Primary and secondary thyroid hormone transporters

Thyroid Research

Volumn 4, Issue SUPPL. 1, 2011, Pages

  Kinne, Anita ^a   Schülein, Ralf ^a   Krause, Gerd ^a  

^a LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 79961195158     PISSN: None     EISSN: 17566614     Source Type: Journal    
DOI: 10.1186/1756-6614-4-S1-S7     Document Type: Review

References (86)

1. Association between mutations in a thyroid hormone transporter and severe X-linked psychomotor retardation. EC Friesema A Grueters H Biebermann H Krude A von Moers M Reeser TG Barrett EE Mancilla J Svensson MH Kester,, et al. Lancet 2004 364 1435 1437 10.1016/S0140-6736(04)17226-7 15488219 (Pubitemid 39370719)
2. X-linked paroxysmal dyskinesia and severe global retardation caused by defective MCT8 gene. K Brockmann AM Dumitrescu TT Best F Hanefeld S Refetoff, J Neurol 2005 252 663 666 10.1007/s00415-005-0713-3 15834651 (Pubitemid 40864039)
3. A novel syndrome combining thyroid and neurological abnormalities is associated with mutations in a monocarboxylate transporter gene. AM Dumitrescu XH Liao TB Best K Brockmann S Refetoff, Am J Hum Genet 2004 74 168 175 10.1086/380999 14661163 (Pubitemid 38085248)
4. Allan-Herndon-Dudley syndrome and the monocarboxylate transporter 8 (MCT8) gene. CE Schwartz MM May NJ Carpenter RC Rogers J Martin MG Bialer J Ward J Sanabria S Marsa JA Lewis,, et al. Am J Hum Genet 2005 77 41 53 10.1086/431313 15889350 (Pubitemid 40848035)
5. Unexpected peripheral markers of thyroid function in a patient with a novel mutation of the MCT8 thyroid hormone transporter gene. V Herzovich E Vaiani R Marino G Dratler JM Lazzati S Tilitzky P Ramirez S Iorcansky MA Rivarola A Belgorosky, Horm Res 2007 67 1 6 16974106
6. Decreased cellular uptake and metabolism in Allan-Herndon-Dudley syndrome (AHDS) due to a novel mutation in the MCT8 thyroid hormone transporter. CM Maranduba EC Friesema F Kok MH Kester J Jansen AL Sertie MR Passos-Bueno TJ Visser, J Med Genet 2006 43 457 460 15980113
7. Timing of thyroid hormone action in the developing brain: Clinical observations and experimental findings. RT Zoeller J Rovet, Journal of Neuroendocrinology 2004 16 809 818 10.1111/j.1365-2826.2004.01243.x 15500540 (Pubitemid 39489993)
8. Thyroid hormone, brain development, and the environment. TR Zoeller AL Dowling CT Herzig EA Iannacone KJ Gauger R Bansal, Environ Health Perspect 2002 110 Suppl 3 355 361 12060829 (Pubitemid 34661941)
9. Iodine and brain development. J Bernal, Biofactors 1999 10 271 276 10.1002/biof.5520100227 10609893 (Pubitemid 29533840)
10. Neuronal 3',3,5-triiodothyronine (T3) uptake and behavioral phenotype of mice deficient in Mct8, the neuronal T3 transporter mutated in Allan-Herndon-Dudley syndrome. EK Wirth S Roth C Blechschmidt SM Holter L Becker I Racz A Zimmer T Klopstock V Gailus-Durner H Fuchs,, et al. J Neurosci 2009 29 9439 9449 10.1523/JNEUROSCI.6055-08.2009 19641107
11. Tissue-specific thyroid hormone deprivation and excess in monocarboxylate transporter (mct) 8-deficient mice. AM Dumitrescu XH Liao RE Weiss K Millen S Refetoff, Endocrinology 2006 147 4036 4043 10.1210/en.2006-0390 16709608 (Pubitemid 44268357)
12. Abnormal thyroid hormone metabolism in mice lacking the monocarboxylate transporter 8. M Trajkovic TJ Visser J Mittag S Horn J Lukas VM Darras G Raivich K Bauer H Heuer, J Clin Invest 2007 117 627 635 10.1172/JCI28253 17318265 (Pubitemid 46348521)
13. Expression of the thyroid hormone transporters monocarboxylate transporter-8 (SLC16A2) and organic ion transporter-14 (SLCO1C1) at the blood-brain barrier. LM Roberts K Woodford M Zhou DS Black JE Haggerty EH Tate KK Grindstaff W Mengesha C Raman N Zerangue, Endocrinology 2008 149 6251 6261 10.1210/en.2008-0378 18687783
14. Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter. EC Friesema S Ganguly A Abdalla JE Manning Fox AP Halestrap TJ Visser, J Biol Chem 2003 278 40128 40135 10.1074/jbc.M300909200 12871948 (Pubitemid 37248580)
15. The monocarboxylate transporter 8 linked to human psychomotor retardation is highly expressed in thyroid hormone-sensitive neuron populations. H Heuer MK Maier S Iden J Mittag EC Friesema TJ Visser K Bauer, Endocrinology 2005 146 1701 1706 10.1210/en.2004-1179 15661862 (Pubitemid 40396877)
16. Thyroid hormone transporters. EC Friesema J Jansen TJ Visser, Biochem Soc Trans 2005 33 228 232 10.1042/BST0330228 15667314 (Pubitemid 40313809)
17. The role of drug transporters at the blood-brain barrier. AG de Boer I van dS PJ Gaillard, Annu Rev Pharmacol Toxicol 2003 43 629 656 10.1146/annurev.pharmtox.43.100901.140204 12415123 (Pubitemid 37372656)
18. Glycoprotein-associated amino acid exchangers: broadening the range of transport specificity. F Verrey C Meier G Rossier LC Kuhn, Pflugers Arch 2000 440 503 512 10958334 (Pubitemid 30490328)
19. 4F2 (CD98) heavy chain is associated covalently with an amino acid transporter and controls intracellular trafficking and membrane topology of 4F2 heterodimer. E Nakamura M Sato H Yang F Miyagawa M Harasaki K Tomita S Matsuoka A Noma K Iwai N Minato, J Biol Chem 1999 274 3009 3016 10.1074/jbc.274.5.3009 9915839 (Pubitemid 29075388)
20. Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins. H Sato M Tamba T Ishii S Bannai, J Biol Chem 1999 274 11455 11458 10.1074/jbc.274.17.11455 10206947
21. Membrane topology of system xc- light subunit reveals a re-entrant loop with substrate-restricted accessibility. E Gasol M Jimenez-Vidal J Chillaron A Zorzano M Palacin, J Biol Chem 2004 279 31228 31236 10.1074/jbc.M402428200 15151999 (Pubitemid 39037788)
22. Human cystine/glutamate transporter: cDNA cloning and upregulation by oxidative stress in glioma cells. JY Kim Y Kanai A Chairoungdua SH Cha H Matsuo DK Kim J Inatomi H Sawa Y Ida H Endou, Biochim Biophys Acta 2001 1512 335 344 10.1016/S0005-2736(01)00338-8 11406111 (Pubitemid 32530781)
23. Molecular characterization and tissue distribution of a new organic anion transporter subtype (oatp3) that transports thyroid hormones and taurocholate and comparison with oatp2. T Abe M Kakyo H Sakagami T Tokui T Nishio M Tanemoto H Nomura SC Hebert S Matsuno H Kondo,, et al. J Biol Chem 1998 273 22395 22401 10.1074/jbc.273.35.22395 9712861 (Pubitemid 28399802)
24. Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli. Y Huang MJ Lemieux J Song M Auer DN Wang, Science 2003 301 616 620 10.1126/science.1087619 12893936 (Pubitemid 36927940)
25. The role of charged residues in the transmembrane helices of monocarboxylate transporter 1 and its ancillary protein basigin in determining plasma membrane expression and catalytic activity. C Manoharan MC Wilson RB Sessions AP Halestrap, Mol Membr Biol 2006 23 486 498 10.1080/09687860600841967 17127621 (Pubitemid 44837734)
26. Essential molecular determinants for thyroid hormone transport and first structural implications for monocarboxylate transporter 8. A Kinne G Kleinau CS Hoefig A Gruters J Kohrle G Krause U Schweizer, J Biol Chem 2010 285 28054 28063 10.1074/jbc.M110.129577 20628049
27. Evidence of Evolutionary Conservation of Function between the Thyroxine Transporter Oatp1c1 and Major Facilitator Superfamily Members. DE Westholm JD Marold KJ Viken AH Duerst GW Anderson JN Rumbley, Endocrinology 2010 151 12 5941 5951 10.1210/en.2010-0640 20881245
28. Structure and mechanism of the lactose permease of Escherichia coli. J Abramson I Smirnova V Kasho G Verner HR Kaback S Iwata, Science 2003 301 610 615 10.1126/science.1088196 12893935 (Pubitemid 36927939)
29. Structural determination of wild-type lactose permease. L Guan O Mirza G Verner S Iwata HR Kaback, Proc Natl Acad Sci U S A 2007 104 15294 15298 10.1073/pnas.0707688104 17881559 (Pubitemid 47502911)
30. Structure and mechanism of a Na+-independent amino acid transporter. PL Shaffer A Goehring A Shankaranarayanan E Gouaux, Science 2009 325 1010 1014 10.1126/science.1176088 19608859
31. Crystal structure of a bacterial homologue of Na+/Cl - dependent neurotransmitter transporters. A Yamashita SK Singh T Kawate Y Jin E Gouaux, Nature 2005 437 215 223 10.1038/nature03978 16041361 (Pubitemid 41294479)
32. Transport of thyroid hormones is selectively inhibited by 3-iodothyronamine. AG Ianculescu EC Friesema TJ Visser KM Giacomini TS Scanlan, Mol Biosyst 2010 6 1403 1410 10.1039/b926588k 20358049
33. Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters. DK Kim Y Kanai A Chairoungdua H Matsuo SH Cha H Endou, J Biol Chem 2001 276 17221 17228 10.1074/jbc.M009462200 11278508
34. Effective cellular uptake and efflux of thyroid hormone by human monocarboxylate transporter 10. EC Friesema J Jansen JW Jachtenberg WE Visser MH Kester TJ Visser, Mol Endocrinol 2008 22 1357 1369 10.1210/me.2007-0112 18337592 (Pubitemid 351786996)
35. Impact of OATP transporters on pharmacokinetics. A Kalliokoski M Niemi, Br J Pharmacol 2009 158 693 705 10.1111/j.1476-5381.2009.00430.x 19785645
36. Pharmacogenomics of human OATP transporters. J König A Seithel U Gradhand MF Fromm, Naunyn Schmiedebergs Arch Pharmacol 2006 372 432 443 10.1007/s00210-006-0040-y 16525793
37. Involvement of multispecific organic anion transporter, Oatp14 (Slc21a14), in the transport of thyroxine across the blood-brain barrier. K Tohyama H Kusuhara Y Sugiyama, Endocrinology 2004 145 4384 4391 10.1210/en.2004-0058 15166123 (Pubitemid 39120588)
38. Functional characterization of rat brain-specific organic anion transporter (Oatp14) at the blood-brain barrier: high affinity transporter for thyroxine. D Sugiyama H Kusuhara H Taniguchi S Ishikawa Y Nozaki H Aburatani Y Sugiyama, J Biol Chem 2003 278 43489 43495 10.1074/jbc.M306933200 12923172 (Pubitemid 37345972)
39. Identification of a novel human organic anion transporting polypeptide as a high affinity thyroxine transporter. F Pizzagalli B Hagenbuch B Stieger U Klenk G Folkers PJ Meier, Mol Endocrinol 2002 16 2283 2296 10.1210/me.2001-0309 12351693 (Pubitemid 35155540)
40. Thyroid hormone transport in and out of cells. WE Visser EC Friesema J Jansen TJ Visser, Trends Endocrinol Metab 2008 19 50 56 10.1016/j.tem.2007.11. 003 18291666 (Pubitemid 351317898)
41. Function and structure of heterodimeric amino acid transporters. CA Wagner F Lang S Broer, Am J Physiol Cell Physiol 2001 281 1077 C1093 11546643
42. Identification and functional characterization of a Na+-independent neutral amino acid transporter with broad substrate selectivity. H Segawa Y Fukasawa K Miyamoto E Takeda H Endou Y Kanai, J Biol Chem 1999 274 19745 19751 10.1074/jbc.274.28.19745 10391916
43. Thyroid hormone transport by the heterodimeric human system L amino acid transporter. EC Friesema R Docter EP Moerings F Verrey EP Krenning G Hennemann TJ Visser, Endocrinology 2001 142 4339 4348 10.1210/en.142.10.4339 11564694 (Pubitemid 32907062)
44. Transport interaction of L-cystine and L-glutamate in human diploid fibroblasts in culture. S Bannai E Kitamura, J Biol Chem 1980 255 2372 2376 7358676 (Pubitemid 10036038)
45. Role of proton dissociation in the transport of cystine and glutamate in human diploid fibroblasts in culture. S Bannai E Kitamura, J Biol Chem 1981 256 5770 5772 6113240 (Pubitemid 11043456)
46. Exchange of cystine and glutamate across plasma membrane of human fibroblasts. S Bannai, J Biol Chem 1986 261 2256 2263 2868011 (Pubitemid 17205155)
47. Minireview: Pathophysiological importance of thyroid hormone transporters. H Heuer TJ Visser, Endocrinology 2009 150 1078 1083 19179441
48. Pharmacokinetic role of L-type amino acid transporters LAT1 and LAT2. EM del Amo A Urtti M Yliperttula, Eur J Pharm Sci 2008 35 161 174 10.1016/j.ejps.2008.06.015 18656534
49. Functional heterodimeric amino acid transporters lacking cysteine residues involved in disulfide bond. R Pfeiffer B Spindler J Loffing PJ Skelly CB Shoemaker F Verrey, FEBS Lett 1998 439 157 162 10.1016/S0014-5793(98)01359-3 9849898 (Pubitemid 28537884)
50. The genetics of heteromeric amino acid transporters. M Palacin V Nunes M Font-Llitjos M Jimenez-Vidal J Fort E Gasol M Pineda L Feliubadalo J Chillaron A Zorzano, Physiology (Bethesda) 2005 20 112 124 15772300 (Pubitemid 40627552)
51. Pharmacogenomics of human OATP transporters. J Konig A Seithel U Gradhand MF Fromm, Naunyn Schmiedebergs Arch Pharmacol 2006 372 432 443 10.1007/s00210-006-0040-y 16525793
52. The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. AP Halestrap D Meredith, Pflugers Arch 2004 447 619 628 10.1007/s00424-003-1067-2 12739169 (Pubitemid 38241446)
53. CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression. P Kirk MC Wilson C Heddle MH Brown AN Barclay AP Halestrap, EMBO J 2000 19 3896 3904 10.1093/emboj/19.15.3896 10921872 (Pubitemid 30608530)
54. Characterization of antigen recognized by the monoclonal antibody (4F2): different molecular forms on human T and B lymphoblastoid cell lines. ME Hemler JL Strominger, J Immunol 1982 129 623 628 6177771 (Pubitemid 12039387)
55. Heteromeric amino acid transporters: biochemistry, genetics, and physiology. J Chillaron R Roca A Valencia A Zorzano M Palacin, Am J Physiol Renal Physiol 2001 281 995 1018 11704550
56. Site-directed mutagenesis of cysteine residues of large neutral amino acid transporter LAT1. RJ Boado JY Li C Chu F Ogoshi P Wise WM Pardridge, Biochim Biophys Acta 2005 1715 104 110 10.1016/j.bbamem.2005.07.007 16125134 (Pubitemid 41219698)
57. Identification and characterisation of human xCT that co-expresses, with 4F2 heavy chain, the amino acid transport activity system xc-. MT Bassi E Gasol M Manzoni M Pineda M Riboni R Martin A Zorzano G Borsani M Palacin, Pflugers Arch 2001 442 286 296 10.1007/s004240100537 11417227 (Pubitemid 32476650)
58. Interaction of methotrexate with organic-anion transporting polypeptide 1A2 and its genetic variants. I Badagnani RA Castro TR Taylor CM Brett CC Huang D Stryke M Kawamoto SJ Johns TE Ferrin EJ Carlson,, et al. J Pharmacol Exp Ther 2006 318 521 529 10.1124/jpet.106.104364 16702441 (Pubitemid 44061225)
59. Molecular aspects of thyroid hormone transporters, including MCT8, MCT10, and OATPs, and the effects of genetic variation in these transporters. WM van der Deure RP Peeters TJ Visser, J Mol Endocrinol 2010 44 1 11 10.1677/JME-09-0042 19541799
60. Site-directed mutagenesis of rabbit LAT1 at amino acids 219 and 234. RJ Boado JY Li WM Pardridge, J Neurochem 2003 84 1322 1331 10.1046/j.1471-4159. 2003.01622.x 12614332 (Pubitemid 36343598)
61. Association of 4F2hc with light chains LAT1, LAT2 or y+LAT2 requires different domains. A Broer B Friedrich CA Wagner S Fillon V Ganapathy F Lang S Broer, Biochem J 2001 355 725 731 11311135 (Pubitemid 32434090)
62. Thiol modification of cysteine 327 in the eighth transmembrane domain of the light subunit xCT of the heteromeric cystine/glutamate antiporter suggests close proximity to the substrate binding site/permeation pathway. M Jimenez-Vidal E Gasol A Zorzano V Nunes M Palacin J Chillaron, J Biol Chem 2004 279 11214 11221 10.1074/jbc.M309866200 14722095 (Pubitemid 38401616)
63. Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): implications for altered drug disposition and central nervous system drug entry. W Lee H Glaeser LH Smith RL Roberts GW Moeckel G Gervasini BF Leake RB Kim, J Biol Chem 2005 280 9610 9617 15632119 (Pubitemid 40409657)
64. Distribution of monocarboxylate transporters MCT1-MCT8 in rat tissues and human skeletal muscle. A Bonen M Heynen H Hatta, Appl Physiol Nutr Metab 2006 31 31 39 10.1139/h05-002 16604139 (Pubitemid 43863814)
65. Monocarboxylate transporter 8 expression in the human placenta: the effects of severe intrauterine growth restriction. SY Chan JA Franklyn HN Pemberton JN Bulmer TJ Visser CJ McCabe MD Kilby, J Endocrinol 2006 189 465 471 10.1677/joe.1.06582 16731778
66. Mice deficient in MCT8 reveal a mechanism regulating thyroid hormone secretion. C Di Cosmo XH Liao AM Dumitrescu NJ Philp RE Weiss S Refetoff, J Clin Invest 2010 120 3377 3388 10.1172/JCI42113 20679730
67. The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. AP Halestrap D Meredith, Pflugers Arch 2004 447 619 628 10.1007/s00424-003-1067-2 12739169 (Pubitemid 38241446)
68. Tissue-specific mRNA expression profiles of human solute carrier transporter superfamilies. M Nishimura S Naito, Drug Metab Pharmacokinet 2008 23 22 44 10.2133/dmpk.23.22 18305372
69. Expression and membrane localization of MCT isoforms along the length of the human intestine. RK Gill S Saksena WA Alrefai Z Sarwar JL Goldstein RE Carroll K Ramaswamy PK Dudeja, Am J Physiol Cell Physiol 2005 289 846 C852 10.1152/ajpcell.00112.2005 15901598
70. Identification of thyroid hormone transporters. EC Friesema R Docter EP Moerings B Stieger B Hagenbuch PJ Meier EP Krenning G Hennemann TJ Visser, Biochem Biophys Res Commun 1999 254 497 501 10.1006/bbrc.1998.9974 9918867 (Pubitemid 29290429)
71. Intestinal drug transporter expression and the impact of grapefruit juice in humans. H Glaeser DG Bailey GK Dresser JC Gregor UI Schwarz JS McGrath E Jolicoeur W Lee BF Leake RG Tirona,, et al. Clin Pharmacol Ther 2007 81 362 370 10.1038/sj.clpt.6100056 17215845 (Pubitemid 46364477)
72. Identification of thyroid hormone transporters in humans: different molecules are involved in a tissue-specific manner. K Fujiwara H Adachi T Nishio M Unno T Tokui M Okabe T Onogawa T Suzuki N Asano M Tanemoto,, et al. Endocrinology 2001 142 2005 2012 10.1210/en.142.5.2005 11316767 (Pubitemid 32405959)
73. Tissue distribution and ontogeny of mouse organic anion transporting polypeptides (Oatps). X Cheng J Maher C Chen CD Klaassen, Drug Metab Dispos 2005 33 1062 1073 10.1124/dmd.105.003640 15843488 (Pubitemid 41002790)
74. LAT2, a new basolateral 4F2hc/CD98-associated amino acid transporter of kidney and intestine. G Rossier C Meier C Bauch V Summa B Sordat F Verrey LC Kuhn, J Biol Chem 1999 274 34948 34954 10.1074/jbc.274.49.34948 10574970 (Pubitemid 129509543)
75. mRNA expression and amino acid transport characteristics of cultured human brain microvascular endothelial cells (hBME). N Umeki Y Fukasawa S Ohtsuki S Hori Y Watanabe Y Kohno T Terasaki, Drug Metab Pharmacokinet 2002 17 367 373 10.2133/dmpk.17.367 15618688
76. Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98). Y Kanai H Segawa K Miyamoto H Uchino E Takeda H Endou, J Biol Chem 1998 273 23629 23632 10.1074/jbc.273.37.23629 9726963 (Pubitemid 28435687)
77. Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines. O Yanagida Y Kanai A Chairoungdua DK Kim H Segawa T Nii SH Cha H Matsuo J Fukushima Y Fukasawa,, et al. Biochim Biophys Acta 2001 1514 291 302 10.1016/S0005-2736(01)00384-4 11557028 (Pubitemid 32831016)
78. Expression of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (4F2hc) in liver tumor lesions of rat models. H Ohkame H Masuda Y Ishii Y Kanai, J Surg Oncol 2001 78 265 271 10.1002/jso.1165 11745822 (Pubitemid 33097058)
79. Over-expression of renal LAT1 and LAT2 and enhanced L-DOPA uptake in SHR immortalized renal proximal tubular cells. MJ Pinho MP Serrao P Gomes U Hopfer PA Jose P Soares-da-Silva, Kidney Int 2004 66 216 226 10.1111/j.1523-1755.2004. 00722.x 15200428 (Pubitemid 38870097)
80. Localization of the System L Amino Acid Transporters LAT1 and LAT2 in Rat Gastrointestinal Tract. Y Kobayashi, Journal of the Kyorin Medical Society 2007 38 75 84
81. Developmental and cell type-specific expression of thyroid hormone transporters in the mouse brain and in primary brain cells. D Braun A Kinne AU Brauer R Sapin MO Klein J Kohrle EK Wirth U Schweizer, Glia 2011 59 463 471 10.1002/glia.21116 21264952
82. SLC7A8, a gene mapping within the lysinuric protein intolerance critical region, encodes a new member of the glycoprotein-associated amino acid transporter family. MT Bassi MP Sperandeo B Incerti A Bulfone A Pepe EM Surace C Gattuso A De Grandi A Buoninconti M Riboni,, et al. Genomics 1999 62 297 303 10.1006/geno.1999.5978 10610726 (Pubitemid 30053948)
83. Identification of a membrane protein, LAT-2, that Co-expresses with 4F2 heavy chain, an L-type amino acid transport activity with broad specificity for small and large zwitterionic amino acids. M Pineda E Fernandez D Torrents R Estevez C Lopez M Camps J Lloberas A Zorzano M Palacin, J Biol Chem 1999 274 19738 19744 10.1074/jbc.274.28.19738 10391915
84. Molecular cloning and expression of human xCT, the light chain of amino acid transport system xc-. H Sato M Tamba K Kuriyama-Matsumura S Okuno S Bannai, Antioxid Redox Signal 2000 2 665 671 10.1089/ars.2000.2.4-665 11213471 (Pubitemid 32062317)
85. Distribution of the cystine/glutamate antiporter system xc- in the brain, kidney, and duodenum. J Burdo R Dargusch D Schubert, J Histochem Cytochem 2006 54 549 557 10.1369/jhc.5A6840.2006 16399997
86. Thyroid hormone transport by the human monocarboxylate transporter 8 and its rate-limiting role in intracellular metabolism. EC Friesema GG Kuiper J Jansen TJ Visser MH Kester, Mol Endocrinol 2006 20 2761 2772 10.1210/me.2005-0256 16887882 (Pubitemid 44833533)