Poly(ethylene glycol)-block-poly(L-lysine) dendrimer: Novel linear polymer/dendrimer block copolymer forming a spherical water-soluble polyionic complex with DNA

Bioconjugate Chemistry

Volumn 10, Issue 1, 1999, Pages 62-65

  Choi, Joon Sig ^a   Lee, Eun Jung ^a   Choi, Young Hun ^a   Jeong, Yong Joo ^a   Park, Jong Sang ^a  

^a Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ATOMIC FORCE MICROSCOPY; BIOMOLECULES; DENDRIMERS; DNA; ELECTROPHORESIS; ETHYLENE; ETHYLENE GLYCOL; MASS SPECTROMETRY; POLYETHYLENE GLYCOLS; POLYOLS; SYNTHESIS (CHEMICAL);

BLOCK CO POLYMERS; LINEAR POLYMERS; LIQUID PHASE; LIQUID PHASIS; PEPTIDE SYNTHESIS; PLASMID DNA; POLY-L-LYSINE; SYNTHESISED; WATER-SOLUBLE COMPLEXES; WATERSOLUBLE;

BLOCK COPOLYMERS;

EID: 0002863889     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc9800668     Document Type: Article

References (12)

1. Kataoka, K., Kwon, G. S., Yokoyama, M., Okano, T., and Sakurai, Y. (1993) Block copolymer micelles as vehicles for drug delivery. J. Controlled Release 24, 119-132.
2. Gref, R., Minamitake, Y., Peracchia, M. T., Trubetskoy, V., Torchilin, V., and Langer, R. (1994) Biodegradable Long-Circulating Polymeric Nanospheres. Science 263, 1600-1603.
3. Wolfert, M. A., Schacht, E. H., Toncheva, V., Ulbrich, K., Nazarova, O., and Seymour, L. W. (1996) Characterization of Vectors for Gene Therapy Formed by Self-Assembly of DNA with Synthetic Block Co-polymers. Hum. Gene Ther. 7, 2123-2133.
4. Kabanov, A. V., Vinogradov, S. V., Suzdaltseva, Y. G., and Alakhov, V. Y. (1995) Water-Soluble Block Polycations as Carriers for Oligonucleotide Delivery. Bioconjugate Chem. 6, 639-643.
5. Choi, Y. H., Liu, F., Kim, J. S., Choi, Y. K., Park, J. S., and Kim, S. W. (1998) Poly(ethylene glycol)-grafted poly-L-lysine as polymeric gene carrier. J. Controlled Release 54, 39-48.
6. Katayose, S., and Kataoka, K. (1997) Water-Soluble Polyion Complex Associates of DNA and Poly(ethylene glycol)-Poly-(L-lysine) Block Copolymer. Bioconjugate Chem. 8, 702-707.
7. Kataoka, K., Togawa, H., Harada, A., Yasugi, K., Matsumoto, T., and Katayose, S. (1996) Spontaneous Formation of Polyion Complex Micelles with Narrow Distribution from Antisense Oligonucleotide and Cationic Block Copolymer in Physiological Saline. Macromolecules 29, 8556-8557.
8. Bielinska, A., Kukowska-Latallo, J. F., Johnson, J., Tomalia, D. A., and Baker, J. R. (1996) Regulation of in vitro gene expression using antisense oligonucleotides or antisense expression plasmids transfected using starburst PAMAM dendrimers. Nucleic Acids Res. 24, 2176-2182.
9. Tang, M. X., Redemann, C. T., and Szoka, F. C. (1996) In Vitro Gene Delivery by Degraded Polyamidoamine Dendrimers. Bioconjugate Chem. 7, 703-714.
10. Bayer, E., and Mutter, M. (1979) The Liquid-Phase Method for Peptide Synthesis. in The Peptides (Gross, E., and Meienhofer, J., Eds.) Vol. 2, pp 285-332, Academic Press, New York.
11. Aharoni, S. M., Crosby, C. R., III, and Walsh, E. K. (1982) Size and Solution Properties of Globular tert-Butyloxycarbonyl-poly(α,ε-L-lysine). Macromolecules 15, 1093-1098.
12. Adami, R. C., Collard, W. T., Gupta, S. A., Kwok, K. Y., Bonadio, J., and Rice, K. G. (1998) Stability of Peptide-Condensed Plasmid DNA Formulations. J. Pharm. Sci. 87, 678-683.