-
1
-
-
29244445502
-
53BP1 oligomerization is independent of its methylation by PRMT1
-
Adams, M.M., B. Wang, Z. Xia, J.C. Morales, X. Lu, L.A. Donehower, D.A. Bochar, S.J. Elledge, and P.B. Carpenter. 2005. 53BP1 oligomerization is independent of its methylation by PRMT1. Cell Cycle. 4:1854-1861.
-
(2005)
Cell Cycle
, vol.4
, pp. 1854-1861
-
-
Adams, M.M.1
Wang, B.2
Xia, Z.3
Morales, J.C.4
Lu, X.5
Donehower, L.A.6
Bochar, D.A.7
Elledge, S.J.8
Carpenter, P.B.9
-
2
-
-
22944462083
-
Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1
-
Bekker-Jensen, S., C. Lukas, F. Melander, J. Bartek, and J. Lukas. 2005. Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1. J. Cell Biol. 170:201-211.
-
(2005)
J. Cell Biol
, vol.170
, pp. 201-211
-
-
Bekker-Jensen, S.1
Lukas, C.2
Melander, F.3
Bartek, J.4
Lukas, J.5
-
3
-
-
0035897415
-
Regulation and localization of the Bloom syndrome protein in response to DNA damage
-
Bischof, O., S.H. Kim, J. Irving, S. Beresten, N.A. Ellis, and J. Campisi. 2001. Regulation and localization of the Bloom syndrome protein in response to DNA damage. J. Cell Biol. 153:367-380.
-
(2001)
J. Cell Biol
, vol.153
, pp. 367-380
-
-
Bischof, O.1
Kim, S.H.2
Irving, J.3
Beresten, S.4
Ellis, N.A.5
Campisi, J.6
-
4
-
-
33845666681
-
Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair
-
Botuyan, M.V., J. Lee, I.M. Ward, J.E. Kim, J.R. Thompson, J. Chen, and G. Mer. 2006. Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell. 127:1361-1373.
-
(2006)
Cell
, vol.127
, pp. 1361-1373
-
-
Botuyan, M.V.1
Lee, J.2
Ward, I.M.3
Kim, J.E.4
Thompson, J.R.5
Chen, J.6
Mer, G.7
-
5
-
-
29244437180
-
BRCA1 regulates RAD51 function in response to DNA damage and suppresses spontaneous sister chromatid replication slippage: Implications for sister chromatid cohesion, genome stability, and carcinogenesis
-
Cousineau, I., C. Abaji, and A. Belmaaza. 2005. BRCA1 regulates RAD51 function in response to DNA damage and suppresses spontaneous sister chromatid replication slippage: implications for sister chromatid cohesion, genome stability, and carcinogenesis. Cancer Res. 65:11384-11391.
-
(2005)
Cancer Res
, vol.65
, pp. 11384-11391
-
-
Cousineau, I.1
Abaji, C.2
Belmaaza, A.3
-
6
-
-
1642458364
-
Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest
-
Davies, S.L., P.S. North, A. Dart, N.D. Lakin, and I.D. Hickson. 2004. Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest. Mol. Cell. Biol. 24:1279-1291.
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 1279-1291
-
-
Davies, S.L.1
North, P.S.2
Dart, A.3
Lakin, N.D.4
Hickson, I.D.5
-
7
-
-
0036902410
-
53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer
-
DiTullio, R.A., Jr., T.A. Mochan, M. Venere, J. Bartkova, M. Sehested, J. Bartek, and T.D. Halazonetis. 2002. 53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer. Nat. Cell Biol. 4:998-1002.
-
(2002)
Nat. Cell Biol
, vol.4
, pp. 998-1002
-
-
DiTullio Jr., R.A.1
Mochan, T.A.2
Venere, M.3
Bartkova, J.4
Sehested, M.5
Bartek, J.6
Halazonetis, T.D.7
-
8
-
-
0037364415
-
RecQ helicases: Caretakers of the genome
-
Hickson, I.D. 2003. RecQ helicases: caretakers of the genome. Nat. Rev. Cancer. 3:169-178.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 169-178
-
-
Hickson, I.D.1
-
9
-
-
9244252580
-
Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
-
Huyen, Y., O. Zgheib, R.A. Ditullio Jr., V.G. Gorgoulis, P. Zacharatos, T.J. Petty, E.A. Sheston, H.S. Mellert, E.S. Stavridi, and T.D. Halazonetis. 2004. Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks. Nature. 432:406-411.
-
(2004)
Nature
, vol.432
, pp. 406-411
-
-
Huyen, Y.1
Zgheib, O.2
Ditullio Jr., R.A.3
Gorgoulis, V.G.4
Zacharatos, P.5
Petty, T.J.6
Sheston, E.A.7
Mellert, H.S.8
Stavridi, E.S.9
Halazonetis, T.D.10
-
10
-
-
0037417373
-
Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response
-
Kao, G.D., W.G. McKenna, M.G. Guenther, R.J. Muschel, M.A. Lazar, and T.J. Yen. 2003. Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response. J. Cell Biol. 160:1017-1027.
-
(2003)
J. Cell Biol
, vol.160
, pp. 1017-1027
-
-
Kao, G.D.1
McKenna, W.G.2
Guenther, M.G.3
Muschel, R.J.4
Lazar, M.A.5
Yen, T.J.6
-
11
-
-
0037468232
-
MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways
-
Lou, Z., K. Minter-Dykhouse, X. Wu, and J. Chen. 2003. MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways. Nature. 421:957-961.
-
(2003)
Nature
, vol.421
, pp. 957-961
-
-
Lou, Z.1
Minter-Dykhouse, K.2
Wu, X.3
Chen, J.4
-
12
-
-
0035049599
-
The short life span of Saccharomyces cerevisiae sgs1 and srs2 mutants is a composite of normal aging processes and mitotic arrest due to defective recombination
-
McVey, M., M. Kaeberlein, H.A. Tissenbaum, and L. Guarente. 2001. The short life span of Saccharomyces cerevisiae sgs1 and srs2 mutants is a composite of normal aging processes and mitotic arrest due to defective recombination. Genetics. 157:1531-1542.
-
(2001)
Genetics
, vol.157
, pp. 1531-1542
-
-
McVey, M.1
Kaeberlein, M.2
Tissenbaum, H.A.3
Guarente, L.4
-
13
-
-
0037772381
-
Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability
-
Morales, J.C., Z. Xia, T. Lu, M.B. Aldrich, B. Wang, C. Rosales, R.E. Kellems, W.N. Hittelman, S.J. Elledge, and P.B. Carpenter. 2003. Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability. J. Biol. Chem. 278:14971-14977.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 14971-14977
-
-
Morales, J.C.1
Xia, Z.2
Lu, T.3
Aldrich, M.B.4
Wang, B.5
Rosales, C.6
Kellems, R.E.7
Hittelman, W.N.8
Elledge, S.J.9
Carpenter, P.B.10
-
14
-
-
30744471717
-
53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis
-
Morales, J.C., S. Franco, M.M. Murphy, C.H. Bassing, K.D. Mills, M.M. Adams, N.C. Walsh, J.P. Manis, G.Z. Rassidakis, F.W. Alt, and P.B. Carpenter. 2006. 53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis. Proc. Natl. Acad. Sci. USA. 103:3310-3315.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 3310-3315
-
-
Morales, J.C.1
Franco, S.2
Murphy, M.M.3
Bassing, C.H.4
Mills, K.D.5
Adams, M.M.6
Walsh, N.C.7
Manis, J.P.8
Rassidakis, G.Z.9
Alt, F.W.10
Carpenter, P.B.11
-
15
-
-
0242298316
-
DNA helicase gene interaction network defined using synthetic lethality analyzed by microarray
-
Ooi, S.L., D.D. Shoemaker, and J.D. Boeke. 2003. DNA helicase gene interaction network defined using synthetic lethality analyzed by microarray. Nat. Genet. 35:277-286.
-
(2003)
Nat. Genet
, vol.35
, pp. 277-286
-
-
Ooi, S.L.1
Shoemaker, D.D.2
Boeke, J.D.3
-
16
-
-
0033514993
-
Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage
-
Raderschall, E., E.I. Golub, and T. Haaf. 1999. Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage. Proc. Natl. Acad. Sci. USA. 96:1921-1926.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 1921-1926
-
-
Raderschall, E.1
Golub, E.I.2
Haaf, T.3
-
17
-
-
0036155849
-
Formation of higher-order nuclear Rad51 structures is functionally linked to p21 expression and protection from DNA damage-induced apoptosis
-
Raderschall, E., A. Bazarov, J. Cao, R. Lurz, A. Smith, W. Mann, H.H. Ropers, J.M. Sedivy, E.I. Golub, E. Fritz, and T. Haaf. 2002. Formation of higher-order nuclear Rad51 structures is functionally linked to p21 expression and protection from DNA damage-induced apoptosis. J. Cell Sci. 115:153-164.
-
(2002)
J. Cell Sci
, vol.115
, pp. 153-164
-
-
Raderschall, E.1
Bazarov, A.2
Cao, J.3
Lurz, R.4
Smith, A.5
Mann, W.6
Ropers, H.H.7
Sedivy, J.M.8
Golub, E.I.9
Fritz, E.10
Haaf, T.11
-
18
-
-
0035972194
-
Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways
-
Rappold, I., K. Iwabuchi, T. Date, and J. Chen. 2001. Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways. J. Cell Biol. 153:613-620.
-
(2001)
J. Cell Biol
, vol.153
, pp. 613-620
-
-
Rappold, I.1
Iwabuchi, K.2
Date, T.3
Chen, J.4
-
19
-
-
33745872612
-
Control of translocations between highly diverged genes by Sgs1, the Saccharomyces cerevisiae homolog of the Bloom's syndrome protein
-
Schmidt, K.H., J. Wu, and R.D. Kolodner. 2006. Control of translocations between highly diverged genes by Sgs1, the Saccharomyces cerevisiae homolog of the Bloom's syndrome protein. Mol. Cell. Biol. 26:5406-5420.
-
(2006)
Mol. Cell. Biol
, vol.26
, pp. 5406-5420
-
-
Schmidt, K.H.1
Wu, J.2
Kolodner, R.D.3
-
20
-
-
0030850047
-
Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage
-
Scully, R., J. Chen, R.L. Ochs, K. Keegan, M. Hoekstra, J. Feunteun, and D.M. Livingston. 1997. Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell. 90:425-435.
-
(1997)
Cell
, vol.90
, pp. 425-435
-
-
Scully, R.1
Chen, J.2
Ochs, R.L.3
Keegan, K.4
Hoekstra, M.5
Feunteun, J.6
Livingston, D.M.7
-
21
-
-
0037416149
-
BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination
-
Sengupta, S., S.P. Linke, R. Pedeux, Q. Yang, J. Farnsworth, S.H. Garfield, K. Valerie, J.W. Shay, N.A. Ellis, B. Wasylyk, and C.C. Harris. 2003. BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination. EMBO J. 22:1210-1222.
-
(2003)
EMBO J
, vol.22
, pp. 1210-1222
-
-
Sengupta, S.1
Linke, S.P.2
Pedeux, R.3
Yang, Q.4
Farnsworth, J.5
Garfield, S.H.6
Valerie, K.7
Shay, J.W.8
Ellis, N.A.9
Wasylyk, B.10
Harris, C.C.11
-
22
-
-
4544235194
-
Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest
-
Sengupta, S., A.I. Robles, S.P. Linke, N.I. Sinogeeva, R. Zhang, R. Pedeux, I.M. Ward, A. Celeste, A. Nussenzweig, J. Chen, et al. 2004. Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest. J. Cell Biol. 166:801-813.
-
(2004)
J. Cell Biol
, vol.166
, pp. 801-813
-
-
Sengupta, S.1
Robles, A.I.2
Linke, S.P.3
Sinogeeva, N.I.4
Zhang, R.5
Pedeux, R.6
Ward, I.M.7
Celeste, A.8
Nussenzweig, A.9
Chen, J.10
-
23
-
-
0034805573
-
A novel host cell reactivation assay to assess homologous recombination capacity in human cancer cell lines
-
Slebos, R.J., and J.A. Taylor. 2001. A novel host cell reactivation assay to assess homologous recombination capacity in human cancer cell lines. Biochem. Biophys. Res. Commun. 281:212-219.
-
(2001)
Biochem. Biophys. Res. Commun
, vol.281
, pp. 212-219
-
-
Slebos, R.J.1
Taylor, J.A.2
-
24
-
-
0037673943
-
The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments
-
Veaute, X., J. Jeusset, C. Soustelle, S.C. Kowalczykowski, E. Le Cam, and F. Fabre. 2003. The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments. Nature. 423:309-312.
-
(2003)
Nature
, vol.423
, pp. 309-312
-
-
Veaute, X.1
Jeusset, J.2
Soustelle, C.3
Kowalczykowski, S.C.4
Le Cam, E.5
Fabre, F.6
-
25
-
-
0037378527
-
p53 binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice
-
Ward, I.M., K. Minn, J. van Deursen, and J. Chen. 2003. p53 binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice. Mol. Cell. Biol. 23:2556-2563.
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 2556-2563
-
-
Ward, I.M.1
Minn, K.2
van Deursen, J.3
Chen, J.4
-
26
-
-
2542463148
-
53BP1 is required for class switch recombination
-
Ward, I.M., B. Reina-San-Martin, A. Olaru, K. Minn, K. Tamada, J.S. Lau, M. Cascalho, L. Chen, A. Nussenzweig, F. Livak, et al. 2004. 53BP1 is required for class switch recombination. J. Cell Biol. 165:459-464.
-
(2004)
J. Cell Biol
, vol.165
, pp. 459-464
-
-
Ward, I.M.1
Reina-San-Martin, B.2
Olaru, A.3
Minn, K.4
Tamada, K.5
Lau, J.S.6
Cascalho, M.7
Chen, L.8
Nussenzweig, A.9
Livak, F.10
-
27
-
-
27644593844
-
53BP1 cooperates with p53 and functions as a haploinsufficient tumor suppressor in mice
-
Ward, I.M., S. Difilippantonio, K. Minn, M.D. Mueller, J.R. Molina, X. Yu, C.S. Frisk, T. Ried, A. Nussenzweig, and J. Chen. 2005. 53BP1 cooperates with p53 and functions as a haploinsufficient tumor suppressor in mice. Mol. Cell. Biol. 25:10079-10086.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 10079-10086
-
-
Ward, I.M.1
Difilippantonio, S.2
Minn, K.3
Mueller, M.D.4
Molina, J.R.5
Yu, X.6
Frisk, C.S.7
Ried, T.8
Nussenzweig, A.9
Chen, J.10
-
28
-
-
0347987856
-
The Bloom's syndrome helicase suppresses crossing over during homologous recombination
-
Wu, L., and I.D. Hickson. 2003. The Bloom's syndrome helicase suppresses crossing over during homologous recombination. Nature. 426:870-874.
-
(2003)
Nature
, vol.426
, pp. 870-874
-
-
Wu, L.1
Hickson, I.D.2
-
29
-
-
0035377356
-
Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51
-
Wu, L., S.L. Davies, N.C. Levitt, and I.D. Hickson. 2001. Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51. J. Biol. Chem. 276:19375-19381.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 19375-19381
-
-
Wu, L.1
Davies, S.L.2
Levitt, N.C.3
Hickson, I.D.4
-
30
-
-
27144503470
-
MDC1 interacts with Rad51 and facilitates homologous recombination
-
Zhang, J., Z. Ma, A. Treszezamsky, and S.N. Powell. 2005. MDC1 interacts with Rad51 and facilitates homologous recombination. Nat. Struct. Mol. Biol. 12:902-909.
-
(2005)
Nat. Struct. Mol. Biol
, vol.12
, pp. 902-909
-
-
Zhang, J.1
Ma, Z.2
Treszezamsky, A.3
Powell, S.N.4
|