메뉴 건너뛰기




Volumn 117, Issue 3, 2007, Pages 627-635

Abnormal thyroid hormone metabolism in mice lacking the monocarboxylate transporter 8

Author keywords

[No Author keywords available]

Indexed keywords

DEIODINASE 1; DEIODINASE 2; DEIODINASE 3; IODOTHYRONINE; LIOTHYRONINE; MESSENGER RNA; MICROSOME ENZYME; MONOCARBOXYLATE TRANSPORTER 8; NEUROGRANIN; PROTIRELIN; THYROID HORMONE; THYROXINE; UNCLASSIFIED DRUG;

EID: 33847400151     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI28253     Document Type: Article
Times cited : (296)

References (41)
  • 1
    • 0027446957 scopus 로고
    • The role of thyroid hormones in prenatal and neonatal neurological development - current perspectives
    • Porterfield, S.P., and Hendrich, C.E. 1993. The role of thyroid hormones in prenatal and neonatal neurological development - current perspectives. Endocr. Rev. 14:94-106.
    • (1993) Endocr. Rev , vol.14 , pp. 94-106
    • Porterfield, S.P.1    Hendrich, C.E.2
  • 2
    • 0030836744 scopus 로고    scopus 로고
    • Molecular basis of thyroid hormone-dependent brain development
    • Oppenheimer, J.H., and Schwartz, H.L. 1997. Molecular basis of thyroid hormone-dependent brain development. Endocr. Rev. 18:462-475.
    • (1997) Endocr. Rev , vol.18 , pp. 462-475
    • Oppenheimer, J.H.1    Schwartz, H.L.2
  • 5
    • 27744592731 scopus 로고    scopus 로고
    • Thyroid hormones and brain development
    • Bernal, J. 2005. Thyroid hormones and brain development. Vitam. Horm. 71:95-122.
    • (2005) Vitam. Horm , vol.71 , pp. 95-122
    • Bernal, J.1
  • 6
    • 0034964207 scopus 로고    scopus 로고
    • Physiological and molecular basis of thyroid hormone action
    • Yen, P.M. 2001. Physiological and molecular basis of thyroid hormone action. Physiol. Rev. 81:1097-1142.
    • (2001) Physiol. Rev , vol.81 , pp. 1097-1142
    • Yen, P.M.1
  • 7
    • 0036191639 scopus 로고    scopus 로고
    • Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases
    • Bianco, A.C., Salvatore, D., Gereben, B., Berry, M.J., and Larsen, P.R. 2002. Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. Endocr. Rev. 23:38-89.
    • (2002) Endocr. Rev , vol.23 , pp. 38-89
    • Bianco, A.C.1    Salvatore, D.2    Gereben, B.3    Berry, M.J.4    Larsen, P.R.5
  • 8
    • 0036125773 scopus 로고    scopus 로고
    • Iodothyronine deiodinases
    • Kohrle, J. 2002. Iodothyronine deiodinases. Methods Enzymol. 347:125-167.
    • (2002) Methods Enzymol , vol.347 , pp. 125-167
    • Kohrle, J.1
  • 9
    • 0034892914 scopus 로고    scopus 로고
    • Plasma membrane transport of thyroid hormones and its role in thyroid hormone metabolism and bioavailability
    • Hennemann, G., et al. 2001. Plasma membrane transport of thyroid hormones and its role in thyroid hormone metabolism and bioavailability. Endocr. Rev. 22:451-476.
    • (2001) Endocr. Rev , vol.22 , pp. 451-476
    • Hennemann, G.1
  • 10
    • 0141891099 scopus 로고    scopus 로고
    • Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter
    • Friesema, E.C., et al. 2003. Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter. J. Biol. Chem. 278:40128-40135.
    • (2003) J. Biol. Chem , vol.278 , pp. 40128-40135
    • Friesema, E.C.1
  • 11
    • 5644276275 scopus 로고    scopus 로고
    • Association between mutations in a thyroid hormone transporter and severe X-linked psychomotor retardation
    • Friesema, E.C., et al. 2004. Association between mutations in a thyroid hormone transporter and severe X-linked psychomotor retardation. Lancet. 364:1435-1437.
    • (2004) Lancet , vol.364 , pp. 1435-1437
    • Friesema, E.C.1
  • 12
    • 0347634343 scopus 로고    scopus 로고
    • A novel syndrome combining thyroid and neurological abnormalities is associated with mutations in a monocarboxylate transporter gene
    • Dumitrescu, A.M., Liao, X.H., Best, T.B., Brockmann, K., and Refetoff, S. 2004. A novel syndrome combining thyroid and neurological abnormalities is associated with mutations in a monocarboxylate transporter gene. Am. J. Hum. Genet. 74:168-175.
    • (2004) Am. J. Hum. Genet , vol.74 , pp. 168-175
    • Dumitrescu, A.M.1    Liao, X.H.2    Best, T.B.3    Brockmann, K.4    Refetoff, S.5
  • 13
    • 20544454120 scopus 로고    scopus 로고
    • Allan-Herndon-Dudley syndrome and the monocarboxylate transporter 8 (MCT8) gene
    • Schwartz, C.E., et al. 2005. Allan-Herndon-Dudley syndrome and the monocarboxylate transporter 8 (MCT8) gene. Am. J. Hum. Genet. 77:41-53.
    • (2005) Am. J. Hum. Genet , vol.77 , pp. 41-53
    • Schwartz, C.E.1
  • 14
    • 15444378008 scopus 로고    scopus 로고
    • The monocarboxylate transporter 8 linked to human psychomotor retardation is highly expressed in thyroid hormone-sensitive neuron populations
    • Heuer, H., et al. 2005. The monocarboxylate transporter 8 linked to human psychomotor retardation is highly expressed in thyroid hormone-sensitive neuron populations. Endocrinology. 146:1701-1706.
    • (2005) Endocrinology , vol.146 , pp. 1701-1706
    • Heuer, H.1
  • 15
    • 20844451900 scopus 로고    scopus 로고
    • X-linked paroxysmal dyskinesia and severe global retardation caused by defective MCT8 gene
    • Brockmann, K., Dumitrescu, A.M., Best, T.T., Hanefeld, F., and Refetoff, S. 2005. X-linked paroxysmal dyskinesia and severe global retardation caused by defective MCT8 gene. J. Neurol. 252:663-666.
    • (2005) J. Neurol , vol.252 , pp. 663-666
    • Brockmann, K.1    Dumitrescu, A.M.2    Best, T.T.3    Hanefeld, F.4    Refetoff, S.5
  • 16
    • 0031945504 scopus 로고    scopus 로고
    • Rat mitochondrial glycerol-3-phosphate dehydrogenase gene: Multiple promoters, high levels in brown adipose tissue, and tissue-specific regulation by thyroid hormone
    • Gong, D.W., Bi, S., Weintraub, B.D., and Reitman, M. 1998. Rat mitochondrial glycerol-3-phosphate dehydrogenase gene: multiple promoters, high levels in brown adipose tissue, and tissue-specific regulation by thyroid hormone. DNA Cell Biol. 17:301-309.
    • (1998) DNA Cell Biol , vol.17 , pp. 301-309
    • Gong, D.W.1    Bi, S.2    Weintraub, B.D.3    Reitman, M.4
  • 17
    • 0031777309 scopus 로고    scopus 로고
    • Follicular cells of the thyroid gland require Pax8 gene function
    • Mansouri, A., Chowdhury, K., and Gruss, P. 1998. Follicular cells of the thyroid gland require Pax8 gene function. Nat. Genet. 19:87-90.
    • (1998) Nat. Genet , vol.19 , pp. 87-90
    • Mansouri, A.1    Chowdhury, K.2    Gruss, P.3
  • 19
    • 0030028213 scopus 로고    scopus 로고
    • Cell-specific effects of thyroid hormone on RC3/neurogranin expression in rat brain
    • Iniguez, M.A., et al. 1996. Cell-specific effects of thyroid hormone on RC3/neurogranin expression in rat brain. Endocrinology. 137:1032-1041.
    • (1996) Endocrinology , vol.137 , pp. 1032-1041
    • Iniguez, M.A.1
  • 20
    • 0037379663 scopus 로고    scopus 로고
    • Modelling brain diseases in mice: The challenges of design and analysis
    • Watase, K., and Zoghbi, H.Y. 2003. Modelling brain diseases in mice: the challenges of design and analysis. Nat. Rev. Genet. 4:296-307.
    • (2003) Nat. Rev. Genet , vol.4 , pp. 296-307
    • Watase, K.1    Zoghbi, H.Y.2
  • 22
    • 15444342300 scopus 로고    scopus 로고
    • Molecular characterization and tissue distribution of a new organic anion transporter subtype (oatp3) that transports thyroid hormones and taurocholate and comparison with oatp2
    • Abe, T., et al. 1998. Molecular characterization and tissue distribution of a new organic anion transporter subtype (oatp3) that transports thyroid hormones and taurocholate and comparison with oatp2. J. Biol. Chem. 273:22395-22401.
    • (1998) J. Biol. Chem , vol.273 , pp. 22395-22401
    • Abe, T.1
  • 24
    • 25144487661 scopus 로고    scopus 로고
    • Thyroid hormone transporters in health and disease
    • Jansen, J., Friesema, E.C., Milici, C., and Visser, T.J. 2005. Thyroid hormone transporters in health and disease. Thyroid. 15:757-768.
    • (2005) Thyroid , vol.15 , pp. 757-768
    • Jansen, J.1    Friesema, E.C.2    Milici, C.3    Visser, T.J.4
  • 25
    • 33845237318 scopus 로고    scopus 로고
    • Unexpected peripheral markers of thyroid function in a patient with a novel mutation of the MCT8 thyroid hormone transporter gene
    • Herzovich, V., et al. 2006. Unexpected peripheral markers of thyroid function in a patient with a novel mutation of the MCT8 thyroid hormone transporter gene. Horm. Res. 67:1-6.
    • (2006) Horm. Res , vol.67 , pp. 1-6
    • Herzovich, V.1
  • 26
    • 0024449620 scopus 로고
    • Thyroxine, triiodothyronine, and reverse triiodothyronine processing in the cerebellum: Autoradiographic studies in adult rats
    • Dratman, M.B., and Crutchfield, F.L. 1989. Thyroxine, triiodothyronine, and reverse triiodothyronine processing in the cerebellum: autoradiographic studies in adult rats. Endocrinology. 125:1723-1733.
    • (1989) Endocrinology , vol.125 , pp. 1723-1733
    • Dratman, M.B.1    Crutchfield, F.L.2
  • 27
    • 0025885336 scopus 로고
    • Transport of iodothyronines from bloodstream to brain: Contributions by blood: brain and choroid plexus:cerebrospinal fluid barriers
    • Dratman, M.B., Crutchfield, F.L., and Schoenhoff, M.B. 1991. Transport of iodothyronines from bloodstream to brain: contributions by blood: brain and choroid plexus:cerebrospinal fluid barriers. Brain Res. 554:229-236.
    • (1991) Brain Res , vol.554 , pp. 229-236
    • Dratman, M.B.1    Crutchfield, F.L.2    Schoenhoff, M.B.3
  • 28
    • 0028142636 scopus 로고
    • Film autoradiography identifies unique features of [125I]3,3′5′-(reverse) triiodothyronine transport from blood to brain
    • Cheng, L.Y., et al. 1994. Film autoradiography identifies unique features of [125I]3,3′5′-(reverse) triiodothyronine transport from blood to brain. J. Neurophysiol. 72:380-391.
    • (1994) J. Neurophysiol , vol.72 , pp. 380-391
    • Cheng, L.Y.1
  • 30
    • 0242384851 scopus 로고    scopus 로고
    • Functional characterization of rat brain-specific organic anion transporter (Oatp14) at the blood-brain barrier: High affinity transporter for thyroxine
    • Sugiyama, D., et al. 2003. Functional characterization of rat brain-specific organic anion transporter (Oatp14) at the blood-brain barrier: high affinity transporter for thyroxine. J. Biol. Chem. 278:43489-43495.
    • (2003) J. Biol. Chem , vol.278 , pp. 43489-43495
    • Sugiyama, D.1
  • 31
    • 33645217485 scopus 로고    scopus 로고
    • Novel neuroanatomical pathways for thyroid hormone action in the human anterior pituitary
    • Alkemade, A., et al. 2006. Novel neuroanatomical pathways for thyroid hormone action in the human anterior pituitary. Eur. J. Endocrinol. 154:491-500.
    • (2006) Eur. J. Endocrinol , vol.154 , pp. 491-500
    • Alkemade, A.1
  • 32
    • 26244446806 scopus 로고    scopus 로고
    • Extended clinical phenotype, endocrine investigations and functional studies of a loss-of-function mutation A150V in the thyroid hormone specific transporter MCT8
    • Biebermann, H., et al. 2005. Extended clinical phenotype, endocrine investigations and functional studies of a loss-of-function mutation A150V in the thyroid hormone specific transporter MCT8. Eur. J. Endocrinol. 153:359-366.
    • (2005) Eur. J. Endocrinol , vol.153 , pp. 359-366
    • Biebermann, H.1
  • 33
    • 0036138767 scopus 로고    scopus 로고
    • Congenital hypothyroid Pax8(-/-) mutant mice can be rescued by inactivating the TRalpha gene
    • Flamant, F., et al. 2002. Congenital hypothyroid Pax8(-/-) mutant mice can be rescued by inactivating the TRalpha gene. Mol. Endocrinol. 16:24-32.
    • (2002) Mol. Endocrinol , vol.16 , pp. 24-32
    • Flamant, F.1
  • 34
    • 0034639343 scopus 로고    scopus 로고
    • Expression of thyrotropin-releasing hormone receptor 2 (TRH-R2) in the central nervous system of rats
    • Heuer, H., Schafer, M.K., O'Donnell, D., Walker, P., and Bauer, K. 2000. Expression of thyrotropin-releasing hormone receptor 2 (TRH-R2) in the central nervous system of rats. J. Comp. Neurol. 428:319-336.
    • (2000) J. Comp. Neurol , vol.428 , pp. 319-336
    • Heuer, H.1    Schafer, M.K.2    O'Donnell, D.3    Walker, P.4    Bauer, K.5
  • 35
    • 77957064128 scopus 로고
    • In situ hybridization techniques to study processing enzyme expression at the cellular level
    • Schäfer, M.K.H., and Day, R. 1995. In situ hybridization techniques to study processing enzyme expression at the cellular level. Methods Neurosci. 23:16-44.
    • (1995) Methods Neurosci , vol.23 , pp. 16-44
    • Schäfer, M.K.H.1    Day, R.2
  • 36
    • 22144471212 scopus 로고    scopus 로고
    • Athyroid Pax8-/- mice cannot be rescued by the inactivation of thyroid hormone receptor alpha1
    • Mittag, J., et al. 2005. Athyroid Pax8-/- mice cannot be rescued by the inactivation of thyroid hormone receptor alpha1. Endocrinology. 146:3179-3184.
    • (2005) Endocrinology , vol.146 , pp. 3179-3184
    • Mittag, J.1
  • 37
    • 0344442669 scopus 로고    scopus 로고
    • Thyroid hormone induces cerebellar Purkinje cell development via the thyroid hormone receptor alpha1
    • Heuer, H., and Mason, C.A. 2003. Thyroid hormone induces cerebellar Purkinje cell development via the thyroid hormone receptor alpha1. J. Neurosci. 23:10604-10612.
    • (2003) J. Neurosci , vol.23 , pp. 10604-10612
    • Heuer, H.1    Mason, C.A.2
  • 38
    • 2542457313 scopus 로고    scopus 로고
    • Generation of thyrotropin-releasing hormone receptor 1-deficient mice as an animal model of central hypothyroidism
    • Rabeler, R., et al. 2004. Generation of thyrotropin-releasing hormone receptor 1-deficient mice as an animal model of central hypothyroidism. Mol. Endocrinol. 18:1450-1460.
    • (2004) Mol. Endocrinol , vol.18 , pp. 1450-1460
    • Rabeler, R.1
  • 39
    • 0037370458 scopus 로고    scopus 로고
    • Regulation of iodothyronine deiodinases in the pax8-/- mouse model of congenital hypothyroidism
    • Friedrichsen, S., et al. 2003. Regulation of iodothyronine deiodinases in the pax8-/- mouse model of congenital hypothyroidism. Endocrinology. 144:777-784.
    • (2003) Endocrinology , vol.144 , pp. 777-784
    • Friedrichsen, S.1
  • 41
    • 33747590148 scopus 로고    scopus 로고
    • Tissue-specific thyroid hormone deprivation and excess in monocarboxylate transporter (mct) 8-deficient mice
    • Dumitrescu, A.M., Liao, X.H., Weiss, R.E., Millen, K., and Refetoff, S. 2006. Tissue-specific thyroid hormone deprivation and excess in monocarboxylate transporter (mct) 8-deficient mice. Endocrinology. 147:4036-4043.
    • (2006) Endocrinology , vol.147 , pp. 4036-4043
    • Dumitrescu, A.M.1    Liao, X.H.2    Weiss, R.E.3    Millen, K.4    Refetoff, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.