Antisense imaging: Where are we now?

Cancer Biotherapy and Radiopharmaceuticals

Volumn 15, Issue 5, 2000, Pages 447-457

  Hnatowich, D J ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Antisense; Imaging

Indexed keywords

COMPLEMENTARY DNA; LIPID; LIPOSOME; MESSENGER RNA; OLIGOMER; TECHNETIUM 99M;

CHEMOTHERAPY; CLONING VECTOR; DNA HYBRIDIZATION; GENE TARGETING; GENE THERAPY; HUMAN; IMAGING; ISOTOPE LABELING; NONHUMAN; PRIORITY JOURNAL; REVIEW;

EID: 0033695063     PISSN: 10849785     EISSN: None     Source Type: Journal    
DOI: 10.1089/cbr.2000.15.447     Document Type: Review

References (53)

1. Novel mechanisms for antisense-mediated regulation of gene expression
2. Isis and antisense face crucial test without Novartis
3. Human Bcl-2 antisense therapy for lymphomas
4. A placebo-controlled trial of ICAM-1 antisense oligonucleotide in the treatment of Crohn's disease
5. c-raf-1 Depletion and tumor responses in patients treated with the c-raf-1 antisense oligonucleotide ISIS 5132 (CGP 69846A)
6. Gene therapy using antisense oligodeoxynucleotides labeled with auger-emitting radionuclides
7. Antisense and Nuclear Medicine
8. Novel mechanisms for antisense-mediated regulation of gene expression
9. Therapeutic delivery issues in gene therapy. Part I: Vectors
10. Antisense therapeutics: Is it as simple as complementary base recognition?
11. Morpholino antisense oligomers: Design, preparation and properties
12. Morpholino antisense oligomers: The case for an RNase H-independent structural type
13. A theoretical approach to select effective atnisense oligodeoxyribnucleotides at high statistical probability
14. Walking along human c-myc mRNA with antisense oligonucleotides: Maximum efficacy at the 5' cap region
15. Molecular mechanism of action of antisense drugs
16. A specificity comparison of four antisense types: Morpholino, 2'-O-methy RNA, DNA and phosphorothioate DNA
17. Advantages of 2'-O-methyl oligoribonucleotide probes for detecting RNA targets
18. Absolute quantitation of specific mRNAs in cell and tissue samples by comparative PCR
19. Measurements of low-abundance cytokine mRNA in cells of murine lymphoid organs: A new quantitative reverse transcription/polymerase chain reaction method
20. Serial analysis of gene expression
21. Tantalizing transcriptomes-SAGE and its use in global gene expression analysis
22. Characterization of the yeast transcriptome
23. Dynamics of gene expression revealed by comparison of serial analysis of gene expression transcript profiles from yeast grown on two different carbon sources
24. Imaging gene expression: Principles and assays
25. Validation and application of a solid-phase chemistry method for preparing high effective specific activity technetium-99m radiopharmaceuticals
26. Convenient preparation of no-carrier-added technetium-99m radiopharmaceuticals using solid-phase technology
27. Radioimmunodiagnosis and therapy
28. Noninvasive imaging of c-myc oncogene messenger RNA with indium-111-antisense probes in a mammary tumor-bearing mouse model
29. In vivo hybridization of technetium-99m-labeled peptide nucleic acid (PNA)
30. Technetium-99m labeling of DNA oligonucleotides
31. Scintigraphic imaging of oncogenes with antisense probes: Does it make sense?
32. A high production rate of translatable IgG mRNA accounts for the amplified synthesis of IgG in myeloma cells
33. Antisense RNA gene therapy for studying and modulating biological process
34. Synthetic DNA delivery systems
35. Development and analysis of recombinant adenoviruses for gene therapy of cystic fibrosis
36. Gene therapy safety issues come to the fore
37. Cationic liposomes coated with polyethylene glycon as carriers for oligonucleotides
38. Antisense oligonucleotides directed against the viral RNA polymerase gene enhance survival of mice infected with influence A
39. Nucleic acid therapeutics: State of the art and future prospects
40. Liposomes revisited
41. Antibody-targeted liposomes containing oligodeoxyribonucleotides complementary to viral RNA selectively inhibit viral replication
42. Liposomes containing synthetic lipid derivitives of poly(ethylene glycol) show prolonged circulation half-times in vivo
43. Molecular conjugates: A targeted gene delivery vector for molecular medicine
44. 111ln-labeled antisense oligodeoxynucleotide probes by high-pressure liquid chromatography
45. In vivo hybridization of technetium-99m-labeled peptide nucleic acid (PNA)
46. m-labeled oligodeoxynucleotide to CAPL RNA
47. In vivo imaging of oligonucleotides with positron emission tomography
48. Real-time biospecific interaction analysis using surface plasmon resonance and a sensor chip technology
49. Site-selective cyclic AMP analogs provide a new approach in the control of cancer cell growth
50. In vitro repression by a site-specific DNA-binding protein designed against an oncogenic sequence
51. aHIF: A natural antisense trasncript overexpressed in human renal cancer and during hypoxia
52. Heat shock-induced myocardial protection against ischemic injury: A role for Hsp 70?