Membrane topology of System xc- light subunit reveals a re-entrant loop with substrate-restricted accessibility

Journal of Biological Chemistry

Volumn 279, Issue 30, 2004, Pages 31228-31236

  Gasol, Emma ^a   Jiménez Vidal, Maite ^a,b   Chillarón, Josep ^a   Zorzano, Antonio ^a   Palacín, Manuel ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b Institut de Recerca Oncologica   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; AMINO ACIDS; FLUORESCENCE; IMMUNOLOGY; ION EXCHANGE;

HETEROMERIC AMINO ACID TRANSPORTERS; MEMBRANE TOPOLOGY; SUBSTRATE BINDING; TRANSMEMBRANE DOMAINS;

CELL MEMBRANES;

(2 SULFONATOETHYL)METHANETHIOSULFATE; 3 (N MALEIMIDYLPROPIONYL)BIOCYTIN; 4 CARBOXYPHENYLGLYCINE; AMINO ACID; AMINO ACID TRANSPORTER; BIOCYTIN; CYSTEINE; GLUTAMIC ACID; HISTIDINE; THIOL DERIVATIVE; THIOMESYLIC ACID METHYL ESTER; THREONINE; UNCLASSIFIED DRUG;

ALPHA CHAIN; AMINO TERMINAL SEQUENCE; ARTICLE; BIOTINYLATION; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DISULFIDE BOND; ENZYME KINETICS; ENZYME SUBSTRATE COMPLEX; HUMAN; HUMAN CELL; IC 50; IMMUNOFLUORESCENCE; MEMBRANE STRUCTURE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; SYSTEM XC LIGHT SUBUNIT; TRANSMEMBRANE DOMAIN;

AMINO ACID TRANSPORT SYSTEM Y+; AMINO ACID TRANSPORT SYSTEMS; BINDING SITES; BIOTIN; CELL MEMBRANE; CYSTEINE; HELA CELLS; HUMANS; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN SUBUNITS; RECOMBINANT PROTEINS;

EID: 3843065666     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M402428200     Document Type: Article

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