Essential molecular determinants for thyroid hormone transport and first structural implications for monocarboxylate transporter 8

Journal of Biological Chemistry

Volumn 285, Issue 36, 2010, Pages 28054-28063

  Kinne, Anita ^a   Kleinau, Gunnar ^a,b   Hoefig, Carolin S ^a   Grüters, Annette ^a   Köhrle, Josef ^a   Krause, Gerd ^b   Schweizer, Ulrich ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOINFORMATICS; CELL MEMBRANES; COMPETITION; HORMONES; IODINE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; ORGANIC ACIDS; PLANTS (BOTANY); PROTEINS;

ALANINE MUTATIONS; AMINO GROUP; AROMATIC RINGS; CHIRAL CENTERS; FLAVONOIDS; GAIN INSIGHT; HOMOLOGY MODELS; IODINE ATOMS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; MAJOR FACILITATOR; MOLECULAR DETERMINANTS; PLASMA MEMBRANES; STRUCTURAL INFORMATION; STRUCTURE-FUNCTION RELATION; SUBSTRATE INTERACTION; SUBSTRATE RECOGNITION; THYROID HORMONES; TRANSFECTED CELLS; TRANSMEMBRANE TRANSPORT; TRANSMEMBRANES; TRANSPORT ACTIVITY; TRANSTHYRETIN;

SUBSTRATES;

ARGININE; ASPARAGINE; DIIODOTHYRONINE; MONOCARBOXYLATE TRANSPORTER 8; NARINGENIN; POLYPHENOL; PREALBUMIN; THYROID HORMONE; THYRONINE; 3,3',5' TRIIODOTHYRONINE; MONOCARBOXYLATE TRANSPORTER; SLC16A2 PROTEIN, HUMAN;

ARTICLE; BIOTINYLATION; CHIRALITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; SITE DIRECTED MUTAGENESIS; WESTERN BLOTTING; AMINO ACID SEQUENCE; ANIMAL; BINDING COMPETITION; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR GENETICS; MOUSE; MUTATION; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

AMINO ACID SEQUENCE; ANIMALS; BINDING, COMPETITIVE; BIOLOGICAL TRANSPORT; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MONOCARBOXYLIC ACID TRANSPORTERS; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; THYROID HORMONES; TRIIODOTHYRONINE, REVERSE;

EID: 77956246269     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.129577     Document Type: Article

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