-
1
-
-
0028180868
-
Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain
-
Aiken C., Konner J., Landau N.R., Lenburg M.E., and Trono D. Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain. Cell 76 (1994) 853-864
-
(1994)
Cell
, vol.76
, pp. 853-864
-
-
Aiken, C.1
Konner, J.2
Landau, N.R.3
Lenburg, M.E.4
Trono, D.5
-
2
-
-
0037141153
-
Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles
-
Andreola G., Rivoltini L., Castelli C., Huber V., Perego P., Deho P., Squarcina P., Accornero P., Lozupone F., Lugini L., et al. Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles. J. Exp. Med. 195 (2002) 1303-1316
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1303-1316
-
-
Andreola, G.1
Rivoltini, L.2
Castelli, C.3
Huber, V.4
Perego, P.5
Deho, P.6
Squarcina, P.7
Accornero, P.8
Lozupone, F.9
Lugini, L.10
-
3
-
-
0141780822
-
Enhanced CD4 down-modulation by late stage HIV-1 nef alleles is associated with increased Env incorporation and viral replication
-
Argañaraz E.R., Schindler M., Kirchhoff F., Cortes M.J., and Lama J. Enhanced CD4 down-modulation by late stage HIV-1 nef alleles is associated with increased Env incorporation and viral replication. J. Biol. Chem. 278 (2003) 33912-33919
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 33912-33919
-
-
Argañaraz, E.R.1
Schindler, M.2
Kirchhoff, F.3
Cortes, M.J.4
Lama, J.5
-
4
-
-
44649173294
-
HIV-1 Nef binds PACS-2 to assemble a multikinase cascade that triggers major histocompatibility complex class I (MHC-I) down-regulation: analysis using short interfering RNA and knock-out mice
-
Atkins K.M., Thomas L., Youker R.T., Harriff M.J., Pissani F., You H., and Thomas G. HIV-1 Nef binds PACS-2 to assemble a multikinase cascade that triggers major histocompatibility complex class I (MHC-I) down-regulation: analysis using short interfering RNA and knock-out mice. J. Biol. Chem. 283 (2008) 11772-11784
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 11772-11784
-
-
Atkins, K.M.1
Thomas, L.2
Youker, R.T.3
Harriff, M.J.4
Pissani, F.5
You, H.6
Thomas, G.7
-
5
-
-
0028173961
-
Effects of CD45 on NF-kappa B. Implications for replication of HIV-1
-
Baur A., Garber S., and Peterlin B.M. Effects of CD45 on NF-kappa B. Implications for replication of HIV-1. J. Immunol. 152 (1994) 976-983
-
(1994)
J. Immunol.
, vol.152
, pp. 976-983
-
-
Baur, A.1
Garber, S.2
Peterlin, B.M.3
-
6
-
-
0032530696
-
Sustained TCR signaling is required for mitogen-activated protein kinase activation and degranulation by cytotoxic T lymphocytes
-
Berg N.N., Puente L.G., Dawicki W., and Ostergaard H.L. Sustained TCR signaling is required for mitogen-activated protein kinase activation and degranulation by cytotoxic T lymphocytes. J. Immunol. 161 (1998) 2919-2924
-
(1998)
J. Immunol.
, vol.161
, pp. 2919-2924
-
-
Berg, N.N.1
Puente, L.G.2
Dawicki, W.3
Ostergaard, H.L.4
-
8
-
-
0034854361
-
An examination of signs of disease progression in survivors of the Sydney Blood Bank Cohort (SBBC)
-
Birch M.R., Learmont J.C., Dyer W.B., Deacon N.J., Zaunders J.J., Saksena N., Cunningham A.L., Mills J., and Sullivan J.S. An examination of signs of disease progression in survivors of the Sydney Blood Bank Cohort (SBBC). J. Clin. Virol. 22 (2001) 263-270
-
(2001)
J. Clin. Virol.
, vol.22
, pp. 263-270
-
-
Birch, M.R.1
Learmont, J.C.2
Dyer, W.B.3
Deacon, N.J.4
Zaunders, J.J.5
Saksena, N.6
Cunningham, A.L.7
Mills, J.8
Sullivan, J.S.9
-
9
-
-
0036533633
-
TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex
-
Blanchard N., Lankar D., Faure F., Regnault A., Dumont C., Raposo G., and Hivroz C. TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. J. Immunol. 168 (2002) 3235-3241
-
(2002)
J. Immunol.
, vol.168
, pp. 3235-3241
-
-
Blanchard, N.1
Lankar, D.2
Faure, F.3
Regnault, A.4
Dumont, C.5
Raposo, G.6
Hivroz, C.7
-
10
-
-
0032974475
-
Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells
-
Bossi G., and Griffiths G.M. Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells. Nat. Med. 5 (1999) 90-96
-
(1999)
Nat. Med.
, vol.5
, pp. 90-96
-
-
Bossi, G.1
Griffiths, G.M.2
-
11
-
-
52149109150
-
HIV-1 Nef protein is secreted into vesicles that can fuse with target cells and virions
-
S2-14-19
-
Campbell T.D., Khan M., Huang M.B., Bond V.C., and Powell M.D. HIV-1 Nef protein is secreted into vesicles that can fuse with target cells and virions. Ethn. Dis. 18 (2008) S2-14-19
-
(2008)
Ethn. Dis.
, vol.18
-
-
Campbell, T.D.1
Khan, M.2
Huang, M.B.3
Bond, V.C.4
Powell, M.D.5
-
12
-
-
25444510358
-
The Nef protein of HIV-1 induces loss of cell surface costimulatory molecules CD80 and CD86 in APCs
-
Chaudhry A., Das S.R., Hussain A., Mayor S., George A., Bal V., Jameel S., and Rath S. The Nef protein of HIV-1 induces loss of cell surface costimulatory molecules CD80 and CD86 in APCs. J. Immunol. 175 (2005) 4566-4574
-
(2005)
J. Immunol.
, vol.175
, pp. 4566-4574
-
-
Chaudhry, A.1
Das, S.R.2
Hussain, A.3
Mayor, S.4
George, A.5
Bal, V.6
Jameel, S.7
Rath, S.8
-
14
-
-
0032530773
-
Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity
-
Craig H.M., Pandori M.W., and Guatelli J.C. Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity. Proc. Natl. Acad. Sci. USA 95 (1998) 11229-11234
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 11229-11234
-
-
Craig, H.M.1
Pandori, M.W.2
Guatelli, J.C.3
-
15
-
-
0028804160
-
Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients
-
Deacon N.J., Tsykin A., Solomon A., Smith K., Ludford-Menting M., Hooker D.J., McPhee D.A., Greenway A.L., Ellett A., Chatfield C., et al. Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients. Science 270 (1995) 988-991
-
(1995)
Science
, vol.270
, pp. 988-991
-
-
Deacon, N.J.1
Tsykin, A.2
Solomon, A.3
Smith, K.4
Ludford-Menting, M.5
Hooker, D.J.6
McPhee, D.A.7
Greenway, A.L.8
Ellett, A.9
Chatfield, C.10
-
16
-
-
20044384693
-
AP-3 directs the intracellular trafficking of HIV-1 Gag and plays a key role in particle assembly
-
Dong X., Li H., Derdowski A., Ding L., Burnett A., Chen X., Peters T.R., Dermody T.S., Woodruff E., Wang J.J., and Spearman P. AP-3 directs the intracellular trafficking of HIV-1 Gag and plays a key role in particle assembly. Cell 120 (2005) 663-674
-
(2005)
Cell
, vol.120
, pp. 663-674
-
-
Dong, X.1
Li, H.2
Derdowski, A.3
Ding, L.4
Burnett, A.5
Chen, X.6
Peters, T.R.7
Dermody, T.S.8
Woodruff, E.9
Wang, J.J.10
Spearman, P.11
-
17
-
-
0031471203
-
Intercellular trafficking and protein delivery by a herpesvirus structural protein
-
Elliott G., and O'Hare P. Intercellular trafficking and protein delivery by a herpesvirus structural protein. Cell 88 (1997) 223-233
-
(1997)
Cell
, vol.88
, pp. 223-233
-
-
Elliott, G.1
O'Hare, P.2
-
18
-
-
0036230879
-
Live and let die: Nef functions beyond HIV replication
-
Fackler O.T., and Baur A.S. Live and let die: Nef functions beyond HIV replication. Immunity 16 (2002) 493-497
-
(2002)
Immunity
, vol.16
, pp. 493-497
-
-
Fackler, O.T.1
Baur, A.S.2
-
19
-
-
0033153464
-
Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions
-
Fackler O.T., Luo W., Geyer M., Alberts A.S., and Peterlin B.M. Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions. Mol. Cell 3 (1999) 729-739
-
(1999)
Mol. Cell
, vol.3
, pp. 729-739
-
-
Fackler, O.T.1
Luo, W.2
Geyer, M.3
Alberts, A.S.4
Peterlin, B.M.5
-
20
-
-
0028913261
-
Unidirectional budding of HIV-1 at the site of cell-to-cell contact is associated with co-polarization of intercellular adhesion molecules and HIV-1 viral matrix protein
-
Fais S., Capobianchi M.R., Abbate I., Castilletti C., Gentile M., Cordiali Fei P., Ameglio F., and Dianzani F. Unidirectional budding of HIV-1 at the site of cell-to-cell contact is associated with co-polarization of intercellular adhesion molecules and HIV-1 viral matrix protein. AIDS 9 (1995) 329-335
-
(1995)
AIDS
, vol.9
, pp. 329-335
-
-
Fais, S.1
Capobianchi, M.R.2
Abbate, I.3
Castilletti, C.4
Gentile, M.5
Cordiali Fei, P.6
Ameglio, F.7
Dianzani, F.8
-
21
-
-
0242333900
-
Regulation of membrane trafficking and subcellular organization of endocytic compartments revealed with FM1-43 in resting and activated human T cells
-
Fomina A.F., Deerinck T.J., Ellisman M.H., and Cahalan M.D. Regulation of membrane trafficking and subcellular organization of endocytic compartments revealed with FM1-43 in resting and activated human T cells. Exp. Cell Res. 291 (2003) 150-166
-
(2003)
Exp. Cell Res.
, vol.291
, pp. 150-166
-
-
Fomina, A.F.1
Deerinck, T.J.2
Ellisman, M.H.3
Cahalan, M.D.4
-
22
-
-
0025733252
-
Serine phosphorylation-independent downregulation of cell-surface CD4 by nef
-
Garcia J.V., and Miller A.D. Serine phosphorylation-independent downregulation of cell-surface CD4 by nef. Nature 350 (1991) 508-511
-
(1991)
Nature
, vol.350
, pp. 508-511
-
-
Garcia, J.V.1
Miller, A.D.2
-
23
-
-
2942753079
-
TCR trafficking in resting and stimulated T cells
-
Geisler C. TCR trafficking in resting and stimulated T cells. Crit. Rev. Immunol. 24 (2004) 67-86
-
(2004)
Crit. Rev. Immunol.
, vol.24
, pp. 67-86
-
-
Geisler, C.1
-
24
-
-
0024826145
-
Morphological characterization of the pathway of endocytosis and intracellular processing of transferrin and alpha-fetoprotein in human T lymphocytes stimulated with phytohemagglutinin (PHA)
-
Geuskens M., Torres J.M., Esteban C., and Uriel J. Morphological characterization of the pathway of endocytosis and intracellular processing of transferrin and alpha-fetoprotein in human T lymphocytes stimulated with phytohemagglutinin (PHA). Eur. J. Cell Biol. 50 (1989) 418-427
-
(1989)
Eur. J. Cell Biol.
, vol.50
, pp. 418-427
-
-
Geuskens, M.1
Torres, J.M.2
Esteban, C.3
Uriel, J.4
-
25
-
-
0030684068
-
Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation
-
Greenberg M.E., Bronson S., Lock M., Neumann M., Pavlakis G.N., and Skowronski J. Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation. EMBO J. 16 (1997) 6964-6976
-
(1997)
EMBO J.
, vol.16
, pp. 6964-6976
-
-
Greenberg, M.E.1
Bronson, S.2
Lock, M.3
Neumann, M.4
Pavlakis, G.N.5
Skowronski, J.6
-
27
-
-
25844482131
-
Perils at mucosal front lines for HIV and SIV and their hosts
-
Haase A.T. Perils at mucosal front lines for HIV and SIV and their hosts. Nat. Rev. Immunol. 5 (2005) 783-792
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 783-792
-
-
Haase, A.T.1
-
28
-
-
0032538278
-
Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice
-
Hanna Z., Kay D.G., Rebai N., Guimond A., Jothy S., and Jolicoeur P. Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice. Cell 95 (1998) 163-175
-
(1998)
Cell
, vol.95
, pp. 163-175
-
-
Hanna, Z.1
Kay, D.G.2
Rebai, N.3
Guimond, A.4
Jothy, S.5
Jolicoeur, P.6
-
29
-
-
32844464362
-
HIV-1 Nef mutations abrogating downregulation of CD4 affect other Nef functions and show reduced pathogenicity in transgenic mice
-
Hanna Z., Priceputu E., Hu C., Vincent P., and Jolicoeur P. HIV-1 Nef mutations abrogating downregulation of CD4 affect other Nef functions and show reduced pathogenicity in transgenic mice. Virology 346 (2006) 40-52
-
(2006)
Virology
, vol.346
, pp. 40-52
-
-
Hanna, Z.1
Priceputu, E.2
Hu, C.3
Vincent, P.4
Jolicoeur, P.5
-
30
-
-
0033615606
-
TCR-Mediated internalization of peptide-MHC complexes acquired by T cells
-
Huang J.F., Yang Y., Sepulveda H., Shi W., Hwang I., Peterson P.A., Jackson M.R., Sprent J., and Cai Z. TCR-Mediated internalization of peptide-MHC complexes acquired by T cells. Science 286 (1999) 952-954
-
(1999)
Science
, vol.286
, pp. 952-954
-
-
Huang, J.F.1
Yang, Y.2
Sepulveda, H.3
Shi, W.4
Hwang, I.5
Peterson, P.A.6
Jackson, M.R.7
Sprent, J.8
Cai, Z.9
-
31
-
-
0033775488
-
Disrupting surfaces of nef required for downregulation of CD4 and for enhancement of virion infectivity attenuates simian immunodeficiency virus replication in vivo
-
Iafrate A.J., Carl S., Bronson S., Stahl-Hennig C., Swigut T., Skowronski J., and Kirchhoff F. Disrupting surfaces of nef required for downregulation of CD4 and for enhancement of virion infectivity attenuates simian immunodeficiency virus replication in vivo. J. Virol. 74 (2000) 9836-9844
-
(2000)
J. Virol.
, vol.74
, pp. 9836-9844
-
-
Iafrate, A.J.1
Carl, S.2
Bronson, S.3
Stahl-Hennig, C.4
Swigut, T.5
Skowronski, J.6
Kirchhoff, F.7
-
32
-
-
0242515763
-
Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton
-
Igakura T., Stinchcombe J.C., Goon P.K., Taylor G.P., Weber J.N., Griffiths G.M., Tanaka Y., Osame M., and Bangham C.R. Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton. Science 299 (2003) 1713-1716
-
(2003)
Science
, vol.299
, pp. 1713-1716
-
-
Igakura, T.1
Stinchcombe, J.C.2
Goon, P.K.3
Taylor, G.P.4
Weber, J.N.5
Griffiths, G.M.6
Tanaka, Y.7
Osame, M.8
Bangham, C.R.9
-
33
-
-
0036133058
-
Directed egress of animal viruses promotes cell-to-cell spread
-
Johnson D.C., and Huber M.T. Directed egress of animal viruses promotes cell-to-cell spread. J. Virol. 76 (2002) 1-8
-
(2002)
J. Virol.
, vol.76
, pp. 1-8
-
-
Johnson, D.C.1
Huber, M.T.2
-
34
-
-
36048947746
-
Regulated secretion from CD4+ T cells
-
Jolly C., and Sattentau Q.J. Regulated secretion from CD4+ T cells. Trends Immunol. 28 (2007) 474-481
-
(2007)
Trends Immunol.
, vol.28
, pp. 474-481
-
-
Jolly, C.1
Sattentau, Q.J.2
-
35
-
-
0041381374
-
What is trogocytosis and what is its purpose?
-
Joly E., and Hudrisier D. What is trogocytosis and what is its purpose?. Nat. Immunol. 4 (2003) 815
-
(2003)
Nat. Immunol.
, vol.4
, pp. 815
-
-
Joly, E.1
Hudrisier, D.2
-
36
-
-
0025743306
-
Importance of the nef gene for maintenance of high virus loads and for development of AIDS
-
Kestler III H.W., Ringler D.J., Mori K., Panicali D.L., Sehgal P.K., Daniel M.D., and Desrosiers R.C. Importance of the nef gene for maintenance of high virus loads and for development of AIDS. Cell 65 (1991) 651-662
-
(1991)
Cell
, vol.65
, pp. 651-662
-
-
Kestler III, H.W.1
Ringler, D.J.2
Mori, K.3
Panicali, D.L.4
Sehgal, P.K.5
Daniel, M.D.6
Desrosiers, R.C.7
-
37
-
-
0346601814
-
The physiological relevance of CD4 receptor down-modulation during HIV infection
-
Lama J. The physiological relevance of CD4 receptor down-modulation during HIV infection. Curr. HIV Res. 1 (2003) 167-184
-
(2003)
Curr. HIV Res.
, vol.1
, pp. 167-184
-
-
Lama, J.1
-
38
-
-
0037114287
-
Production and characterization of clinical grade exosomes derived from dendritic cells
-
Lamparski H.G., Metha-Damani A., Yao J.Y., Patel S., Hsu D.H., Ruegg C., and Le Pecq J.B. Production and characterization of clinical grade exosomes derived from dendritic cells. J. Immunol. Methods 270 (2002) 211-226
-
(2002)
J. Immunol. Methods
, vol.270
, pp. 211-226
-
-
Lamparski, H.G.1
Metha-Damani, A.2
Yao, J.Y.3
Patel, S.4
Hsu, D.H.5
Ruegg, C.6
Le Pecq, J.B.7
-
39
-
-
0032055774
-
Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules
-
Le Gall S., Erdtmann L., Benichou S., Berlioz-Torrent C., Liu L., Benarous R., Heard J.M., and Schwartz O. Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules. Immunity 8 (1998) 483-495
-
(1998)
Immunity
, vol.8
, pp. 483-495
-
-
Le Gall, S.1
Erdtmann, L.2
Benichou, S.3
Berlioz-Torrent, C.4
Liu, L.5
Benarous, R.6
Heard, J.M.7
Schwartz, O.8
-
40
-
-
0033519616
-
Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1. A report from the Sydney Blood Bank Cohort
-
Learmont J.C., Geczy A.F., Mills J., Ashton L.J., Raynes-Greenow C.H., Garsia R.J., Dyer W.B., McIntyre L., Oelrichs R.B., Rhodes D.I., et al. Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1. A report from the Sydney Blood Bank Cohort. N. Engl. J. Med. 340 (1999) 1715-1722
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 1715-1722
-
-
Learmont, J.C.1
Geczy, A.F.2
Mills, J.3
Ashton, L.J.4
Raynes-Greenow, C.H.5
Garsia, R.J.6
Dyer, W.B.7
McIntyre, L.8
Oelrichs, R.B.9
Rhodes, D.I.10
-
41
-
-
0027955426
-
Severe immunodeficiency associated with a human immunodeficiency virus 1 NEF/3′-long terminal repeat transgene
-
Lindemann D., Wilhelm R., Renard P., Althage A., Zinkernagel R., and Mous J. Severe immunodeficiency associated with a human immunodeficiency virus 1 NEF/3′-long terminal repeat transgene. J. Exp. Med. 179 (1994) 797-807
-
(1994)
J. Exp. Med.
, vol.179
, pp. 797-807
-
-
Lindemann, D.1
Wilhelm, R.2
Renard, P.3
Althage, A.4
Zinkernagel, R.5
Mous, J.6
-
42
-
-
0030475891
-
CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1
-
Lu X., Wu X., Plemenitas A., Yu H., Sawai E.T., Abo A., and Peterlin B.M. CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1. Curr. Biol. 6 (1996) 1677-1684
-
(1996)
Curr. Biol.
, vol.6
, pp. 1677-1684
-
-
Lu, X.1
Wu, X.2
Plemenitas, A.3
Yu, H.4
Sawai, E.T.5
Abo, A.6
Peterlin, B.M.7
-
43
-
-
20044362379
-
Nef-induced alteration of the early/recycling endosomal compartment correlates with enhancement of HIV-1 infectivity
-
Madrid R., Janvier K., Hitchin D., Day J., Coleman S., Noviello C., Bouchet J., Benmerah A., Guatelli J., and Benichou S. Nef-induced alteration of the early/recycling endosomal compartment correlates with enhancement of HIV-1 infectivity. J. Biol. Chem. 280 (2005) 5032-5044
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 5032-5044
-
-
Madrid, R.1
Janvier, K.2
Hitchin, D.3
Day, J.4
Coleman, S.5
Noviello, C.6
Bouchet, J.7
Benmerah, A.8
Guatelli, J.9
Benichou, S.10
-
44
-
-
0344731338
-
Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles
-
Martínez-Lorenzo M.J., Anel A., Gamen S., Monleón I., Lasierra P., Larrad L., Piñeiro A., Alava M.A., and Naval J. Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles. J. Immunol. 163 (1999) 1274-1281
-
(1999)
J. Immunol.
, vol.163
, pp. 1274-1281
-
-
Martínez-Lorenzo, M.J.1
Anel, A.2
Gamen, S.3
Monleón, I.4
Lasierra, P.5
Larrad, L.6
Piñeiro, A.7
Alava, M.A.8
Naval, J.9
-
45
-
-
18044378256
-
The Nef protein of human immunodeficiency virus establishes superinfection immunity by a dual strategy to downregulate cell-surface CCR5 and CD4
-
Michel N., Allespach I., Venzke S., Fackler O.T., and Keppler O.T. The Nef protein of human immunodeficiency virus establishes superinfection immunity by a dual strategy to downregulate cell-surface CCR5 and CD4. Curr. Biol. 15 (2005) 714-723
-
(2005)
Curr. Biol.
, vol.15
, pp. 714-723
-
-
Michel, N.1
Allespach, I.2
Venzke, S.3
Fackler, O.T.4
Keppler, O.T.5
-
46
-
-
0035892735
-
Differential secretion of Fas ligand- or APO2 ligand/TNF-related apoptosis-inducing ligand-carrying microvesicles during activation-induced death of human T cells
-
Monleón I., Martínez-Lorenzo M.J., Monteagudo L., Lasierra P., Taules M., Iturralde M., Piñeiro A., Larrad L., Alava M.A., Naval J., and Anel A. Differential secretion of Fas ligand- or APO2 ligand/TNF-related apoptosis-inducing ligand-carrying microvesicles during activation-induced death of human T cells. J. Immunol. 167 (2001) 6736-6744
-
(2001)
J. Immunol.
, vol.167
, pp. 6736-6744
-
-
Monleón, I.1
Martínez-Lorenzo, M.J.2
Monteagudo, L.3
Lasierra, P.4
Taules, M.5
Iturralde, M.6
Piñeiro, A.7
Larrad, L.8
Alava, M.A.9
Naval, J.10
Anel, A.11
-
47
-
-
0035863013
-
Cell surface area regulation and membrane tension
-
Morris C.E., and Homann U. Cell surface area regulation and membrane tension. J. Membr. Biol. 179 (2001) 79-102
-
(2001)
J. Membr. Biol.
, vol.179
, pp. 79-102
-
-
Morris, C.E.1
Homann, U.2
-
48
-
-
0035923525
-
Plasma membrane rafts play a critical role in HIV-1 assembly and release
-
Ono A., and Freed E.O. Plasma membrane rafts play a critical role in HIV-1 assembly and release. Proc. Natl. Acad. Sci. USA 98 (2001) 13925-13930
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 13925-13930
-
-
Ono, A.1
Freed, E.O.2
-
49
-
-
0028217413
-
Role of the cytoskeleton in cell-to-cell transmission of human immunodeficiency virus
-
Pearce-Pratt R., Malamud D., and Phillips D.M. Role of the cytoskeleton in cell-to-cell transmission of human immunodeficiency virus. J. Virol. 68 (1994) 2898-2905
-
(1994)
J. Virol.
, vol.68
, pp. 2898-2905
-
-
Pearce-Pratt, R.1
Malamud, D.2
Phillips, D.M.3
-
50
-
-
0041488655
-
Infectious HIV-1 assembles in late endosomes in primary macrophages
-
Pelchen-Matthews A., Kramer B., and Marsh M. Infectious HIV-1 assembles in late endosomes in primary macrophages. J. Cell Biol. 162 (2003) 443-455
-
(2003)
J. Cell Biol.
, vol.162
, pp. 443-455
-
-
Pelchen-Matthews, A.1
Kramer, B.2
Marsh, M.3
-
51
-
-
0032079665
-
Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes
-
Piguet V., Chen Y.L., Mangasarian A., Foti M., Carpentier J.L., and Trono D. Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes. EMBO J. 17 (1998) 2472-2481
-
(1998)
EMBO J.
, vol.17
, pp. 2472-2481
-
-
Piguet, V.1
Chen, Y.L.2
Mangasarian, A.3
Foti, M.4
Carpentier, J.L.5
Trono, D.6
-
52
-
-
0032999976
-
The downregulation of CD4 and MHC-I by primate lentiviruses: a paradigm for the modulation of cell surface receptors
-
Piguet V., Schwartz O., Le Gall S., and Trono D. The downregulation of CD4 and MHC-I by primate lentiviruses: a paradigm for the modulation of cell surface receptors. Immunol. Rev. 168 (1999) 51-63
-
(1999)
Immunol. Rev.
, vol.168
, pp. 51-63
-
-
Piguet, V.1
Schwartz, O.2
Le Gall, S.3
Trono, D.4
-
53
-
-
33645924074
-
A novel PKC regulates ERK activation and degranulation of cytotoxic T lymphocytes: Plasticity in PKC regulation of ERK
-
Puente L.G., He J.S., and Ostergaard H.L. A novel PKC regulates ERK activation and degranulation of cytotoxic T lymphocytes: Plasticity in PKC regulation of ERK. Eur. J. Immunol. 36 (2006) 1009-1018
-
(2006)
Eur. J. Immunol.
, vol.36
, pp. 1009-1018
-
-
Puente, L.G.1
He, J.S.2
Ostergaard, H.L.3
-
54
-
-
33645288761
-
Human immunodeficiency virus 1 Nef suppresses CD40-dependent immunoglobulin class switching in bystander B cells
-
Qiao X., He B., Chiu A., Knowles D.M., Chadburn A., and Cerutti A. Human immunodeficiency virus 1 Nef suppresses CD40-dependent immunoglobulin class switching in bystander B cells. Nat. Immunol. 7 (2006) 302-310
-
(2006)
Nat. Immunol.
, vol.7
, pp. 302-310
-
-
Qiao, X.1
He, B.2
Chiu, A.3
Knowles, D.M.4
Chadburn, A.5
Cerutti, A.6
-
55
-
-
0029989258
-
B lymphocytes secrete antigen-presenting vesicles
-
Raposo G., Nijman H.W., Stoorvogel W., Liejendekker R., Harding C.V., Melief C.J., and Geuze H.J. B lymphocytes secrete antigen-presenting vesicles. J. Exp. Med. 183 (1996) 1161-1172
-
(1996)
J. Exp. Med.
, vol.183
, pp. 1161-1172
-
-
Raposo, G.1
Nijman, H.W.2
Stoorvogel, W.3
Liejendekker, R.4
Harding, C.V.5
Melief, C.J.6
Geuze, H.J.7
-
56
-
-
0028200761
-
Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4
-
Rhee S.S., and Marsh J.W. Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4. J. Virol. 68 (1994) 5156-5163
-
(1994)
J. Virol.
, vol.68
, pp. 5156-5163
-
-
Rhee, S.S.1
Marsh, J.W.2
-
57
-
-
29144503720
-
A role for phosphatidylinositol 3-kinase in TCR-stimulated ERK activation leading to paxillin phosphorylation and CTL degranulation
-
Robertson L.K., Mireau L.R., and Ostergaard H.L. A role for phosphatidylinositol 3-kinase in TCR-stimulated ERK activation leading to paxillin phosphorylation and CTL degranulation. J. Immunol. 175 (2005) 8138-8145
-
(2005)
J. Immunol.
, vol.175
, pp. 8138-8145
-
-
Robertson, L.K.1
Mireau, L.R.2
Ostergaard, H.L.3
-
58
-
-
1842266562
-
HIV viral load markers in clinical practice
-
Saag M.S., Holodniy M., Kuritzkes D.R., O'Brien W.A., Coombs R., Poscher M.E., Jacobsen D.M., Shaw G.M., Richman D.D., and Volberding P.A. HIV viral load markers in clinical practice. Nat. Med. 2 (1996) 625-629
-
(1996)
Nat. Med.
, vol.2
, pp. 625-629
-
-
Saag, M.S.1
Holodniy, M.2
Kuritzkes, D.R.3
O'Brien, W.A.4
Coombs, R.5
Poscher, M.E.6
Jacobsen, D.M.7
Shaw, G.M.8
Richman, D.D.9
Volberding, P.A.10
-
59
-
-
33644862821
-
Intracellular versus cell surface assembly of retroviral pseudotypes is determined by the cellular localization of the viral glycoprotein, its capacity to interact with Gag, and the expression of the Nef protein
-
Sandrin V., and Cosset F.L. Intracellular versus cell surface assembly of retroviral pseudotypes is determined by the cellular localization of the viral glycoprotein, its capacity to interact with Gag, and the expression of the Nef protein. J. Biol. Chem. 281 (2006) 528-542
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 528-542
-
-
Sandrin, V.1
Cosset, F.L.2
-
60
-
-
0037096162
-
The exosome pathway in K562 cells is regulated by Rab11
-
Savina A., Vidal M., and Colombo M.I. The exosome pathway in K562 cells is regulated by Rab11. J. Cell Sci. 115 (2002) 2505-2515
-
(2002)
J. Cell Sci.
, vol.115
, pp. 2505-2515
-
-
Savina, A.1
Vidal, M.2
Colombo, M.I.3
-
61
-
-
0034053833
-
The T-cell receptor zeta chain contains two homologous domains with which simian immunodeficiency virus Nef interacts and mediates down-modulation
-
Schaefer T.M., Bell I., Fallert B.A., and Reinhart T.A. The T-cell receptor zeta chain contains two homologous domains with which simian immunodeficiency virus Nef interacts and mediates down-modulation. J. Virol. 74 (2000) 3273-3283
-
(2000)
J. Virol.
, vol.74
, pp. 3273-3283
-
-
Schaefer, T.M.1
Bell, I.2
Fallert, B.A.3
Reinhart, T.A.4
-
62
-
-
33646145685
-
A new way to generate cytolytic tumor-specific T cells: electroporation of RNA coding for a T cell receptor into T lymphocytes
-
Schaft N., Dörrie J., Muller I., Beck V., Baumann S., Schunder T., Kämpgen E., and Schuler G. A new way to generate cytolytic tumor-specific T cells: electroporation of RNA coding for a T cell receptor into T lymphocytes. Cancer Immunol. Immunother. 55 (2005) 1-10
-
(2005)
Cancer Immunol. Immunother.
, vol.55
, pp. 1-10
-
-
Schaft, N.1
Dörrie, J.2
Muller, I.3
Beck, V.4
Baumann, S.5
Schunder, T.6
Kämpgen, E.7
Schuler, G.8
-
63
-
-
2542492063
-
HIV-1 Nef enhances both membrane expression and virion incorporation of Env products. A model for the Nef-dependent increase of HIV-1 infectivity
-
Schiavoni I., Trapp S., Santarcangelo A.C., Piacentini V., Pugliese K., Baur A., and Federico M. HIV-1 Nef enhances both membrane expression and virion incorporation of Env products. A model for the Nef-dependent increase of HIV-1 infectivity. J. Biol. Chem. 279 (2004) 22996-23006
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 22996-23006
-
-
Schiavoni, I.1
Trapp, S.2
Santarcangelo, A.C.3
Piacentini, V.4
Pugliese, K.5
Baur, A.6
Federico, M.7
-
64
-
-
0242321269
-
Regulation of G protein-coupled receptor endocytosis and trafficking by Rab GTPases
-
Seachrist J.L., and Ferguson S.S. Regulation of G protein-coupled receptor endocytosis and trafficking by Rab GTPases. Life Sci. 74 (2003) 225-235
-
(2003)
Life Sci.
, vol.74
, pp. 225-235
-
-
Seachrist, J.L.1
Ferguson, S.S.2
-
65
-
-
0037343278
-
Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia
-
Silvestri G., Sodora D.L., Koup R.A., Paiardini M., O'Neil S.P., McClure H.M., Staprans S.I., and Feinberg M.B. Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia. Immunity 18 (2003) 441-452
-
(2003)
Immunity
, vol.18
, pp. 441-452
-
-
Silvestri, G.1
Sodora, D.L.2
Koup, R.A.3
Paiardini, M.4
O'Neil, S.P.5
McClure, H.M.6
Staprans, S.I.7
Feinberg, M.B.8
-
66
-
-
0034948709
-
Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators
-
Simmons A., Aluvihare V., and McMichael A. Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators. Immunity 14 (2001) 763-777
-
(2001)
Immunity
, vol.14
, pp. 763-777
-
-
Simmons, A.1
Aluvihare, V.2
McMichael, A.3
-
67
-
-
38849168755
-
Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission
-
Sowinski S., Jolly C., Berninghausen O., Purbhoo M.A., Chauveau A., Kohler K., Oddos S., Eissmann P., Brodsky F.M., Hopkins C., et al. Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission. Nat. Cell Biol. 10 (2008) 211-219
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 211-219
-
-
Sowinski, S.1
Jolly, C.2
Berninghausen, O.3
Purbhoo, M.A.4
Chauveau, A.5
Kohler, K.6
Oddos, S.7
Eissmann, P.8
Brodsky, F.M.9
Hopkins, C.10
-
68
-
-
0037302331
-
Human immunodeficiency virus type 1 Nef-mediated downregulation of CD4 correlates with Nef enhancement of viral pathogenesis
-
Stoddart C.A., Geleziunas R., Ferrell S., Linquist-Stepps V., Moreno M.E., Bare C., Xu W., Yonemoto W., Bresnahan P.A., McCune J.M., and Greene W.C. Human immunodeficiency virus type 1 Nef-mediated downregulation of CD4 correlates with Nef enhancement of viral pathogenesis. J. Virol. 77 (2003) 2124-2133
-
(2003)
J. Virol.
, vol.77
, pp. 2124-2133
-
-
Stoddart, C.A.1
Geleziunas, R.2
Ferrell, S.3
Linquist-Stepps, V.4
Moreno, M.E.5
Bare, C.6
Xu, W.7
Yonemoto, W.8
Bresnahan, P.A.9
McCune, J.M.10
Greene, W.C.11
-
69
-
-
23844471509
-
Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8alphabeta
-
Stove V., Van de Walle I., Naessens E., Coene E., Stove C., Plum J., and Verhasselt B. Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8alphabeta. J. Virol. 79 (2005) 11422-11433
-
(2005)
J. Virol.
, vol.79
, pp. 11422-11433
-
-
Stove, V.1
Van de Walle, I.2
Naessens, E.3
Coene, E.4
Stove, C.5
Plum, J.6
Verhasselt, B.7
-
70
-
-
0035834141
-
HIV-1 Nef impairs MHC class II antigen presentation and surface expression
-
Stumptner-Cuvelette P., Morchoisne S., Dugast M., Le Gall S., Raposo G., Schwartz O., and Benaroch P. HIV-1 Nef impairs MHC class II antigen presentation and surface expression. Proc. Natl. Acad. Sci. USA 98 (2001) 12144-12149
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12144-12149
-
-
Stumptner-Cuvelette, P.1
Morchoisne, S.2
Dugast, M.3
Le Gall, S.4
Raposo, G.5
Schwartz, O.6
Benaroch, P.7
-
71
-
-
0035794535
-
Mechanism for down-regulation of CD28 by Nef
-
Swigut T., Shohdy N., and Skowronski J. Mechanism for down-regulation of CD28 by Nef. EMBO J. 20 (2001) 1593-1604
-
(2001)
EMBO J.
, vol.20
, pp. 1593-1604
-
-
Swigut, T.1
Shohdy, N.2
Skowronski, J.3
-
73
-
-
0347861844
-
In vivo analysis of Nef function
-
Wei B.L., Arora V.K., Foster J.L., Sodora D.L., and Garcia J.V. In vivo analysis of Nef function. Curr. HIV Res. 1 (2003) 41-50
-
(2003)
Curr. HIV Res.
, vol.1
, pp. 41-50
-
-
Wei, B.L.1
Arora, V.K.2
Foster, J.L.3
Sodora, D.L.4
Garcia, J.V.5
-
74
-
-
34547890698
-
Membranous structures transfer cell surface proteins across NK cell immune synapses
-
Williams G.S., Collinson L.M., Brzostek J., Eissmann P., Almeida C.R., McCann F.E., Burshtyn D., and Davis D.M. Membranous structures transfer cell surface proteins across NK cell immune synapses. Traffic 8 (2007) 1190-1204
-
(2007)
Traffic
, vol.8
, pp. 1190-1204
-
-
Williams, G.S.1
Collinson, L.M.2
Brzostek, J.3
Eissmann, P.4
Almeida, C.R.5
McCann, F.E.6
Burshtyn, D.7
Davis, D.M.8
-
75
-
-
10744228109
-
HIV-1 Nef mimics an integrin receptor signal that recruits the polycomb group protein Eed to the plasma membrane
-
Witte V., Laffert B., Rosorius O., Lischka P., Blume K., Galler G., Stilper A., Willbold D., D'Aloja P., Sixt M., et al. HIV-1 Nef mimics an integrin receptor signal that recruits the polycomb group protein Eed to the plasma membrane. Mol. Cell 13 (2004) 179-190
-
(2004)
Mol. Cell
, vol.13
, pp. 179-190
-
-
Witte, V.1
Laffert, B.2
Rosorius, O.3
Lischka, P.4
Blume, K.5
Galler, G.6
Stilper, A.7
Willbold, D.8
D'Aloja, P.9
Sixt, M.10
-
76
-
-
58849132949
-
Induction of HIV transcription by Nef involves Lck activation and protein kinase C theta raft recruitment leading to activation of ERK1/2 but not NF kappa B
-
Witte V., Laffert B., Gintschel P., Krautkramer E., Blume K., Fackler O.T., and Baur A.S. Induction of HIV transcription by Nef involves Lck activation and protein kinase C theta raft recruitment leading to activation of ERK1/2 but not NF kappa B. J. Immunol. 181 (2008) 8425-8432
-
(2008)
J. Immunol.
, vol.181
, pp. 8425-8432
-
-
Witte, V.1
Laffert, B.2
Gintschel, P.3
Krautkramer, E.4
Blume, K.5
Fackler, O.T.6
Baur, A.S.7
-
77
-
-
36549037151
-
Novel (n)PKC kinases phosphorylate Nef for increased HIV transcription, replication and perinuclear targeting
-
Wolf D., Giese S.I., Witte V., Krautkrämer E., Trapp S., Sass G., Haller C., Blume K., Fackler O.T., and Baur A.S. Novel (n)PKC kinases phosphorylate Nef for increased HIV transcription, replication and perinuclear targeting. Virology 370 (2008) 45-54
-
(2008)
Virology
, vol.370
, pp. 45-54
-
-
Wolf, D.1
Giese, S.I.2
Witte, V.3
Krautkrämer, E.4
Trapp, S.5
Sass, G.6
Haller, C.7
Blume, K.8
Fackler, O.T.9
Baur, A.S.10
-
78
-
-
53349100912
-
HIV Nef enhances Tat-mediated viral transcription through a hnRNP-K-nucleated signaling complex
-
Wolf D., Witte V., Clark P., Blume K., Lichtenheld M.G., and Baur A.S. HIV Nef enhances Tat-mediated viral transcription through a hnRNP-K-nucleated signaling complex. Cell Host Microbe 4 (2008) 398-408
-
(2008)
Cell Host Microbe
, vol.4
, pp. 398-408
-
-
Wolf, D.1
Witte, V.2
Clark, P.3
Blume, K.4
Lichtenheld, M.G.5
Baur, A.S.6
-
79
-
-
0030744349
-
Evasion of cytotoxic T lymphocyte (CTL) responses by nef-dependent induction of Fas ligand (CD95L) expression on simian immunodeficiency virus-infected cells
-
Xu X.N., Screaton G.R., Gotch F.M., Dong T., Tan R., Almond N., Walker B., Stebbings R., Kent K., Nagata S., et al. Evasion of cytotoxic T lymphocyte (CTL) responses by nef-dependent induction of Fas ligand (CD95L) expression on simian immunodeficiency virus-infected cells. J. Exp. Med. 186 (1997) 7-16
-
(1997)
J. Exp. Med.
, vol.186
, pp. 7-16
-
-
Xu, X.N.1
Screaton, G.R.2
Gotch, F.M.3
Dong, T.4
Tan, R.5
Almond, N.6
Walker, B.7
Stebbings, R.8
Kent, K.9
Nagata, S.10
|