Homologous recombination repair is essential for repair of vosaroxin-induced DNA double-strand breaks.

Oncotarget

Volumn 1, Issue 7, 2010, Pages 606-619

  Hawtin, Rachael Elizabeth ^a   Stockett, David Elliot ^b   Wong, Oi Kwan ^b   Lundin, Cecilia ^b   Helleday, Thomas ^b   Fox, Judith Ann ^b  

^a Sunesis Pharmaceuticals Inc   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

1,4-DIHYDRO-7-(3-METHOXY-4-METHYLAMINO-1-PYRROLIDINYL)-4-OXO-1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID; ANTINEOPLASTIC AGENT; DOXORUBICIN; NAPHTHYRIDINE DERIVATIVE; THIAZOLE DERIVATIVE; VOSAROXIN;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; CELL CYCLE S PHASE; CHO CELL; CRICETULUS; DNA DAMAGE; DNA FRAGMENTATION; DNA REPAIR; DOUBLE STRANDED DNA BREAK; DRUG EFFECT; DRUG RESISTANCE; GENETIC RECOMBINATION; GENETICS; HAMSTER; HUMAN; PHYSIOLOGY; TUMOR CELL LINE; TUMOR SUPPRESSOR GENE;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHO CELLS; CRICETINAE; CRICETULUS; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; DNA FRAGMENTATION; DNA REPAIR; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; GENES, BRCA2; HUMANS; MODELS, BIOLOGICAL; NAPHTHYRIDINES; RECOMBINATION, GENETIC; S PHASE; THIAZOLES;

EID: 79957974187     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.195     Document Type: Article

References (0)