-
1
-
-
0037427972
-
The superfamily of organic anion transporting polypeptides
-
Hagenbuch B, Meier PJ 2003 The superfamily of organic anion transporting polypeptides. Biochim Biophys Acta 1609:1-18
-
(2003)
Biochim Biophys Acta
, vol.1609
, pp. 1-18
-
-
Hagenbuch, B.1
Meier, P.J.2
-
2
-
-
16544374913
-
The organic anion transporter (OATP) family
-
Mikkaichi T, Suzuki T, Tanemoto M, Ito S, Abe T 2004 The organic anion transporter (OATP) family. Drug Metab Pharmacokinet 19:171-179
-
(2004)
Drug Metab Pharmacokinet
, vol.19
, pp. 171-179
-
-
Mikkaichi, T.1
Suzuki, T.2
Tanemoto, M.3
Ito, S.4
Abe, T.5
-
3
-
-
57349180438
-
Expression of the thyroid hormone transporters monocarboxylate transporter-8 (SLC16A2) and organic ion transporter-14 (SLCO1C1) at the blood-brain barrier
-
Roberts LM, Woodford K, Zhou M, Black DS, Haggerty JE, Tate EH, Grindstaff KK, Mengesha W, Raman C, Zerangue N 2008 Expression of the thyroid hormone transporters monocarboxylate transporter-8 (SLC16A2) and organic ion transporter-14 (SLCO1C1) at the blood-brain barrier. Endocrinology 149:6251-6261
-
(2008)
Endocrinology
, vol.149
, pp. 6251-6261
-
-
Roberts, L.M.1
Woodford, K.2
Zhou, M.3
Black, D.S.4
Haggerty, J.E.5
Tate, E.H.6
Grindstaff, K.K.7
Mengesha, W.8
Raman, C.9
Zerangue, N.10
-
4
-
-
0242384851
-
Functional characterization of rat brain-specific organic anion transporter (Oatp14) at the blood-brain barrier: High affinity transporter for thyroxine
-
Sugiyama D, Kusuhara H, Taniguchi H, Ishikawa S, Nozaki Y, Aburatani H, Sugiyama Y 2003 Functional characterization of rat brain-specific organic anion transporter (Oatp14) at the blood-brain barrier: high affinity transporter for thyroxine. J Biol Chem 278:43489-43495
-
(2003)
J Biol Chem
, vol.278
, pp. 43489-43495
-
-
Sugiyama, D.1
Kusuhara, H.2
Taniguchi, H.3
Ishikawa, S.4
Nozaki, Y.5
Aburatani, H.6
Sugiyama, Y.7
-
5
-
-
4344581457
-
Involvement of multispecific organic anion transporter, Oatp14 (Slc21a14), in the transport of thyroxine across the blood-brain barrier
-
Tohyama K, Kusuhara H, Sugiyama Y 2004 Involvement of multispecific organic anion transporter, Oatp14 (Slc21a14), in the transport of thyroxine across the blood-brain barrier. Endocrinology 145:4384-4391
-
(2004)
Endocrinology
, vol.145
, pp. 4384-4391
-
-
Tohyama, K.1
Kusuhara, H.2
Sugiyama, Y.3
-
6
-
-
34249981138
-
Cellular entry of thyroid hormones by organic anion transporting polypeptides
-
Hagenbuch B 2007 Cellular entry of thyroid hormones by organic anion transporting polypeptides. Best Pract Res 21:209-221
-
(2007)
Best Pract Res
, vol.21
, pp. 209-221
-
-
Hagenbuch, B.1
-
7
-
-
48749112588
-
Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family
-
Hagenbuch B, Gui C 2008 Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family. Xenobiotica 38:778-801
-
(2008)
Xenobiotica
, vol.38
, pp. 778-801
-
-
Hagenbuch, B.1
Gui, C.2
-
8
-
-
70350279309
-
The blood-brain barrier thyroxine transporter organic anion-transporting polypeptide 1c1 displays atypical transport kinetics
-
Westholm DE, Salo DR, Viken KJ, Rumbley JN, Anderson GW 2009 The blood-brain barrier thyroxine transporter organic anion-transporting polypeptide 1c1 displays atypical transport kinetics. Endocrinology 150:5153-5162
-
(2009)
Endocrinology
, vol.150
, pp. 5153-5162
-
-
Westholm, D.E.1
Salo, D.R.2
Viken, K.J.3
Rumbley, J.N.4
Anderson, G.W.5
-
9
-
-
0041353145
-
Structure and mechanism of the lactose permease of Escherichia coli
-
(New York, NY)
-
Abramson J, Smirnova I, Kasho V, Verner G, Kaback HR, Iwata S 2003 Structure and mechanism of the lactose permease of Escherichia coli. Science (New York, NY) 301:610-615
-
(2003)
Science
, vol.301
, pp. 610-615
-
-
Abramson, J.1
Smirnova, I.2
Kasho, V.3
Verner, G.4
Kaback, H.R.5
Iwata, S.6
-
10
-
-
33646442476
-
Organic anion transporting polypeptides of the OATP/SLCO superfamily: Identification of new members in nonmammalian species, comparative modeling and a potential transport mode
-
Meier-Abt F, Mokrab Y, Mizuguchi K 2005 Organic anion transporting polypeptides of the OATP/SLCO superfamily: identification of new members in nonmammalian species, comparative modeling and a potential transport mode. J Membr Biol 208:213-227
-
(2005)
J Membr Biol
, vol.208
, pp. 213-227
-
-
Meier-Abt, F.1
Mokrab, Y.2
Mizuguchi, K.3
-
11
-
-
0041489951
-
Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli
-
(New York, NY)
-
Huang Y, Lemieux MJ, Song J, Auer M, Wang DN 2003 Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli. Science (New York, NY) 301:616-620
-
(2003)
Science
, vol.301
, pp. 616-620
-
-
Huang, Y.1
Lemieux, M.J.2
Song, J.3
Auer, M.4
Wang, D.N.5
-
12
-
-
33646445156
-
Structure of the multidrug transporter EmrD from Escherichia coli
-
(New York, NY)
-
Yin Y, He X, Szewczyk P, Nguyen T, Chang G 2006 Structure of the multidrug transporter EmrD from Escherichia coli. Science (New York, NY) 312:741-744
-
(2006)
Science
, vol.312
, pp. 741-744
-
-
Yin, Y.1
He, X.2
Szewczyk, P.3
Nguyen, T.4
Chang, G.5
-
13
-
-
59649083811
-
Competitive inhibition of organic anion transporting polypeptide 1c1-mediated thyroxine transport by the fenamate class of nonsteroidal antiinflammatory drugs
-
Westholm DE, Stenehjem DD, Rumbley JN, Drewes LR, Anderson GW 2009 Competitive inhibition of organic anion transporting polypeptide 1c1-mediated thyroxine transport by the fenamate class of nonsteroidal antiinflammatory drugs. Endocrinology 150:1025-1032
-
(2009)
Endocrinology
, vol.150
, pp. 1025-1032
-
-
Westholm, D.E.1
Stenehjem, D.D.2
Rumbley, J.N.3
Drewes, L.R.4
Anderson, G.W.5
-
14
-
-
34248532415
-
PROMALS: Towards accurate multiple sequence alignments of distantly related proteins
-
(Oxford, England)
-
Pei J, Grishin NV 2007 PROMALS: towards accurate multiple sequence alignments of distantly related proteins. Bioinformatics (Oxford, England) 23:802-808
-
(2007)
Bioinformatics
, vol.23
, pp. 802-808
-
-
Pei, J.1
Grishin, N.V.2
-
15
-
-
0036557845
-
Basic charge clusters and predictions of membrane protein topology
-
Juretić D, Zoranić L, Zucić D 2002 Basic charge clusters and predictions of membrane protein topology. J Chem Inf Comput Sci 42:620-632
-
(2002)
J Chem Inf Comput Sci
, vol.42
, pp. 620-632
-
-
Juretić, D.1
Zoranić, L.2
Zucić, D.3
-
16
-
-
0347093547
-
TM or not TM: Transmembrane protein prediction with low false positive rate using DAS-TMfilter
-
(Oxford, England)
-
Cserzo M, Eisenhaber F, Eisenhaber B, Simon I 2004 TM or not TM: transmembrane protein prediction with low false positive rate using DAS-TMfilter. Bioinformatics (Oxford, England) 20:136-137
-
(2004)
Bioinformatics
, vol.20
, pp. 136-137
-
-
Cserzo, M.1
Eisenhaber, F.2
Eisenhaber, B.3
Simon, I.4
-
17
-
-
0041620242
-
BPROMPT: A consensus server for membrane protein prediction
-
Taylor PD, Attwood TK, Flower DR 2003 BPROMPT: a consensus server for membrane protein prediction. Nucleic Acids Res 31:3698-3700
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 3698-3700
-
-
Taylor, P.D.1
Attwood, T.K.2
Flower, D.R.3
-
18
-
-
34047151404
-
Improving the accuracy of transmembrane protein topology prediction using evolutionary information
-
(Oxford, England)
-
Jones DT 2007 Improving the accuracy of transmembrane protein topology prediction using evolutionary information. Bioinformatics (Oxford, England) 23:538-544
-
(2007)
Bioinformatics
, vol.23
, pp. 538-544
-
-
Jones, D.T.1
-
19
-
-
0034786532
-
The HMMTOP transmembrane topology prediction server
-
(Oxford, England)
-
Tusnády GE, Simon I 2001 The HMMTOP transmembrane topology prediction server. Bioinformatics (Oxford, England) 17:849-850
-
(2001)
Bioinformatics
, vol.17
, pp. 849-850
-
-
Tusnády, G.E.1
Simon, I.2
-
20
-
-
33847155026
-
Algorithms for incorporating prior topological information in HMMs: Application to transmembrane proteins
-
Bagos PG, Liakopoulos TD, Hamodrakas SJ 2006 Algorithms for incorporating prior topological information in HMMs: application to transmembrane proteins. BMC Bioinformatics 7:189
-
(2006)
BMC Bioinformatics
, vol.7
, pp. 189
-
-
Bagos, P.G.1
Liakopoulos, T.D.2
Hamodrakas, S.J.3
-
21
-
-
2142657817
-
A combined transmembrane topology and signal peptide prediction method
-
Käll L, Krogh A, Sonnhammer EL 2004 A combined transmembrane topology and signal peptide prediction method. J Mol Biol 338:1027-1036
-
(2004)
J Mol Biol
, vol.338
, pp. 1027-1036
-
-
Käll, L.1
Krogh, A.2
Sonnhammer, E.L.3
-
22
-
-
29144483361
-
An HMM posterior decoder for sequence feature prediction that includes homology information
-
(Oxford, England)
-
Kall L, Krogh A, Sonnhammer EL 2005 An HMM posterior decoder for sequence feature prediction that includes homology information. Bioinformatics (Oxford, England) 21(Suppl 1):i251-i257
-
(2005)
Bioinformatics
, vol.21
, Issue.SUPPL. 1
-
-
Kall, L.1
Krogh, A.2
Sonnhammer, E.L.3
-
23
-
-
0034518145
-
T(E)Xtopo: Shaded membrane protein topology plots in LAT(E)X2epsilon
-
(Oxford, England)
-
Beitz E 2000 T(E)Xtopo: shaded membrane protein topology plots in LAT(E)X2epsilon. Bioinformatics (Oxford, England) 16:1050-1051
-
(2000)
Bioinformatics
, vol.16
, pp. 1050-1051
-
-
Beitz, E.1
-
24
-
-
0027136282
-
Comparative protein modelling by satisfaction of spatial restraints
-
Sali A, Blundell TL 1993 Comparative protein modelling by satisfaction of spatial restraints. J Mol Biol 234:779-815
-
(1993)
J Mol Biol
, vol.234
, pp. 779-815
-
-
Sali, A.1
Blundell, T.L.2
-
25
-
-
42449090264
-
PROMALS3D: A tool for multiple protein sequence and structure alignments
-
Pei J, Kim BH, Grishin NV 2008 PROMALS3D: a tool for multiple protein sequence and structure alignments. Nucleic Acids Res 36:2295-2300
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 2295-2300
-
-
Pei, J.1
Kim, B.H.2
Grishin, N.V.3
-
26
-
-
4444221565
-
UCSF Chimera - A visualization system for exploratory research and analysis
-
Pettersen EF, Goddard TD, Huang CC, Couch GS, Greenblatt DM, Meng EC, Ferrin TE 2004 UCSF Chimera - a visualization system for exploratory research and analysis. J Comput Chem 25:1605-1612
-
(2004)
J Comput Chem
, vol.25
, pp. 1605-1612
-
-
Pettersen, E.F.1
Goddard, T.D.2
Huang, C.C.3
Couch, G.S.4
Greenblatt, D.M.5
Meng, E.C.6
Ferrin, T.E.7
-
27
-
-
34447253999
-
Sugar transport across lactose permease probed by steered molecular dynamics
-
Jensen MØ, Yin Y, Tajkhorshid E, Schulten K 2007 Sugar transport across lactose permease probed by steered molecular dynamics. Biophys J 93:92-102
-
(2007)
Biophys J
, vol.93
, pp. 92-102
-
-
Jensen, M.Ø.1
Yin, Y.2
Tajkhorshid, E.3
Schulten, K.4
-
28
-
-
33947132573
-
Sugar binding in lactose permease: Anomeric state of a disaccharide influences binding structure
-
Klauda JB, Brooks BR 2007 Sugar binding in lactose permease: anomeric state of a disaccharide influences binding structure. J Mol Biol 367:1523-1534
-
(2007)
J Mol Biol
, vol.367
, pp. 1523-1534
-
-
Klauda, J.B.1
Brooks, B.R.2
-
29
-
-
70349588813
-
Structural basis of substrate selectivity in the glycerol-3-phosphate: Phosphate antiporter GlpT
-
Law CJ, Enkavi G, Wang DN, Tajkhorshid E 2009 Structural basis of substrate selectivity in the glycerol-3-phosphate: phosphate antiporter GlpT. Biophys J 97:1346-1353
-
(2009)
Biophys J
, vol.97
, pp. 1346-1353
-
-
Law, C.J.1
Enkavi, G.2
Wang, D.N.3
Tajkhorshid, E.4
-
30
-
-
0345863729
-
Drug binding domains of MRP1 (ABCC1) as revealed by photoaffinity labeling
-
Karwatsky JM, Georges E 2004 Drug binding domains of MRP1 (ABCC1) as revealed by photoaffinity labeling. Curr Med Chem 4:19-30
-
(2004)
Curr Med Chem
, vol.4
, pp. 19-30
-
-
Karwatsky, J.M.1
Georges, E.2
-
31
-
-
63449139456
-
Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding
-
(New York, NY)
-
Aller SG, Yu J, Ward A, Weng Y, Chittaboina S, Zhuo R, Harrell PM, Trinh YT, Zhang Q, Urbatsch IL, Chang G 2009 Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science (New York, NY) 323:1718-1722
-
(2009)
Science
, vol.323
, pp. 1718-1722
-
-
Aller, S.G.1
Yu, J.2
Ward, A.3
Weng, Y.4
Chittaboina, S.5
Zhuo, R.6
Harrell, P.M.7
Trinh, Y.T.8
Zhang, Q.9
Urbatsch, I.L.10
Chang, G.11
-
32
-
-
0035940473
-
Evidence for simultaneous binding of dissimilar substrates by the Escherichia coli multidrug transporter MdfA
-
Lewinson O, Bibi E 2001 Evidence for simultaneous binding of dissimilar substrates by the Escherichia coli multidrug transporter MdfA. Biochemistry 40:12612-12618
-
(2001)
Biochemistry
, vol.40
, pp. 12612-12618
-
-
Lewinson, O.1
Bibi, E.2
-
33
-
-
0033524927
-
Bioenergetics of the staphylococcal multidrug export protein QacA. Identification of distinct binding sites for monovalent and divalent cations
-
Mitchell BA, Paulsen IT, Brown MH, Skurray RA 1999 Bioenergetics of the staphylococcal multidrug export protein QacA. Identification of distinct binding sites for monovalent and divalent cations. J Biol Chem 274:3541-3548
-
(1999)
J Biol Chem
, vol.274
, pp. 3541-3548
-
-
Mitchell, B.A.1
Paulsen, I.T.2
Brown, M.H.3
Skurray, R.A.4
-
34
-
-
0345035518
-
The secondary multidrug transporter LmrP contains multiple drug interaction sites
-
Putman M, Koole LA, van Veen HW, Konings WN 1999 The secondary multidrug transporter LmrP contains multiple drug interaction sites. Biochemistry 38:13900-13905
-
(1999)
Biochemistry
, vol.38
, pp. 13900-13905
-
-
Putman, M.1
Koole, L.A.2
Van Veen, H.W.3
Konings, W.N.4
-
35
-
-
1242272736
-
Organic anion transporting polypeptides of the OATP/ SLC21 family: Phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties
-
Hagenbuch B, Meier PJ 2004 Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties. Pflugers Arch 447:653-665
-
(2004)
Pflugers Arch
, vol.447
, pp. 653-665
-
-
Hagenbuch, B.1
Meier, P.J.2
-
36
-
-
0242405514
-
Ion channel gating: Insights via molecular simulations
-
Beckstein O, Biggin PC, Bond P, Bright JN, Domene C, Grottesi A, Holyoake J, Sansom MS 2003 Ion channel gating: insights via molecular simulations. FEBS Lett 555:85-90
-
(2003)
FEBS Lett
, vol.555
, pp. 85-90
-
-
Beckstein, O.1
Biggin, P.C.2
Bond, P.3
Bright, J.N.4
Domene, C.5
Grottesi, A.6
Holyoake, J.7
Sansom, M.S.8
-
37
-
-
25444499137
-
Importance of the GP dipeptide of the antiporter motif and other membrane-embedded proline and glycine residues in tetracycline efflux protein Tet(L)
-
De Jesus M, Jin J, Guffanti AA, Krulwich TA 2005 Importance of the GP dipeptide of the antiporter motif and other membrane-embedded proline and glycine residues in tetracycline efflux protein Tet(L). Biochemistry 44:12896-12904
-
(2005)
Biochemistry
, vol.44
, pp. 12896-12904
-
-
De Jesus, M.1
Jin, J.2
Guffanti, A.A.3
Krulwich, T.A.4
-
38
-
-
0034327611
-
Hinges, swivels and switches: The role of prolines in signalling via transmembrane α-helices
-
Sansom MS, Weinstein H 2000 Hinges, swivels and switches: the role of prolines in signalling via transmembrane α-helices. Trends Pharmacol Sci 21:445-451
-
(2000)
Trends Pharmacol Sci
, vol.21
, pp. 445-451
-
-
Sansom, M.S.1
Weinstein, H.2
-
39
-
-
10444261195
-
Application of QSAR analysis to organic anion transporting polypeptide 1a5 (Oatp1a5) substrates
-
Yarim M, Moro S, Huber R, Meier PJ, Kaseda C, Kashima T, Hagenbuch B, Folkers G 2005 Application of QSAR analysis to organic anion transporting polypeptide 1a5 (Oatp1a5) substrates. Bioorg Med Chem 13:463-471
-
(2005)
Bioorg Med Chem
, vol.13
, pp. 463-471
-
-
Yarim, M.1
Moro, S.2
Huber, R.3
Meier, P.J.4
Kaseda, C.5
Kashima, T.6
Hagenbuch, B.7
Folkers, G.8
-
40
-
-
10644282958
-
Two perfectly conserved arginine residues are required for substrate binding in a high-affinity nitrate transporter
-
Unkles SE, Rouch DA, Wang Y, Siddiqi MY, Glass AD, Kinghorn JR 2004 Two perfectly conserved arginine residues are required for substrate binding in a high-affinity nitrate transporter. Proc Natl Acad Sci USA 101:17549-17554
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 17549-17554
-
-
Unkles, S.E.1
Rouch, D.A.2
Wang, Y.3
Siddiqi, M.Y.4
Glass, A.D.5
Kinghorn, J.R.6
-
41
-
-
58949104204
-
Helix dynamics in a membrane transport protein: Comparative simulations of the glycerol-3-phosphate transporter and its constituent helices
-
D'Rozario RS, Sansom MS 2008 Helix dynamics in a membrane transport protein: comparative simulations of the glycerol-3-phosphate transporter and its constituent helices. Mol Membr Biol 25:571-583
-
(2008)
Mol Membr Biol
, vol.25
, pp. 571-583
-
-
D'Rozario, R.S.1
Sansom, M.S.2
-
44
-
-
53549085312
-
Polymorphisms in the brain-specific thyroid hormone transporter OATP1C1 are associated with fatigue and depression in hypothyroid patients
-
(Oxf)
-
van der Deure WM, Appelhof BC, Peeters RP, Wiersinga WM, Wekking EM, Huyser J, Schene AH, Tijssen JG, Hoogendijk WJ, Visser TJ, Fliers E 2008 Polymorphisms in the brain-specific thyroid hormone transporter OATP1C1 are associated with fatigue and depression in hypothyroid patients. Clin Endocrinol (Oxf) 69:804-811
-
(2008)
Clin Endocrinol
, vol.69
, pp. 804-811
-
-
Van Der Deure, W.M.1
Appelhof, B.C.2
Peeters, R.P.3
Wiersinga, W.M.4
Wekking, E.M.5
Huyser, J.6
Schene, A.H.7
Tijssen, J.G.8
Hoogendijk, W.J.9
Visser, T.J.10
Fliers, E.11
-
45
-
-
53249107832
-
Thyroid hormone transport and metabolism by organic anion transporter 1C1 and consequences of genetic variation
-
van der Deure WM, Hansen PS, Peeters RP, Kyvik KO, Friesema EC, Hegedüs L, Visser TJ 2008 Thyroid hormone transport and metabolism by organic anion transporter 1C1 and consequences of genetic variation. Endocrinology 149:5307-5314
-
(2008)
Endocrinology
, vol.149
, pp. 5307-5314
-
-
Van Der Deure, W.M.1
Hansen, P.S.2
Peeters, R.P.3
Kyvik, K.O.4
Friesema, E.C.5
Hegedüs, L.6
Visser, T.J.7
-
46
-
-
33747590985
-
Functional analysis of the extracellular cysteine residues in the human organic anion transporting polypeptide, OATP2B1
-
Hänggi E, Grundschober AF, Leuthold S, Meier PJ, St-Pierre MV 2006 Functional analysis of the extracellular cysteine residues in the human organic anion transporting polypeptide, OATP2B1. Mol Pharmacol 70:806-817
-
(2006)
Mol Pharmacol
, vol.70
, pp. 806-817
-
-
Hänggi, E.1
Grundschober, A.F.2
Leuthold, S.3
Meier, P.J.4
St-Pierre, M.V.5
-
47
-
-
50849142229
-
Amino acid residues in transmembrane domain 10 of organic anion transporting polypeptide 1B3 are critical for cholecystokinin octapeptide transport
-
Gui C, Hagenbuch B 2008 Amino acid residues in transmembrane domain 10 of organic anion transporting polypeptide 1B3 are critical for cholecystokinin octapeptide transport. Biochemistry 47:9090-9097
-
(2008)
Biochemistry
, vol.47
, pp. 9090-9097
-
-
Gui, C.1
Hagenbuch, B.2
-
48
-
-
70350474996
-
Role of transmembrane domain 10 for the function of organic anion transporting polypeptide 1B1
-
Gui C, Hagenbuch B 2009 Role of transmembrane domain 10 for the function of organic anion transporting polypeptide 1B1. Protein Sci 18:2298-2306
-
(2009)
Protein Sci
, vol.18
, pp. 2298-2306
-
-
Gui, C.1
Hagenbuch, B.2
|