-
1
-
-
0022495870
-
Production of acquired immunodeficiency syndromeassociated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
-
Adachi, A., et al. 1986. Production of acquired immunodeficiency syndromeassociated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J. Virol. 59:284-291.
-
(1986)
J. Virol.
, vol.59
, pp. 284-291
-
-
Adachi, A.1
-
2
-
-
0023019044
-
A microtubule-binding protein associated with membranes of the Golgi apparatus
-
Allan, V. J., and T. E. Kreis. 1986. A microtubule-binding protein associated with membranes of the Golgi apparatus. J. Cell Biol. 103:2229-2239.
-
(1986)
J. Cell Biol.
, vol.103
, pp. 2229-2239
-
-
Allan, V.J.1
Kreis, T.E.2
-
3
-
-
0035368515
-
Dynamic Nef and Nef dynamics: how structure could explain the complex activities of this small HIV protein
-
Arold, S. T., and A. S. Baur. 2001. Dynamic Nef and Nef dynamics: how structure could explain the complex activities of this small HIV protein. Trends Biochem. Sci. 26:356-363.
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 356-363
-
-
Arold, S.T.1
Baur, A.S.2
-
4
-
-
0028062729
-
Physical interaction of the HIV-1 Nef protein wih β-cop, a component of non-clathrin coated vesicles essential for membrane traffic
-
Benichou, S., et al. 1994. Physical interaction of the HIV-1 Nef protein wih β-cop, a component of non-clathrin coated vesicles essential for membrane traffic. J. Biol. Chem. 269:30073-30076.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 30073-30076
-
-
Benichou, S.1
-
5
-
-
0027158904
-
Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection
-
Benson, R. E., A. Sanfridson, J. S. Ottinger, C. Doyle, and B. R. Cullen. 1993. Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection. J. Exp. Med. 177:1561-1566.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1561-1566
-
-
Benson, R.E.1
Sanfridson, A.2
Ottinger, J.S.3
Doyle, C.4
Cullen, B.R.5
-
6
-
-
2442500442
-
The functional profile of primary human antiviral CD8+ T-cell effector activity is dictated by cognate peptide concentration
-
Betts, M. R., et al. 2004. The functional profile of primary human antiviral CD8+ T-cell effector activity is dictated by cognate peptide concentration. J. Immunol. 172:6407-6417.
-
(2004)
J. Immunol.
, vol.172
, pp. 6407-6417
-
-
Betts, M.R.1
-
7
-
-
0025304819
-
Phorbol myristate acetate-induced down-modulation of CD4 is dependent on calmodulin and intracellular calcium
-
Bigby, M., P. Wang, J. F. Fierro, and M. S. Sy. 1990. Phorbol myristate acetate-induced down-modulation of CD4 is dependent on calmodulin and intracellular calcium. J. Immunol. 144:3111-3116.
-
(1990)
J. Immunol.
, vol.144
, pp. 3111-3116
-
-
Bigby, M.1
Wang, P.2
Fierro, J.F.3
Sy, M.S.4
-
8
-
-
0034854361
-
An examination of signs of disease progression in survivors of the Sydney Blood Bank Cohort (SBBC)
-
Birch, M. R., et al. 2001. An examination of signs of disease progression in survivors of the Sydney Blood Bank Cohort (SBBC). J. Clin. Virol. 22:263-270.
-
(2001)
J. Clin. Virol.
, vol.22
, pp. 263-270
-
-
Birch, M.R.1
-
9
-
-
0021955612
-
Coexpression of T4 and T8 on peripheral blood T cells demonstrated by two-color fluorescence flow cytometry
-
Blue, M. L., J. F. Daley, H. Levine, and S. F. Schlossman. 1985. Coexpression of T4 and T8 on peripheral blood T cells demonstrated by two-color fluorescence flow cytometry. J. Immunol. 134:2281-2286.
-
(1985)
J. Immunol.
, vol.134
, pp. 2281-2286
-
-
Blue, M.L.1
Daley, J.F.2
Levine, H.3
Schlossman, S.F.4
-
10
-
-
0029907407
-
Sequence requirements for the recognition of tyrosinebased endocytic signals by clathrin AP-2 complexes
-
Boll, W., et al. 1996. Sequence requirements for the recognition of tyrosinebased endocytic signals by clathrin AP-2 complexes. EMBO J. 15:5789-5795.
-
(1996)
EMBO J
, vol.15
, pp. 5789-5795
-
-
Boll, W.1
-
11
-
-
0032488027
-
A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor
-
Bresnahan, P. A., et al. 1998. A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor. Curr. Biol. 8:1235-1238.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1235-1238
-
-
Bresnahan, P.A.1
-
12
-
-
25444510358
-
The Nef protein of HIV-1 induces loss of cell surface costimulatory molecules CD80 and CD86 in APCs
-
Chaudhry, A., et al. 2005. The Nef protein of HIV-1 induces loss of cell surface costimulatory molecules CD80 and CD86 in APCs. J. Immunol. 175:4566-4574.
-
(2005)
J. Immunol.
, vol.175
, pp. 4566-4574
-
-
Chaudhry, A.1
-
14
-
-
33947715044
-
A two-pronged mechanism for HIV-1 Nef-mediated endocytosis of immune costimulatory molecules CD80 and CD86
-
Chaudhry, A., et al. 2007. A two-pronged mechanism for HIV-1 Nef-mediated endocytosis of immune costimulatory molecules CD80 and CD86. Cell Host Microbe 1:37-49.
-
(2007)
Cell Host Microbe
, vol.1
, pp. 37-49
-
-
Chaudhry, A.1
-
15
-
-
34247129671
-
Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor
-
Chaudhuri, R., O. W. Lindwasser, W. J. Smith, J. H. Hurley, and J. S. Bonifacino. 2007. Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor. J. Virol. 81:3877-3890.
-
(2007)
J. Virol.
, vol.81
, pp. 3877-3890
-
-
Chaudhuri, R.1
Lindwasser, O.W.2
Smith, W.J.3
Hurley, J.H.4
Bonifacino, J.S.5
-
16
-
-
62749181801
-
A basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex
-
Chaudhuri, R., R. Mattera, O. W. Lindwasser, M. S. Robinson, and J. S. Bonifacino. 2009. A basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex. J. Virol. 83:2518-2530.
-
(2009)
J. Virol.
, vol.83
, pp. 2518-2530
-
-
Chaudhuri, R.1
Mattera, R.2
Lindwasser, O.W.3
Robinson, M.S.4
Bonifacino, J.S.5
-
17
-
-
0029793620
-
CD4 down-modulation during infection of human T cells with human immunodeficiency virus type 1 involves independent activities of vpu, env, and nef
-
Chen, B. K., R. T. Gandhi, and D. Baltimore. 1996. CD4 down-modulation during infection of human T cells with human immunodeficiency virus type 1 involves independent activities of vpu, env, and nef. J. Virol. 70:6044-6053.
-
(1996)
J. Virol.
, vol.70
, pp. 6044-6053
-
-
Chen, B.K.1
Gandhi, R.T.2
Baltimore, D.3
-
18
-
-
32944480743
-
HIV-1 down-regulates the expression of CD1d via Nef
-
Chen, N., et al. 2006. HIV-1 down-regulates the expression of CD1d via Nef. Eur. J. Immunol. 36:278-286.
-
(2006)
Eur. J. Immunol.
, vol.36
, pp. 278-286
-
-
Chen, N.1
-
19
-
-
20444366188
-
Impaired cell surface expression of human CD1d by the formation of an HIV-1 Nef/CD1d complex
-
Cho, S., et al. 2005. Impaired cell surface expression of human CD1d by the formation of an HIV-1 Nef/CD1d complex. Virology 337:242-252.
-
(2005)
Virology
, vol.337
, pp. 242-252
-
-
Cho, S.1
-
20
-
-
4444351647
-
High levels of human immunodeficiency virus infection of CD8 lymphocytes expressing CD4 in vivo
-
Cochrane, A., et al. 2004. High levels of human immunodeficiency virus infection of CD8 lymphocytes expressing CD4 in vivo. J. Virol. 78:9862-9871.
-
(2004)
J. Virol.
, vol.78
, pp. 9862-9871
-
-
Cochrane, A.1
-
21
-
-
0033151621
-
The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells
-
Cohen, G. B., et al. 1999. The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells. Immunity 10:661-671.
-
(1999)
Immunity
, vol.10
, pp. 661-671
-
-
Cohen, G.B.1
-
22
-
-
0032556872
-
HIV-1 Nef protein protects infected primary human cells from killing by cytotoxic T lymphocytes
-
Collins, K., B. Chen, S. Kalams, B. Walker, and D. Baltimore. 1998. HIV-1 Nef protein protects infected primary human cells from killing by cytotoxic T lymphocytes. Nature 391:397-401.
-
(1998)
Nature
, vol.391
, pp. 397-401
-
-
Collins, K.1
Chen, B.2
Kalams, S.3
Walker, B.4
Baltimore, D.5
-
23
-
-
0032530773
-
Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 downregulation and optimal viral infectivity
-
Craig, H., M. Pandori, and J. Guatelli. 1998. Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 downregulation and optimal viral infectivity. Proc. Natl. Acad. Sci. U. S. A. 95:11229-11234.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 11229-11234
-
-
Craig, H.1
Pandori, M.2
Guatelli, J.3
-
24
-
-
0034713437
-
Interactions of HIV-1 nef with the mu subunits of adaptor protein complexes 1, 2, and 3: role of the dileucine-based sorting motif
-
Craig, H. M., T. R. Reddy, N. L. Riggs, P. P. Dao, and J. C. Guatelli. 2000. Interactions of HIV-1 nef with the mu subunits of adaptor protein complexes 1, 2, and 3: role of the dileucine-based sorting motif. Virology 271:9-17.
-
(2000)
Virology
, vol.271
, pp. 9-17
-
-
Craig, H.M.1
Reddy, T.R.2
Riggs, N.L.3
Dao, P.P.4
Guatelli, J.C.5
-
25
-
-
0028804160
-
Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients
-
Deacon, N. J., et al. 1995. Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients. Science 270:988-991.
-
(1995)
Science
, vol.270
, pp. 988-991
-
-
Deacon, N.J.1
-
26
-
-
34248198351
-
The gamma/ sigma1 and alpha/sigma2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site
-
Doray, B., I. Lee, J. Knisely, G. Bu, and S. Kornfeld. 2007. The gamma/ sigma1 and alpha/sigma2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site. Mol. Biol. Cell 18:1887-1896.
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 1887-1896
-
-
Doray, B.1
Lee, I.2
Knisely, J.3
Bu, G.4
Kornfeld, S.5
-
27
-
-
0030785330
-
Lymphoproliferative immune function in the Sydney Blood Bank Cohort, infected with natural nef/long terminal repeat mutants, and in other long-term survivors of transfusion-acquired HIV-1 infection
-
Dyer, W. B., et al. 1997. Lymphoproliferative immune function in the Sydney Blood Bank Cohort, infected with natural nef/long terminal repeat mutants, and in other long-term survivors of transfusion-acquired HIV-1 infection. AIDS 11:1565-1574.
-
(1997)
AIDS
, vol.11
, pp. 1565-1574
-
-
Dyer, W.B.1
-
28
-
-
0034330458
-
Two independent regions of HIV-1 Nef are required for connection with the endocytic pathway through binding to the mu 1 chain of AP1 complex
-
Erdtmann, L., et al. 2000. Two independent regions of HIV-1 Nef are required for connection with the endocytic pathway through binding to the mu 1 chain of AP1 complex. Traffic 1:871-883.
-
(2000)
Traffic
, vol.1
, pp. 871-883
-
-
Erdtmann, L.1
-
29
-
-
2942737377
-
ARF1 regulates Nef-induced CD4 degradation
-
Fauré, J., et al. 2004. ARF1 regulates Nef-induced CD4 degradation. Curr. Biol. 14:1056-1064.
-
(2004)
Curr. Biol.
, vol.14
, pp. 1056-1064
-
-
Fauré, J.1
-
30
-
-
0032539865
-
Activation of CD8+ T lymphocytes through the T-cell receptor turns on CD4 gene expression: implications for HIV pathogenesis
-
Flamand, L., et al. 1998. Activation of CD8+ T lymphocytes through the T-cell receptor turns on CD4 gene expression: implications for HIV pathogenesis. Proc. Natl. Acad. Sci. U. S. A. 95:3111-3116.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 3111-3116
-
-
Flamand, L.1
-
31
-
-
0031776457
-
A comprehensive panel of near-full-length clones and reference sequences of non-subtype B isolates of human immunodeficiency virus type 1
-
Gao, F., et al. 1998. A comprehensive panel of near-full-length clones and reference sequences of non-subtype B isolates of human immunodeficiency virus type 1. J. Virol. 72:5680-5698.
-
(1998)
J. Virol.
, vol.72
, pp. 5680-5698
-
-
Gao, F.1
-
32
-
-
0025733252
-
Serine phosphorylation-independent downregulation of cell-surface CD4 by nef
-
Garcia, J. V., and A. D. Miller. 1991. Serine phosphorylation-independent downregulation of cell-surface CD4 by nef. Nature 350:508-511.
-
(1991)
Nature
, vol.350
, pp. 508-511
-
-
Garcia, J.V.1
Miller, A.D.2
-
33
-
-
0037047282
-
Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machinery
-
Geyer, M., et al. 2002. Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machinery. J. Biol. Chem. 277:28521-28529.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 28521-28529
-
-
Geyer, M.1
-
34
-
-
0032488055
-
A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4
-
Greenberg, M., L. DeTulleo, I. Rapoport, J. Skowronski, and T. Kirchhausen. 1998. A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4. Curr. Biol. 8:1239-1242.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1239-1242
-
-
Greenberg, M.1
DeTulleo, L.2
Rapoport, I.3
Skowronski, J.4
Kirchhausen, T.5
-
35
-
-
0030684068
-
Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation
-
Greenberg, M. E., et al. 1997. Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation. EMBO J. 16:6964-6976.
-
(1997)
EMBO J
, vol.16
, pp. 6964-6976
-
-
Greenberg, M.E.1
-
36
-
-
85056049878
-
Infection of CD8+CD45RO+ memory T-cells by HIV-1 and their proliferative response
-
Gulzar, N., S. Balasubramanian, G. Harris, J. Sanchez-Dardon, and K. F. Copeland. 2008. Infection of CD8+CD45RO+ memory T-cells by HIV-1 and their proliferative response. Open AIDS J. 2:43-57.
-
(2008)
Open AIDS J
, vol.2
, pp. 43-57
-
-
Gulzar, N.1
Balasubramanian, S.2
Harris, G.3
Sanchez-Dardon, J.4
Copeland, K.F.5
-
37
-
-
58149260507
-
Proportion of HIV-1 infected CD8+CD4- T lymphocytes in vivo
-
Gulzar, N., et al. 2008. Proportion of HIV-1 infected CD8+CD4- T lymphocytes in vivo. Curr. HIV Res. 6:585-596.
-
(2008)
Curr. HIV Res.
, vol.6
, pp. 585-596
-
-
Gulzar, N.1
-
38
-
-
0036118368
-
Enumeration of the simian virus 40 early region elements necessary for human cell transformation
-
Hahn, W. C., et al. 2002. Enumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol. Cell. Biol. 22:2111-2123.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 2111-2123
-
-
Hahn, W.C.1
-
39
-
-
65449164663
-
Phenotypic and functional characterization of HIV-1-specific CD4+CD8+ double-positive T cells in early and chronic HIV-1 infection
-
Howe, R., et al. 2009. Phenotypic and functional characterization of HIV-1-specific CD4+CD8+ double-positive T cells in early and chronic HIV-1 infection. J. Acquir. Immune Defic. Syndr. 50:444-456.
-
(2009)
J. Acquir. Immune Defic. Syndr.
, vol.50
, pp. 444-456
-
-
Howe, R.1
-
40
-
-
37349065509
-
HIV-1-infected CD8+CD4+ T cells decay in vivo at a similar rate to infected CD4 T cells during HAART
-
Hughes, G. J., et al. 2008. HIV-1-infected CD8+CD4+ T cells decay in vivo at a similar rate to infected CD4 T cells during HAART. AIDS 22:57-65.
-
(2008)
AIDS
, vol.22
, pp. 57-65
-
-
Hughes, G.J.1
-
41
-
-
0035169887
-
Activated peripheral CD8 lymphocytes express CD4 in vivo and are targets for infection by human immunodeficiency virus type 1
-
Imlach, S., et al. 2001. Activated peripheral CD8 lymphocytes express CD4 in vivo and are targets for infection by human immunodeficiency virus type 1. J. Virol. 75:11555-11564.
-
(2001)
J. Virol.
, vol.75
, pp. 11555-11564
-
-
Imlach, S.1
-
42
-
-
0037424537
-
HIV-1 Nef stabilizes the association of adaptor protein complexes with membranes
-
Janvier, K., et al. 2003. HIV-1 Nef stabilizes the association of adaptor protein complexes with membranes. J. Biol. Chem. 278:8725-8732.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8725-8732
-
-
Janvier, K.1
-
43
-
-
0346102461
-
Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 gamma-sigma1 and AP-3 delta-sigma3 hemicomplexes
-
Janvier, K., et al. 2003. Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 gamma-sigma1 and AP-3 delta-sigma3 hemicomplexes. J. Cell Biol. 163:1281-1290.
-
(2003)
J. Cell Biol.
, vol.163
, pp. 1281-1290
-
-
Janvier, K.1
-
44
-
-
23844509821
-
HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent
-
Jin, Y. J., et al. 2005. HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent. J. Immunol. 175:3157-3164.
-
(2005)
J. Immunol.
, vol.175
, pp. 3157-3164
-
-
Jin, Y.J.1
-
45
-
-
0037370728
-
Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells
-
Kasper, M. R., and K. L. Collins. 2003. Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells. J. Virol. 77:3041-3049.
-
(2003)
J. Virol.
, vol.77
, pp. 3041-3049
-
-
Kasper, M.R.1
Collins, K.L.2
-
46
-
-
16844383765
-
HIV-1 Nef disrupts antigen presentation early in the secretory pathway
-
Kasper, M. R., et al. 2005. HIV-1 Nef disrupts antigen presentation early in the secretory pathway. J. Biol. Chem. 280:12840-12848.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 12840-12848
-
-
Kasper, M.R.1
-
47
-
-
57749196168
-
A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex
-
Kelly, B. T., et al. 2008. A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex. Nature 456:976-979.
-
(2008)
Nature
, vol.456
, pp. 976-979
-
-
Kelly, B.T.1
-
48
-
-
0025743306
-
Importance of the nef gene for maintenance of high virus loads and for development of AIDS
-
Kestler, H. W., III, et al. 1991. Importance of the nef gene for maintenance of high virus loads and for development of AIDS. Cell 65:651-662.
-
(1991)
Cell
, vol.65
, pp. 651-662
-
-
Kestler III, H.W.1
-
49
-
-
2942526960
-
CD4 on CD8(+) T cells directly enhances effector function and is a target for HIV infection
-
Kitchen, S. G., et al. 2004. CD4 on CD8(+) T cells directly enhances effector function and is a target for HIV infection. Proc. Natl. Acad. Sci. U. S. A. 101:8727-8732.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 8727-8732
-
-
Kitchen, S.G.1
-
50
-
-
0031660975
-
Costimulation of naive CD8(+) lymphocytes induces CD4 expression and allows human immunodeficiency virus type 1 infection
-
Kitchen, S. G., Y. D. Korin, M. D. Roth, A. Landay, and J. A. Zack. 1998. Costimulation of naive CD8(+) lymphocytes induces CD4 expression and allows human immunodeficiency virus type 1 infection. J. Virol. 72:9054-9060.
-
(1998)
J. Virol.
, vol.72
, pp. 9054-9060
-
-
Kitchen, S.G.1
Korin, Y.D.2
Roth, M.D.3
Landay, A.4
Zack, J.A.5
-
51
-
-
0033578072
-
Cell-surface expression ofCD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner
-
Lama, J., A. Mangasarian, and D. Trono. 1999. Cell-surface expression ofCD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner. Curr. Biol. 9:622-631.
-
(1999)
Curr. Biol.
, vol.9
, pp. 622-631
-
-
Lama, J.1
Mangasarian, A.2
Trono, D.3
-
52
-
-
0033839873
-
Response differences between human CD4(+) and CD8(+) T-cells during CD28 costimulation: implications for immune cellbased therapies and studies related to the expansion of double-positive T-cells during aging
-
Laux, I., et al. 2000. Response differences between human CD4(+) and CD8(+) T-cells during CD28 costimulation: implications for immune cellbased therapies and studies related to the expansion of double-positive T-cells during aging. Clin. Immunol. 96:187-197.
-
(2000)
Clin. Immunol.
, vol.96
, pp. 187-197
-
-
Laux, I.1
-
53
-
-
0032055774
-
Nef interacts with mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules
-
Le Gall, S., et al. 1998. Nef interacts with mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules. Immunity 8:483-495.
-
(1998)
Immunity
, vol.8
, pp. 483-495
-
-
Le Gall, S.1
-
54
-
-
0026667917
-
Long-term symptomless HIV-1 infection in recipients of blood products from a single donor
-
Learmont, J., et al. 1992. Long-term symptomless HIV-1 infection in recipients of blood products from a single donor. Lancet 340:863-867.
-
(1992)
Lancet
, vol.340
, pp. 863-867
-
-
Learmont, J.1
-
55
-
-
0033519616
-
Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1
-
Learmont, J. C., et al. 1999. Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1. A report from the Sydney Blood Bank Cohort. N. Engl. J. Med. 340:1715-1722.
-
(1999)
A report from the Sydney Blood Bank Cohort. N. Engl. J. Med.
, vol.340
, pp. 1715-1722
-
-
Learmont, J.C.1
-
56
-
-
0036066314
-
HIV-1 Vpr does not inhibit CTL-mediated apoptosis of HIV-1 infected cells
-
Lewinsohn, D. A., et al. 2002. HIV-1 Vpr does not inhibit CTL-mediated apoptosis of HIV-1 infected cells. Virology 294:13-21.
-
(2002)
Virology
, vol.294
, pp. 13-21
-
-
Lewinsohn, D.A.1
-
57
-
-
2442489212
-
Frequent infection of peripheral blood CD8-positive T-lymphocytes with HIV-1. Edinburgh Heterosexual Transmission Study Group
-
Livingstone, W. J., M. Moore, D. Innes, J. E. Bell, and P. Simmonds. 1996. Frequent infection of peripheral blood CD8-positive T-lymphocytes with HIV-1. Edinburgh Heterosexual Transmission Study Group. Lancet 348: 649-654.
-
(1996)
Lancet
, vol.348
, pp. 649-654
-
-
Livingstone, W.J.1
Moore, M.2
Innes, D.3
Bell, J.E.4
Simmonds, P.5
-
58
-
-
0027321768
-
Emergence of double-positive CD4/CD8 cells from adult peripheral blood mononuclear cells infected with human T-cell leukemia virus type I (HTLV-I)
-
Macchi, B., G. Graziani, J. Zhang, and A. Mastino. 1993. Emergence of double-positive CD4/CD8 cells from adult peripheral blood mononuclear cells infected with human T-cell leukemia virus type I (HTLV-I). Cell Immunol. 149:376-389.
-
(1993)
Cell Immunol
, vol.149
, pp. 376-389
-
-
Macchi, B.1
Graziani, G.2
Zhang, J.3
Mastino, A.4
-
59
-
-
0030614819
-
The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane
-
Mangasarian, A., et al. 1997. The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane. Immunity 6:67-77.
-
(1997)
Immunity
, vol.6
, pp. 67-77
-
-
Mangasarian, A.1
-
60
-
-
0033013962
-
Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-I trafficking
-
Mangasarian, A., V. Piguet, J. K. Wang, Y. L. Chen, and D. Trono. 1999. Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-I trafficking. J. Virol. 73:1964-1973.
-
(1999)
J. Virol.
, vol.73
, pp. 1964-1973
-
-
Mangasarian, A.1
Piguet, V.2
Wang, J.K.3
Chen, Y.L.4
Trono, D.5
-
61
-
-
69949128211
-
Massive secretion by T cells is caused by HIV Nef in infected cells and by Nef transfer to bystander cells
-
Muratori, C., et al. 2009. Massive secretion by T cells is caused by HIV Nef in infected cells and by Nef transfer to bystander cells. Cell Host Microbe 6:218-230.
-
(2009)
Cell Host Microbe
, vol.6
, pp. 218-230
-
-
Muratori, C.1
-
62
-
-
38349127341
-
Cooperative binding of the class I major histocompatibility complex cytoplasmic domain and human immunodeficiency virus type 1 Nef to the endosomal AP-1 complex via its mu subunit
-
Noviello, C. M., S. Benichou, and J. C. Guatelli. 2008. Cooperative binding of the class I major histocompatibility complex cytoplasmic domain and human immunodeficiency virus type 1 Nef to the endosomal AP-1 complex via its mu subunit. J. Virol. 82:1249-1258.
-
(2008)
J. Virol.
, vol.82
, pp. 1249-1258
-
-
Noviello, C.M.1
Benichou, S.2
Guatelli, J.C.3
-
63
-
-
0028840355
-
Interaction of tyrosine-based sorting signals with clathrin-associated proteins
-
Ohno, H., et al. 1995. Interaction of tyrosine-based sorting signals with clathrin-associated proteins. Science 269:1872-1875.
-
(1995)
Science
, vol.269
, pp. 1872-1875
-
-
Ohno, H.1
-
64
-
-
0027250939
-
Cytofluorimetric identification of two populations of double positive (CD4+,CD8+) T lymphocytes in human peripheral blood. Biochem
-
Ortolani, C., E. Forti, E. Radin, R. Cibin, and A. Cossarizza. 1993. Cytofluorimetric identification of two populations of double positive (CD4+,CD8+) T lymphocytes in human peripheral blood. Biochem. Biophys. Res. Commun. 191:601-609.
-
(1993)
Biophys. Res. Commun.
, vol.191
, pp. 601-609
-
-
Ortolani, C.1
Forti, E.2
Radin, E.3
Cibin, R.4
Cossarizza, A.5
-
65
-
-
1942457284
-
CD4+ CD8+ double positive (DP) T cells in health and disease
-
Parel, Y., and C. Chizzolini. 2004. CD4+ CD8+ double positive (DP) T cells in health and disease. Autoimmun. Rev. 3:215-220.
-
(2004)
Autoimmun. Rev.
, vol.3
, pp. 215-220
-
-
Parel, Y.1
Chizzolini, C.2
-
66
-
-
0027236954
-
Production of high-titer helper-free retroviruses by transient transfection
-
Pear, W. S., G. P. Nolan, M. L. Scott, and D. Baltimore. 1993. Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl. Acad. Sci. U. S. A. 90:8392-8396.
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 8392-8396
-
-
Pear, W.S.1
Nolan, G.P.2
Scott, M.L.3
Baltimore, D.4
-
67
-
-
0032079665
-
Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes
-
Piguet, V., et al. 1998. Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes. EMBO J. 17:2472-2481.
-
(1998)
EMBO J
, vol.17
, pp. 2472-2481
-
-
Piguet, V.1
-
68
-
-
0033515427
-
Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes
-
Piguet, V., et al. 1999. Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes. Cell 97:63-73.
-
(1999)
Cell
, vol.97
, pp. 63-73
-
-
Piguet, V.1
-
69
-
-
0037455578
-
Differential cellular distribution of HIV-1 drug resistance in vivo: evidence for infection of CD8+ T cells during HAART
-
Potter, S. J., D. E. Dwyer, and N. K. Saksena. 2003. Differential cellular distribution of HIV-1 drug resistance in vivo: evidence for infection of CD8+ T cells during HAART. Virology 305:339-352.
-
(2003)
Virology
, vol.305
, pp. 339-352
-
-
Potter, S.J.1
Dwyer, D.E.2
Saksena, N.K.3
-
70
-
-
33645288761
-
Human immunodeficiency virus 1 Nef suppresses CD40-dependent immunoglobulin class switching in bystander B cells
-
Qiao, X., et al. 2006. Human immunodeficiency virus 1 Nef suppresses CD40-dependent immunoglobulin class switching in bystander B cells. Nat. Immunol. 7:302-310.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 302-310
-
-
Qiao, X.1
-
71
-
-
0037422583
-
Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5
-
Qin, X. F., D. S. An, I. S. Chen, and D. Baltimore. 2003. Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc. Natl. Acad. Sci. U. S. A. 100:183-188.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 183-188
-
-
Qin, X.F.1
An, D.S.2
Chen, I.S.3
Baltimore, D.4
-
72
-
-
10344258588
-
HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail
-
Roeth, J. F., M. R. Kasper, M. Williams, T. M. Filzen, and K. L. Collins. 2004. HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail. J. Cell Biol. 167:903-913.
-
(2004)
J. Cell Biol.
, vol.167
, pp. 903-913
-
-
Roeth, J.F.1
Kasper, M.R.2
Williams, M.3
Filzen, T.M.4
Collins, K.L.5
-
73
-
-
14844322164
-
CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms
-
Rose, J. J., et al. 2005. CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms. J. Biol. Chem. 280:7413-7426.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 7413-7426
-
-
Rose, J.J.1
-
74
-
-
0033578016
-
Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein
-
Ross, T. M., A. E. Oran, and B. R. Cullen. 1999. Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein. Curr. Biol. 9:613-621.
-
(1999)
Curr. Biol.
, vol.9
, pp. 613-621
-
-
Ross, T.M.1
Oran, A.E.2
Cullen, B.R.3
-
75
-
-
0035134242
-
Isolation of primary HIV-1 that target CD8+ T lymphocytes using CD8 as a receptor
-
Saha, K., et al. 2001. Isolation of primary HIV-1 that target CD8+ T lymphocytes using CD8 as a receptor. Nat. Med. 7:65-72.
-
(2001)
Nat. Med.
, vol.7
, pp. 65-72
-
-
Saha, K.1
-
76
-
-
50949116894
-
A novel trafficking signal within the HLA-C cytoplasmic tail allows regulated expression upon differentiation of macrophages
-
Schaefer, M. R., et al. 2008. A novel trafficking signal within the HLA-C cytoplasmic tail allows regulated expression upon differentiation of macrophages. J. Immunol. 180:7804-7817.
-
(2008)
J. Immunol.
, vol.180
, pp. 7804-7817
-
-
Schaefer, M.R.1
-
77
-
-
50849129910
-
HIV-1 Nef targets MHC-I and CD4 for degradation via a final common beta-COP-dependent pathway in T cells
-
Schaefer, M. R., E. R. Wonderlich, J. F. Roeth, J. A. Leonard, and K. L. Collins. 2008. HIV-1 Nef targets MHC-I and CD4 for degradation via a final common beta-COP-dependent pathway in T cells. PLoS Pathog. 4:e1000131.
-
(2008)
PLoS Pathog
, vol.4
-
-
Schaefer, M.R.1
Wonderlich, E.R.2
Roeth, J.F.3
Leonard, J.A.4
Collins, K.L.5
-
78
-
-
0029875421
-
Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein
-
Schwartz, O., V. Marechal, S. Le Gall, F. Lemonnier, and J. Heard. 1996. Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein. Nat. Med. 2:338-342.
-
(1996)
Nat. Med.
, vol.2
, pp. 338-342
-
-
Schwartz, O.1
Marechal, V.2
Le Gall, S.3
Lemonnier, F.4
Heard, J.5
-
79
-
-
77949496852
-
An MHC-I cytoplasmic domain/HIV-1 Nef fusion protein binds directly to the mu subunit of the AP-1 endosomal coat complex
-
Singh, R. K., D. Lau, C. M. Noviello, P. Ghosh, and J. C. Guatelli. 2009. An MHC-I cytoplasmic domain/HIV-1 Nef fusion protein binds directly to the mu subunit of the AP-1 endosomal coat complex. PLoS One 4:e8364.
-
(2009)
PLoS One
, vol.4
-
-
Singh, R.K.1
Lau, D.2
Noviello, C.M.3
Ghosh, P.4
Guatelli, J.C.5
-
80
-
-
23844471509
-
Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8alphabeta
-
Stove, V., et al. 2005. Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8alphabeta. J. Virol. 79:11422-11433.
-
(2005)
J. Virol.
, vol.79
, pp. 11422-11433
-
-
Stove, V.1
-
81
-
-
0034931584
-
Upregulation of CD4 on CD8+T cells: CD4dimCD8bright T cells constitute an activated phenotype of CD8+ T cells
-
Sullivan, Y. B., A. L. Landay, J. A. Zack, S. G. Kitchen, and L. Al-Harthi. 2001. Upregulation of CD4 on CD8+T cells: CD4dimCD8bright T cells constitute an activated phenotype of CD8+ T cells. Immunology 103:270-280.
-
(2001)
Immunology
, vol.103
, pp. 270-280
-
-
Sullivan, Y.B.1
Landay, A.L.2
Zack, J.A.3
Kitchen, S.G.4
Al-Harthi, L.5
-
82
-
-
0034850037
-
CD4(+)CD8(dim) T lymphocytes exhibit enhanced cytokine expression, proliferation and cytotoxic activity in response to HCMV and HIV-1 antigens
-
Suni, M. A., et al. 2001. CD4(+)CD8(dim) T lymphocytes exhibit enhanced cytokine expression, proliferation and cytotoxic activity in response to HCMV and HIV-1 antigens. Eur. J. Immunol. 31:2512-2520.
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 2512-2520
-
-
Suni, M.A.1
-
83
-
-
0035836367
-
HIV-1 Nef blocks transport of MHC class I molecules to the cell surface via a PI 3-kinase-dependent pathway
-
Swann, S. A., et al. 2001. HIV-1 Nef blocks transport of MHC class I molecules to the cell surface via a PI 3-kinase-dependent pathway. Virology 282:267-277.
-
(2001)
Virology
, vol.282
, pp. 267-277
-
-
Swann, S.A.1
-
84
-
-
0035794535
-
Mechanism for downregulation of CD28 by Nef
-
Swigut, T., N. Shohdy, and J. Skowronski. 2001. Mechanism for downregulation of CD28 by Nef. EMBO J. 20:1593-1604.
-
(2001)
EMBO J.
, vol.20
, pp. 1593-1604
-
-
Swigut, T.1
Shohdy, N.2
Skowronski, J.3
-
85
-
-
0036314505
-
Different effects of Nef-mediated HLA class I down-regulation on human immunodeficiency virus type 1-specific CD8(+) T-cell cytolytic activity and cytokine production
-
Tomiyama, H., H. Akari, A. Adachi, and M. Takiguchi. 2002. Different effects of Nef-mediated HLA class I down-regulation on human immunodeficiency virus type 1-specific CD8(+) T-cell cytolytic activity and cytokine production. J. Virol. 76:7535-7543.
-
(2002)
J. Virol.
, vol.76
, pp. 7535-7543
-
-
Tomiyama, H.1
Akari, H.2
Adachi, A.3
Takiguchi, M.4
-
86
-
-
0028956745
-
Different domains of the AP-1 adaptor complex are required for Golgi membrane binding and clathrin recruitment
-
Traub, L. M., S. Kornfeld, and E. Ungewickell. 1995. Different domains of the AP-1 adaptor complex are required for Golgi membrane binding and clathrin recruitment. J. Biol. Chem. 270:4933-4942.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 4933-4942
-
-
Traub, L.M.1
Kornfeld, S.2
Ungewickell, E.3
-
87
-
-
0024349708
-
CD8+CD4- lymphocyte lines can harbor the AIDS virus in vitro
-
Tsubota, H., et al. 1989. CD8+CD4- lymphocyte lines can harbor the AIDS virus in vitro. J. Immunol. 143:858-863.
-
(1989)
J. Immunol.
, vol.143
, pp. 858-863
-
-
Tsubota, H.1
-
88
-
-
0033199317
-
Uncoupling IL-2 signals that regulate T-cell proliferation, survival, and Fas-mediated activation-induced cell death
-
Van Parijs, L., et al. 1999. Uncoupling IL-2 signals that regulate T-cell proliferation, survival, and Fas-mediated activation-induced cell death. Immunity 11:281-288.
-
(1999)
Immunity
, vol.11
, pp. 281-288
-
-
Van Parijs, L.1
-
89
-
-
10644261241
-
Human immunodeficiency virus type 1 Nef domains required for disruption of major histocompatibility complex class I trafficking are also necessary for coprecipitation of Nef with HLA-A2
-
Williams, M., J. F. Roeth, M. R. Kasper, T. Filzen, and K. L. Collins. 2005. Human immunodeficiency virus type 1 Nef domains required for disruption of major histocompatibility complex class I trafficking are also necessary for coprecipitation of Nef with HLA-A2. J. Virol. 79:632-636.
-
(2005)
J. Virol.
, vol.79
, pp. 632-636
-
-
Williams, M.1
Roeth, J.F.2
Kasper, M.R.3
Filzen, T.4
Collins, K.L.5
-
90
-
-
0036889125
-
Direct binding of human immunodeficiency virus type 1 Nef to the major histocompatibility complex class I (MHC-I) cytoplasmic tail disrupts MHC-I trafficking
-
Williams, M., et al. 2002. Direct binding of human immunodeficiency virus type 1 Nef to the major histocompatibility complex class I (MHC-I) cytoplasmic tail disrupts MHC-I trafficking. J. Virol. 76:12173-12184.
-
(2002)
J. Virol.
, vol.76
, pp. 12173-12184
-
-
Williams, M.1
-
91
-
-
41249090191
-
The tyrosine binding pocket in the adaptor protein 1 (AP-1) mu1 subunit is necessary for Nef to recruit AP-1 to the major histocompatibility complex class I cytoplasmic tail
-
Wonderlich, E. R., M. Williams, and K. L. Collins. 2008. The tyrosine binding pocket in the adaptor protein 1 (AP-1) mu1 subunit is necessary for Nef to recruit AP-1 to the major histocompatibility complex class I cytoplasmic tail. J. Biol. Chem. 283:3011-3022.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 3011-3022
-
-
Wonderlich, E.R.1
Williams, M.2
Collins, K.L.3
-
92
-
-
0004167774
-
Productive infection of neonatal CD8+ T lymphocytes by HIV-1
-
Yang, L. P., et al. 1998. Productive infection of neonatal CD8+ T lymphocytes by HIV-1. J. Exp. Med. 187:1139-1144.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1139-1144
-
-
Yang, L.P.1
-
93
-
-
0036146227
-
Nef-mediated resistance of human immunodeficiency virus type 1 to antiviral cytotoxic T lymphocytes
-
Yang, O. O., et al. 2002. Nef-mediated resistance of human immunodeficiency virus type 1 to antiviral cytotoxic T lymphocytes. J. Virol. 76:1626-1631.
-
(2002)
J. Virol.
, vol.76
, pp. 1626-1631
-
-
Yang, O.O.1
-
94
-
-
77957258688
-
HIV-1 Nef binds a subpopulation of MHC-I throughout its trafficking intinerary and down-regulates MHC-I by perturbing both anterograde and retrograde trafficking
-
Yi, L., et al. 2010. HIV-1 Nef binds a subpopulation of MHC-I throughout its trafficking intinerary and down-regulates MHC-I by perturbing both anterograde and retrograde trafficking. J. Biol. Chem. 285:30884-30895.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 30884-30895
-
-
Yi, L.1
-
95
-
-
0029961746
-
CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells
-
Zhou, L. J., and T. F. Tedder. 1996. CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells. Proc. Natl. Acad. Sci. U. S. A. 93:2588-2592.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 2588-2592
-
-
Zhou, L.J.1
Tedder, T.F.2
-
96
-
-
70449704423
-
Potent HIV-specific responses are enriched in a unique subset of CD8+ T cells that coexpresses CD4 on its surface
-
Zloza, A., et al. 2009. Potent HIV-specific responses are enriched in a unique subset of CD8+ T cells that coexpresses CD4 on its surface. Blood 114: 3841-3853.
-
(2009)
Blood
, vol.114
, pp. 3841-3853
-
-
Zloza, A.1
-
97
-
-
0141567584
-
CD8+ T cells that express CD4 on their surface (CD4dimCD8bright T cells) recognize an antigen-specific target, are detected in vivo, and can be productively infected by T-tropic HIV
-
Zloza, A., Y. B. Sullivan, E. Connick, A. L. Landay, and L. Al-Harthi. 2003. CD8+ T cells that express CD4 on their surface (CD4dimCD8bright T cells) recognize an antigen-specific target, are detected in vivo, and can be productively infected by T-tropic HIV. Blood 102:2156-2164.
-
(2003)
Blood
, vol.102
, pp. 2156-2164
-
-
Zloza, A.1
Sullivan, Y.B.2
Connick, E.3
Landay, A.L.4
Al-Harthi, L.5
-
98
-
-
0032738062
-
Extrathymic CD4/CD8 double positive T cells
-
Zuckermann, F. A. 1999. Extrathymic CD4/CD8 double positive T cells. Vet. Immunol. Immunopathol. 72:55-66.
-
(1999)
Vet. Immunol. Immunopathol.
, vol.72
, pp. 55-66
-
-
Zuckermann, F.A.1
|