The role of charged residues in the transmembrane helices of monocarboxylate transporter 1 and its ancillary protein basigin in determining plasma membrane expression and catalytic activity

Molecular Membrane Biology

Volumn 23, Issue 6, 2006, Pages 486-498

  Manoharan, Christine ^a   Wilson, Marieangela C ^a   Sessions, Richard B ^a   Halestrap, Andrew P ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Basigin; CD147; Fluorescence resonance energy transfer; Lactate transport; MCT1; Monocarboxylate transport; Protein protein interaction; Site directed mutagenesis; Xenopus oocytes

Indexed keywords

AMINO ACID; ARGININE; ASPARTIC ACID; CARRIER PROTEIN; CD147 ANTIGEN; EMBIGIN; GLUTAMIC ACID; GLUTAMINE; GLYCEROL 3 PHOSPHATE TRANSPORTER; MEMBRANE PROTEIN; MONOCARBOXYLATE TRANSPORTER 1; MONOCARBOXYLATE TRANSPORTER 2; MONOCARBOXYLATE TRANSPORTER 3; MONOCARBOXYLATE TRANSPORTER 4; MUTANT PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ALPHA HELIX; ANIMAL CELL; ARTICLE; CATALYSIS; CELL MEMBRANE; CELL STRAIN COS1; CONTROLLED STUDY; FEMALE; FUNCTIONAL PROTEOMICS; HUMAN; HUMAN CELL; HYDROGEN BOND; MOLECULAR MODEL; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; STRUCTURAL PROTEOMICS; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD147; ARGININE; BIOLOGICAL TRANSPORT; CATALYSIS; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; COS CELLS; GLUTAMIC ACID; HUMANS; MOLECULAR SEQUENCE DATA; MONOCARBOXYLIC ACID TRANSPORTERS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RATS; SEQUENCE HOMOLOGY, AMINO ACID; SYMPORTERS;

EID: 33751531456     PISSN: 09687688     EISSN: 14645203     Source Type: Journal    
DOI: 10.1080/09687860600841967     Document Type: Article

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