-
1
-
-
0027376439
-
Anti-sense oligonucleotides as therapeutic agents - Is the bullet really magical?
-
Stein C.A., Cheng Y.C. Anti-sense oligonucleotides as therapeutic agents - is the bullet really magical? Science. 261:1993;1004-1012.
-
(1993)
Science
, vol.261
, pp. 1004-1012
-
-
Stein, C.A.1
Cheng, Y.C.2
-
2
-
-
0027481659
-
Progress toward oligonucleotide therapeutics: Pharmacodynamic properties
-
Crooke S.T. Progress toward oligonucleotide therapeutics: pharmacodynamic properties. FASEB J. 7:1993;533-539.
-
(1993)
FASEB J.
, vol.7
, pp. 533-539
-
-
Crooke, S.T.1
-
3
-
-
0032147234
-
Nucleic acid therapeutics: State of the art and future prospects
-
Gewirtz A.M., Sokol D.L., Ratajczak M.Z. Nucleic acid therapeutics: state of the art and future prospects. Blood. 92:1998;712-736.
-
(1998)
Blood
, vol.92
, pp. 712-736
-
-
Gewirtz, A.M.1
Sokol, D.L.2
Ratajczak, M.Z.3
-
4
-
-
0031912506
-
Anti-sense oligonucleotides: Is the glass half full or half empty?
-
Bennett C.F. Anti-sense oligonucleotides: is the glass half full or half empty? Biochem. Pharmacol. 55:1998;9-19.
-
(1998)
Biochem. Pharmacol.
, vol.55
, pp. 9-19
-
-
Bennett, C.F.1
-
6
-
-
0029768861
-
Anti-sense oligodeoxynucleotide combination therapy of primary chronic myelogenous leukemia blast crisis in SCID mice
-
Skorski T., Nieborowska-Skorska M., Wlodarski P., Zon G., Iozzo R.V., Calabretta B. Anti-sense oligodeoxynucleotide combination therapy of primary chronic myelogenous leukemia blast crisis in SCID mice. Blood. 88:1996;1005-1012.
-
(1996)
Blood
, vol.88
, pp. 1005-1012
-
-
Skorski, T.1
Nieborowska-Skorska, M.2
Wlodarski, P.3
Zon, G.4
Iozzo, R.V.5
Calabretta, B.6
-
7
-
-
0028219485
-
Inhibition of vascular smooth muscle cell proliferation in vitro and in vivo by c-myc anti-sense oligodeoxynucleotides
-
Bennett M.R., Anglin S., McEwan J.R., Jagoe R., Newby A.C., Evan G.I. Inhibition of vascular smooth muscle cell proliferation in vitro and in vivo by c-myc anti-sense oligodeoxynucleotides. J. Clin. Invest. 93:1994;820-828.
-
(1994)
J. Clin. Invest.
, vol.93
, pp. 820-828
-
-
Bennett, M.R.1
Anglin, S.2
Mcewan, J.R.3
Jagoe, R.4
Newby, A.C.5
Evan, G.I.6
-
8
-
-
0026641052
-
Anti-sense c-myc oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo
-
Simons M., Edelman E.R., DeKeyser J.L., Langer R., Rogenberg R.D. Anti-sense c-myc oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo. Nature. 359:1992;67-70.
-
(1992)
Nature
, vol.359
, pp. 67-70
-
-
Simons, M.1
Edelman, E.R.2
Dekeyser, J.L.3
Langer, R.4
Rogenberg, R.D.5
-
9
-
-
0028019410
-
Gene inhibition using anti-sense oligodeoxynucleotides
-
Wagner R.W. Gene inhibition using anti-sense oligodeoxynucleotides. Nature. 372:1994;333-335.
-
(1994)
Nature
, vol.372
, pp. 333-335
-
-
Wagner, R.W.1
-
10
-
-
0031683544
-
Folate-mediated targeting of antisense oligodeoxynucleotides to ovarian cancer cells
-
Li S., Deshmukh H.M., Huang L. Folate-mediated targeting of antisense oligodeoxynucleotides to ovarian cancer cells. Pharm. Res. 15:1998;1540-1545.
-
(1998)
Pharm. Res.
, vol.15
, pp. 1540-1545
-
-
Li, S.1
Deshmukh, H.M.2
Huang, L.3
-
11
-
-
0023755696
-
Oligodeoxy-nucleoside phosphoramidates and phosphorothioates as inhibitors of human immunodeficiency virus
-
Agrawal S., Goodchild J., Civeira M.P., Thornton A.H., Sarin P.S., Zamecnik P.C. Oligodeoxy-nucleoside phosphoramidates and phosphorothioates as inhibitors of human immunodeficiency virus. Proc. Natl. Acad. Sci. U. S. A. 85:1988;7079-7083.
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, pp. 7079-7083
-
-
Agrawal, S.1
Goodchild, J.2
Civeira, M.P.3
Thornton, A.H.4
Sarin, P.S.5
Zamecnik, P.C.6
-
12
-
-
0027364174
-
PNA hybridizes to complementary oligo-nucleotides obeying the Watson-Crick hydrogen bonding rules
-
Egholm M., Buchardt O., Christensen L., Behrens C., Frier S.M., Driver D.A., Berg R.H., Kim S.K., Norde'n B., Nielsen P.E. PNA hybridizes to complementary oligo-nucleotides obeying the Watson-Crick hydrogen bonding rules. Nature. 365:1993;566-568.
-
(1993)
Nature
, vol.365
, pp. 566-568
-
-
Egholm, M.1
Buchardt, O.2
Christensen, L.3
Behrens, C.4
Frier, S.M.5
Driver, D.A.6
Berg, R.H.7
Kim, S.K.8
Norde'n, B.9
Nielsen, P.E.10
-
13
-
-
0034594649
-
Delivery of c-myb anti-sense oligodeoxynucleotides to human neuroblastoma cells via disialoganglioside GD 2-targeted immunoliposomes: Antitumor effects
-
Pagnan G., Stuart D.D., Pastorino F., Raffaghello L., Montaldo P.G., Allen T.M., Calabretta B., Ponzoni M. Delivery of c-myb anti-sense oligodeoxynucleotides to human neuroblastoma cells via disialoganglioside GD 2-targeted immunoliposomes: antitumor effects. J. Natl. Cancer Inst. 92:2000;253-261.
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 253-261
-
-
Pagnan, G.1
Stuart, D.D.2
Pastorino, F.3
Raffaghello, L.4
Montaldo, P.G.5
Allen, T.M.6
Calabretta, B.7
Ponzoni, M.8
-
14
-
-
0026877363
-
Liposomes as a drug delivery system for anti-sense oligonucleotides
-
Juliano R.L., Akhtar S. Liposomes as a drug delivery system for anti-sense oligonucleotides. Antisense Res. Dev. 2:1992;165-176.
-
(1992)
Antisense Res. Dev.
, vol.2
, pp. 165-176
-
-
Juliano, R.L.1
Akhtar, S.2
-
15
-
-
0032546804
-
Cationic liposomes coated with polyethylene glycol as carriers for oligonucleotides
-
Meyer O., Kirpotin D., Hong K., Sternberg B., Park J.W., Woodlei M.C., Papahadjopoulos D. Cationic liposomes coated with polyethylene glycol as carriers for oligonucleotides. J. Biol. Chem. 25:1998;15621-15627.
-
(1998)
J. Biol. Chem.
, vol.25
, pp. 15621-15627
-
-
Meyer, O.1
Kirpotin, D.2
Hong, K.3
Sternberg, B.4
Park, J.W.5
Woodlei, M.C.6
Papahadjopoulos, D.7
-
16
-
-
0032580531
-
A new non-viral DNA delivery vector: The terplex system
-
Kim J.S., Kim B.-I., Maruyama A., Akaike T., Kim S.W. A new non-viral DNA delivery vector: the terplex system. J. Control. Release. 53:1998;175-182.
-
(1998)
J. Control. Release
, vol.53
, pp. 175-182
-
-
Kim, J.S.1
Kim, B.-I.2
Maruyama, A.3
Akaike, T.4
Kim, S.W.5
-
17
-
-
0029160083
-
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
-
Boussif O., Lezoualc'h F., Zanta M.A., Mergny M.D., Scheman D., Demeneix B., Behr J.P. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc. Natl. Acad. Sci. U. S. A. 92:1995;7297-7303.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 7297-7303
-
-
Boussif, O.1
Lezoualc'h, F.2
Zanta, M.A.3
Mergny, M.D.4
Scheman, D.5
Demeneix, B.6
Behr, J.P.7
-
18
-
-
0026536219
-
Polyalkylcyanoacrylate nanoparticles as polymeric carriers for antisense oligonucleotides
-
Chavany C., Doan T.L., Couvreur P., Puisieux F., Helene C. Polyalkylcyanoacrylate nanoparticles as polymeric carriers for antisense oligonucleotides. Pharm. Res. 9:1992;441-449.
-
(1992)
Pharm. Res.
, vol.9
, pp. 441-449
-
-
Chavany, C.1
Doan, T.L.2
Couvreur, P.3
Puisieux, F.4
Helene, C.5
-
19
-
-
0030385934
-
Spontaneous formation of polyion complex micelles with narrow distribution from anti-sense oligonucleotide and cationic block copolymer in physiological saline
-
Kataoka K., Togawa H., Harada A., Yasugi K., Matsumoto T., Katoyose S. Spontaneous formation of polyion complex micelles with narrow distribution from anti-sense oligonucleotide and cationic block copolymer in physiological saline. Macromolecules. 29:1996;8556-8557.
-
(1996)
Macromolecules
, vol.29
, pp. 8556-8557
-
-
Kataoka, K.1
Togawa, H.2
Harada, A.3
Yasugi, K.4
Matsumoto, T.5
Katoyose, S.6
-
20
-
-
0031239718
-
Water-soluble polyion complex associates of DNA and poly(ethyeneglycol)- poly(L-lysine) block copolymer
-
Katayose S., Kataoka K. Water-soluble polyion complex associates of DNA and poly(ethyeneglycol)-poly(L-lysine) block copolymer. Bioconjug. Chem. 8:1997;702-707.
-
(1997)
Bioconjug. Chem.
, vol.8
, pp. 702-707
-
-
Katayose, S.1
Kataoka, K.2
-
21
-
-
0031938986
-
Remarkable increase in nuclease resistance of plasmid DNA through supramolecular assembly with poly(ethyleneglycol)-poly(L-lysine) block copolymer
-
Katayose S., Kataoka K. Remarkable increase in nuclease resistance of plasmid DNA through supramolecular assembly with poly(ethyleneglycol)-poly(L- lysine) block copolymer. J. Pharm. Sci. 87:1998;160-163.
-
(1998)
J. Pharm. Sci.
, vol.87
, pp. 160-163
-
-
Katayose, S.1
Kataoka, K.2
-
22
-
-
0035080570
-
Physicochemical properties and nuclease resistance of anti-sense-oligonucleotides entrapped in the core of polyion complex micelles composed of poly(ethyeneglycol)-poly(L-lysine) block copolymer
-
Harada A., Togawa H., Kataoka K. Physicochemical properties and nuclease resistance of anti-sense-oligonucleotides entrapped in the core of polyion complex micelles composed of poly(ethyeneglycol)-poly(L-lysine) block copolymer. Eur. J. Pharm. Sci. 13:2001;35-42.
-
(2001)
Eur. J. Pharm. Sci.
, vol.13
, pp. 35-42
-
-
Harada, A.1
Togawa, H.2
Kataoka, K.3
-
23
-
-
0034885217
-
Glutathione-sensitive stabilization of block copolymer micelles composed of antisense DNA and thiolated poly(ethylene glycol)-block-poly(L-lysine): A potential carrier for systemic delivery of antisense DNA
-
Kakizawa Y., Harada A., Kataoka K. Glutathione-sensitive stabilization of block copolymer micelles composed of antisense DNA and thiolated poly(ethylene glycol)-block-poly(L-lysine): a potential carrier for systemic delivery of antisense DNA. Biomacromolecules. 2:2001;491-497.
-
(2001)
Biomacromolecules
, vol.2
, pp. 491-497
-
-
Kakizawa, Y.1
Harada, A.2
Kataoka, K.3
-
24
-
-
0032213191
-
Self-assembly of polyamine-poly(ethylene glycol) copolymers with phosphorothioate oligonucleotides
-
Vinogradov S.V., Bronich T.K., Kabanov A.V. Self-assembly of polyamine-poly(ethylene glycol) copolymers with phosphorothioate oligonucleotides. Bioconjug. Chem. 9:1998;805-812.
-
(1998)
Bioconjug. Chem.
, vol.9
, pp. 805-812
-
-
Vinogradov, S.V.1
Bronich, T.K.2
Kabanov, A.V.3
-
25
-
-
0033199351
-
Polyion complex micelles with protein-modified corona for receptor-mediated delivery of oligonucleotides into cells
-
Vinogradof S., Batrakova E., Li S., Kabanov A. Polyion complex micelles with protein-modified corona for receptor-mediated delivery of oligonucleotides into cells. Bioconjug. Chem. 10:1999;851-860.
-
(1999)
Bioconjug. Chem.
, vol.10
, pp. 851-860
-
-
Vinogradof, S.1
Batrakova, E.2
Li, S.3
Kabanov, A.4
-
26
-
-
0001451822
-
Characterization of a targeted gene carrier, lactose-polyethylene glycol-grafted poly-L-lysine, and its complex with plasmid DNA
-
Choi Y.H., Liu F., Choi J.S., Kim S.W., Park J.S. Characterization of a targeted gene carrier, lactose-polyethylene glycol-grafted poly-L-lysine, and its complex with plasmid DNA. Hum. Gene Ther. 10:1999;2657-2665.
-
(1999)
Hum. Gene Ther.
, vol.10
, pp. 2657-2665
-
-
Choi, Y.H.1
Liu, F.2
Choi, J.S.3
Kim, S.W.4
Park, J.S.5
-
27
-
-
0035845729
-
A new gene delivery formulation of polyethyleneimine/DNA complexes coated with PEG conjugated fusogenic peptide
-
Lee H., Jeong J.H., Park T.G. A new gene delivery formulation of polyethyleneimine/DNA complexes coated with PEG conjugated fusogenic peptide. J. Control. Release. 76:2001;138-192.
-
(2001)
J. Control. Release
, vol.76
, pp. 138-192
-
-
Lee, H.1
Jeong, J.H.2
Park, T.G.3
-
28
-
-
0037133097
-
PEG grafted polylysine with fusogenic peptide for gene delivery: High transfection efficiency with low cytotoxicity
-
Lee H., Jeong J.H., Park T.G. PEG grafted polylysine with fusogenic peptide for gene delivery: high transfection efficiency with low cytotoxicity. J. Control. Release. 79:2002;283-291.
-
(2002)
J. Control. Release
, vol.79
, pp. 283-291
-
-
Lee, H.1
Jeong, J.H.2
Park, T.G.3
-
29
-
-
0035210220
-
Novel polymer-DNA hybrid polymeric micelles composed of hydrophobic poly(D,L-lactic-co-glycolic acid) and hydrophilic oligonucleotides
-
Jeong J.H., Park T.G. Novel polymer-DNA hybrid polymeric micelles composed of hydrophobic poly(D,L-lactic-co-glycolic acid) and hydrophilic oligonucleotides. Bioconjug. Chem. 12:2001;917-923.
-
(2001)
Bioconjug. Chem.
, vol.12
, pp. 917-923
-
-
Jeong, J.H.1
Park, T.G.2
-
30
-
-
0037344136
-
Novel intra-cellular delivery system of anti-sense oligonucleotide by self-assembled hybrid micelles composed of DNA/PEG conjugate and cationic fusogenic peptide
-
Jeong J.H., Kim S.W., Park T.G. Novel intra-cellular delivery system of anti-sense oligonucleotide by self-assembled hybrid micelles composed of DNA/ PEG conjugate and cationic fusogenic peptide. Bioconjug. Chem. 14:2003;473-479.
-
(2003)
Bioconjug. Chem.
, vol.14
, pp. 473-479
-
-
Jeong, J.H.1
Kim, S.W.2
Park, T.G.3
-
31
-
-
0029977448
-
Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against c-Raf kinase
-
Monia B.P., Johnston J.F., Geiger T., Muller M., Fabbro D. Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against c-Raf kinase. Nat. Med. 2:1996;668-675.
-
(1996)
Nat. Med.
, vol.2
, pp. 668-675
-
-
Monia, B.P.1
Johnston, J.F.2
Geiger, T.3
Muller, M.4
Fabbro, D.5
-
32
-
-
0035977185
-
Association of c-Raf expression with survival and its targeting with antisense oligonucleotides in ovarian cancer
-
McPhillips F., Mullen P., Monia B.P., Ritchie A.A., Dorr F.A., Smyth J.F., Langdon S.P. Association of c-Raf expression with survival and its targeting with antisense oligonucleotides in ovarian cancer. Br. J. Cancer. 85:2001;1753-1758.
-
(2001)
Br. J. Cancer
, vol.85
, pp. 1753-1758
-
-
Mcphillips, F.1
Mullen, P.2
Monia, B.P.3
Ritchie, A.A.4
Dorr, F.A.5
Smyth, J.F.6
Langdon, S.P.7
-
33
-
-
0032984099
-
Phase I clinical/pharmacokinetic and pharmacodynamic trial of the c-raf-1 antisense oligonucleotide ISIS 5132 (CGP 69846A)
-
Stevenson J.P., Yao K.S., Gallagher M., Friedland D., Mitchell E.P., Cassella A., Monia B., Kwoh T.J., Yu R., Holmlund J., Dorr F.A., O'Dwyer P.J. Phase I clinical/pharmacokinetic and pharmacodynamic trial of the c-raf-1 antisense oligonucleotide ISIS 5132 (CGP 69846A). J. Clin. Oncol. 17:1999;2227-2236.
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 2227-2236
-
-
Stevenson, J.P.1
Yao, K.S.2
Gallagher, M.3
Friedland, D.4
Mitchell, E.P.5
Cassella, A.6
Monia, B.7
Kwoh, T.J.8
Yu, R.9
Holmlund, J.10
Dorr, F.A.11
O'dwyer, P.J.12
-
34
-
-
0034026007
-
A phase I trial of c-Raf kinase antisense oligonucleotide ISIS 5132 administered as a continuous intravenous infusion in patients with advanced cancer
-
Cunningham C.C., Holmlund J.T., Schiller J.H., Geary R.S., Kwoh T.J., Dorr A., Nemunaitis J. A phase I trial of c-Raf kinase antisense oligonucleotide ISIS 5132 administered as a continuous intravenous infusion in patients with advanced cancer. Clin. Cancer Res. 6:2000;1626-1631.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 1626-1631
-
-
Cunningham, C.C.1
Holmlund, J.T.2
Schiller, J.H.3
Geary, R.S.4
Kwoh, T.J.5
Dorr, A.6
Nemunaitis, J.7
-
35
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assay
-
Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assay. J. Immunol. Methods. 65:1983;55-63.
-
(1983)
J. Immunol. Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
36
-
-
0032973777
-
Permeation of PEO-PBLA-FITC polymeric micelles in aortic endothelial cells
-
Liaw J., Aoyagi T., Kataoka K., Sakurai Y., Okano T. Permeation of PEO-PBLA-FITC polymeric micelles in aortic endothelial cells. Pharm. Res. 16:1999;213-220.
-
(1999)
Pharm. Res.
, vol.16
, pp. 213-220
-
-
Liaw, J.1
Aoyagi, T.2
Kataoka, K.3
Sakurai, Y.4
Okano, T.5
-
37
-
-
0028104204
-
The ins and outs of raf kinases
-
Daum G., Eisenmann-Tapp I., Fries H.-W., Troppmair J., Rapp U.R. The ins and outs of raf kinases. TIBS. 19:1994;474-480.
-
(1994)
TIBS
, vol.19
, pp. 474-480
-
-
Daum, G.1
Eisenmann-Tapp, I.2
Fries, H.-W.3
Troppmair, J.4
Rapp, U.R.5
-
38
-
-
0034000453
-
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: A review
-
Maeda H., Wu J., Saga T., Matsumura Y., Hori K. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J. Control. Release. 65:2000;271-284.
-
(2000)
J. Control. Release
, vol.65
, pp. 271-284
-
-
Maeda, H.1
Wu, J.2
Saga, T.3
Matsumura, Y.4
Hori, K.5
|