP) is linked to reduced neuronal nitric oxide production
-
Goyagi T, Goto S, Bhardwaj A, Dawson VL, Hurn PD, Kirsch JR (2001) Neuroprotective effect of sigma(1)-receptor ligand 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) is linked to reduced neuronal nitric oxide production. Stroke 32:1613-20
-
(2001)
Stroke
, vol.32
, pp. 1613-1620
-
-
Goyagi, T.1
Goto, S.2
Bhardwaj, A.3
Dawson, V.L.4
Hurn, P.D.5
Kirsch, J.R.6
-
29
-
-
0031724393
-
A novel, synergistic interaction between 17 beta-estradiol and glutathione in the protection of neurons against beta-amyloid 25-35-induced toxicity in vitro
-
Gridley KE, Green PS, Simpkins JW (1998) A novel, synergistic interaction between 17 beta-estradiol and glutathione in the protection of neurons against beta-amyloid 25-35-induced toxicity in vitro. Mol Pharmacol 54:874-80
-
(1998)
Mol Pharmacol
, vol.54
, pp. 874-880
-
-
Gridley, K.E.1
Green, P.S.2
Simpkins, J.W.3
-
30
-
-
3042821104
-
17 Beta-estradiol regulates nNOS and eNOS activity in the hippocampus
-
Grohe C, Kann S, Fink L, Djoufack PC, Paehr M, van Eickels M, Vetter H, Meyer R, Fink KB (2004) 17 Beta-estradiol regulates nNOS and eNOS activity in the hippocampus. Neuroreport 15:89-93
-
(2004)
Neuroreport
, vol.15
, pp. 89-93
-
-
Grohe, C.1
Kann, S.2
Fink, L.3
Djoufack, P.C.4
Paehr, M.5
Van Eickels, M.6
Vetter, H.7
Meyer, R.8
Fink, K.B.9
-
31
-
-
0033830186
-
Poly(ADP-ribose) polymerase-1 in the nervous system
-
Ha HC, Snyder SH (2000) Poly(ADP-ribose) polymerase-1 in the nervous system. Neurobiol Dis 7:225-39
-
(2000)
Neurobiol Dis
, vol.7
, pp. 225-239
-
-
Ha, H.C.1
Snyder, S.H.2
-
32
-
-
4444383142
-
PARP-I gene disruption in mice preferentially protects males from perinatal brain injury
-
Hagberg H, Wilson MA, Matsushita H, Zhu C, Lange M, Gustavsson M, Poitras MF, Dawson TM, Dawson VL, Northington F, Johnston MV (2004) PARP-I gene disruption in mice preferentially protects males from perinatal brain injury. J Neurochem 90:1068-75
-
(2004)
J Neurochem
, vol.90
, pp. 1068-1075
-
-
Hagberg, H.1
Wilson, M.A.2
Matsushita, H.3
Zhu, C.4
Lange, M.5
Gustavsson, M.6
Poitras, M.F.7
Dawson, T.M.8
Dawson, V.L.9
Northington, F.10
Johnston, M.V.11
-
33
-
-
0030989927
-
Effect of estrogen on isoforms of nitric oxide synthase: Possible mechanism of anti-atherosclerotic effect of estrogen
-
Hayashi T, Yamada K, Esaki T, Mutoh E, Iguchi A (1997) Effect of estrogen on isoforms of nitric oxide synthase: possible mechanism of anti-atherosclerotic effect of estrogen. Gerontology 43(Suppl 1):24-34
-
(1997)
Gerontology
, vol.43
, Issue.SUPPL. 1
, pp. 24-34
-
-
Hayashi, T.1
Yamada, K.2
Esaki, T.3
Mutoh, E.4
Iguchi, A.5
-
34
-
-
2142694340
-
Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling
-
Hong SJ, Dawson TM, Dawson VL (2004) Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling. Trends Pharmacol Sci 25:259-64
-
(2004)
Trends Pharmacol Sci
, vol.25
, pp. 259-264
-
-
Hong, S.J.1
Dawson, T.M.2
Dawson, V.L.3
-
35
-
-
0027945658
-
Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase
-
Huang Z, Huang PL, Panahian N, Dalkara T, Fishman MC, Moskowitz MA (1994) Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase. Science 265:1883-5
-
(1994)
Science
, vol.265
, pp. 1883-1885
-
-
Huang, Z.1
Huang, P.L.2
Panahian, N.3
Dalkara, T.4
Fishman, M.C.5
Moskowitz, M.A.6
-
38
-
-
0035692992
-
Regional vulnerability after traumatic brain injury: Gender differences in mice that overexpress human copper, zinc superoxide dismutase
-
Igarashi T, Huang TT, Noble LJ (2001) Regional vulnerability after traumatic brain injury: gender differences in mice that overexpress human copper, zinc superoxide dismutase. Exp Neurol 172:332-41
-
(2001)
Exp Neurol
, vol.172
, pp. 332-341
-
-
Igarashi, T.1
Huang, T.T.2
Noble, L.J.3
-
39
-
-
17144447467
-
Novel phenanthridinone inhibitors of poly (adenosine 5′- diphosphate-ribose) synthetase: Potent cytoprotective and antishock agents
-
Jagtap P, Soriano FG, Virag L, Liaudet L, Mabley J, Szabo E, Hasko G, Marton A, Lorigados CB, Gallyas Jr F, Sumegi B, Hoyt DG, Baloglu E, VanDuzer J, Salzman AL, Southan GJ, Szabo C (2002) Novel phenanthridinone inhibitors of poly (adenosine 5′-diphosphate-ribose) synthetase: potent cytoprotective and antishock agents. Crit Care Med 30:1071-82
-
(2002)
Crit Care Med
, vol.30
, pp. 1071-1082
-
-
Jagtap, P.1
Soriano, F.G.2
Virag, L.3
Liaudet, L.4
Mabley, J.5
Szabo, E.6
Hasko, G.7
Marton, A.8
Lorigados, C.B.9
Gallyas Jr., F.10
Sumegi, B.11
Hoyt, D.G.12
Baloglu, E.13
VanDuzer, J.14
Salzman, A.L.15
Southan, G.J.16
Szabo, C.17
-
40
-
-
0029858401
-
Effects of nitric oxide synthase inhibition on brain infarction in SOD-1-transgenic mice following transient focal cerebral ischemia
-
Kamii H, Mikawa S, Murakami K, Kinouchi H, Yoshimoto T, Reola L, Carlson E, Epstein CJ, Chan PH (1996) Effects of nitric oxide synthase inhibition on brain infarction in SOD-1-transgenic mice following transient focal cerebral ischemia. J Cereb Blood Flow Metab 16:1153-7
-
(1996)
J Cereb Blood Flow Metab
, vol.16
, pp. 1153-1157
-
-
Kamii, H.1
Mikawa, S.2
Murakami, K.3
Kinouchi, H.4
Yoshimoto, T.5
Reola, L.6
Carlson, E.7
Epstein, C.J.8
Chan, P.H.9
-
41
-
-
17144434775
-
Poly(ADP-ribose) polymerase inhibition protect neurons and the white matter and regulates the translocation of apoptosis-inducing factor in stroke
-
Komjati K, Mabley JG, Virag L, Southan GJ, Salzman AL, Szabo C (2004) Poly(ADP-ribose) polymerase inhibition protect neurons and the white matter and regulates the translocation of apoptosis-inducing factor in stroke. Int J Mol Med 13:373-82
-
(2004)
Int J Mol Med
, vol.13
, pp. 373-382
-
-
Komjati, K.1
Mabley, J.G.2
Virag, L.3
Southan, G.J.4
Salzman, A.L.5
Szabo, C.6
-
43
-
-
0032563688
-
Estrogen-dependent modulation of rat brain ascorbate levels and ischemia-induced ascorbate loss
-
Kume-Kick J, Rice ME (1998) Estrogen-dependent modulation of rat brain ascorbate levels and ischemia-induced ascorbate loss. Brain Res 803:105-13
-
(1998)
Brain Res
, vol.803
, pp. 105-113
-
-
Kume-Kick, J.1
Rice, M.E.2
-
44
-
-
0034822090
-
Neonatal hypoxic risk in preterm birth infants: The influence of sex and severity of respiratory distress on cognitive recovery
-
Lauterbach MD, Raz S, Sander CJ (2001) Neonatal hypoxic risk in preterm birth infants: the influence of sex and severity of respiratory distress on cognitive recovery. Neuropsychology 15:411-20
-
(2001)
Neuropsychology
, vol.15
, pp. 411-420
-
-
Lauterbach, M.D.1
Raz, S.2
Sander, C.J.3
-
45
-
-
0035887450
-
The effects of catechol-O-methyltransferase inhibition on estrogen metabolite and oxidative DNA damage levels in estradiol-treated MCF-7 cells
-
Lavigne JA, Goodman JE, Fonong T, Odwin S, He P, Roberts DW, Yager JD (2001) The effects of catechol-O-methyltransferase inhibition on estrogen metabolite and oxidative DNA damage levels in estradiol-treated MCF-7 cells. Cancer Res 61:7488-94
-
(2001)
Cancer Res
, vol.61
, pp. 7488-7494
-
-
Lavigne, J.A.1
Goodman, J.E.2
Fonong, T.3
Odwin, S.4
He, P.5
Roberts, D.W.6
Yager, J.D.7
-
46
-
-
0037646999
-
17Beta-estradiol activates ICI 182,780-sensitive estrogen receptors and cyclic GMP-dependent thioredoxin expression for neuroprotection
-
Lee SY, Andoh T, Murphy DL, Chiueh CC (2003) 17beta-estradiol activates ICI 182,780-sensitive estrogen receptors and cyclic GMP-dependent thioredoxin expression for neuroprotection. FASEB J 17:947-8
-
(2003)
FASEB J
, vol.17
, pp. 947-948
-
-
Lee, S.Y.1
Andoh, T.2
Murphy, D.L.3
Chiueh, C.C.4
-
47
-
-
0028067014
-
Aromatization and hydrolysis of norethisterone-3-oxime in rabbit
-
Li QG (1994) Aromatization and hydrolysis of norethisterone-3-oxime in rabbit. J Steroid Biochem Mol Biol 49:227-31
-
(1994)
J Steroid Biochem Mol Biol
, vol.49
, pp. 227-231
-
-
Li, Q.G.1
-
48
-
-
0033614617
-
Expression of nitric oxide synthase (NOS)-2 following permanent focal ischemia and the role of nitric oxide in infarct generation in male, female and NOS-2 gene-deficient mice
-
Loihl AK, Asensio V, Campbell IL, Murphy S (1999) Expression of nitric oxide synthase (NOS)-2 following permanent focal ischemia and the role of nitric oxide in infarct generation in male, female and NOS-2 gene-deficient mice. Brain Res 830:155-64
-
(1999)
Brain Res
, vol.830
, pp. 155-164
-
-
Loihl, A.K.1
Asensio, V.2
Campbell, I.L.3
Murphy, S.4
-
49
-
-
0034329823
-
NMDA but not non-NMDA excitotoxicity is mediated by Poly(ADP-ribose) polymerase
-
Mandir AS, Poitras MF, Berliner AR, Herring WJ, Guastella DB, Feldman A, Poirier GG, Wang ZQ, Dawson TM, Dawson VL (2000) NMDA but not non-NMDA excitotoxicity is mediated by Poly(ADP-ribose) polymerase. J Neurosci 20:8005-11
-
(2000)
J Neurosci
, vol.20
, pp. 8005-8011
-
-
Mandir, A.S.1
Poitras, M.F.2
Berliner, A.R.3
Herring, W.J.4
Guastella, D.B.5
Feldman, A.6
Poirier, G.G.7
Wang, Z.Q.8
Dawson, T.M.9
Dawson, V.L.10
-
50
-
-
0034745252
-
Postischemic estrogen reduces hypoperfusion and secondary ischemia after experimental stroke
-
McCullough LD, Alkayed NJ, Traystman RJ, Williams MJ, Hurn PD (2001) Postischemic estrogen reduces hypoperfusion and secondary ischemia after experimental stroke. Stroke 32:796-802
-
(2001)
Stroke
, vol.32
, pp. 796-802
-
-
McCullough, L.D.1
Alkayed, N.J.2
Traystman, R.J.3
Williams, M.J.4
Hurn, P.D.5
-
51
-
-
0842322738
-
Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia
-
McCullough L, Wu L, Haughey N, Liang X, Hand T, Wang Q, Breyer RM, Andreasson K (2004) Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia. J Neurosci 24:257-68
-
(2004)
J Neurosci
, vol.24
, pp. 257-268
-
-
McCullough, L.1
Wu, L.2
Haughey, N.3
Liang, X.4
Hand, T.5
Wang, Q.6
Breyer, R.M.7
Andreasson, K.8
-
52
-
-
0141535178
-
Aromatase cytochrome P450 and extragonadal estrogen play a role in ischemic neuroprotection
-
McCullough LD, Blizzard K, Simpson ER, Oz OK, Hurn PD (2003) Aromatase cytochrome P450 and extragonadal estrogen play a role in ischemic neuroprotection. J Neurosci 23:8701-5
-
(2003)
J Neurosci
, vol.23
, pp. 8701-8705
-
-
McCullough, L.D.1
Blizzard, K.2
Simpson, E.R.3
Oz, O.K.4
Hurn, P.D.5
-
53
-
-
0038268485
-
Estrogen and ischemic neuroprotection: An integrated view
-
McCullough LD, Hurn PD (2003) Estrogen and ischemic neuroprotection: an integrated view. Trends Endocrinol Metab 14:228-35
-
(2003)
Trends Endocrinol Metab
, vol.14
, pp. 228-235
-
-
McCullough, L.D.1
Hurn, P.D.2
-
54
-
-
0034068520
-
Activation of poly(ADP-ribose) polymerase in the rat hippocampus may contribute to cellular recovery following sublethal transient global ischemia
-
Nagayama T, Simon RP, Chen D, Henshall DC, Pei W, Stetler RA, Chen J (2000) Activation of poly(ADP-ribose) polymerase in the rat hippocampus may contribute to cellular recovery following sublethal transient global ischemia. J Neurochem 74:1636-45
-
(2000)
J Neurochem
, vol.74
, pp. 1636-1645
-
-
Nagayama, T.1
Simon, R.P.2
Chen, D.3
Henshall, D.C.4
Pei, W.5
Stetler, R.A.6
Chen, J.7
-
55
-
-
0344813701
-
The selective inhibitor of neuronal nitric oxide synthase, 7-nitroindazole, reduces the delayed neuronal damage due to forebrain ischemia in rats
-
discussion 1253-1244
-
Nanri K, Montecot C, Springhetti V, Seylaz J, Pinard E (1998) The selective inhibitor of neuronal nitric oxide synthase, 7-nitroindazole, reduces the delayed neuronal damage due to forebrain ischemia in rats. Stroke 29:1248-53; discussion 1253-1244
-
(1998)
Stroke
, vol.29
, pp. 1248-1253
-
-
Nanri, K.1
Montecot, C.2
Springhetti, V.3
Seylaz, J.4
Pinard, E.5
-
56
-
-
0038582584
-
Role of superoxide in poly(ADP-ribose) polymerase upregulation after transient cerebral ischemia
-
Narasimhan P, Fujimura M, Noshita N, Chan PH (2003) Role of superoxide in poly(ADP-ribose) polymerase upregulation after transient cerebral ischemia. Brain Res Mol Brain Res 113:28-36
-
(2003)
Brain Res Mol Brain Res
, vol.113
, pp. 28-36
-
-
Narasimhan, P.1
Fujimura, M.2
Noshita, N.3
Chan, P.H.4
-
57
-
-
0035898755
-
Cell death in the development of the posterior cortex in male and female rats
-
Nunez JL, Lauschke DM, Juraska JM (2001) Cell death in the development of the posterior cortex in male and female rats. J Comp Neurol 436:32-41
-
(2001)
J Comp Neurol
, vol.436
, pp. 32-41
-
-
Nunez, J.L.1
Lauschke, D.M.2
Juraska, J.M.3
-
58
-
-
0032487513
-
Cerebral vasodilating capacity during forebrain ischemia: Effects of chronic estrogen depletion and repletion and the role of neuronal nitric oxide synthase
-
Pelligrino DA, Santizo R, Baughman VL, Wang Q (1998) Cerebral vasodilating capacity during forebrain ischemia: effects of chronic estrogen depletion and repletion and the role of neuronal nitric oxide synthase. Neuroreport 9:3285-91
-
(1998)
Neuroreport
, vol.9
, pp. 3285-3291
-
-
Pelligrino, D.A.1
Santizo, R.2
Baughman, V.L.3
Wang, Q.4
-
59
-
-
0032999788
-
Poly (ADP-ribose) polymerase, nitric oxide and cell death
-
Pieper AA, Verma A, Zhang J, Snyder SH (1999) Poly (ADP-ribose) polymerase, nitric oxide and cell death. Trends Pharmacol Sci 20:171-81
-
(1999)
Trends Pharmacol Sci
, vol.20
, pp. 171-181
-
-
Pieper, A.A.1
Verma, A.2
Zhang, J.3
Snyder, S.H.4
-
60
-
-
1842586119
-
Nuclear translocation of apoptosis-inducing factor after focal cerebral ischemia
-
Plesnila N, Zhu C, Culmsee C, Groger M, Moskowitz MA, Blomgren K (2004) Nuclear translocation of apoptosis-inducing factor after focal cerebral ischemia. J Cereb Blood Flow Metab 24:458-66
-
(2004)
J Cereb Blood Flow Metab
, vol.24
, pp. 458-466
-
-
Plesnila, N.1
Zhu, C.2
Culmsee, C.3
Groger, M.4
Moskowitz, M.A.5
Blomgren, K.6
-
61
-
-
0034128362
-
Gender differences in acute CNS trauma and stroke: Neuroprotective effects of estrogen and progesterone
-
Roof RL, Hall ED (2000) Gender differences in acute CNS trauma and stroke: neuroprotective effects of estrogen and progesterone. J Neurotrauma 17:367-88
-
(2000)
J Neurotrauma
, vol.17
, pp. 367-388
-
-
Roof, R.L.1
Hall, E.D.2
-
62
-
-
0030988138
-
Nitric oxide synthase in models of focal ischemia
-
Samdani AF, Dawson TM, Dawson VL (1997) Nitric oxide synthase in models of focal ischemia. Stroke 28:1283-8
-
(1997)
Stroke
, vol.28
, pp. 1283-1288
-
-
Samdani, A.F.1
Dawson, T.M.2
Dawson, V.L.3
-
63
-
-
0033755322
-
Stroke outcome in double-mutant antioxidant transgenic mice
-
Sampei K, Mandir AS, Asano Y, Wong PC, Traystman RJ, Dawson VL, Dawson TM, Hurn PD (2000) Stroke outcome in double-mutant antioxidant transgenic mice. Stroke 31:2685-91
-
(2000)
Stroke
, vol.31
, pp. 2685-2691
-
-
Sampei, K.1
Mandir, A.S.2
Asano, Y.3
Wong, P.C.4
Traystman, R.J.5
Dawson, V.L.6
Dawson, T.M.7
Hurn, P.D.8
-
64
-
-
0033981785
-
Estrogen receptor antagonist ICI182,780 exacerbates ischemic injury in female mouse
-
Sawada M, Alkayed NJ, Goto S, Crain BJ, Traystman RJ, Shaivitz A, Nelson RJ, Hurn PD (2000) Estrogen receptor antagonist ICI182,780 exacerbates ischemic injury in female mouse. J Cereb Blood Flow Metab 20:112-8
-
(2000)
J Cereb Blood Flow Metab
, vol.20
, pp. 112-118
-
-
Sawada, M.1
Alkayed, N.J.2
Goto, S.3
Crain, B.J.4
Traystman, R.J.5
Shaivitz, A.6
Nelson, R.J.7
Hurn, P.D.8
-
65
-
-
4544354817
-
Impact of gender on upregulation of antioxidant defence mechanisms in Alzheimer's disease brain
-
Schuessel K, Leutner S, Cairns NJ, Muller WE, Eckert A (2004) Impact of gender on upregulation of antioxidant defence mechanisms in Alzheimer's disease brain. Neural Transm 111:1167-82
-
(2004)
Neural Transm
, vol.111
, pp. 1167-1182
-
-
Schuessel, K.1
Leutner, S.2
Cairns, N.J.3
Muller, W.E.4
Eckert, A.5
-
66
-
-
0034724188
-
Castration increases and androgens decrease nitric oxide synthase activity in the brain: Physiologic implications
-
Singh R, Pervin S, Shryne J, Gorski R, Chaudhuri G (2000) Castration increases and androgens decrease nitric oxide synthase activity in the brain: physiologic implications. Proc Natl Acad Sci USA 97:3672-7
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3672-3677
-
-
Singh, R.1
Pervin, S.2
Shryne, J.3
Gorski, R.4
Chaudhuri, G.5
-
67
-
-
2542459293
-
17Beta-estradiol attenuates glutamate-induced apoptosis and preserves electrophysiologic function in primary cortical neurons
-
Sribnick EA, Ray SK, Nowak MW, Li L, Banik NL (2004) 17Beta-estradiol attenuates glutamate-induced apoptosis and preserves electrophysiologic function in primary cortical neurons. J Neurosci Res 76:688-96
-
(2004)
J Neurosci Res
, vol.76
, pp. 688-696
-
-
Sribnick, E.A.1
Ray, S.K.2
Nowak, M.W.3
Li, L.4
Banik, N.L.5
-
68
-
-
0035386291
-
Brain damage, sex hormones and recovery: A new role for progesterone and estrogen?
-
Stein DG (2001) Brain damage, sex hormones and recovery: a new role for progesterone and estrogen? Trends Neurosci 24:386-91
-
(2001)
Trends Neurosci
, vol.24
, pp. 386-391
-
-
Stein, D.G.1
-
69
-
-
0042266785
-
Modulation of antioxidant enzyme expression and function by estrogen
-
Strehlow K, Rotter S, Wassmann S, Adam O, Grohe C, Laufs K, Bohm M, Nickenig G (2003) Modulation of antioxidant enzyme expression and function by estrogen. Circ Res 93:170-7
-
(2003)
Circ Res
, vol.93
, pp. 170-177
-
-
Strehlow, K.1
Rotter, S.2
Wassmann, S.3
Adam, O.4
Grohe, C.5
Laufs, K.6
Bohm, M.7
Nickenig, G.8
-
70
-
-
0030893956
-
Comparable studies of the incidence of stroke and its pathological types: Results from an international collaboration
-
International Stroke Incidence Collaboration
-
Sudlow CL, Warlow CP (1997) Comparable studies of the incidence of stroke and its pathological types: results from an international collaboration. International Stroke Incidence Collaboration. Stroke 28:491-9
-
(1997)
Stroke
, vol.28
, pp. 491-499
-
-
Sudlow, C.L.1
Warlow, C.P.2
-
71
-
-
0032127666
-
Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion
-
Szabo C, Dawson VL (1998) Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion. Trends Pharmacol Sci 19:287-98
-
(1998)
Trends Pharmacol Sci
, vol.19
, pp. 287-298
-
-
Szabo, C.1
Dawson, V.L.2
-
72
-
-
0030889308
-
Stroke trends in the WHO MONICA project
-
Thorvaldsen P, Kuulasmaa K, Rajakangas AM, Rastenyte D, Sarti C, Wilhelmsen L (1997) Stroke trends in the WHO MONICA project. Stroke 28:500-6
-
(1997)
Stroke
, vol.28
, pp. 500-506
-
-
Thorvaldsen, P.1
Kuulasmaa, K.2
Rajakangas, A.M.3
Rastenyte, D.4
Sarti, C.5
Wilhelmsen, L.6
-
73
-
-
0035201329
-
Experimental stroke in the female diabetic, db/db, mouse
-
Vannucci SJ, Willing LB, Goto S, Alkayed NJ, Brucklacher RM, Wood TL, Towfighi J, Hurn PD, Simpson IA (2001) Experimental stroke in the female diabetic, db/db, mouse. J Cereb Blood Flow Metab 21:52-60
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 52-60
-
-
Vannucci, S.J.1
Willing, L.B.2
Goto, S.3
Alkayed, N.J.4
Brucklacher, R.M.5
Wood, T.L.6
Towfighi, J.7
Hurn, P.D.8
Simpson, I.A.9
-
74
-
-
0344643456
-
Peroxynitrite-induced cytotoxicity: Mechanism and opportunities for intervention
-
Virag L, Szabo E, Gergely P, Szabo C (2003) Peroxynitrite-induced cytotoxicity: mechanism and opportunities for intervention. Toxicol Lett 140-1:113-24
-
(2003)
Toxicol Lett
, vol.140-141
, pp. 113-124
-
-
Virag, L.1
Szabo, E.2
Gergely, P.3
Szabo, C.4
-
75
-
-
0036733355
-
The therapeutic potential of poly(ADP-ribose) polymerase inhibitors
-
Virag L, Szabo C (2002) The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol Rev 54:375-429
-
(2002)
Pharmacol Rev
, vol.54
, pp. 375-429
-
-
Virag, L.1
Szabo, C.2
-
76
-
-
10744224196
-
Prehospital cardiac arrest and the adverse effect of male gender, but not age, on outcome
-
Vukmir RB (2003) Prehospital cardiac arrest and the adverse effect of male gender, but not age, on outcome. J Womens Health (Larchmt) 12:667-73
-
(2003)
J Womens Health (Larchmt)
, vol.12
, pp. 667-673
-
-
Vukmir, R.B.1
-
77
-
-
2442534125
-
Estrogen attenuates nuclear factor-kappa B activation induced by transient cerebral ischemia
-
Wen Y, Yang S, Liu R, Perez E, Yi KD, Koulen P, Simpkins JW (2004) Estrogen attenuates nuclear factor-kappa B activation induced by transient cerebral ischemia. Brain Res 1008:147-54
-
(2004)
Brain Res
, vol.1008
, pp. 147-154
-
-
Wen, Y.1
Yang, S.2
Liu, R.3
Perez, E.4
Yi, K.D.5
Koulen, P.6
Simpkins, J.W.7
-
78
-
-
0035663680
-
Estradiol is a protective factor in the adult and aging brain: Understanding of mechanisms derived from in vivo and in vitro studies
-
Wise PM, Dubal DB, Wilson ME, Rau SW, Bottner M, Rosewell KL (2001) Estradiol is a protective factor in the adult and aging brain: understanding of mechanisms derived from in vivo and in vitro studies. Brain Res Brain Res Rev 37:313-9
-
(2001)
Brain Res Brain Res Rev
, vol.37
, pp. 313-319
-
-
Wise, P.M.1
Dubal, D.B.2
Wilson, M.E.3
Rau, S.W.4
Bottner, M.5
Rosewell, K.L.6
-
80
-
-
0348109491
-
Poly(ADP-ribose) polymerase-1 and apoptosis inducing factor in neurotoxicity
-
Yu SW, Wang H, Dawson TM, Dawson VL (2003) Poly(ADP-ribose) polymerase-1 and apoptosis inducing factor in neurotoxicity. Neurobiol Dis 14:303-17
-
(2003)
Neurobiol Dis
, vol.14
, pp. 303-317
-
-
Yu, S.W.1
Wang, H.2
Dawson, T.M.3
Dawson, V.L.4
-
81
-
-
0037067317
-
Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor
-
Yu SW, Wang H, Poitras MF, Coombs C, Bowers WJ, Federoff HJ, Poirier GG, Dawson TM, Dawson VL (2002) Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science 297:259-63
-
(2002)
Science
, vol.297
, pp. 259-263
-
-
Yu, S.W.1
Wang, H.2
Poitras, M.F.3
Coombs, C.4
Bowers, W.J.5
Federoff, H.J.6
Poirier, G.G.7
Dawson, T.M.8
Dawson, V.L.9
-
82
-
-
0037421502
-
Sex-related differences in neuronal cell survival and signaling in rats
-
Zhang L, Li PP, Feng X, Barker JL, Smith SV, Rubinow DR (2003) Sex-related differences in neuronal cell survival and signaling in rats. Neurosci Lett 337:65-8
-
(2003)
Neurosci Lett
, vol.337
, pp. 65-68
-
-
Zhang, L.1
Li, P.P.2
Feng, X.3
Barker, J.L.4
Smith, S.V.5
Rubinow, D.R.6
-
83
-
-
0032536475
-
Effects of gender and estradiol treatment on focal brain ischemia
-
Zhang YQ, Shi J, Rajakumar G, Day AL, Simpkins JW (1998) Effects of gender and estradiol treatment on focal brain ischemia. Brain Res 784:321-4
-
(1998)
Brain Res
, vol.784
, pp. 321-324
-
-
Zhang, Y.Q.1
Shi, J.2
Rajakumar, G.3
Day, A.L.4
Simpkins, J.W.5
|