-
1
-
-
0028180868
-
Nef induces CD4 endocytosis: Requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain
-
Aiken, C., J. Konner, N. R. Landau, M. E. Lenburg, and D. Trono. 1994. Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain. Cell 76:853-864.
-
(1994)
Cell
, vol.76
, pp. 853-864
-
-
Aiken, C.1
Konner, J.2
Landau, N.R.3
Lenburg, M.E.4
Trono, D.5
-
2
-
-
0031872106
-
Regions of human immunodeficiency virus type 1 nef required for function in vivo
-
Aldrovandi, G. M., L. Gao, G. Bristol, and J. A. Zack. 1998. Regions of human immunodeficiency virus type 1 nef required for function in vivo. J. Virol. 72:7032-7039.
-
(1998)
J. Virol.
, vol.72
, pp. 7032-7039
-
-
Aldrovandi, G.M.1
Gao, L.2
Bristol, G.3
Zack, J.A.4
-
3
-
-
0035914485
-
CD8beta endows CD8 with efficient coreceptor function by coupling T-cell receptor/CD3 to raft-associated CD8/p56(lck) complexes
-
Arcaro, A., C. Gregoire, T. R. Bakker, L. Baldi, M. Jordan, L. Goffin, N. Boucheron, F. Wurm, P. A. van der Merwe, B. Malissen, and I. F. Luescher. 2001. CD8beta endows CD8 with efficient coreceptor function by coupling T-cell receptor/CD3 to raft-associated CD8/p56(lck) complexes. J. Exp. Med. 194:1485-1495.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 1485-1495
-
-
Arcaro, A.1
Gregoire, C.2
Bakker, T.R.3
Baldi, L.4
Jordan, M.5
Goffin, L.6
Boucheron, N.7
Wurm, F.8
Van Der Merwe, P.A.9
Malissen, B.10
Luescher, I.F.11
-
4
-
-
0034664043
-
Essential role of CD8 palmitoylation in CD8 coreceptor function
-
Arcaro, A., C. Gregoire, N. Boucheron, S. Stolz, E. Palmer, B. Malissen, and I. F. Luescher. 2000. Essential role of CD8 palmitoylation in CD8 coreceptor function. J. Immunol. 165:2068-2076.
-
(2000)
J. Immunol.
, vol.165
, pp. 2068-2076
-
-
Arcaro, A.1
Gregoire, C.2
Boucheron, N.3
Stolz, S.4
Palmer, E.5
Malissen, B.6
Luescher, I.F.7
-
5
-
-
0033625405
-
Role of CD8beta domains in CD8 coreceptor function: Importance for MHC I binding, signaling, and positive selection of CD8+ T cells in the thymus
-
Bosselut, R., S. Kubo, T. Guinter, J. L. Kopacz, J. D. Altman, L. Feigenbaum, and A. Singer. 2000. Role of CD8beta domains in CD8 coreceptor function: importance for MHC I binding, signaling, and positive selection of CD8+ T cells in the thymus. Immunity 12:409-418.
-
(2000)
Immunity
, vol.12
, pp. 409-418
-
-
Bosselut, R.1
Kubo, S.2
Guinter, T.3
Kopacz, J.L.4
Altman, J.D.5
Feigenbaum, L.6
Singer, A.7
-
6
-
-
0024415579
-
Comparison of phosphorylation and internalization of the antigen receptor/CD3 complex, CD8, and class I MHC-encoded proteins on T cells. Role of intracytoplasmic domains analyzed with hybrid CD8/class I molecules
-
Boyer, C., N. Auphan, J. Gabert, D. Blanc, B. Malissen, and A. M. Schmitt-Verhulst. 1989. Comparison of phosphorylation and internalization of the antigen receptor/CD3 complex, CD8, and class I MHC-encoded proteins on T cells. Role of intracytoplasmic domains analyzed with hybrid CD8/class I molecules. J. Immunol. 143:1905-1914.
-
(1989)
J. Immunol.
, vol.143
, pp. 1905-1914
-
-
Boyer, C.1
Auphan, N.2
Gabert, J.3
Blanc, D.4
Malissen, B.5
Schmitt-Verhulst, A.M.6
-
7
-
-
9144261631
-
T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: Implications for HIV pathogenesis
-
Brenchley, J. M., B. J. Hill, D. R. Ambrozak, D. A. Price, F. J. Guenaga, J. P. Casazza, J. Kuruppu, J. Yazdani, S. A. Migueles, M. Connors, M. Roederer, D. C. Douek, and R. A. Koup. 2004. T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: implications for HIV pathogenesis. J. Virol. 78:1160-1168.
-
(2004)
J. Virol.
, vol.78
, pp. 1160-1168
-
-
Brenchley, J.M.1
Hill, B.J.2
Ambrozak, D.R.3
Price, D.A.4
Guenaga, F.J.5
Casazza, J.P.6
Kuruppu, J.7
Yazdani, J.8
Migueles, S.A.9
Connors, M.10
Roederer, M.11
Douek, D.C.12
Koup, R.A.13
-
8
-
-
0032488027
-
A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor
-
Bresnahan, P. A., W. Yonemoto, S. Ferrell, D. Williams Herman, R. Geleziunas, and W. C. Greene. 1998. A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor. Curr. Biol. 8:1235-1238.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1235-1238
-
-
Bresnahan, P.A.1
Yonemoto, W.2
Ferrell, S.3
Williams Herman, D.4
Geleziunas, R.5
Greene, W.C.6
-
9
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp, T. R., R. Bernards, and R. Agami. 2002. A system for stable expression of short interfering RNAs in mammalian cells. Science 296:550-553.
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
10
-
-
0027232778
-
Endocytosis of beta 2 integrins by stimulated human neutrophils analyzed by flow cytometry
-
Chambers, J. D., S. I. Simon, E. M. Berger, L. A. Sklar, and K. E. Arfors. 1993. Endocytosis of beta 2 integrins by stimulated human neutrophils analyzed by flow cytometry. J. Leukoc. Biol. 53:462-469.
-
(1993)
J. Leukoc. Biol.
, vol.53
, pp. 462-469
-
-
Chambers, J.D.1
Simon, S.I.2
Berger, E.M.3
Sklar, L.A.4
Arfors, K.E.5
-
11
-
-
0032415170
-
Construction of single-chain antibodies that bind an overlapping epitope of HIV-1 Nef
-
Chang, A. H., J. A. Hoxie, S. Cassol, M. O'Shaughnessy, and F. Jirik. 1998. Construction of single-chain antibodies that bind an overlapping epitope of HIV-1 Nef. FEBS Lett. 441:307-312.
-
(1998)
FEBS Lett.
, vol.441
, pp. 307-312
-
-
Chang, A.H.1
Hoxie, J.A.2
Cassol, S.3
O'Shaughnessy, M.4
Jirik, F.5
-
12
-
-
4444351647
-
High levels of human immunodeficiency virus infection of CD8 lymphocytes expressing CD4 in vivo
-
Cochrane, A., S. Imlach, C. Leen, G. Scott, D. Kennedy, and P. Simmonds. 2004. High levels of human immunodeficiency virus infection of CD8 lymphocytes expressing CD4 in vivo. J. Virol. 78:9862-9871.
-
(2004)
J. Virol.
, vol.78
, pp. 9862-9871
-
-
Cochrane, A.1
Imlach, S.2
Leen, C.3
Scott, G.4
Kennedy, D.5
Simmonds, P.6
-
13
-
-
0032530773
-
Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity
-
Craig, H. M., M. W. Pandori, and J. C. Guatelli. 1998. Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity. Proc. Natl. Acad. Sci. USA 95:11229-11234.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 11229-11234
-
-
Craig, H.M.1
Pandori, M.W.2
Guatelli, J.C.3
-
14
-
-
0024987981
-
In vitro studies of HIV-1 infection in thymic lymphocytes: A putative role of the thymus in AIDS pathogenesis
-
De Rossi, A., M. L. Calabro, M. Panozzo, D. Bernardi, B. Caruso, G. Tridente, and L. ChiecoBianchi. 1990. In vitro studies of HIV-1 infection in thymic lymphocytes: a putative role of the thymus in AIDS pathogenesis. AIDS Res. Hum. Retroviruses 6:287-298.
-
(1990)
AIDS Res. Hum. Retroviruses
, vol.6
, pp. 287-298
-
-
De Rossi, A.1
Calabro, M.L.2
Panozzo, M.3
Bernardi, D.4
Caruso, B.5
Tridente, G.6
Chiecobianchi, L.7
-
15
-
-
0025893166
-
Generation of anti-human CD8 beta-specific antibodies using transfectants expressing mixed-species CD8 heterodimers
-
DiSanto, J. P., L. A. Terry, and N. Flomenberg. 1991. Generation of anti-human CD8 beta-specific antibodies using transfectants expressing mixed-species CD8 heterodimers. J. Immunol. Methods. 141:123-131.
-
(1991)
J. Immunol. Methods
, vol.141
, pp. 123-131
-
-
Disanto, J.P.1
Terry, L.A.2
Flomenberg, N.3
-
16
-
-
0034330458
-
Two independent regions of HIV-1 Nef are required for connection with the endocytic pathway through binding to the mu 1 chain of AP1 complex
-
Erdtmann, L., K. Janvier, G. Raposo, H. M. Craig, P. Benaroch, C. Berlioz-Torrent, J. C. Guatelli, R. Benarous, and S. Benichou. 2000. Two independent regions of HIV-1 Nef are required for connection with the endocytic pathway through binding to the mu 1 chain of AP1 complex. Traffic 1:871-883.
-
(2000)
Traffic
, vol.1
, pp. 871-883
-
-
Erdtmann, L.1
Janvier, K.2
Raposo, G.3
Craig, H.M.4
Benaroch, P.5
Berlioz-Torrent, C.6
Guatelli, J.C.7
Benarous, R.8
Benichou, S.9
-
17
-
-
0036230879
-
Live and let die: Nef functions beyond HIV replication
-
Fackler, O. T., and A. S. Baur. 2002. Live and let die: Nef functions beyond HIV replication. Immunity 16:493-497.
-
(2002)
Immunity
, vol.16
, pp. 493-497
-
-
Fackler, O.T.1
Baur, A.S.2
-
18
-
-
0032539865
-
Activation of CD8+ T lymphocytes through the T-cell receptor turns on CD4 gene expression: Implications for HIV pathogenesis
-
Flamand, L., R. W. Crowley, P. Lusso, S. Colombini Hatch, D. M. Margolis, and R. C. Gallo. 1998. Activation of CD8+ T lymphocytes through the T-cell receptor turns on CD4 gene expression: implications for HIV pathogenesis. Proc. Natl. Acad. Sci. USA 95:3111-3116.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 3111-3116
-
-
Flamand, L.1
Crowley, R.W.2
Lusso, P.3
Colombini Hatch, S.4
Margolis, D.M.5
Gallo, R.C.6
-
19
-
-
2342663130
-
The CD8 isoform CD8alphaalpha is not a functional homologue of the TCR coreceptor CD8alphabeta
-
Gangadharan, D., and H. Cheroutre. 2004. The CD8 isoform CD8alphaalpha is not a functional homologue of the TCR coreceptor CD8alphabeta. Curr. Opin. Immunol. 16:264-270.
-
(2004)
Curr. Opin. Immunol.
, vol.16
, pp. 264-270
-
-
Gangadharan, D.1
Cheroutre, H.2
-
20
-
-
0027450321
-
The negative effect of human immunodeficiency virus type 1 Nef on cell surface CD4 expression is not species specific and requires the cytoplasmic domain of CD4
-
Garcia, J. V., J. Alfano, and A. D. Miller. 1993. The negative effect of human immunodeficiency virus type 1 Nef on cell surface CD4 expression is not species specific and requires the cytoplasmic domain of CD4. J. Virol. 67:1511-1516.
-
(1993)
J. Virol.
, vol.67
, pp. 1511-1516
-
-
Garcia, J.V.1
Alfano, J.2
Miller, A.D.3
-
21
-
-
0025733252
-
Serine phosphorylation-independent downregulation of cell-surface CD4 by nef
-
Garcia, J. V., and A. D. Miller. 1991. Serine phosphorylation-independent downregulation of cell-surface CD4 by nef. Nature 350:508-511.
-
(1991)
Nature
, vol.350
, pp. 508-511
-
-
Garcia, J.V.1
Miller, A.D.2
-
22
-
-
0035985203
-
Subunit H of the V-ATPase involved in endocytosis shows homology to beta-adaptins
-
Geyer, M., O. T. Fackler, and B. M. Peterlin. 2002. Subunit H of the V-ATPase involved in endocytosis shows homology to beta-adaptins. Mol. Biol. Cell 13:2045-2056.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 2045-2056
-
-
Geyer, M.1
Fackler, O.T.2
Peterlin, B.M.3
-
23
-
-
0037047282
-
Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machinery
-
Geyer, M., H. Yu, R. Mandic, T. Linnemann, Y. H. Zheng, O. T. Fackler, and B. M. Peterlin. 2002. Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machinery. J. Biol. Chem. 277:28521-28529.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 28521-28529
-
-
Geyer, M.1
Yu, H.2
Mandic, R.3
Linnemann, T.4
Zheng, Y.H.5
Fackler, O.T.6
Peterlin, B.M.7
-
24
-
-
0030990038
-
CD8 lineage commitment in the absence of CD8
-
Goldrath, A. W., K. A. Hogquist, and M. J. Bevan. 1997. CD8 lineage commitment in the absence of CD8. Immunity 6:633-642.
-
(1997)
Immunity
, vol.6
, pp. 633-642
-
-
Goldrath, A.W.1
Hogquist, K.A.2
Bevan, M.J.3
-
25
-
-
0032488055
-
A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4
-
Greenberg, M., L. DeTulleo, I. Rapoport, J. Skowronski, and T. Kirchhausen. 1998. A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4. Curr. Biol. 8:1239-1242.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1239-1242
-
-
Greenberg, M.1
Detulleo, L.2
Rapoport, I.3
Skowronski, J.4
Kirchhausen, T.5
-
26
-
-
0030684068
-
Colocalization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation
-
Greenberg, M. E., S. Bronson, M. Lock, M. Neumann, G. N. Pavlakis, and J. Skowronski. 1997. Colocalization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation. EMBO J. 16:6964-6976.
-
(1997)
EMBO J.
, vol.16
, pp. 6964-6976
-
-
Greenberg, M.E.1
Bronson, S.2
Lock, M.3
Neumann, M.4
Pavlakis, G.N.5
Skowronski, J.6
-
27
-
-
0029795040
-
The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR
-
Grzesiek, S., S. J. Stahl, P. T. Wingfield, and A. Bax. 1996. The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR. Biochemistry 35:10256-10261.
-
(1996)
Biochemistry
, vol.35
, pp. 10256-10261
-
-
Grzesiek, S.1
Stahl, S.J.2
Wingfield, P.T.3
Bax, A.4
-
28
-
-
0025150549
-
Alternative splice acceptor utilization during human immunodeficiency virus type 1 infection of cultured cells
-
Guatelli, J. C., T. R. Gingeras, and D. D. Richman. 1990. Alternative splice acceptor utilization during human immunodeficiency virus type 1 infection of cultured cells. J. Virol. 64:4093-4098.
-
(1990)
J. Virol.
, vol.64
, pp. 4093-4098
-
-
Guatelli, J.C.1
Gingeras, T.R.2
Richman, D.D.3
-
29
-
-
0028128822
-
Myristoylation-dependent binding of HIV-1 Nef to CD4
-
Harris, M. P., and J. C. Neil. 1994. Myristoylation-dependent binding of HIV-1 Nef to CD4. J. Mol. Biol. 241:136-142.
-
(1994)
J. Mol. Biol.
, vol.241
, pp. 136-142
-
-
Harris, M.P.1
Neil, J.C.2
-
30
-
-
0035169887
-
Activated peripheral CD8 lymphocytes express CD4 in vivo and are targets for infection by human immunodeficiency virus type 1
-
Imlach, S., S. McBreen, T. Shirafuji, C. Leen, J. E. Bell, and P. Simmonds. 2001. Activated peripheral CD8 lymphocytes express CD4 in vivo and are targets for infection by human immunodeficiency virus type 1. J. Virol. 75:11555-11564.
-
(2001)
J. Virol.
, vol.75
, pp. 11555-11564
-
-
Imlach, S.1
McBreen, S.2
Shirafuji, T.3
Leen, C.4
Bell, J.E.5
Simmonds, P.6
-
31
-
-
0028986357
-
CD8 beta chain influences CD8 alpha chain-associated Lck kinase activity
-
Irie, H. Y., K. S. Ravichandran, and S. J. Burakoff. 1995. CD8 beta chain influences CD8 alpha chain-associated Lck kinase activity. J. Exp. Med. 181:1267-1273.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 1267-1273
-
-
Irie, H.Y.1
Ravichandran, K.S.2
Burakoff, S.J.3
-
32
-
-
0028467792
-
A role for the cytoplasmic tail of the beta chain of CD8 in thymic selection
-
Itano, A., D. Cado, F. K. Chan, and E. Robey. 1994. A role for the cytoplasmic tail of the beta chain of CD8 in thymic selection. Immunity 1:287-290.
-
(1994)
Immunity
, vol.1
, pp. 287-290
-
-
Itano, A.1
Cado, D.2
Chan, F.K.3
Robey, E.4
-
33
-
-
0037424537
-
HIV-1 Nef stabilizes the association of adaptor protein complexes with membranes
-
Janvier, K., H. Craig, D. Hitchin, R. Madrid, N. Sol-Foulon, L. Renault, J. Cherfils, D. Cassel, S. Benichou, and J. Guatelli. 2003. HIV-1 Nef stabilizes the association of adaptor protein complexes with membranes. J. Biol. Chem. 278:8725-8732.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8725-8732
-
-
Janvier, K.1
Craig, H.2
Hitchin, D.3
Madrid, R.4
Sol-Foulon, N.5
Renault, L.6
Cherfils, J.7
Cassel, D.8
Benichou, S.9
Guatelli, J.10
-
34
-
-
0030296456
-
Decreased alpha/beta heterodimer among CD8 molecules of peripheral blood T cells in Wiskott-Aldrich syndrome
-
Kawabata, K., M. Nagasawa, T. Morio, H. Okawa, and J. Yata. 1996. Decreased alpha/beta heterodimer among CD8 molecules of peripheral blood T cells in Wiskott-Aldrich syndrome. Clin. Immunol. Immunopathol. 81:129-135.
-
(1996)
Clin. Immunol. Immunopathol.
, vol.81
, pp. 129-135
-
-
Kawabata, K.1
Nagasawa, M.2
Morio, T.3
Okawa, H.4
Yata, J.5
-
35
-
-
0033280324
-
Adaptors for clathrin-mediated traffic
-
Kirchhausen, T. 1999. Adaptors for clathrin-mediated traffic. Annu. Rev. Cell Dev. Biol. 15:705-732.
-
(1999)
Annu. Rev. Cell Dev. Biol.
, vol.15
, pp. 705-732
-
-
Kirchhausen, T.1
-
37
-
-
0033798906
-
Distinct trafficking pathways mediate Nef-induced and clathrin-dependent major histocompatibility complex class I down-regulation
-
Le Gall, S., F. Buseyne, A. Trocha, B. D. Walker, J. M. Heard, and O. Schwartz. 2000. Distinct trafficking pathways mediate Nef-induced and clathrin-dependent major histocompatibility complex class I down-regulation. J. Virol. 74:9256-9266.
-
(2000)
J. Virol.
, vol.74
, pp. 9256-9266
-
-
Le Gall, S.1
Buseyne, F.2
Trocha, A.3
Walker, B.D.4
Heard, J.M.5
Schwartz, O.6
-
38
-
-
0035976604
-
T-cell responses modulated through interaction between CD8alphaalpha and the nonclassical MHC class I molecule, TL
-
Leishman, A. J., O. V. Naidenko, A. Attinger, F. Koning, C. J. Lena, Y. Xiong, H. C. Chang, E. Reinherz, M. Kronenberg, and H. Cheroutre. 2001. T-cell responses modulated through interaction between CD8alphaalpha and the nonclassical MHC class I molecule, TL. Science 294:1936-1939.
-
(2001)
Science
, vol.294
, pp. 1936-1939
-
-
Leishman, A.J.1
Naidenko, O.V.2
Attinger, A.3
Koning, F.4
Lena, C.J.5
Xiong, Y.6
Chang, H.C.7
Reinherz, E.8
Kronenberg, M.9
Cheroutre, H.10
-
39
-
-
2442489212
-
Frequent infection of peripheral blood CD8-positive T-lymphocytes with HIV-1
-
Edinburgh Heterosexual Transmission Study Group
-
Livingstone, W. J., M. Moore, D. Innes, J. E. Bell, and P. Simmonds. 1996. Frequent infection of peripheral blood CD8-positive T-lymphocytes with HIV-1. Edinburgh Heterosexual Transmission Study Group. Lancet 348:649-654.
-
(1996)
Lancet
, vol.348
, pp. 649-654
-
-
Livingstone, W.J.1
Moore, M.2
Innes, D.3
Bell, J.E.4
Simmonds, P.5
-
40
-
-
0035121469
-
Human immunodeficiency virus type 1 Nef-induced CD4 cell surface downregulation is inhibited by ikarugamycin
-
Luo, T., B. L. Fredericksen, K. Hasumi, A. Endo, and J. V. Garcia. 2001. Human immunodeficiency virus type 1 Nef-induced CD4 cell surface downregulation is inhibited by ikarugamycin. J. Virol. 75:2488-2492.
-
(2001)
J. Virol.
, vol.75
, pp. 2488-2492
-
-
Luo, T.1
Fredericksen, B.L.2
Hasumi, K.3
Endo, A.4
Garcia, J.V.5
-
41
-
-
0030614819
-
The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane
-
Mangasarian, A., M. Foti, C. Aiken, D. Chin, J. L. Carpentier, and D. Trono. 1997. The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane. Immunity 6:67-77.
-
(1997)
Immunity
, vol.6
, pp. 67-77
-
-
Mangasarian, A.1
Foti, M.2
Aiken, C.3
Chin, D.4
Carpentier, J.L.5
Trono, D.6
-
42
-
-
0033013962
-
Nef-induced CD4 and major histocompatibility complex class I (MHC-1) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-1 trafficking
-
Mangasarian, A., V. Piguet, J. K. Wang, Y. L. Chen, and D. Trono. 1999. Nef-induced CD4 and major histocompatibility complex class I (MHC-1) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-1 trafficking. J. Virol. 73:1964-1973.
-
(1999)
J. Virol.
, vol.73
, pp. 1964-1973
-
-
Mangasarian, A.1
Piguet, V.2
Wang, J.K.3
Chen, Y.L.4
Trono, D.5
-
43
-
-
0027179109
-
Endocytic regulation of the T lymphocyte coreceptor proteins CD4 and CD8
-
Marsh, M., I. J. Parsons, P. Reid, and A. Pelchen-Matthews. 1993. Endocytic regulation of the T lymphocyte coreceptor proteins CD4 and CD8. Biochem. Soc. Trans. 21:703-706.
-
(1993)
Biochem. Soc. Trans.
, vol.21
, pp. 703-706
-
-
Marsh, M.1
Parsons, I.J.2
Reid, P.3
Pelchen-Matthews, A.4
-
45
-
-
0034044314
-
The PSIPRED protein structure prediction server
-
McGuffin, L. J., K. Bryson, and D. T. Jones. 2000. The PSIPRED protein structure prediction server. Bioinformatics 16:404-405.
-
(2000)
Bioinformatics
, vol.16
, pp. 404-405
-
-
McGuffin, L.J.1
Bryson, K.2
Jones, D.T.3
-
46
-
-
0035912222
-
Cellular immune responses to HIV
-
McMichael, A. J., and S. L. Rowland-Jones. 2001. Cellular immune responses to HIV. Nature 410:980-987.
-
(2001)
Nature
, vol.410
, pp. 980-987
-
-
McMichael, A.J.1
Rowland-Jones, S.L.2
-
47
-
-
0042232673
-
Clathrin-mediated endocytosis in AP-2-depleted cells
-
Motley, A., N. A. Bright, M. N. Seaman, and M. S. Robinson. 2003. Clathrin-mediated endocytosis in AP-2-depleted cells. J. Cell Biol. 162:909-918.
-
(2003)
J. Cell Biol.
, vol.162
, pp. 909-918
-
-
Motley, A.1
Bright, N.A.2
Seaman, M.N.3
Robinson, M.S.4
-
48
-
-
0024114857
-
A second subunit of CD8 is expressed in human T cells
-
Norment, A. M., and D. R. Littman. 1988. A second subunit of CD8 is expressed in human T cells. EMBO J. 7:3433-3439.
-
(1988)
EMBO J.
, vol.7
, pp. 3433-3439
-
-
Norment, A.M.1
Littman, D.R.2
-
49
-
-
0026032662
-
Differential endocytosis of CD4 in lymphocytic and nonlymphocytic cells
-
Pelchen-Matthews, A., J. E. Armes, G. Griffiths, and M. Marsh. 1991. Differential endocytosis of CD4 in lymphocytic and nonlymphocytic cells. J. Exp. Med. 173:575-587.
-
(1991)
J. Exp. Med.
, vol.173
, pp. 575-587
-
-
Pelchen-Matthews, A.1
Armes, J.E.2
Griffiths, G.3
Marsh, M.4
-
50
-
-
0032079665
-
Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes
-
Piguet, V., Y. L. Chen, A. Mangasarian, M. Foti, J. L. Carpentier, and D. Trono. 1998. Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes. EMBO J. 17:2472-2481.
-
(1998)
EMBO J.
, vol.17
, pp. 2472-2481
-
-
Piguet, V.1
Chen, Y.L.2
Mangasarian, A.3
Foti, M.4
Carpentier, J.L.5
Trono, D.6
-
51
-
-
0033515427
-
Nef-induced CD4 degradation: A diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes
-
Piguet, V., F. Gu, M. Foti, N. Demaurex, J. Gruenberg, J. L. Carpentier, and D. Trono. 1999. Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes. Cell 97:63-73.
-
(1999)
Cell
, vol.97
, pp. 63-73
-
-
Piguet, V.1
Gu, F.2
Foti, M.3
Demaurex, N.4
Gruenberg, J.5
Carpentier, J.L.6
Trono, D.7
-
52
-
-
0035088131
-
Direct in vitro binding of full-length human immunodeficiency virus type 1 Nef protein to CD4 cytoplasmic domain
-
Preusser, A., L. Briese, A. S. Baur, and D. Willbold. 2001. Direct in vitro binding of full-length human immunodeficiency virus type 1 Nef protein to CD4 cytoplasmic domain. J. Virol. 75:3960-3964.
-
(2001)
J. Virol.
, vol.75
, pp. 3960-3964
-
-
Preusser, A.1
Briese, L.2
Baur, A.S.3
Willbold, D.4
-
53
-
-
0036079735
-
Presence of a helix in human CD4 cytoplasmic domain promotes binding to HIV-1 Nef protein
-
Preusser, A., L. Briese, and D. Willbold. 2002. Presence of a helix in human CD4 cytoplasmic domain promotes binding to HIV-1 Nef protein. Biochem. Biophys. Res. Commun. 292:734-740.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.292
, pp. 734-740
-
-
Preusser, A.1
Briese, L.2
Willbold, D.3
-
54
-
-
0025281329
-
Structure and expression of tat-, rev-, and nef-specific transcripts of human immunodeficiency virus type 1 in infected lymphocytes and macrophages
-
Robert-Guroff, M., M. Popovic, S. Gartner, P. Markham, R. C. Gallo, and M. S. Reitz. 1990. Structure and expression of tat-, rev-, and nef-specific transcripts of human immunodeficiency virus type 1 in infected lymphocytes and macrophages. J. Virol. 64:3391-3398.
-
(1990)
J. Virol.
, vol.64
, pp. 3391-3398
-
-
Robert-Guroff, M.1
Popovic, M.2
Gartner, S.3
Markham, P.4
Gallo, R.C.5
Reitz, M.S.6
-
55
-
-
14844322164
-
CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms
-
Rose, J. J., K. Janvier, S. Chandrasekhar, R. P. Sekaly, J. S. Bonifacino, and S. Venkatesan. 2005. CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms. J. Biol. Chem. 280:7413-7426.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 7413-7426
-
-
Rose, J.J.1
Janvier, K.2
Chandrasekhar, S.3
Sekaly, R.P.4
Bonifacino, J.S.5
Venkatesan, S.6
-
56
-
-
0029989195
-
Nef-CD4 physical interaction sensed with the yeast two-hybrid system
-
Rossi, F., A. Gallina, and G. Milanesi. 1996. Nef-CD4 physical interaction sensed with the yeast two-hybrid system. Virology 217:397-403.
-
(1996)
Virology
, vol.217
, pp. 397-403
-
-
Rossi, F.1
Gallina, A.2
Milanesi, G.3
-
57
-
-
0141521574
-
Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles
-
Schindler, M., S. Wurfl, P. Benaroch, T. C. Greenough, R. Daniels, P. Easterbrook, M. Brenner, J. Munch, and F. Kirchhoff. 2003. Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles. J. Virol. 77:10548-10556.
-
(2003)
J. Virol.
, vol.77
, pp. 10548-10556
-
-
Schindler, M.1
Wurfl, S.2
Benaroch, P.3
Greenough, T.C.4
Daniels, R.5
Easterbrook, P.6
Brenner, M.7
Munch, J.8
Kirchhoff, F.9
-
58
-
-
0032105515
-
Expression of the CD8alpha beta-heterodimer on CD8(+) T lymphocytes in peripheral blood lymphocytes of human immunodeficiency virus- and human immunodeficiency virus+ individuals
-
Schmitz, J. E., M. A. Forman, M. A. Lifton, O. Concepcion, K. A. Reimann, Jr., C. S. Crumpacker, J. F. Daley, R. S. Gelman, and N. L. Letvin. 1998. Expression of the CD8alpha beta-heterodimer on CD8(+) T lymphocytes in peripheral blood lymphocytes of human immunodeficiency virus- and human immunodeficiency virus+ individuals. Blood 92:198-206.
-
(1998)
Blood
, vol.92
, pp. 198-206
-
-
Schmitz, J.E.1
Forman, M.A.2
Lifton, M.A.3
Concepcion, O.4
Reimann Jr., K.A.5
Crumpacker, C.S.6
Daley, J.F.7
Gelman, R.S.8
Letvin, N.L.9
-
59
-
-
0029875421
-
Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein
-
Schwartz, O., V. Marechal, S. Le Gall, F. Lemonnier, and J. M. Heard. 1996. Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein. Nat. Med. 2:338-342.
-
(1996)
Nat. Med.
, vol.2
, pp. 338-342
-
-
Schwartz, O.1
Marechal, V.2
Le Gall, S.3
Lemonnier, F.4
Heard, J.M.5
-
60
-
-
0031659902
-
HIV load in highly purified CD8+ T cells retrieved from pulmonary and blood compartments
-
Semenzato, G., C. Agostini, L. Chieco-Bianchi, and A. De Rossi. 1998. HIV load in highly purified CD8+ T cells retrieved from pulmonary and blood compartments. J. Leukoc. Biol. 64:298-301.
-
(1998)
J. Leukoc. Biol.
, vol.64
, pp. 298-301
-
-
Semenzato, G.1
Agostini, C.2
Chieco-Bianchi, L.3
De Rossi, A.4
-
61
-
-
0141993006
-
Signaling but not trafficking function of HIV-1 protein Nef is essential for Nef-induced defects in human intrathymic T-cell development
-
Stove, V., E. Naessens, C. Stove, T. Swigut, J. Plum, and B. Verhasselt. 2003. Signaling but not trafficking function of HIV-1 protein Nef is essential for Nef-induced defects in human intrathymic T-cell development. Blood 102:2925-2932.
-
(2003)
Blood
, vol.102
, pp. 2925-2932
-
-
Stove, V.1
Naessens, E.2
Stove, C.3
Swigut, T.4
Plum, J.5
Verhasselt, B.6
-
62
-
-
0035834141
-
HIV-1 Nef impairs MHC class II antigen presentation and surface expression
-
Stumptner-Cuvelette, P., S. Morchoisne, M. Dugast, S. Le Gall, G. Raposo, O. Schwartz, and P. Benaroch. 2001. HIV-1 Nef impairs MHC class II antigen presentation and surface expression. Proc. Natl. Acad. Sci. USA 98:12144-12149.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12144-12149
-
-
Stumptner-Cuvelette, P.1
Morchoisne, S.2
Dugast, M.3
Le Gall, S.4
Raposo, G.5
Schwartz, O.6
Benaroch, P.7
-
63
-
-
0035794535
-
Mechanism for down-regulation of CD28 by Nef
-
Swigut, T., N. Shohdy, and J. Skowronski. 2001. Mechanism for down-regulation of CD28 by Nef. EMBO J. 20:1593-1604.
-
(2001)
EMBO J.
, vol.20
, pp. 1593-1604
-
-
Swigut, T.1
Shohdy, N.2
Skowronski, J.3
-
64
-
-
0025332456
-
Differential expression and regulation of the human CD8 alpha and CD8 beta chains
-
Terry, L. A., J. P. DiSanto, T. N. Small, and N. Flomenberg. 1990. Differential expression and regulation of the human CD8 alpha and CD8 beta chains. Tissue Antigens 35:82-91.
-
(1990)
Tissue Antigens
, vol.35
, pp. 82-91
-
-
Terry, L.A.1
Disanto, J.P.2
Small, T.N.3
Flomenberg, N.4
-
65
-
-
3042841651
-
HIV/SIV escape from immune surveillance: Focus on Nef
-
Tolstrup, M., L. Ostergaard, A. L. Laursen, S. F. Pedersen, and M. Duch. 2004. HIV/SIV escape from immune surveillance: focus on Nef. Curr. HIV Res. 2:141-151.
-
(2004)
Curr. HIV Res.
, vol.2
, pp. 141-151
-
-
Tolstrup, M.1
Ostergaard, L.2
Laursen, A.L.3
Pedersen, S.F.4
Duch, M.5
-
66
-
-
0031962626
-
Retrovirally transduced CD34++ human cord blood cells generate T cells expressing high levels of the retroviral encoded green fluorescent protein marker in vitro
-
Verhasselt, B., M. De Smedt, R. Verhelst, E. Naessens, and J. Plum. 1998. Retrovirally transduced CD34++ human cord blood cells generate T cells expressing high levels of the retroviral encoded green fluorescent protein marker in vitro. Blood 91:431-440.
-
(1998)
Blood
, vol.91
, pp. 431-440
-
-
Verhasselt, B.1
De Smedt, M.2
Verhelst, R.3
Naessens, E.4
Plum, J.5
-
67
-
-
0032855131
-
Human immunodeficiency virus nef gene expression affects generation and function of human T cells, but not dendritic cells
-
Verhasselt, B., E. Naessens, C. Verhofstede, M. De Smedt, S. Schollen, T. Kerre, D. Vanhecke, and J. Plum. 1999. Human immunodeficiency virus nef gene expression affects generation and function of human T cells, but not dendritic cells. Blood 94:2809-2818.
-
(1999)
Blood
, vol.94
, pp. 2809-2818
-
-
Verhasselt, B.1
Naessens, E.2
Verhofstede, C.3
De Smedt, M.4
Schollen, S.5
Kerre, T.6
Vanhecke, D.7
Plum, J.8
-
68
-
-
0028468552
-
The CD8 coreceptor revisited: One chain good, two chains better
-
Zamoyska, R. 1994. The CD8 coreceptor revisited: one chain good, two chains better. Immunity 1:243-246.
-
(1994)
Immunity
, vol.1
, pp. 243-246
-
-
Zamoyska, R.1
-
69
-
-
0032978712
-
Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors
-
Zufferey, R., J. E. Donello, D. Trono, and T. J. Hope. 1999. Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J. Virol. 73:2886-2892.
-
(1999)
J. Virol.
, vol.73
, pp. 2886-2892
-
-
Zufferey, R.1
Donello, J.E.2
Trono, D.3
Hope, T.J.4
|