메뉴 건너뛰기




Volumn 79, Issue 17, 2005, Pages 11422-11433

Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8αβ

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; AMINO ACID; CD28 ANTIGEN; CD4 ANTIGEN; CD8ALPHA ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NEF PROTEIN;

EID: 23844471509     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.79.17.11422-11433.2005     Document Type: Article
Times cited : (68)

References (69)
  • 1
    • 0028180868 scopus 로고
    • Nef induces CD4 endocytosis: Requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain
    • Aiken, C., J. Konner, N. R. Landau, M. E. Lenburg, and D. Trono. 1994. Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain. Cell 76:853-864.
    • (1994) Cell , vol.76 , pp. 853-864
    • Aiken, C.1    Konner, J.2    Landau, N.R.3    Lenburg, M.E.4    Trono, D.5
  • 2
    • 0031872106 scopus 로고    scopus 로고
    • Regions of human immunodeficiency virus type 1 nef required for function in vivo
    • Aldrovandi, G. M., L. Gao, G. Bristol, and J. A. Zack. 1998. Regions of human immunodeficiency virus type 1 nef required for function in vivo. J. Virol. 72:7032-7039.
    • (1998) J. Virol. , vol.72 , pp. 7032-7039
    • Aldrovandi, G.M.1    Gao, L.2    Bristol, G.3    Zack, J.A.4
  • 5
    • 0033625405 scopus 로고    scopus 로고
    • Role of CD8beta domains in CD8 coreceptor function: Importance for MHC I binding, signaling, and positive selection of CD8+ T cells in the thymus
    • Bosselut, R., S. Kubo, T. Guinter, J. L. Kopacz, J. D. Altman, L. Feigenbaum, and A. Singer. 2000. Role of CD8beta domains in CD8 coreceptor function: importance for MHC I binding, signaling, and positive selection of CD8+ T cells in the thymus. Immunity 12:409-418.
    • (2000) Immunity , vol.12 , pp. 409-418
    • Bosselut, R.1    Kubo, S.2    Guinter, T.3    Kopacz, J.L.4    Altman, J.D.5    Feigenbaum, L.6    Singer, A.7
  • 6
    • 0024415579 scopus 로고
    • Comparison of phosphorylation and internalization of the antigen receptor/CD3 complex, CD8, and class I MHC-encoded proteins on T cells. Role of intracytoplasmic domains analyzed with hybrid CD8/class I molecules
    • Boyer, C., N. Auphan, J. Gabert, D. Blanc, B. Malissen, and A. M. Schmitt-Verhulst. 1989. Comparison of phosphorylation and internalization of the antigen receptor/CD3 complex, CD8, and class I MHC-encoded proteins on T cells. Role of intracytoplasmic domains analyzed with hybrid CD8/class I molecules. J. Immunol. 143:1905-1914.
    • (1989) J. Immunol. , vol.143 , pp. 1905-1914
    • Boyer, C.1    Auphan, N.2    Gabert, J.3    Blanc, D.4    Malissen, B.5    Schmitt-Verhulst, A.M.6
  • 8
    • 0032488027 scopus 로고    scopus 로고
    • A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor
    • Bresnahan, P. A., W. Yonemoto, S. Ferrell, D. Williams Herman, R. Geleziunas, and W. C. Greene. 1998. A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor. Curr. Biol. 8:1235-1238.
    • (1998) Curr. Biol. , vol.8 , pp. 1235-1238
    • Bresnahan, P.A.1    Yonemoto, W.2    Ferrell, S.3    Williams Herman, D.4    Geleziunas, R.5    Greene, W.C.6
  • 9
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp, T. R., R. Bernards, and R. Agami. 2002. A system for stable expression of short interfering RNAs in mammalian cells. Science 296:550-553.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 10
    • 0027232778 scopus 로고
    • Endocytosis of beta 2 integrins by stimulated human neutrophils analyzed by flow cytometry
    • Chambers, J. D., S. I. Simon, E. M. Berger, L. A. Sklar, and K. E. Arfors. 1993. Endocytosis of beta 2 integrins by stimulated human neutrophils analyzed by flow cytometry. J. Leukoc. Biol. 53:462-469.
    • (1993) J. Leukoc. Biol. , vol.53 , pp. 462-469
    • Chambers, J.D.1    Simon, S.I.2    Berger, E.M.3    Sklar, L.A.4    Arfors, K.E.5
  • 11
    • 0032415170 scopus 로고    scopus 로고
    • Construction of single-chain antibodies that bind an overlapping epitope of HIV-1 Nef
    • Chang, A. H., J. A. Hoxie, S. Cassol, M. O'Shaughnessy, and F. Jirik. 1998. Construction of single-chain antibodies that bind an overlapping epitope of HIV-1 Nef. FEBS Lett. 441:307-312.
    • (1998) FEBS Lett. , vol.441 , pp. 307-312
    • Chang, A.H.1    Hoxie, J.A.2    Cassol, S.3    O'Shaughnessy, M.4    Jirik, F.5
  • 12
    • 4444351647 scopus 로고    scopus 로고
    • High levels of human immunodeficiency virus infection of CD8 lymphocytes expressing CD4 in vivo
    • Cochrane, A., S. Imlach, C. Leen, G. Scott, D. Kennedy, and P. Simmonds. 2004. High levels of human immunodeficiency virus infection of CD8 lymphocytes expressing CD4 in vivo. J. Virol. 78:9862-9871.
    • (2004) J. Virol. , vol.78 , pp. 9862-9871
    • Cochrane, A.1    Imlach, S.2    Leen, C.3    Scott, G.4    Kennedy, D.5    Simmonds, P.6
  • 13
    • 0032530773 scopus 로고    scopus 로고
    • Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity
    • Craig, H. M., M. W. Pandori, and J. C. Guatelli. 1998. Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity. Proc. Natl. Acad. Sci. USA 95:11229-11234.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 11229-11234
    • Craig, H.M.1    Pandori, M.W.2    Guatelli, J.C.3
  • 15
    • 0025893166 scopus 로고
    • Generation of anti-human CD8 beta-specific antibodies using transfectants expressing mixed-species CD8 heterodimers
    • DiSanto, J. P., L. A. Terry, and N. Flomenberg. 1991. Generation of anti-human CD8 beta-specific antibodies using transfectants expressing mixed-species CD8 heterodimers. J. Immunol. Methods. 141:123-131.
    • (1991) J. Immunol. Methods , vol.141 , pp. 123-131
    • Disanto, J.P.1    Terry, L.A.2    Flomenberg, N.3
  • 16
    • 0034330458 scopus 로고    scopus 로고
    • Two independent regions of HIV-1 Nef are required for connection with the endocytic pathway through binding to the mu 1 chain of AP1 complex
    • Erdtmann, L., K. Janvier, G. Raposo, H. M. Craig, P. Benaroch, C. Berlioz-Torrent, J. C. Guatelli, R. Benarous, and S. Benichou. 2000. Two independent regions of HIV-1 Nef are required for connection with the endocytic pathway through binding to the mu 1 chain of AP1 complex. Traffic 1:871-883.
    • (2000) Traffic , vol.1 , pp. 871-883
    • Erdtmann, L.1    Janvier, K.2    Raposo, G.3    Craig, H.M.4    Benaroch, P.5    Berlioz-Torrent, C.6    Guatelli, J.C.7    Benarous, R.8    Benichou, S.9
  • 17
    • 0036230879 scopus 로고    scopus 로고
    • Live and let die: Nef functions beyond HIV replication
    • Fackler, O. T., and A. S. Baur. 2002. Live and let die: Nef functions beyond HIV replication. Immunity 16:493-497.
    • (2002) Immunity , vol.16 , pp. 493-497
    • Fackler, O.T.1    Baur, A.S.2
  • 18
    • 0032539865 scopus 로고    scopus 로고
    • Activation of CD8+ T lymphocytes through the T-cell receptor turns on CD4 gene expression: Implications for HIV pathogenesis
    • Flamand, L., R. W. Crowley, P. Lusso, S. Colombini Hatch, D. M. Margolis, and R. C. Gallo. 1998. Activation of CD8+ T lymphocytes through the T-cell receptor turns on CD4 gene expression: implications for HIV pathogenesis. Proc. Natl. Acad. Sci. USA 95:3111-3116.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 3111-3116
    • Flamand, L.1    Crowley, R.W.2    Lusso, P.3    Colombini Hatch, S.4    Margolis, D.M.5    Gallo, R.C.6
  • 19
    • 2342663130 scopus 로고    scopus 로고
    • The CD8 isoform CD8alphaalpha is not a functional homologue of the TCR coreceptor CD8alphabeta
    • Gangadharan, D., and H. Cheroutre. 2004. The CD8 isoform CD8alphaalpha is not a functional homologue of the TCR coreceptor CD8alphabeta. Curr. Opin. Immunol. 16:264-270.
    • (2004) Curr. Opin. Immunol. , vol.16 , pp. 264-270
    • Gangadharan, D.1    Cheroutre, H.2
  • 20
    • 0027450321 scopus 로고
    • The negative effect of human immunodeficiency virus type 1 Nef on cell surface CD4 expression is not species specific and requires the cytoplasmic domain of CD4
    • Garcia, J. V., J. Alfano, and A. D. Miller. 1993. The negative effect of human immunodeficiency virus type 1 Nef on cell surface CD4 expression is not species specific and requires the cytoplasmic domain of CD4. J. Virol. 67:1511-1516.
    • (1993) J. Virol. , vol.67 , pp. 1511-1516
    • Garcia, J.V.1    Alfano, J.2    Miller, A.D.3
  • 21
    • 0025733252 scopus 로고
    • Serine phosphorylation-independent downregulation of cell-surface CD4 by nef
    • Garcia, J. V., and A. D. Miller. 1991. Serine phosphorylation-independent downregulation of cell-surface CD4 by nef. Nature 350:508-511.
    • (1991) Nature , vol.350 , pp. 508-511
    • Garcia, J.V.1    Miller, A.D.2
  • 22
    • 0035985203 scopus 로고    scopus 로고
    • Subunit H of the V-ATPase involved in endocytosis shows homology to beta-adaptins
    • Geyer, M., O. T. Fackler, and B. M. Peterlin. 2002. Subunit H of the V-ATPase involved in endocytosis shows homology to beta-adaptins. Mol. Biol. Cell 13:2045-2056.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 2045-2056
    • Geyer, M.1    Fackler, O.T.2    Peterlin, B.M.3
  • 23
    • 0037047282 scopus 로고    scopus 로고
    • Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machinery
    • Geyer, M., H. Yu, R. Mandic, T. Linnemann, Y. H. Zheng, O. T. Fackler, and B. M. Peterlin. 2002. Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machinery. J. Biol. Chem. 277:28521-28529.
    • (2002) J. Biol. Chem. , vol.277 , pp. 28521-28529
    • Geyer, M.1    Yu, H.2    Mandic, R.3    Linnemann, T.4    Zheng, Y.H.5    Fackler, O.T.6    Peterlin, B.M.7
  • 24
    • 0030990038 scopus 로고    scopus 로고
    • CD8 lineage commitment in the absence of CD8
    • Goldrath, A. W., K. A. Hogquist, and M. J. Bevan. 1997. CD8 lineage commitment in the absence of CD8. Immunity 6:633-642.
    • (1997) Immunity , vol.6 , pp. 633-642
    • Goldrath, A.W.1    Hogquist, K.A.2    Bevan, M.J.3
  • 25
    • 0032488055 scopus 로고    scopus 로고
    • A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4
    • Greenberg, M., L. DeTulleo, I. Rapoport, J. Skowronski, and T. Kirchhausen. 1998. A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4. Curr. Biol. 8:1239-1242.
    • (1998) Curr. Biol. , vol.8 , pp. 1239-1242
    • Greenberg, M.1    Detulleo, L.2    Rapoport, I.3    Skowronski, J.4    Kirchhausen, T.5
  • 26
    • 0030684068 scopus 로고    scopus 로고
    • Colocalization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation
    • Greenberg, M. E., S. Bronson, M. Lock, M. Neumann, G. N. Pavlakis, and J. Skowronski. 1997. Colocalization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation. EMBO J. 16:6964-6976.
    • (1997) EMBO J. , vol.16 , pp. 6964-6976
    • Greenberg, M.E.1    Bronson, S.2    Lock, M.3    Neumann, M.4    Pavlakis, G.N.5    Skowronski, J.6
  • 27
    • 0029795040 scopus 로고    scopus 로고
    • The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR
    • Grzesiek, S., S. J. Stahl, P. T. Wingfield, and A. Bax. 1996. The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR. Biochemistry 35:10256-10261.
    • (1996) Biochemistry , vol.35 , pp. 10256-10261
    • Grzesiek, S.1    Stahl, S.J.2    Wingfield, P.T.3    Bax, A.4
  • 28
    • 0025150549 scopus 로고
    • Alternative splice acceptor utilization during human immunodeficiency virus type 1 infection of cultured cells
    • Guatelli, J. C., T. R. Gingeras, and D. D. Richman. 1990. Alternative splice acceptor utilization during human immunodeficiency virus type 1 infection of cultured cells. J. Virol. 64:4093-4098.
    • (1990) J. Virol. , vol.64 , pp. 4093-4098
    • Guatelli, J.C.1    Gingeras, T.R.2    Richman, D.D.3
  • 29
    • 0028128822 scopus 로고
    • Myristoylation-dependent binding of HIV-1 Nef to CD4
    • Harris, M. P., and J. C. Neil. 1994. Myristoylation-dependent binding of HIV-1 Nef to CD4. J. Mol. Biol. 241:136-142.
    • (1994) J. Mol. Biol. , vol.241 , pp. 136-142
    • Harris, M.P.1    Neil, J.C.2
  • 30
    • 0035169887 scopus 로고    scopus 로고
    • Activated peripheral CD8 lymphocytes express CD4 in vivo and are targets for infection by human immunodeficiency virus type 1
    • Imlach, S., S. McBreen, T. Shirafuji, C. Leen, J. E. Bell, and P. Simmonds. 2001. Activated peripheral CD8 lymphocytes express CD4 in vivo and are targets for infection by human immunodeficiency virus type 1. J. Virol. 75:11555-11564.
    • (2001) J. Virol. , vol.75 , pp. 11555-11564
    • Imlach, S.1    McBreen, S.2    Shirafuji, T.3    Leen, C.4    Bell, J.E.5    Simmonds, P.6
  • 31
    • 0028986357 scopus 로고
    • CD8 beta chain influences CD8 alpha chain-associated Lck kinase activity
    • Irie, H. Y., K. S. Ravichandran, and S. J. Burakoff. 1995. CD8 beta chain influences CD8 alpha chain-associated Lck kinase activity. J. Exp. Med. 181:1267-1273.
    • (1995) J. Exp. Med. , vol.181 , pp. 1267-1273
    • Irie, H.Y.1    Ravichandran, K.S.2    Burakoff, S.J.3
  • 32
    • 0028467792 scopus 로고
    • A role for the cytoplasmic tail of the beta chain of CD8 in thymic selection
    • Itano, A., D. Cado, F. K. Chan, and E. Robey. 1994. A role for the cytoplasmic tail of the beta chain of CD8 in thymic selection. Immunity 1:287-290.
    • (1994) Immunity , vol.1 , pp. 287-290
    • Itano, A.1    Cado, D.2    Chan, F.K.3    Robey, E.4
  • 34
    • 0030296456 scopus 로고    scopus 로고
    • Decreased alpha/beta heterodimer among CD8 molecules of peripheral blood T cells in Wiskott-Aldrich syndrome
    • Kawabata, K., M. Nagasawa, T. Morio, H. Okawa, and J. Yata. 1996. Decreased alpha/beta heterodimer among CD8 molecules of peripheral blood T cells in Wiskott-Aldrich syndrome. Clin. Immunol. Immunopathol. 81:129-135.
    • (1996) Clin. Immunol. Immunopathol. , vol.81 , pp. 129-135
    • Kawabata, K.1    Nagasawa, M.2    Morio, T.3    Okawa, H.4    Yata, J.5
  • 35
    • 0033280324 scopus 로고    scopus 로고
    • Adaptors for clathrin-mediated traffic
    • Kirchhausen, T. 1999. Adaptors for clathrin-mediated traffic. Annu. Rev. Cell Dev. Biol. 15:705-732.
    • (1999) Annu. Rev. Cell Dev. Biol. , vol.15 , pp. 705-732
    • Kirchhausen, T.1
  • 36
    • 0031660975 scopus 로고    scopus 로고
    • + lymphocytes induces CD4 expression and allows human immunodeficiency virus type 1 infection
    • + lymphocytes induces CD4 expression and allows human immunodeficiency virus type 1 infection. J. Virol. 72:9054-9060.
    • (1998) J. Virol. , vol.72 , pp. 9054-9060
    • Kitchen, S.G.1    Korin, Y.D.2    Roth, M.D.3    Landay, A.4    Zack, J.A.5
  • 37
    • 0033798906 scopus 로고    scopus 로고
    • Distinct trafficking pathways mediate Nef-induced and clathrin-dependent major histocompatibility complex class I down-regulation
    • Le Gall, S., F. Buseyne, A. Trocha, B. D. Walker, J. M. Heard, and O. Schwartz. 2000. Distinct trafficking pathways mediate Nef-induced and clathrin-dependent major histocompatibility complex class I down-regulation. J. Virol. 74:9256-9266.
    • (2000) J. Virol. , vol.74 , pp. 9256-9266
    • Le Gall, S.1    Buseyne, F.2    Trocha, A.3    Walker, B.D.4    Heard, J.M.5    Schwartz, O.6
  • 39
    • 2442489212 scopus 로고    scopus 로고
    • Frequent infection of peripheral blood CD8-positive T-lymphocytes with HIV-1
    • Edinburgh Heterosexual Transmission Study Group
    • Livingstone, W. J., M. Moore, D. Innes, J. E. Bell, and P. Simmonds. 1996. Frequent infection of peripheral blood CD8-positive T-lymphocytes with HIV-1. Edinburgh Heterosexual Transmission Study Group. Lancet 348:649-654.
    • (1996) Lancet , vol.348 , pp. 649-654
    • Livingstone, W.J.1    Moore, M.2    Innes, D.3    Bell, J.E.4    Simmonds, P.5
  • 40
    • 0035121469 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Nef-induced CD4 cell surface downregulation is inhibited by ikarugamycin
    • Luo, T., B. L. Fredericksen, K. Hasumi, A. Endo, and J. V. Garcia. 2001. Human immunodeficiency virus type 1 Nef-induced CD4 cell surface downregulation is inhibited by ikarugamycin. J. Virol. 75:2488-2492.
    • (2001) J. Virol. , vol.75 , pp. 2488-2492
    • Luo, T.1    Fredericksen, B.L.2    Hasumi, K.3    Endo, A.4    Garcia, J.V.5
  • 41
    • 0030614819 scopus 로고    scopus 로고
    • The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane
    • Mangasarian, A., M. Foti, C. Aiken, D. Chin, J. L. Carpentier, and D. Trono. 1997. The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane. Immunity 6:67-77.
    • (1997) Immunity , vol.6 , pp. 67-77
    • Mangasarian, A.1    Foti, M.2    Aiken, C.3    Chin, D.4    Carpentier, J.L.5    Trono, D.6
  • 42
    • 0033013962 scopus 로고    scopus 로고
    • Nef-induced CD4 and major histocompatibility complex class I (MHC-1) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-1 trafficking
    • Mangasarian, A., V. Piguet, J. K. Wang, Y. L. Chen, and D. Trono. 1999. Nef-induced CD4 and major histocompatibility complex class I (MHC-1) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-1 trafficking. J. Virol. 73:1964-1973.
    • (1999) J. Virol. , vol.73 , pp. 1964-1973
    • Mangasarian, A.1    Piguet, V.2    Wang, J.K.3    Chen, Y.L.4    Trono, D.5
  • 43
    • 0027179109 scopus 로고
    • Endocytic regulation of the T lymphocyte coreceptor proteins CD4 and CD8
    • Marsh, M., I. J. Parsons, P. Reid, and A. Pelchen-Matthews. 1993. Endocytic regulation of the T lymphocyte coreceptor proteins CD4 and CD8. Biochem. Soc. Trans. 21:703-706.
    • (1993) Biochem. Soc. Trans. , vol.21 , pp. 703-706
    • Marsh, M.1    Parsons, I.J.2    Reid, P.3    Pelchen-Matthews, A.4
  • 45
    • 0034044314 scopus 로고    scopus 로고
    • The PSIPRED protein structure prediction server
    • McGuffin, L. J., K. Bryson, and D. T. Jones. 2000. The PSIPRED protein structure prediction server. Bioinformatics 16:404-405.
    • (2000) Bioinformatics , vol.16 , pp. 404-405
    • McGuffin, L.J.1    Bryson, K.2    Jones, D.T.3
  • 46
    • 0035912222 scopus 로고    scopus 로고
    • Cellular immune responses to HIV
    • McMichael, A. J., and S. L. Rowland-Jones. 2001. Cellular immune responses to HIV. Nature 410:980-987.
    • (2001) Nature , vol.410 , pp. 980-987
    • McMichael, A.J.1    Rowland-Jones, S.L.2
  • 47
  • 48
    • 0024114857 scopus 로고
    • A second subunit of CD8 is expressed in human T cells
    • Norment, A. M., and D. R. Littman. 1988. A second subunit of CD8 is expressed in human T cells. EMBO J. 7:3433-3439.
    • (1988) EMBO J. , vol.7 , pp. 3433-3439
    • Norment, A.M.1    Littman, D.R.2
  • 49
    • 0026032662 scopus 로고
    • Differential endocytosis of CD4 in lymphocytic and nonlymphocytic cells
    • Pelchen-Matthews, A., J. E. Armes, G. Griffiths, and M. Marsh. 1991. Differential endocytosis of CD4 in lymphocytic and nonlymphocytic cells. J. Exp. Med. 173:575-587.
    • (1991) J. Exp. Med. , vol.173 , pp. 575-587
    • Pelchen-Matthews, A.1    Armes, J.E.2    Griffiths, G.3    Marsh, M.4
  • 50
    • 0032079665 scopus 로고    scopus 로고
    • Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes
    • Piguet, V., Y. L. Chen, A. Mangasarian, M. Foti, J. L. Carpentier, and D. Trono. 1998. Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes. EMBO J. 17:2472-2481.
    • (1998) EMBO J. , vol.17 , pp. 2472-2481
    • Piguet, V.1    Chen, Y.L.2    Mangasarian, A.3    Foti, M.4    Carpentier, J.L.5    Trono, D.6
  • 51
    • 0033515427 scopus 로고    scopus 로고
    • Nef-induced CD4 degradation: A diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes
    • Piguet, V., F. Gu, M. Foti, N. Demaurex, J. Gruenberg, J. L. Carpentier, and D. Trono. 1999. Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes. Cell 97:63-73.
    • (1999) Cell , vol.97 , pp. 63-73
    • Piguet, V.1    Gu, F.2    Foti, M.3    Demaurex, N.4    Gruenberg, J.5    Carpentier, J.L.6    Trono, D.7
  • 52
    • 0035088131 scopus 로고    scopus 로고
    • Direct in vitro binding of full-length human immunodeficiency virus type 1 Nef protein to CD4 cytoplasmic domain
    • Preusser, A., L. Briese, A. S. Baur, and D. Willbold. 2001. Direct in vitro binding of full-length human immunodeficiency virus type 1 Nef protein to CD4 cytoplasmic domain. J. Virol. 75:3960-3964.
    • (2001) J. Virol. , vol.75 , pp. 3960-3964
    • Preusser, A.1    Briese, L.2    Baur, A.S.3    Willbold, D.4
  • 53
    • 0036079735 scopus 로고    scopus 로고
    • Presence of a helix in human CD4 cytoplasmic domain promotes binding to HIV-1 Nef protein
    • Preusser, A., L. Briese, and D. Willbold. 2002. Presence of a helix in human CD4 cytoplasmic domain promotes binding to HIV-1 Nef protein. Biochem. Biophys. Res. Commun. 292:734-740.
    • (2002) Biochem. Biophys. Res. Commun. , vol.292 , pp. 734-740
    • Preusser, A.1    Briese, L.2    Willbold, D.3
  • 54
    • 0025281329 scopus 로고
    • Structure and expression of tat-, rev-, and nef-specific transcripts of human immunodeficiency virus type 1 in infected lymphocytes and macrophages
    • Robert-Guroff, M., M. Popovic, S. Gartner, P. Markham, R. C. Gallo, and M. S. Reitz. 1990. Structure and expression of tat-, rev-, and nef-specific transcripts of human immunodeficiency virus type 1 in infected lymphocytes and macrophages. J. Virol. 64:3391-3398.
    • (1990) J. Virol. , vol.64 , pp. 3391-3398
    • Robert-Guroff, M.1    Popovic, M.2    Gartner, S.3    Markham, P.4    Gallo, R.C.5    Reitz, M.S.6
  • 55
    • 14844322164 scopus 로고    scopus 로고
    • CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms
    • Rose, J. J., K. Janvier, S. Chandrasekhar, R. P. Sekaly, J. S. Bonifacino, and S. Venkatesan. 2005. CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms. J. Biol. Chem. 280:7413-7426.
    • (2005) J. Biol. Chem. , vol.280 , pp. 7413-7426
    • Rose, J.J.1    Janvier, K.2    Chandrasekhar, S.3    Sekaly, R.P.4    Bonifacino, J.S.5    Venkatesan, S.6
  • 56
    • 0029989195 scopus 로고    scopus 로고
    • Nef-CD4 physical interaction sensed with the yeast two-hybrid system
    • Rossi, F., A. Gallina, and G. Milanesi. 1996. Nef-CD4 physical interaction sensed with the yeast two-hybrid system. Virology 217:397-403.
    • (1996) Virology , vol.217 , pp. 397-403
    • Rossi, F.1    Gallina, A.2    Milanesi, G.3
  • 57
    • 0141521574 scopus 로고    scopus 로고
    • Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles
    • Schindler, M., S. Wurfl, P. Benaroch, T. C. Greenough, R. Daniels, P. Easterbrook, M. Brenner, J. Munch, and F. Kirchhoff. 2003. Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles. J. Virol. 77:10548-10556.
    • (2003) J. Virol. , vol.77 , pp. 10548-10556
    • Schindler, M.1    Wurfl, S.2    Benaroch, P.3    Greenough, T.C.4    Daniels, R.5    Easterbrook, P.6    Brenner, M.7    Munch, J.8    Kirchhoff, F.9
  • 58
    • 0032105515 scopus 로고    scopus 로고
    • Expression of the CD8alpha beta-heterodimer on CD8(+) T lymphocytes in peripheral blood lymphocytes of human immunodeficiency virus- and human immunodeficiency virus+ individuals
    • Schmitz, J. E., M. A. Forman, M. A. Lifton, O. Concepcion, K. A. Reimann, Jr., C. S. Crumpacker, J. F. Daley, R. S. Gelman, and N. L. Letvin. 1998. Expression of the CD8alpha beta-heterodimer on CD8(+) T lymphocytes in peripheral blood lymphocytes of human immunodeficiency virus- and human immunodeficiency virus+ individuals. Blood 92:198-206.
    • (1998) Blood , vol.92 , pp. 198-206
    • Schmitz, J.E.1    Forman, M.A.2    Lifton, M.A.3    Concepcion, O.4    Reimann Jr., K.A.5    Crumpacker, C.S.6    Daley, J.F.7    Gelman, R.S.8    Letvin, N.L.9
  • 59
    • 0029875421 scopus 로고    scopus 로고
    • Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein
    • Schwartz, O., V. Marechal, S. Le Gall, F. Lemonnier, and J. M. Heard. 1996. Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein. Nat. Med. 2:338-342.
    • (1996) Nat. Med. , vol.2 , pp. 338-342
    • Schwartz, O.1    Marechal, V.2    Le Gall, S.3    Lemonnier, F.4    Heard, J.M.5
  • 60
    • 0031659902 scopus 로고    scopus 로고
    • HIV load in highly purified CD8+ T cells retrieved from pulmonary and blood compartments
    • Semenzato, G., C. Agostini, L. Chieco-Bianchi, and A. De Rossi. 1998. HIV load in highly purified CD8+ T cells retrieved from pulmonary and blood compartments. J. Leukoc. Biol. 64:298-301.
    • (1998) J. Leukoc. Biol. , vol.64 , pp. 298-301
    • Semenzato, G.1    Agostini, C.2    Chieco-Bianchi, L.3    De Rossi, A.4
  • 61
    • 0141993006 scopus 로고    scopus 로고
    • Signaling but not trafficking function of HIV-1 protein Nef is essential for Nef-induced defects in human intrathymic T-cell development
    • Stove, V., E. Naessens, C. Stove, T. Swigut, J. Plum, and B. Verhasselt. 2003. Signaling but not trafficking function of HIV-1 protein Nef is essential for Nef-induced defects in human intrathymic T-cell development. Blood 102:2925-2932.
    • (2003) Blood , vol.102 , pp. 2925-2932
    • Stove, V.1    Naessens, E.2    Stove, C.3    Swigut, T.4    Plum, J.5    Verhasselt, B.6
  • 63
    • 0035794535 scopus 로고    scopus 로고
    • Mechanism for down-regulation of CD28 by Nef
    • Swigut, T., N. Shohdy, and J. Skowronski. 2001. Mechanism for down-regulation of CD28 by Nef. EMBO J. 20:1593-1604.
    • (2001) EMBO J. , vol.20 , pp. 1593-1604
    • Swigut, T.1    Shohdy, N.2    Skowronski, J.3
  • 64
    • 0025332456 scopus 로고
    • Differential expression and regulation of the human CD8 alpha and CD8 beta chains
    • Terry, L. A., J. P. DiSanto, T. N. Small, and N. Flomenberg. 1990. Differential expression and regulation of the human CD8 alpha and CD8 beta chains. Tissue Antigens 35:82-91.
    • (1990) Tissue Antigens , vol.35 , pp. 82-91
    • Terry, L.A.1    Disanto, J.P.2    Small, T.N.3    Flomenberg, N.4
  • 66
    • 0031962626 scopus 로고    scopus 로고
    • Retrovirally transduced CD34++ human cord blood cells generate T cells expressing high levels of the retroviral encoded green fluorescent protein marker in vitro
    • Verhasselt, B., M. De Smedt, R. Verhelst, E. Naessens, and J. Plum. 1998. Retrovirally transduced CD34++ human cord blood cells generate T cells expressing high levels of the retroviral encoded green fluorescent protein marker in vitro. Blood 91:431-440.
    • (1998) Blood , vol.91 , pp. 431-440
    • Verhasselt, B.1    De Smedt, M.2    Verhelst, R.3    Naessens, E.4    Plum, J.5
  • 67
    • 0032855131 scopus 로고    scopus 로고
    • Human immunodeficiency virus nef gene expression affects generation and function of human T cells, but not dendritic cells
    • Verhasselt, B., E. Naessens, C. Verhofstede, M. De Smedt, S. Schollen, T. Kerre, D. Vanhecke, and J. Plum. 1999. Human immunodeficiency virus nef gene expression affects generation and function of human T cells, but not dendritic cells. Blood 94:2809-2818.
    • (1999) Blood , vol.94 , pp. 2809-2818
    • Verhasselt, B.1    Naessens, E.2    Verhofstede, C.3    De Smedt, M.4    Schollen, S.5    Kerre, T.6    Vanhecke, D.7    Plum, J.8
  • 68
    • 0028468552 scopus 로고
    • The CD8 coreceptor revisited: One chain good, two chains better
    • Zamoyska, R. 1994. The CD8 coreceptor revisited: one chain good, two chains better. Immunity 1:243-246.
    • (1994) Immunity , vol.1 , pp. 243-246
    • Zamoyska, R.1
  • 69
    • 0032978712 scopus 로고    scopus 로고
    • Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors
    • Zufferey, R., J. E. Donello, D. Trono, and T. J. Hope. 1999. Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J. Virol. 73:2886-2892.
    • (1999) J. Virol. , vol.73 , pp. 2886-2892
    • Zufferey, R.1    Donello, J.E.2    Trono, D.3    Hope, T.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.