메뉴 건너뛰기




Volumn 8, Issue 4, 2011, Pages 604-614

Radiolabeled oligonucleotides for antisense imaging

Author keywords

Antisense imaging; Antisense therapy; Molecular imaging; Mrna; Pet; Radiopharmaceuticals; Spect

Indexed keywords


EID: 79960006189     PISSN: 15701794     EISSN: None     Source Type: Journal    
DOI: 10.2174/157017911796117241     Document Type: Review
Times cited : (24)

References (137)
  • 1
    • 0035043022 scopus 로고    scopus 로고
    • Targeting double stranded DNA with peptide nucleic acid(PNA)
    • Nielsen, P., Targeting double stranded DNA with peptide nucleic acid(PNA). Curr. Med. Chem., 2001, 8(5), 545-550.
    • (2001) Curr. Med. Chem , vol.8 , Issue.5 , pp. 545-550
    • Nielsen, P.1
  • 2
    • 0033548529 scopus 로고    scopus 로고
    • Anexperimental study of mechanism and specificity of peptide nucleic acid(PNA) binding to duplex DNA
    • Kuhn, H.; Demidov, V.; Nielsen, P.; Frank-Kamenetskii, M., Anexperimental study of mechanism and specificity of peptide nucleic acid(PNA) binding to duplex DNA. J. Mol. Biol., 1999, 286(5), 1337-1345.
    • (1999) J. Mol. Biol , vol.286 , Issue.5 , pp. 1337-1345
    • Kuhn, H.1    Demidov, V.2    Nielsen, P.3    Frank-Kamenetskii, M.4
  • 3
  • 4
    • 0033052318 scopus 로고    scopus 로고
    • Synthetic oligonucleotides: The development ofantisense therapeutics
    • Monteith, D.; Levin, A., Synthetic oligonucleotides: the development ofantisense therapeutics. Toxicol. Pathol., 1999, 27(1), 8-13.
    • (1999) Toxicol. Pathol , vol.27 , Issue.1 , pp. 8-13
    • Monteith, D.1    Levin, A.2
  • 5
    • 0036717382 scopus 로고    scopus 로고
    • Molecular imaging of cancer with positron emissiontomography
    • Gambhir, S., Molecular imaging of cancer with positron emissiontomography. Nat. Rev. Cancer, 2002, 2(9), 683-693.
    • (2002) Nat Rev. Cancer , vol.2 , Issue.9 , pp. 683-693
    • Gambhir, S.1
  • 6
    • 0034126959 scopus 로고    scopus 로고
    • PET: The merging of biology and imaging into molecular imaging
    • Phelps, M., PET: the merging of biology and imaging into molecular imaging. J. Nucl. Med., 2000, 41(4), 661-681.
    • (2000) J. Nucl. Med , vol.41 , Issue.4 , pp. 661-681
    • Phelps, M.1
  • 7
    • 84942750836 scopus 로고    scopus 로고
    • Emission tomography: The fundamentals of PETand SPECT
    • Academic Press
    • Wernick, M.; Aarsvold, J., Emission tomography: the fundamentals of PETand SPECT. Academic Press, 2004.
    • (2004)
    • Wernick, M.1    Aarsvold, J.2
  • 8
    • 67651083548 scopus 로고    scopus 로고
    • Multimodality Imaging: Beyond PET/CT and SPECT/CT
    • Cherry, S., Multimodality Imaging: Beyond PET/CT and SPECT/CT. Semin.Nucl. Med., 2009, 39, 348-353.
    • (2009) Semin.Nucl Med , vol.39 , pp. 348-353
    • Cherry, S.1
  • 9
    • 20644436492 scopus 로고    scopus 로고
    • Molecular imaging: A new approach to nuclear cardiology
    • Dobrucki, L.; Sinusas, A., Molecular imaging: a new approach to nuclear cardiology. Q. J. Nucl. Med. Mol. Imaging, 2005, 49(1), 106-115.
    • (2005) Q. J. Nucl. Med. Mol. Imaging , vol.49 , Issue.1 , pp. 106-115
    • Dobrucki, L.1    Sinusas, A.2
  • 11
    • 0035107945 scopus 로고    scopus 로고
    • Recent advances in imaging endogenous ortransferred gene expression utilizing radionuclide technologies in livingsubjects: Applications to breast cancer
    • Berger, F.; Gambhir, S., Recent advances in imaging endogenous ortransferred gene expression utilizing radionuclide technologies in livingsubjects: applications to breast cancer. Breast Cancer Res., 2001, 3(1), 28-35.
    • (2001) Breast Cancer Res , vol.3 , Issue.1 , pp. 28-35
    • Berger, F.1    Gambhir, S.2
  • 12
    • 31144461091 scopus 로고    scopus 로고
    • Instrumentation for molecular imaging in preclinical research: Micro-PET and Micro-SPECT
    • Chatziioannou, A., Instrumentation for molecular imaging in preclinical research: Micro-PET and Micro-SPECT. Proc. Am. Thorac. Soc., 2005, 2,533-536.
    • (2005) Proc. Am. Thorac. Soc , vol.2 , pp. 533-536
    • Chatziioannou, A.1
  • 13
    • 0032906375 scopus 로고    scopus 로고
    • Antisense and nuclear medicine
    • Hnatowich, D., Antisense and nuclear medicine. J. Nucl. Med., 1999, 40(4),693-703.
    • (1999) J. Nucl. Med , vol.40 , Issue.4 , pp. 693-703
    • Hnatowich, D.1
  • 14
    • 0033695063 scopus 로고    scopus 로고
    • Antisense imaging: Where are we now?
    • Hnatowich, D., Antisense imaging: Where are we now? Cancer Biother.Radiopharm., 2000, 15(5), 447-457.
    • (2000) Cancer Biother. Radiopharm , vol.15 , Issue.5 , pp. 447-457
    • Hnatowich, D.1
  • 15
    • 0033789658 scopus 로고    scopus 로고
    • In vivo antisense imaging
    • Tavitian, B., In vivo antisense imaging. Q. J. Nucl. Med., 2000, 44(3), 236-255.
    • (2000) Q. J. Nucl. Med , vol.44 , Issue.3 , pp. 236-255
    • Tavitian, B.1
  • 16
    • 0141885264 scopus 로고    scopus 로고
    • Antisense imaging: And miles to go before we sleep?
    • Lewis, M.; Jia, F., Antisense imaging: And miles to go before we sleep? J.Cell. Biochem., 2003, 90(3), 464-472.
    • (2003) J.Cell. Biochem , vol.90 , Issue.3 , pp. 464-472
    • Lewis, M.1    Jia, F.2
  • 17
    • 0026184805 scopus 로고
    • Development of sensitive radioiodinated anti-sense oligonucleotide probesby conjugation techniques
    • Dewanjee, M.; Ghafouripour, A.; Werner, R.; Serafini, A.; Sfakianakis, G., Development of sensitive radioiodinated anti-sense oligonucleotide probesby conjugation techniques. Bioconjug. Chem., 1991, 2(4), 195-200.
    • (1991) Bioconjug. Chem , vol.2 , Issue.4 , pp. 195-200
    • Dewanjee, M.1    Ghafouripour, A.2    Werner, R.3    Serafini, A.4    Sfakianakis, G.5
  • 19
    • 0003474640 scopus 로고
    • Hybridization in the analysis of RNA
    • IRL Press, Oxford
    • Williams, J.; Mason, P., Hybridization in the analysis of RNA. Nucleic acid hybridization. IRL Press, Oxford, 1985, 152-174.
    • (1985) Nucleic Acid Hybridization , pp. 152-174
    • Williams, J.1    Mason, P.2
  • 20
    • 49249137824 scopus 로고    scopus 로고
    • Anti-sense oligonucleotidelabeled with technetium-99m using hydrazinonictinamide derivative and Nhydroxysuccinimidyl S-acetylmercaptoacetyltriglycline: A comparison ofradiochemical behaviors and biological properties
    • Li, Y. C.; Tan, T. Z.; Zheng, J. G.; Zhang, C., Anti-sense oligonucleotidelabeled with technetium-99m using hydrazinonictinamide derivative and Nhydroxysuccinimidyl S-acetylmercaptoacetyltriglycline: a comparison ofradiochemical behaviors and biological properties. World J. Gastroenterol.,2008, 14(14), 2235-2240.
    • (2008) World J. Gastroenterol , vol.14 , Issue.14 , pp. 2235-2240
    • Li, Y.C.1    Tan, T.Z.2    Zheng, J.G.3    Zhang, C.4
  • 21
    • 0030935541 scopus 로고    scopus 로고
    • A generalmethod for labeling oligodeoxynucleotides with 18 F for in vivo PETimaging
    • Dolle, F.; Hinnen, F.; Vaufrey, F.; Tavitian, B.; Crouzel, C., A generalmethod for labeling oligodeoxynucleotides with 18 F for in vivo PETimaging. J. Labelled. Comp. Radiopharm., 1997, 39(4), 319-330.
    • (1997) J. Labelled. Comp. Radiopharm , vol.39 , Issue.4 , pp. 319-330
    • Dolle, F.1    Hinnen, F.2    Vaufrey, F.3    Tavitian, B.4    Crouzel, C.5
  • 24
    • 70350331801 scopus 로고    scopus 로고
    • Role of chelates in magnetic resonance imaging studies
    • Tripathi, L.; Kumar, P.; Singh, R., Role of chelates in magnetic resonance imaging studies. J. Cancer Res. Ther., 2009, 5(3), 148-153.
    • (2009) J. Cancer Res. Ther , vol.5 , Issue.3 , pp. 148-153
    • Tripathi, L.1    Kumar, P.2    Singh, R.3
  • 27
    • 0033754176 scopus 로고    scopus 로고
    • Influences ofthree chelators (HYNIC, MAG3 and DTPA) on the in vitro and in vivo behaviors of 99m Tc attached to antisense DNA
    • Zhang, Y.; Liu, N.; Zhu, Z.; Rusckowski, M.; Hnatowich, D., Influences ofthree chelators (HYNIC, MAG3 and DTPA) on the in vitro and in vivo behaviors of 99m Tc attached to antisense DNA. Eur. J. Nucl. Med., 2000,27, 1700-1707.
    • (2000) Eur. J. Nucl. Med , vol.27 , pp. 1700-1707
    • Zhang, Y.1    Liu, N.2    Zhu, Z.3    Rusckowski, M.4    Hnatowich, D.5
  • 28
    • 0031662031 scopus 로고    scopus 로고
    • 3-99mTc-labelingand biodistribution of a CAPL antisense oligodeoxynucleotide
    • Hjelstuen, O.; T-nnesen, H.; Bremer, P.; Verbruggen, A., 3 -99mTc-labelingand biodistribution of a CAPL antisense oligodeoxynucleotide. Nucl. Med.Biol., 1998, 25(7), 651-657.
    • (1998) Nucl. Med.Biol , vol.5 , Issue.7 , pp. 51-657
    • Hjelstuen, O.1    T-Nnesen, H.2    Bremer, P.3    Verbruggen, A.4
  • 29
    • 0032759371 scopus 로고    scopus 로고
    • Development of a lyophilized kit formulation for labeling of DNA probeswith 99mTc
    • Hjelstuen, O.; Saetern, A.; Tonnesen, H.; Bremer, P.; Verbruggen, A., Development of a lyophilized kit formulation for labeling of DNA probeswith 99mTc. Int. J. Pharm., 1999, 190(2), 197-205.
    • (1999) Int. J. Pharm , vol.190 , Issue.2 , pp. 197-205
    • Hjelstuen, O.1    Saetern, A.2    Tonnesen, H.3    Bremer, P.4    Verbruggen, A.5
  • 30
  • 31
    • 36849029717 scopus 로고    scopus 로고
    • Noninvasive imaging of human telomerase reverse transcriptase (hTERT)messenger RNA with 99mTc-radiolabeled antisense probes in malignanttumors
    • Liu, M.; Wang, R.; Zhang, C.; Yan, P.; Yu, M.; Di, L.; Liu, H.; Guo, F., Noninvasive imaging of human telomerase reverse transcriptase (hTERT)messenger RNA with 99mTc-radiolabeled antisense probes in malignanttumors. J. Nucl. Med., 2007, 48(12), 2028-2036.
    • (2007) J. Nucl. Med , vol.48 , Issue.12 , pp. 2028-2036
    • Liu, M.1    Wang, R.2    Zhang, C.3    Yan, P.4    Yu, M.5    Di, L.6    Liu, H.7    Guo, F.8
  • 32
    • 0036079203 scopus 로고    scopus 로고
    • Improving the Labeling of S-Acetyl NHS- MAG3-Conjugated MorpholinoOligomers
    • Liu, G.; Zhang, S.; He, J.; Zhu, Z.; Rusckowski, M.; Hnatowich, D., Improving the Labeling of S-Acetyl NHS- MAG3-Conjugated MorpholinoOligomers. Bioconjug. Chem., 2002, 13(4), 893-897.
    • (2002) Bioconjug. Chem , vol.13 , Issue.4 , pp. 893-897
    • Liu, G.1    Zhang, S.2    He, J.3    Zhu, Z.4    Rusckowski, M.5    Hnatowich, D.6
  • 33
  • 34
    • 34248562046 scopus 로고    scopus 로고
    • Methods for MAG3 conjugation and99mTc radiolabeling of biomolecules
    • Wang, Y.; Liu, G.; Hnatowich, D., Methods for MAG3 conjugation and99mTc radiolabeling of biomolecules. Nat. Protoc., 2006, 1, 1477-1480.
    • (2006) Nat. Protoc , vol.1 , pp. 1477-1480
    • Wang, Y.1    Liu, G.2    Hnatowich, D.3
  • 35
    • 0033019524 scopus 로고    scopus 로고
    • Imaging with radiolabeled antisenceoligonucleotides for the detection of intracellular messenger RNA andcardiovascular disease
    • Dewanjee, M.; Haider, N.; Narula, J., Imaging with radiolabeled antisenceoligonucleotides for the detection of intracellular messenger RNA andcardiovascular disease. J. Nucl. Cardiol., 1999, 6(3), 345-356.
    • (1999) J. Nucl. Cardiol , vol.6 , Issue.3 , pp. 345-356
    • Dewanjee, M.1    Haider, N.2    Narula, J.3
  • 36
    • 0028244690 scopus 로고
    • Noninvasive imaging of c-myconcogene messenger RNA with indium-111-antisense probes in a mammarytumor-bearing mouse model
    • Dewanjee, M.; Ghafouripour, A.; Kapadvanjwala, M.; Dewanjee, S.; Serafini, A.; Lopez, D.; Sfakianakis, G., Noninvasive imaging of c-myconcogene messenger RNA with indium-111-antisense probes in a mammarytumor-bearing mouse model. J. Nucl. Med., 1994, 35(6), 1054-1061.
    • (1994) J. Nucl. Med , vol.35 , Issue.6 , pp. 1054-1061
    • Dewanjee, M.1    Ghafouripour, A.2    Kapadvanjwala, M.3    Dewanjee, S.4    Serafini, A.5    Lopez, D.6    Sfakianakis, G.7
  • 37
    • 0036859952 scopus 로고    scopus 로고
    • Radiometal-Labeled Peptide- PNA Conjugates for Targetingbcl-2 Expression: Preparation, Characterization, and in Vitro mRNABinding
    • Lewis, M.; Jia, F.; Gallazzi, F.; Wang, Y.; Zhang, J.; Shenoy, N.; Lever, S.; Hannink, M., Radiometal-Labeled Peptide- PNA Conjugates for Targetingbcl-2 Expression: Preparation, Characterization, and in Vitro mRNABinding. Bioconjug. Chem., 2002, 13(6), 1176-1180.
    • (2002) Bioconjug. Chem , vol.13 , Issue.6 , pp. 1176-1180
    • Lewis, M.1    Jia, F.2    Gallazzi, F.3    Wang, Y.4    Zhang, J.5    Shenoy, N.6    Lever, S.7    Hannink, M.8
  • 38
    • 0032589007 scopus 로고    scopus 로고
    • A novel 111In-labeled antisense DNA probewith multi-chelating sites (MCS-probe) showing high specific radioactivityand labeling efficiency
    • Fujibayashi, Y.; Yoshimi, E.; Waki, A.; Sakahara, H.; Saga, T.; Konishi, J.; Yonekura, Y.; Yokoyama, A., A novel 111In-labeled antisense DNA probewith multi-chelating sites (MCS-probe) showing high specific radioactivityand labeling efficiency. Nucl. Med. Biol., 1999, 26(1), 17-21.
    • (1999) Nucl. Med. Biol , vol.26 , Issue.1 , pp. 17-21
    • Fujibayashi, Y.1    Yoshimi, E.2    Waki, A.3    Sakahara, H.4    Saga, T.5    Konishi, J.6    Yonekura, Y.7    Yokoyama, A.8
  • 41
    • 61849179561 scopus 로고    scopus 로고
    • In vivo SPECT and real-time gamma camera imaging of biodistribution andpharmacokinetics of siRNA delivery using an optimized radiolabeling andpurification procedure
    • Merkel, O.; Librizzi, D.; Pfestroff, A.; Schurrat, T.; Behe, M.; Kissel, T., In vivo SPECT and real-time gamma camera imaging of biodistribution andpharmacokinetics of siRNA delivery using an optimized radiolabeling andpurification procedure. Bioconjug. chem., 2009, 20, 174-182.
    • (2009) Bioconjug. Chem , vol.20 , pp. 174-182
    • Merkel, O.1    Librizzi, D.2    Pfestroff, A.3    Schurrat, T.4    Behe, M.5    Kissel, T.6
  • 43
    • 0033792956 scopus 로고    scopus 로고
    • Development ofDNA-based radiopharmaceuticals carrying Auger-electron emitters for antigene radiotherapy
    • Panyutin, I.; Winters, T.; Feinendegen, L.; Neumann, R., Development ofDNA-based radiopharmaceuticals carrying Auger-electron emitters for antigene radiotherapy. Q. J. Nucl. Med., 2000, 44(3), 256-267.
    • (2000) Q. J. Nucl. Med , vol.44 , Issue.3 , pp. 256-267
    • Panyutin, I.1    Winters, T.2    Feinendegen, L.3    Neumann, R.4
  • 44
    • 0028577812 scopus 로고
    • Sequence-specific DNA double-strand breaks induced by triplex froming 125I labeled oligonucleotides
    • Panyutin, I.; Neumann, R., Sequence-specific DNA double-strand breaks induced by triplex froming 125I labeled oligonucleotides. Nucleic acids res.,1994, 22(23), 4979-4982.
    • (1994) Nucleic Acids Res , vol.22 , Issue.23 , pp. 4979-4982
    • Panyutin, I.1    Neumann, R.2
  • 45
    • 0030839005 scopus 로고    scopus 로고
    • Synthesis and radioiodination ofa stannyl oligodeoxyribonucleotide
    • Dougan, H.; Hobbs, J.; Weitz, J.; Lyster, D., Synthesis and radioiodination ofa stannyl oligodeoxyribonucleotide. Nucleic acids res., 1997, 25(14), 2897-2901.
    • (1997) Nucleic Acids Res , vol.25 , Issue.14 , pp. 2897-2901
    • Dougan, H.1    Hobbs, J.2    Weitz, J.3    Lyster, D.4
  • 47
    • 0032474487 scopus 로고    scopus 로고
    • Rapid synthesis of a 5 -fluorinated oligodeoxy-nucleotide: Amodel antisense probe for use in imaging with positron emission tomography(PET)
    • Pan, D.; Gambhir, S.; Toyokuni, T.; Iyer, M.; Acharya, N.; Phelps, M.; Barrio, J., Rapid synthesis of a 5 -fluorinated oligodeoxy-nucleotide: Amodel antisense probe for use in imaging with positron emission tomography(PET). Bioorg. Med. Chem. Lett., 1998, 8(11), 1317-1320.
    • (1998) Bioorg. Med. Chem. Lett , vol.8 , Issue.11 , pp. 1317-1320
    • Pan, D.1    Gambhir, S.2    Toyokuni, T.3    Iyer, M.4    Acharya, N.5    Phelps, M.6    Barrio, J.7
  • 48
    • 0344461635 scopus 로고
    • Synthesis of carbon-11, fluorine-18, and nitrogen-13labeled radiotracers for biomedical applications
    • Brookhaven National Lab., Upton, NY(USA)
    • Fowler, J.; Wolf, A. Synthesis of carbon-11, fluorine-18, and nitrogen-13labeled radiotracers for biomedical applications. Nuclear Science Series: Nuclear Medicine; NAS-NS-3201, Brookhaven National Lab., Upton, NY(USA),1982.
    • (1982) Nuclear Science Series: Nuclear Medicine; NAS-NS-3201
    • Fowler, J.1    Wolf, A.2
  • 49
    • 0034042803 scopus 로고    scopus 로고
    • Fluorine-18 labeling of oligonucleotides bearing chemically-modified ribosephosphate backbones
    • Kuhnast, B.; Dolle, F.; Vaufrey, F.; Hinnen, F.; Crouzel, C.; Tavitian, B., Fluorine-18 labeling of oligonucleotides bearing chemically-modified ribosephosphate backbones. J. Labelled Comp. Radiopharm., 2000, 43(8), 837-848.
    • (2000) J. Labelled Comp. Radiopharm , vol.43 , Issue.8 , pp. 837-848
    • Kuhnast, B.1    Dolle, F.2    Vaufrey, F.3    Hinnen, F.4    Crouzel, C.5    Tavitian, B.6
  • 50
    • 3042530042 scopus 로고    scopus 로고
    • Synthesis and evaluation of a fluorine-18 labeled antisenseoligonucleotide as a potential PET tracer for iNOS mRNA expression
    • de Vries, E.; Vroegh, J.; Dijkstra, G.; Moshage, H.; Elsinga, P.; Jansen, P.; Vaalburg, W., Synthesis and evaluation of a fluorine-18 labeled antisenseoligonucleotide as a potential PET tracer for iNOS mRNA expression. Nucl.Med. Biol., 2004, 31(5), 605-612.
    • (2004) Nucl. Med. Biol , vol.31 , Issue.5 , pp. 605-612
    • de Vries, E.1    Vroegh, J.2    Dijkstra, G.3    Moshage, H.4    Elsinga, P.5    Jansen, P.6    Vaalburg, W.7
  • 51
    • 0001224559 scopus 로고    scopus 로고
    • 18 F-Labelling of oligonucleotides usingsuccinimido 4-[18F]-fluorobenzoate. Acta
    • Hedberg, E.; Langstrom, B., 18 F-Labelling of oligonucleotides usingsuccinimido 4-[18F]-fluorobenzoate. Acta Chem. Scand., 1998, 52(8), 1037-1039.
    • (1998) Chem. Scand , vol.52 , Issue.8 , pp. 1037-1039
    • Hedberg, E.1    Langstrom, B.2
  • 52
    • 0000314960 scopus 로고    scopus 로고
    • Synthesis of 4-([18 F]-Fluoromethyl)phenylisothiocyanate and its use in labelling oligonucleotides
    • Hedberg, E.; Langstrom, B., Synthesis of 4-([18 F]-Fluoromethyl)phenylisothiocyanate and its use in labelling oligonucleotides. Acta Chem. Scand.,1997, 51(12), 1236-1240.
    • (1997) Acta Chem. Scand , vol.51 , Issue.12 , pp. 1236-1240
    • Hedberg, E.1    Langstrom, B.2
  • 54
    • 0033615256 scopus 로고    scopus 로고
    • Visualization ofmRNA expression in CNS using 11C-labeled phosphorothioateoligodeoxynucleotide
    • Kobori, N.; Imahori, Y.; Mineura, K.; Ueda, S.; Fujii, R., Visualization ofmRNA expression in CNS using 11C-labeled phosphorothioateoligodeoxynucleotide. Neuroreport, 1999, 10(14), 2971-2974.
    • (1999) Neuroreport , vol.10 , Issue.14 , pp. 2971-2974
    • Kobori, N.1    Imahori, Y.2    Mineura, K.3    Ueda, S.4    Fujii, R.5
  • 55
    • 0007694872 scopus 로고
    • Development of Labelled Antisense Deoxyoligonucleotides (ODNs) for Usein PET. Synthesis of the [11C]-Labelled Dinucleotide [11C]-Thymidylyl (3'-5') Thymidine
    • Visser, G.; Vos, M.; Davenport, R.; Pike, V.; Medema, J.; Vaalburg, W.,Development of Labelled Antisense Deoxyoligonucleotides (ODNs) for Usein PET. Synthesis of the [11C]-Labelled Dinucleotide [11C]-Thymidylyl (3'-5') Thymidine. J. Labelled Comp. Radiopharm., 1995, 37, 341-343.
    • (1995) J. Labelled Comp. Radiopharm , vol.37 , pp. 341-343
    • Visser, G.1    Vos, M.2    Davenport, R.3    Pike, V.4    Medema, J.5    Vaalburg, W.6
  • 57
    • 14844343722 scopus 로고    scopus 로고
    • 68Ga-labeled peptides in tumorimaging
    • Maecke, H.; Hofmann, M.; Haberkorn, U., 68Ga-labeled peptides in tumorimaging. J. Nucl. Med. 2005, 46(1), 172S-178S.
    • (2005) J. Nucl. Med , vol.46 , Issue.1
    • Maecke, H.1    Hofmann, M.2    Haberkorn, U.3
  • 60
    • 44449140590 scopus 로고    scopus 로고
    • Biodistribution of 68Ga-Labeled LNA-DNA Mixmer Antisense Oligonucleotides for Rat Chromogranin-A
    • Lendvai, G.; Velikyan, I.; Estrada, S.; Eriksson, B.; Lângstr̂m B.; Bergstr̂m, M., Biodistribution of 68Ga-Labeled LNA-DNA Mixmer Antisense Oligonucleotides for Rat Chromogranin-A. Oligonucleotides,2008, 18(1), 33-49.
    • (2008) Oligonucleotides , vol.18 , Issue.1 , pp. 33-49
    • Lendvai, G.1    Velikyan, I.2    Estrada, S.3    Eriksson, B.4    Lângstr̂m, B.5    Bergstr̂m, M.6
  • 61
    • 0025433271 scopus 로고
    • Conjugates of oligonucleotides and modified oligonucleotides:A review of their synthesis and properties
    • Goodchild, J., Conjugates of oligonucleotides and modified oligonucleotides:a review of their synthesis and properties. Bioconjugate Chem., 1990, 1(3),165-187.
    • (1990) Bioconjugate Chem , vol.1 , Issue.3 , pp. 165-187
    • Goodchild, J.1
  • 62
    • 0027452716 scopus 로고
    • Chemical nucleic acid synthesis, modification and labelling
    • Sproat, B. S., Chemical nucleic acid synthesis, modification and labelling.Curr. Opin. Biotechnol., 1993, 4(1), 20-28.
    • (1993) Curr. Opin. Biotechnol , vol.4 , Issue.1 , pp. 20-28
    • Sproat, B.S.1
  • 63
    • 0029952811 scopus 로고    scopus 로고
    • In pursuit of antisense
    • Matteucci, M.; Wagner, R., In pursuit of antisense. Nature, 1996, 384,(6604), 20-22.
    • (1996) Nature , vol.384 , Issue.6604 , pp. 20-22
    • Matteucci, M.1    Wagner, R.2
  • 64
    • 0025743216 scopus 로고
    • Pharmacokinetics, biodistribution, andstability of oligonucleotide phorphorothidates in mice
    • Agarwal, S.; Temsamani, J.; Tang, J., Pharmacokinetics, biodistribution, andstability of oligonucleotide phorphorothidates in mice. Proc. Natl. Acad. Sci.USA, 1991, 88, 7595-7599.
    • (1991) Proc. Natl. Acad. Sci.USA , vol.88 , pp. 7595-7599
    • Agarwal, S.1    Temsamani, J.2    Tang, J.3
  • 65
  • 66
    • 0031936347 scopus 로고    scopus 로고
    • Impact of3'-exonuclease stereoselectivity on the kinetics of phosphorothioateoligonucleotide metabolism
    • Gilar, M.; Belenky, A.; Budman, Y.; Smisek, D. L.; Cohen, A. S., Impact of3'-exonuclease stereoselectivity on the kinetics of phosphorothioateoligonucleotide metabolism. Antisense Nucleic Acid Drug Dev., 1998, 8(1),35-42.
    • (1998) Antisense Nucleic Acid Drug Dev , vol.8 , Issue.1 , pp. 35-42
    • Gilar, M.1    Belenky, A.2    Budman, Y.3    Smisek, D.L.4    Cohen, A.S.5
  • 67
    • 0342436060 scopus 로고
    • Synthesis of phosphorothioatemethylphosphonate oligonucleotide co-polymers
    • Zhou, L.; Morocho, A.; Chen, B.; Cohen, J., Synthesis of phosphorothioatemethylphosphonate oligonucleotide co-polymers. Nucleic acids Res., 1994,22(3), 453-456.
    • (1994) Nucleic Acids Res , vol.22 , Issue.3 , pp. 453-456
    • Zhou, L.1    Morocho, A.2    Chen, B.3    Cohen, J.4
  • 68
    • 0025175236 scopus 로고
    • Disposition andmetabolism of oligodeoxynucleoside methylphosphonate following a singlei.v. injection in mice
    • Chen, T. L.; Miller, P. S.; Ts'o, P. O.; Colvin, O. M., Disposition andmetabolism of oligodeoxynucleoside methylphosphonate following a singlei.v. injection in mice. Drug. Metab. Dispos., 1990, 18(5), 815-818.
    • (1990) Drug. Metab. Dispos , vol.18 , Issue.5 , pp. 815-818
    • Chen, T.L.1    Miller, P.S.2    Ts'o, P.O.3    Colvin, O.M.4
  • 70
    • 0032833363 scopus 로고    scopus 로고
    • Evaluation of different types ofend-capping modifications on the stability of oligonucleotides toward 3'- and5'-exonucleases
    • Pandolfi, D.; Rauzi, F.; Capobianco, M. L., Evaluation of different types ofend-capping modifications on the stability of oligonucleotides toward 3'- and5'-exonucleases. Nucleosides Nucleotides, 1999, 18(9), 2051-2069.
    • (1999) Nucleosides Nucleotides , vol.18 , Issue.9 , pp. 2051-2069
    • Pandolfi, D.1    Rauzi, F.2    Capobianco, M.L.3
  • 73
    • 0030862707 scopus 로고    scopus 로고
    • Morpholino antisense oligomers: Design,preparation, and properties
    • Summerton, J., Weller, D., Morpholino antisense oligomers: design,preparation, and properties. Antisense Nucleic Acid Drug Dev., 1997, 7(3),187-195.
    • (1997) Antisense Nucleic Acid Drug Dev , vol.7 , Issue.3 , pp. 187-195
    • Summerton, J.1    Weller, D.2
  • 76
    • 0030808415 scopus 로고    scopus 로고
    • Progress in developing PNA as a gene-targeteddrug
    • Good, L.; Nielsen, P. E., Progress in developing PNA as a gene-targeteddrug. Antisense Nucleic Acid Drug Dev., 1997, 7(4), 431-437.
    • (1997) Antisense Nucleic Acid Drug Dev , vol.7 , Issue.4 , pp. 431-437
    • Good, L.1    Nielsen, P.E.2
  • 77
    • 0034078048 scopus 로고    scopus 로고
    • Peptide nucleic acid (PNA): Its medical andbiotechnical applications and promise for the future
    • Ray, A.; Norden, B., Peptide nucleic acid (PNA): its medical andbiotechnical applications and promise for the future. FASEB J., 2000, 14(9),1041-1060.
    • (2000) FASEB J , vol.14 , Issue.9 , pp. 1041-1060
    • Ray, A.1    Norden, B.2
  • 78
    • 34250679056 scopus 로고    scopus 로고
    • Locked nucleic acid oligonucleotides: Thenext generation of antisense agents?
    • Grunweller, A.; Hartmann, R., Locked nucleic acid oligonucleotides: thenext generation of antisense agents? BioDrugs, 2007, 21(4), 235-243.
    • (2007) BioDrugs , vol.21 , Issue.4 , pp. 235-243
    • Grunweller, A.1    Hartmann, R.2
  • 79
    • 0036567147 scopus 로고    scopus 로고
    • Design of antisenseoligonucleotides stabilized by locked nucleic acids
    • Kurreck, J.; Wyszko, E.; Gillen, C.; Erdmann, V., Design of antisenseoligonucleotides stabilized by locked nucleic acids. Nucleic Acids Res., 2002,30(9), 1911-1918.
    • (2002) Nucleic Acids Res , vol.30 , Issue.9 , pp. 1911-1918
    • Kurreck, J.1    Wyszko, E.2    Gillen, C.3    Erdmann, V.4
  • 81
    • 0033754176 scopus 로고    scopus 로고
    • Influence ofdifferent chelators (HYNIC, MAG 3 and DTPA) on tumor cell accumulationand mouse biodistribution of technetium-99m labeled to antisense DNA
    • Zhang, Y.; Liu, N.; Zhu, Z.; Rusckowski, M.; Hnatowich, D., Influence ofdifferent chelators (HYNIC, MAG 3 and DTPA) on tumor cell accumulationand mouse biodistribution of technetium-99m labeled to antisense DNA. Eur. J. Nucl. Med. Mol. Imaging, 2000, 27(11), 1700-1707.
    • (2000) Eur. J. Nucl. Med. Mol. Imaging , vol.27 , Issue.11 , pp. 1700-1707
    • Zhang, Y.1    Liu, N.2    Zhu, Z.3    Rusckowski, M.4    Hnatowich, D.5
  • 82
    • 0035209382 scopus 로고    scopus 로고
    • Invitro investigations of tumor targeting with 99mTc-labeled antisense DNA
    • Zhang, Y.; Wang, Y.; Liu, N.; Zhu, Z.; Rusckowski, M.; Hnatowich, D., Invitro investigations of tumor targeting with 99mTc-labeled antisense DNA. J. Nucl. Med., 2001, 42(11), 1660-1669.
    • (2001) J. Nucl. Med , vol.42 , Issue.11 , pp. 1660-1669
    • Zhang, Y.1    Wang, Y.2    Liu, N.3    Zhu, Z.4    Rusckowski, M.5    Hnatowich, D.6
  • 83
    • 0026174658 scopus 로고
    • The clearance and degradation of oligodeoxynucleotides following intravenous injection into rabbits
    • Goodchild, J.; Kim, B.; Zamecnik, P. C., The clearance and degradation of oligodeoxynucleotides following intravenous injection into rabbits. Antisense Res. Dev., 1991, 1(2), 153-160.
    • (1991) Antisense Res. Dev , vol.1 , Issue.2 , pp. 153-160
    • Goodchild, J.1    Kim, B.2    Zamecnik, P.C.3
  • 84
    • 0024449939 scopus 로고
    • Partial protection of oncogene, anti-senseoligodeoxynucleotides against serum nuclease degradation using terminalmethylphosphonate groups
    • Tidd, D. M.; Warenius, H. M., Partial protection of oncogene, anti-senseoligodeoxynucleotides against serum nuclease degradation using terminalmethylphosphonate groups. Br. J. Cancer, 1989, 60(3), 343-350.
    • (1989) Br. J. Cancer , vol.60 , Issue.3 , pp. 343-350
    • Tidd, D.M.1    Warenius, H.M.2
  • 85
    • 0026073646 scopus 로고
    • Modifieddeoxyoligonucleotides stable to exonuclease degradation in serum
    • Shaw, J. P.; Kent, K.; Bird, J.; Fishback, J.; Froehler, B., Modifieddeoxyoligonucleotides stable to exonuclease degradation in serum. NucleicAcids Res., 1991, 19(4), 747-750.
    • (1991) Nucleic Acids Res , vol.19 , Issue.4 , pp. 747-750
    • Shaw, J.P.1    Kent, K.2    Bird, J.3    Fishback, J.4    Froehler, B.5
  • 86
    • 0024296609 scopus 로고
    • Physicochemicalproperties of phosphorothioate oligodeoxynucleotides
    • Stein, C. A.; Subasinghe, C.; Shinozuka, K.; Cohen, J. S., Physicochemicalproperties of phosphorothioate oligodeoxynucleotides. Nucleic Acids Res.,1988, 16(8), 3209-3221.
    • (1988) Nucleic Acids Res , vol.16 , Issue.8 , pp. 3209-3221
    • Stein, C.A.1    Subasinghe, C.2    Shinozuka, K.3    Cohen, J.S.4
  • 87
    • 0029420163 scopus 로고
    • Enzymatic degradation ofvarious antisense oligonucleotides: Monitoring and fragment identificationby MECC and ES-MS
    • Maier, M.; Bleicher, K.; Kalthoff, H.; Bayer, E., Enzymatic degradation ofvarious antisense oligonucleotides: monitoring and fragment identificationby MECC and ES-MS. Biomed. Pept. Proteins Nucleic Acids, 1995, 1(4),235-42.
    • (1995) Biomed Pept. Proteins Nucleic Acids , vol.1 , Issue.4 , pp. 235-242
    • Maier, M.1    Bleicher, K.2    Kalthoff, H.3    Bayer, E.4
  • 88
    • 0026585659 scopus 로고
    • In vivostability and kinetics of absorption and disposition of 3'phosphopropyl amineoligonucleotides
    • Zendegui, J.; Vasquez, K.; Tinsley, J.; Kessler, D.; Hogan, M., In vivostability and kinetics of absorption and disposition of 3'phosphopropyl amineoligonucleotides. Nucleic acids Res., 1992, 20(2), 307-314.
    • (1992) Nucleic Acids Res , vol.20 , Issue.2 , pp. 307-314
    • Zendegui, J.1    Vasquez, K.2    Tinsley, J.3    Kessler, D.4    Hogan, M.5
  • 90
    • 0030960680 scopus 로고    scopus 로고
    • Pharmacokinetic considerations in the development ofoligomers as radiopharmaceuticals
    • Hnatowich, D. J., Pharmacokinetic considerations in the development ofoligomers as radiopharmaceuticals. Q. J. Nucl. Med., 1997, 41(2), 91-100.
    • (1997) Q. J. Nucl. Med , vol.41 , Issue.2 , pp. 91-100
    • Hnatowich, D.J.1
  • 92
    • 0032697941 scopus 로고    scopus 로고
    • Two problems in antisense biotechnology: In vitro delivery and thedesign of antisense experiments
    • Stein, C., Two problems in antisense biotechnology: in vitro delivery and thedesign of antisense experiments. Biochim. Biophys. Acta., 1999, 1489(1), 45-52.
    • (1999) Biochim. Biophys Acta , vol.1489 , Issue.1 , pp. 45-52
    • Stein, C.1
  • 93
    • 0032998423 scopus 로고    scopus 로고
    • Keeping the biotechnology of antisense in context
    • Stein, C., Keeping the biotechnology of antisense in context. Nat.Biotechnol., 1999, 17, 209-209.
    • (1999) Nat. Biotechnol , vol.17 , pp. 209
    • Stein, C.1
  • 94
    • 0029086725 scopus 로고
    • Characterization of bindingsites, extent of binding, and drug interactions of oligonucleotides withalbumin
    • Srinivasan, S. K.; Tewary, H. K.; Iversen, P. L., Characterization of bindingsites, extent of binding, and drug interactions of oligonucleotides withalbumin. Antisense Res. Dev., 1995, 5(2), 131-139.
    • (1995) Antisense Res. Dev , vol.5 , Issue.2 , pp. 131-139
    • Srinivasan, S.K.1    Tewary, H.K.2    Iversen, P.L.3
  • 95
    • 0028845327 scopus 로고
    • Binding of phosphorothioateoligodeoxynucleotides to basic fibroblast growth factor, recombinant solubleCD4, laminin and fibronectin is P-chirality independent
    • Benimetskaya, L.; Tonkinson, J. L.; Koziolkiewicz, M.; Karwowski, B.; Guga, P.; Zeltser, R.; Stec, W.; Stein, C. A., Binding of phosphorothioateoligodeoxynucleotides to basic fibroblast growth factor, recombinant solubleCD4, laminin and fibronectin is P-chirality independent. Nucleic Acids Res.,1995, 23(21), 4239-4245.
    • (1995) Nucleic Acids Res , vol.23 , Issue.21 , pp. 4239-4245
    • Benimetskaya, L.1    Tonkinson, J.L.2    Koziolkiewicz, M.3    Karwowski, B.4    Guga, P.5    Zeltser, R.6    Stec, W.7    Stein, C.A.8
  • 96
    • 0029828410 scopus 로고    scopus 로고
    • Interaction of oligodeoxynucleotides withmammalian cells
    • Hawley, P.; Gibson, I., Interaction of oligodeoxynucleotides withmammalian cells. Antisense Nucleic Acid Drug Dev., 1996, 6(3), 185-195.
    • (1996) Antisense Nucleic Acid Drug Dev , vol.6 , Issue.3 , pp. 185-195
    • Hawley, P.1    Gibson, I.2
  • 98
    • 0026839585 scopus 로고
    • Analysis of oligonucleotide binding, internalization, and intracellular trafficking utilizing a novel radiolabeledcrosslinker
    • Geselowitz, D. A.; Neckers, L. M., Analysis of oligonucleotide binding,internalization, and intracellular trafficking utilizing a novel radiolabeledcrosslinker. Antisense Res. Dev., 1992, 2(1), 17-25.
    • (1992) Antisense Res. Dev , vol.2 , Issue.1 , pp. 17-25
    • Geselowitz, D.A.1    Neckers, L.M.2
  • 99
    • 0038629103 scopus 로고    scopus 로고
    • In vivo imaging with oligonucleotides for diagnosis and drugdevelopment
    • Tavitian, B., In vivo imaging with oligonucleotides for diagnosis and drugdevelopment. Gut, 2003, 52, (Suppl 4), iv40-iv47.
    • (2003) Gut , vol.52 , Issue.SUPPL. 4
    • Tavitian, B.1
  • 101
    • 0025169744 scopus 로고
    • Quantitative study of tyrosine hydroxylase mRNAin catecholaminergic neurons and adrenals during development and aging
    • Kedzierski, W.; Porter, J., Quantitative study of tyrosine hydroxylase mRNAin catecholaminergic neurons and adrenals during development and aging. Brain Res. Mol. Brain Res., 1990, 7(1), 45-51.
    • (1990) Brain Res. Mol. Brain Res , vol.7 , Issue.1 , pp. 45-51
    • Kedzierski, W.1    Porter, J.2
  • 102
    • 0027968772 scopus 로고
    • Endomyocardial gene expression during development ofpacing tachycardia-induced heart failure in the dog
    • Williams, R.; Kass, D.; Kawagoe, Y.; Pak, P.; Tunin, R.; Shah, R.; Hwang,A.; Feldman, A., Endomyocardial gene expression during development ofpacing tachycardia-induced heart failure in the dog. Circ. Res., 1994, 75(4),615-623.
    • (1994) Circ. Res , vol.75 , Issue.4 , pp. 615-623
    • Williams, R.1    Kass, D.2    Kawagoe, Y.3    Pak, P.4    Tunin, R.5    Shah, R.6    Hwang, A.7    Feldman, A.8
  • 103
    • 4644318647 scopus 로고    scopus 로고
    • Antisense targeting in cell culture withradiolabeled DNAs--a brief review of recent progress
    • Hnatowich, D. J.; Nakamura, K., Antisense targeting in cell culture withradiolabeled DNAs--a brief review of recent progress. Ann. Nucl. Med.,2004, 18(5), 363-368.
    • (2004) Ann. Nucl. Med , vol.18 , Issue.5 , pp. 363-368
    • Hnatowich, D.J.1    Nakamura, K.2
  • 105
    • 17844397735 scopus 로고    scopus 로고
    • Antisense targeting of Pglycoproteinexpression in tissue culture
    • Nakamura, K.; Kubo, A.; Hnatowich, D., Antisense targeting of Pglycoproteinexpression in tissue culture. J. Nucl. Med., 2005, 46(3), 509-513.
    • (2005) J. Nucl. Med , vol.46 , Issue.3 , pp. 509-513
    • Nakamura, K.1    Kubo, A.2    Hnatowich, D.3
  • 106
    • 0035216893 scopus 로고    scopus 로고
    • Cationicliposomes enhance cellular/nuclear localization of 99mTc-antisenseoligonucleotides in target tumor cells
    • Zhang, Y.; Rusckowski, M.; Liu, N.; Liu, C.; Hnatowich, D., Cationicliposomes enhance cellular/nuclear localization of 99mTc-antisenseoligonucleotides in target tumor cells. Cancer Biother. Radiopharm., 2001,16(5), 411-419.
    • (2001) Cancer Biother. Radiopharm , vol.16 , Issue.5 , pp. 411-419
    • Zhang, Y.1    Rusckowski, M.2    Liu, N.3    Liu, C.4    Hnatowich, D.5
  • 107
    • 0002326455 scopus 로고
    • Hybridization: Considerations affecting antisense drugs
    • CRC Press, Boca Raton, FL
    • Freier, S., Hybridization: considerations affecting antisense drugs. Antisense Research and Applications. CRC Press, Boca Raton, FL, 1993, 67-82.
    • (1993) Antisense Research and Applications , pp. 67-82
    • Freier, S.1
  • 108
    • 0036294559 scopus 로고    scopus 로고
    • Labelled oligonucleotides asradiopharmaceuticals: Pitfalls, problems and perspectives
    • Younes, C.; Boisgard, R.; Tavitian, B., Labelled oligonucleotides asradiopharmaceuticals: pitfalls, problems and perspectives. Curr. Pharm.Des., 2002, 8(16), 1451-1466.
    • (2002) Curr. Pharm.Des , vol.8 , Issue.16 , pp. 1451-1466
    • Younes, C.1    Boisgard, R.2    Tavitian, B.3
  • 109
    • 0034739609 scopus 로고    scopus 로고
    • Novel non-endocytic delivery of antisenseoligonucleotides
    • Dokka, S.; Rojanasakul, Y., Novel non-endocytic delivery of antisenseoligonucleotides. Adv. Drug Deliv. Rev., 2000, 44(1), 35-49.
    • (2000) Adv. Drug Deliv. Rev , vol.44 , Issue.1 , pp. 35-49
    • Dokka, S.1    Rojanasakul, Y.2
  • 110
    • 0026688472 scopus 로고
    • Antisense c-mycoligodeoxyribonucleotide cellular uptake
    • Wu-Pong, S.; Weiss, T.; Hunt, C., Antisense c-mycoligodeoxyribonucleotide cellular uptake. Pharm. Res., 1992, 9, 1010-1017.
    • (1992) Pharm. Res , vol.9 , pp. 1010-1017
    • Wu-Pong, S.1    Weiss, T.2    Hunt, C.3
  • 111
    • 0028584316 scopus 로고
    • Antisense c-myc oligonucleotide cellularuptake and activity
    • Wu-Pong, S.; Weiss, T.; Hunt, C., Antisense c-myc oligonucleotide cellularuptake and activity. Antisense Res. Dev., 1994, 4(3), 155-163.
    • (1994) Antisense Res. Dev , vol.4 , Issue.3 , pp. 155-163
    • Wu-Pong, S.1    Weiss, T.2    Hunt, C.3
  • 112
    • 0027161566 scopus 로고
    • Dynamics of the internalization of phosphodiesteroligodeoxynucleotides in HL60 cells
    • Stein, C.; Tonkinson, J.; Zhang, L.; Yakubov, L.; Gervasoni, J.; Taub, R.; Rotenberg, S., Dynamics of the internalization of phosphodiesteroligodeoxynucleotides in HL60 cells. Biochemistry, 1993, 32(18), 4855-4861.
    • (1993) Biochemistry , vol.32 , Issue.18 , pp. 4855-4861
    • Stein, C.1    Tonkinson, J.2    Zhang, L.3    Yakubov, L.4    Gervasoni, J.5    Taub, R.6    Rotenberg, S.7
  • 115
    • 33646738061 scopus 로고    scopus 로고
    • Oligonucleotide-modified gold nanoparticles for intracellular generegulation
    • Rosi, N.; Giljohann, D.; Thaxton, C.; Lytton-Jean, A.; Han, M.; Mirkin, C., Oligonucleotide-modified gold nanoparticles for intracellular generegulation. Science, 2006, 312(5776), 1027-1030.
    • (2006) Science , vol.312 , Issue.5776 , pp. 1027-1030
    • Rosi, N.1    Giljohann, D.2    Thaxton, C.3    Lytton-Jean, A.4    Han, M.5    Mirkin, C.6
  • 117
    • 0026490041 scopus 로고
    • Intracellular availability of unmodified, phosphorothioated and liposomally encapsulated oligodeoxynucleotides forantisense activity
    • Thierry, A. R.; Dritschilo, A., Intracellular availability of unmodified,phosphorothioated and liposomally encapsulated oligodeoxynucleotides forantisense activity. Nucleic Acids Res., 1992, 20(21), 5691-5698.
    • (1992) Nucleic Acids Res , vol.20 , Issue.21 , pp. 5691-5698
    • Thierry, A.R.1    Dritschilo, A.2
  • 118
    • 0025398291 scopus 로고
    • Biological activity of oligonucleotidepoly(L-lysine) conjugates: Mechanism of cell uptake
    • Leonetti, J. P.; Degols, G.; Lebleu, B., Biological activity of oligonucleotidepoly(L-lysine) conjugates: mechanism of cell uptake. Bioconjug. Chem.,1990, 1(2), 149-153.
    • (1990) Bioconjug. Chem , vol.1 , Issue.2 , pp. 149-153
    • Leonetti, J.P.1    Degols, G.2    Lebleu, B.3
  • 119
    • 0028220371 scopus 로고
    • Inhibition ofleukaemia cell proliferation by folic acid-polylysine-mediated introduction ofc-myb antisense oligodeoxynucleotides into HL-60 cells
    • Citro, G.; Szczylik, C.; Ginobbi, P.; Zupi, G.; Calabretta, B., Inhibition ofleukaemia cell proliferation by folic acid-polylysine-mediated introduction ofc-myb antisense oligodeoxynucleotides into HL-60 cells. Br. J. Cancer,1994, 69(3), 463-467.
    • (1994) Br. J. Cancer , vol.69 , Issue.3 , pp. 463-467
    • Citro, G.1    Szczylik, C.2    Ginobbi, P.3    Zupi, G.4    Calabretta, B.5
  • 120
    • 31544448890 scopus 로고    scopus 로고
    • Comparative Evaluation ofTarget-Specific GFP Gene Silencing Efficiencies for Antisense ODN,Synthetic siRNA, and siRNA Plasmid Complexed with PEI- PEG- FOLConjugate
    • Kim, S.; Mok, H.; Jeong, J.; Kim, S.; Park, T., Comparative Evaluation ofTarget-Specific GFP Gene Silencing Efficiencies for Antisense ODN,Synthetic siRNA, and siRNA Plasmid Complexed with PEI- PEG- FOLConjugate. Bioconjug. Chem., 2006, 17(1), 241-244.
    • (2006) Bioconjug. Chem , vol.17 , Issue.1 , pp. 241-244
    • Kim, S.1    Mok, H.2    Jeong, J.3    Kim, S.4    Park, T.5
  • 121
    • 0242494161 scopus 로고    scopus 로고
    • A new antisense oligonucleotide delivery systembased on self-assembled ODNñPEG hybrid conjugate micelles
    • Jeong, J.; Kim, S.; Park, T., A new antisense oligonucleotide delivery systembased on self-assembled ODNñPEG hybrid conjugate micelles. J. Control.Release, 2003, 93(2), 183-191.
    • (2003) J. Control.Release , vol.93 , Issue.2 , pp. 183-191
    • Jeong, J.1    Kim, S.2    Park, T.3
  • 122
    • 1542511346 scopus 로고    scopus 로고
    • Evaluation of generation 2 and 3 poly(propylenimine) dendrimers for the potential cellular delivery of antisenseoligonucleotides targeting the epidermal growth factor receptor
    • Hollins, A.; Benboubetra, M.; Omidi, Y.; Zinselmeyer, B.; Schatzlein, A.; Uchegbu, I.; Akhtar, S., Evaluation of generation 2 and 3 poly(propylenimine) dendrimers for the potential cellular delivery of antisenseoligonucleotides targeting the epidermal growth factor receptor. Pharm. Res.,2004, 21(3), 458-466.
    • (2004) Pharm. Res , vol.21 , Issue.3 , pp. 458-466
    • Hollins, A.1    Benboubetra, M.2    Omidi, Y.3    Zinselmeyer, B.4    Schatzlein, A.5    Uchegbu, I.6    Akhtar, S.7
  • 123
    • 0002863889 scopus 로고    scopus 로고
    • Poly (ethylene glycol)-blockpoly(L-lysine) dendrimer: Novel linear polymer/dendrimer block copolymerforming a spherical water-soluble polyionic complex with DNA
    • Choi, J.; Lee, E.; Choi, Y.; Jeong, Y.; Park, J., Poly (ethylene glycol)-blockpoly(L-lysine) dendrimer: novel linear polymer/dendrimer block copolymerforming a spherical water-soluble polyionic complex with DNA. Bioconjug.Chem., 1999, 10(1), 62-65.
    • (1999) Bioconjug.Chem , vol.10 , Issue.1 , pp. 62-65
    • Choi, J.1    Lee, E.2    Choi, Y.3    Jeong, Y.4    Park, J.5
  • 124
    • 0027382982 scopus 로고
    • Inhibition of the Friend retrovirus byantisense oligonucleotides encapsulated in liposomes: Mechanism of action
    • Ropert, C.; Malvy, C.; Couvreur, P., Inhibition of the Friend retrovirus byantisense oligonucleotides encapsulated in liposomes: mechanism of action.Pharm. Res., 1993, 10(10), 1427-33.
    • (1993) Pharm. Res , vol.10 , Issue.10 , pp. 1427-1433
    • Ropert, C.1    Malvy, C.2    Couvreur, P.3
  • 125
    • 0028924955 scopus 로고
    • Delivery ofantisense oligodeoxyribonucleotides against the human epidermal growthfactor receptor into cultured KB cells with liposomes conjugated to folate viapolyethylene glycol
    • Wang, S.; Lee, R. J.; Cauchon, G.; Gorenstein, D. G.; Low, P. S., Delivery ofantisense oligodeoxyribonucleotides against the human epidermal growthfactor receptor into cultured KB cells with liposomes conjugated to folate viapolyethylene glycol. Proc. Natl. Acad. Sci. U S A, 1995, 92(8), 3318-3322.
    • (1995) Proc. Natl. Acad. Sci. U S A , vol.92 , Issue.8 , pp. 3318-3322
    • Wang, S.1    Lee, R.J.2    Cauchon, G.3    Gorenstein, D.G.4    Low, P.S.5
  • 126
    • 0031811763 scopus 로고    scopus 로고
    • Membrane fusionplays an important role in gene transfection mediated by cationic liposomes
    • Noguchi, A.; Furuno, T.; Kawaura, C.; Nakanishi, M., Membrane fusionplays an important role in gene transfection mediated by cationic liposomes. FEBS Lett., 1998, 433(1-2), 169-173.
    • (1998) FEBS Lett , vol.433 , Issue.1-2 , pp. 169-173
    • Noguchi, A.1    Furuno, T.2    Kawaura, C.3    Nakanishi, M.4
  • 127
    • 0035989886 scopus 로고    scopus 로고
    • Oligonucleotide conjugates as potential antisense drugs withimproved uptake, biodistribution, targeted delivery, and mechanism ofaction
    • Manoharan, M., Oligonucleotide conjugates as potential antisense drugs withimproved uptake, biodistribution, targeted delivery, and mechanism ofaction. Antisense Nucleic Acid Drug Dev., 2002, 12(2), 103-128.
    • (2002) Antisense Nucleic Acid Drug Dev , vol.12 , Issue.2 , pp. 103-128
    • Manoharan, M.1
  • 129
    • 33747762229 scopus 로고    scopus 로고
    • Exploiting the enhancedpermeability and retention effect for tumor targeting
    • Iyer, A.; Khaled, G.; Fang, J.; Maeda, H., Exploiting the enhancedpermeability and retention effect for tumor targeting. Drug Discov. Today,2006, 11(17-18), 812-818.
    • (2006) Drug Discov. Today , vol.11 , Issue.17-18 , pp. 812-818
    • Iyer, A.1    Khaled, G.2    Fang, J.3    Maeda, H.4
  • 130
    • 0026877363 scopus 로고
    • Liposomes as a drug delivery system for antisenseoligonucleotides
    • Juliano, R.; Akhtar, S., Liposomes as a drug delivery system for antisenseoligonucleotides. Antisense Res. Dev., 1992, 2(2), 165-176.
    • (1992) Antisense Res. Dev , vol.2 , Issue.2 , pp. 165-176
    • Juliano, R.1    Akhtar, S.2
  • 131
    • 33747877757 scopus 로고    scopus 로고
    • In Vitro and In Vivo Intracellular Liposomal Delivery of Antisenseoligonucleotides and Anticancer Drug
    • Pakunlu, R.; Wang, Y.; Saad, M.; Khandare, J.; Starovoytov, V.; Minko, T., In vitro and in vivo intracellular liposomal delivery of antisenseoligonucleotides and anticancer drug. J. Control. Release, 2006, 114(2), 153-162.
    • (2006) J. Control. Release , vol.114 , Issue.2 , pp. 153-162
    • Pakunlu, R.1    Wang, Y.2    Saad, M.3    Khandare, J.4    Starovoytov, V.5    Minko, T.6
  • 132
    • 0030222163 scopus 로고    scopus 로고
    • Liposomes as a carrier for intracellular delivery ofantisense oligonucleotides: A real or magic bullet
    • Zelphati, O.; Szoka, F., Liposomes as a carrier for intracellular delivery ofantisense oligonucleotides: a real or magic bullet? J. Control. Release, 1996,41(1-2), 99-119.
    • (1996) J. Control. Release , vol.41 , Issue.1-2 , pp. 99-119
    • Zelphati, O.1    Szoka, F.2
  • 133
    • 0031739308 scopus 로고    scopus 로고
    • Optimallipofection reagent varies with the molecular modifications of the DNA
    • Conrad, A. H.; Behlke, M. A.; Jaffredo, T.; Conrad, G. W., Optimallipofection reagent varies with the molecular modifications of the DNA. Antisense Nucleic Acid Drug Dev., 1998, 8(5), 427-34.
    • (1998) Antisense Nucleic Acid Drug Dev , vol.8 , Issue.5 , pp. 427-434
    • Conrad, A.H.1    Behlke, M.A.2    Jaffredo, T.3    Conrad, G.W.4
  • 134
    • 0028077713 scopus 로고
    • Cationic lipid is not required for uptake and selective inhibitory activity ofICAM-1 phosphorothioate antisense oligonucleotides in keratinocytes
    • Nestle, F. O.; Mitra, R. S.; Bennett, C. F.; Chan, H.; Nickoloff, B. J.,Cationic lipid is not required for uptake and selective inhibitory activity ofICAM-1 phosphorothioate antisense oligonucleotides in keratinocytes. J.Invest. Dermatol., 1994, 103(4), 569-575.
    • (1994) J.Invest. Dermatol , vol.103 , Issue.4 , pp. 569-575
    • Nestle, F.O.1    Mitra, R.S.2    Bennett, C.F.3    Chan, H.4    Nickoloff, B.J.5
  • 136
    • 0030670810 scopus 로고    scopus 로고
    • Toxicity and immunomodulatory activity ofliposomal vectors formulated with cationic lipids toward immune effectorcells
    • Filion, M.; Phillips, N., Toxicity and immunomodulatory activity ofliposomal vectors formulated with cationic lipids toward immune effectorcells. Biochim. Biophys. Acta., 1997, 1329(2), 345-356.
    • (1997) Biochim. Biophys. Acta , vol.1329 , Issue.2 , pp. 345-356
    • Filion, M.1    Phillips, N.2
  • 137
    • 0036112087 scopus 로고    scopus 로고
    • Characterization of syntheticanionic vector for oligonucleotide delivery using in vivo whole bodydynamic imaging
    • Tavitian, B.; Marzabal, S.; Boutet, V.; Ķhnast, B.; Terrazzino, S.; Moynier, M.; DollÈ, F.; Deverre, J.; Thierry, A., Characterization of syntheticanionic vector for oligonucleotide delivery using in vivo whole bodydynamic imaging. Pharm. Res., 2002, 19(4), 367-376.
    • (2002) Pharm. Res , vol.19 , Issue.4 , pp. 367-376
    • Tavitian, B.1    Marzabal, S.2    Boutet, V.3    Ķhnast, B.4    Terrazzino, S.5    Moynier, M.6    Ollè, F.7    Deverre, J.8    Thierry, A.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.