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Volumn 52, Issue SUPPL. 4, 2003, Pages

In vivo imaging with oligonucleotides for diagnosis and drug development

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CARBON 11; DACARBAZINE; DEOXYRIBONUCLEOSIDE; FLUORINE 18; FOMIVIRSEN; IODINE 125; NITROGEN 13; OBLIMERSEN; OLIGONUCLEOTIDE; OXYGEN 15; PHOSPHOROTHIOIC ACID DERIVATIVE; RADIOISOTOPE; RADIOPHARMACEUTICAL AGENT; RNA; TRACER;

EID: 0038629103     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.52.suppl_4.iv40     Document Type: Conference Paper
Times cited : (77)

References (112)
  • 1
    • 0029890055 scopus 로고    scopus 로고
    • The imaging science of positron emission tomography
    • Jones T. The imaging science of positron emission tomography. Eur J Nuc Med 1996;23:807-13.
    • (1996) Eur J Nuc Med , vol.23 , pp. 807-813
    • Jones, T.1
  • 2
    • 0035282803 scopus 로고    scopus 로고
    • In vivo pharmacokinetics and pharmacodynamics in drug development using positron-emission tomography
    • Aboagye EO, Price PM, Jones T. In vivo pharmacokinetics and pharmacodynamics in drug development using positron-emission tomography. Drug Discov Today 2001;6:293-302.
    • (2001) Drug Discov Today , vol.6 , pp. 293-302
    • Aboagye, E.O.1    Price, P.M.2    Jones, T.3
  • 4
    • 0025074907 scopus 로고
    • In vitro selection of RNA molecules that bind specific ligands
    • Ellington AD, Szostak JW. In vitro selection of RNA molecules that bind specific ligands. Nature 1990;346:818-22.
    • (1990) Nature , vol.346 , pp. 818-822
    • Ellington, A.D.1    Szostak, J.W.2
  • 5
    • 0025194307 scopus 로고
    • Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
    • Tuerk C, Gold L. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 1990;249:505-10.
    • (1990) Science , vol.249 , pp. 505-510
    • Tuerk, C.1    Gold, L.2
  • 7
    • 0014132623 scopus 로고
    • Synthesis of ribonucleosides and diribonucleoside phosphates containing 2-chloro-ethylamine and nitrogen mustard residues
    • Beilkova A, Zarytova V, Grineva N. Synthesis of ribonucleosides and diribonucleoside phosphates containing 2-chloro-ethylamine and nitrogen mustard residues. Tetrahedron Lett 1967;8:3557-62.
    • (1967) Tetrahedron Lett , vol.8 , pp. 3557-3562
    • Belikova, A.1    Zarytova, V.2    Grineva, N.3
  • 8
    • 0027376439 scopus 로고
    • Antisense oligonucleotides as therapeutic agents: Is the bullet really magical?
    • Stein CA, Cheng YC. Antisense oligonucleotides as therapeutic agents: is the bullet really magical? Science 1993;261:1004-12.
    • (1993) Science , vol.261 , pp. 1004-1012
    • Stein, C.A.1    Cheng, Y.C.2
  • 9
    • 0025279948 scopus 로고
    • Analytical study of phosphorothioate analogues of oligodeoxynucleotides using high-performance liquid chromatography
    • Agrawal S, Tang JY, Brown DM. Analytical study of phosphorothioate analogues of oligodeoxynucleotides using high-performance liquid chromatography. J Chromatogr 1990;509:396-9.
    • (1990) J Chromatogr , vol.509 , pp. 396-399
    • Agrawal, S.1    Tang, J.Y.2    Brown, D.M.3
  • 10
    • 0025175236 scopus 로고
    • Disposition and metabolism of oligodeoxynucleoside methylphosphonate following a single iv injection in mice
    • Chen T-L, Miller PS, Tso PO, et al. Disposition and metabolism of oligodeoxynucleoside methylphosphonate following a single iv injection in mice. Drug Metab Dispos 1990;18:815-18.
    • (1990) Drug Metab Dispos , vol.18 , pp. 815-818
    • Chen, T.-L.1    Miller, P.S.2    Tso, P.O.3
  • 11
    • 0026588983 scopus 로고
    • Increased specificity for antisense oligodeoxynucleotide targeting of RNA cleavage by RNase H using chimeric methylphosphonodiester/phosphodiester structures
    • Giles RV, Tidd DM. Increased specificity for antisense oligodeoxynucleotide targeting of RNA cleavage by RNase H using chimeric methylphosphonodiester/phosphodiester structures. Nucleic Acids Res 1992;20:763-70.
    • (1992) Nucleic Acids Res , vol.20 , pp. 763-770
    • Giles, R.V.1    Tidd, D.M.2
  • 12
    • 0027981259 scopus 로고
    • Resistance to degradation by nucleases of (2′S)-2′-deoxy-2′-C-methyloligonucleotides, novel potential antisense probes
    • Iribarren AM, Cicero DO, Neuner PJ. Resistance to degradation by nucleases of (2′S)-2′-deoxy-2′-C-methyloligonucleotides, novel potential antisense probes. Antisense Res Dev 1994;4:95-8.
    • (1994) Antisense Res Dev , vol.4 , pp. 95-98
    • Iribarren, A.M.1    Cicero, D.O.2    Neuner, P.J.3
  • 13
    • 0028043181 scopus 로고
    • Synthesis of 3′-C-(hydroxymethyl)thymidine - Introduction of a novel class of deoxynucleosides and oligodeoxynucleotides
    • Jorgensen PN, Stein PC, Wengel J. Synthesis of 3′-C-(hydroxymethyl)thymidine - Introduction of a novel class of deoxynucleosides and oligodeoxynucleotides. J Am Chem Soc 1994;116:2231-2.
    • (1994) J Am Chem Soc , vol.116 , pp. 2231-2232
    • Jorgensen, P.N.1    Stein, P.C.2    Wengel, J.3
  • 14
    • 14744277298 scopus 로고
    • Oligonucleoside methylphosphonates as antisense reagents
    • Miller PS. Oligonucleoside methylphosphonates as antisense reagents. BioTechnology 1991;9:358-62.
    • (1991) BioTechnology , vol.9 , pp. 358-362
    • Miller, P.S.1
  • 15
    • 0026474678 scopus 로고
    • RNase H-mediated inhibition of translation by antisense oligodeoxyribonucleotides: Use of backbone modification to improve specificity
    • Larrouy B, Blonski C, Boiziau C, et al. RNase H-mediated inhibition of translation by antisense oligodeoxyribonucleotides: use of backbone modification to improve specificity. Gene 1992;121:189-94.
    • (1992) Gene , vol.121 , pp. 189-194
    • Larrouy, B.1    Blonski, C.2    Boiziau, C.3
  • 16
    • 0027479864 scopus 로고
    • Uniformly modified 2′-deoxy-2′-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets
    • Kawosaki AM, Casper MD, Freier SM, et al. Uniformly modified 2′-deoxy-2′-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets. J Med Chem 1993;36:831-41.
    • (1993) J Med Chem , vol.36 , pp. 831-841
    • Kawasaki, A.M.1    Casper, M.D.2    Freier, S.M.3
  • 17
    • 0027168725 scopus 로고
    • Evaluation of 2′-modified oligonucleotides containing 2′-deoxy gaps as antisense inhibitors of gene expression
    • Monia BP, Lesnik EA, Gonzalez C, et al. Evaluation of 2′-modified oligonucleotides containing 2′-deoxy gaps as antisense inhibitors of gene expression. J Biol Chem 1993;268:14514-22.
    • (1993) J Biol Chem , vol.268 , pp. 14514-14522
    • Monia, B.P.1    Lesnik, E.A.2    Gonzalez, C.3
  • 18
    • 0028038592 scopus 로고
    • Peptide nucleic acid (PNA) - A DNA mimic with a peptide backbone
    • Nielsen PE, Egholm M, Buchardt O. Peptide nucleic acid (PNA) - a DNA mimic with a peptide backbone. Bioconj Chem 1994;5:3-7.
    • (1994) Bioconj Chem , vol.5 , pp. 3-7
    • Nielsen, P.E.1    Egholm, M.2    Buchardt, O.3
  • 19
    • 0028968912 scopus 로고
    • Site and mechanism of antisense inhibition by C.5 propyne oligonucleotides
    • Moulds C, Lewis JG, Froehler BC, et al. Site and mechanism of antisense inhibition by C.5 propyne oligonucleotides. Biochemistry 1995;34:5044-53.
    • (1995) Biochemistry , vol.34 , pp. 5044-5053
    • Moulds, C.1    Lewis, J.G.2    Froehler, B.C.3
  • 20
    • 0029100397 scopus 로고
    • Absorption, tissue distribution and in vivo stability in rats of a hybrid antisense oligonucleotide following oral administration
    • Agrawal S, Zhang X, Lu Z, et al. Absorption, tissue distribution and in vivo stability in rats of a hybrid antisense oligonucleotide following oral administration. Biochem Pharmacol 1995;50:571-6.
    • (1995) Biochem Pharmacol , vol.50 , pp. 571-576
    • Agrawal, S.1    Zhang, X.2    Lu, Z.3
  • 21
    • 0027240213 scopus 로고
    • Antisense oligodeoxynucleotides: Synthesis, biophysical and biological evaluation of oligodeoxynucleotides containing modified pyrimidines
    • Sanghvi YS, Hoke GD, Freier SM, et al. Antisense oligodeoxynucleotides: synthesis, biophysical and biological evaluation of oligodeoxynucleotides containing modified pyrimidines. Nucleic Acids Res 1993;1:3197-203.
    • (1993) Nucleic Acids Res , vol.1 , pp. 3197-3203
    • Sanghvi, Y.S.1    Hoke, G.D.2    Freier, S.M.3
  • 22
    • 0030747101 scopus 로고    scopus 로고
    • A specificity comparison of four antisense types: Morpholino, 2′-O-methyl RNA, DNA, and phosphorothioate DNA
    • Stein D, Foster E, Huang SB, et al. A specificity comparison of four antisense types: morpholino, 2′-O-methyl RNA, DNA, and phosphorothioate DNA. Antisense Nucleic Acid Drug Dev 1997;7:151-7.
    • (1997) Antisense Nucleic Acid Drug Dev , vol.7 , pp. 151-157
    • Stein, D.1    Foster, E.2    Huang, S.B.3
  • 23
    • 0034746953 scopus 로고    scopus 로고
    • Phosphoramidate oligonucleotides as potent antisense molecules in cells and in vivo
    • Faria M, Spiller DG, Dubertret C, et al. Phosphoramidate oligonucleotides as potent antisense molecules in cells and in vivo. Nat Biotechnol 2001;19:40-4.
    • (2001) Nat Biotechnol , vol.19 , pp. 40-44
    • Faria, M.1    Spiller, D.G.2    Dubertret, C.3
  • 24
    • 0027325137 scopus 로고
    • Comparison of cellular binding and uptake of antisense phosphodiester, phosphorothioate, and mixed phosphorothioate and methylphosphonate oligonucleotides
    • Zhao Q, Matson S, Herrera CJ, et al. Comparison of cellular binding and uptake of antisense phosphodiester, phosphorothioate, and mixed phosphorothioate and methylphosphonate oligonucleotides. Antisense Res Dev 1993;3:53-66.
    • (1993) Antisense Res Dev , vol.3 , pp. 53-66
    • Zhao, Q.1    Matson, S.2    Herrera, C.J.3
  • 25
    • 0033789658 scopus 로고    scopus 로고
    • In vivo antisense imaging
    • 200
    • Tavitian B. In vivo antisense imaging. Q J Nucl Med 200;44:236-55.
    • Q J Nucl Med , vol.44 , pp. 236-255
    • Tavitian, B.1
  • 26
    • 0036294559 scopus 로고    scopus 로고
    • Labelled oligonucleotides as radiopharmaceuticals: Pitfalls, problems and perspectives
    • Younes CK, Boisgard R, Tavitian B. Labelled oligonucleotides as radiopharmaceuticals: pitfalls, problems and perspectives. Curr Pharm Des 2002;8:1451-66.
    • (2002) Curr Pharm Des , vol.8 , pp. 1451-1466
    • Younes, C.K.1    Boisgard, R.2    Tavitian, B.3
  • 27
    • 0024570173 scopus 로고
    • Development of a stable radioiodinating reagant to label monoclonal antibodies for radiotherapy of cancer
    • Wilbur DS, Hadley SW, Hylarides MD, et al. Development of a stable radioiodinating reagant to label monoclonal antibodies for radiotherapy of cancer. J Nucl Med 1989;30:216-26.
    • (1989) J Nucl Med , vol.30 , pp. 216-226
    • Wilbur, D.S.1    Hadley, S.W.2    Hylarides, M.D.3
  • 29
    • 0033794909 scopus 로고    scopus 로고
    • A general method to label antisense oligonucleotides with radioactive halogens for pharmacological and imaging studies
    • Kühnast B, Dollé F, Terrazzino S, et al. A general method to label antisense oligonucleotides with radioactive halogens for pharmacological and imaging studies. Bioconj Chem 2000;11:627-36.
    • (2000) Bioconj Chem , vol.11 , pp. 627-636
    • Kühnast, B.1    Dollé, F.2    Terrazzino, S.3
  • 30
    • 0034042803 scopus 로고    scopus 로고
    • Fluorine-18 labeling of oligonucleotides bearing chemically - Modified ribose · phosphate backbones
    • Kühnast B, Dollé F, Vaufrey F, et al. Fluorine-18 labeling of oligonucleotides bearing chemically - modified ribose · phosphate backbones. J Label Compounds Radiopharm 2000;43:837-48.
    • (2000) J Label Compounds Radiopharm , vol.43 , pp. 837-848
    • Kühnast, B.1    Dollé, F.2    Vaufrey, F.3
  • 32
    • 0030943935 scopus 로고    scopus 로고
    • Comparative pharmacokinetics, tissue distribution, and tumor accumulation of phosphorothioate, phosphorodithioate, and methylphosphonate oligonucleotides in nude mice
    • DeLong RK, Nohing A, Fisher M, et al. Comparative pharmacokinetics, tissue distribution, and tumor accumulation of phosphorothioate, phosphorodithioate, and methylphosphonate oligonucleotides in nude mice. Antisense Nucleic Acid Drug Dev 1997;7:71-7.
    • (1997) Antisense Nucleic Acid Drug Dev , vol.7 , pp. 71-77
    • DeLong, R.K.1    Nolting, A.2    Fisher, M.3
  • 33
    • 0030863191 scopus 로고    scopus 로고
    • A competitive enzyme hybridization assay for plasma determination of phosphodiester and phosphorothioate antisense oligonucleotide
    • Deverre JR, Boutet V, Boquet, et al. A competitive enzyme hybridization assay for plasma determination of phosphodiester and phosphorothioate antisense oligonucleotide. Nucleic Acids Res 1997;25:3584-9.
    • (1997) Nucleic Acids Res , vol.25 , pp. 3584-3589
    • Deverre, J.R.1    Boutet, V.2    Boquet3
  • 34
    • 0031948547 scopus 로고    scopus 로고
    • In vivo imaging of oligonucleotides with positron emission tomography
    • Tavitian B, Terrazzino S, Kühnast B, et al. In vivo imaging of oligonucleotides with positron emission tomography. Nat Med 1998;4:467-71.
    • (1998) Nat Med , vol.4 , pp. 467-471
    • Tavitian, B.1    Terrazzino, S.2    Kühnast, B.3
  • 35
    • 0035209382 scopus 로고    scopus 로고
    • In vitro investigations of tumor targeting with (99m)Tc-labeled antisense DNA
    • Zhang YM, Wang Y, Liu N, et al. In vitro investigations of tumor targeting with (99m)Tc-labeled antisense DNA. J Nucl Med 2001;42:1660-9.
    • (2001) J Nucl Med , vol.42 , pp. 1660-1669
    • Zhang, Y.M.1    Wang, Y.2    Liu, N.3
  • 36
    • 0033754176 scopus 로고    scopus 로고
    • Influence of different chelators (HYNIC, MAG3 and DTPA) on tumor cell accumulation and mouse biodistribution of technetium-99m labeled to antisense DNA
    • Zhang YM, Liu N, Zhu ZH, et al. Influence of different chelators (HYNIC, MAG3 and DTPA) on tumor cell accumulation and mouse biodistribution of technetium-99m labeled to antisense DNA. Eur J Nucl Med 2000;27:1700-7.
    • (2000) Eur J Nucl Med , vol.27 , pp. 1700-1707
    • Zhang, Y.M.1    Liu, N.2    Zhu, Z.H.3
  • 37
    • 0005772676 scopus 로고
    • Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide
    • Stephenson ML, Zamecnik PC. Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide. Proc Natl Acad Sci USA 1978;75:285-8.
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 285-288
    • Stephenson, M.L.1    Zamecnik, P.C.2
  • 38
    • 0033003665 scopus 로고    scopus 로고
    • Changing focus: Applying antisense to nuclear medicine imaging
    • Hnatowich DJ. Changing focus: applying antisense to nuclear medicine imaging. Mol Med Today 1999;5:151.
    • (1999) Mol Med Today , vol.5 , pp. 151
    • Hnatowich, D.J.1
  • 39
    • 0031027349 scopus 로고    scopus 로고
    • In vivo studies with antisense oligonucleotides
    • Akhtar S, Agrawal S. In vivo studies with antisense oligonucleotides. Trends Pharmacol Sci 1997;18:12-18.
    • (1997) Trends Pharmacol Sci , vol.18 , pp. 12-18
    • Akhtar, S.1    Agrawal, S.2
  • 42
    • 0037616861 scopus 로고    scopus 로고
    • http://www.trilinkbiotech.com/newsite/Technical_Info/ Articles/pdfs/antisense_oligo_primer.pdf
  • 43
    • 0032743841 scopus 로고    scopus 로고
    • Oligonucleotide therapeutics for hematologic disorders
    • Agarwal N, Gewirtz AM. Oligonucleotide therapeutics for hematologic disorders. Biochim Biophys Acta 1999;1489:85-96.
    • (1999) Biochim Biophys Acta , vol.1489 , pp. 85-96
    • Agarwal, N.1    Gewirtz, A.M.2
  • 44
    • 0032079761 scopus 로고    scopus 로고
    • BCR-ABL antisense oligodeoxynucleotide in vitro purging and autologous bone marrow transplantation for patients with chronic myelogenous leukemia in advanced phase
    • de Fabritiis P, Petti MC, Montefusco E, et al. BCR-ABL antisense oligodeoxynucleotide in vitro purging and autologous bone marrow transplantation for patients with chronic myelogenous leukemia in advanced phase. Blood 1998;91:3156-62.
    • (1998) Blood , vol.91 , pp. 3156-3162
    • De Fabritiis, P.1    Petti, M.C.2    Montefusco, E.3
  • 45
    • 0027070730 scopus 로고
    • In vivo treatment of human leukemia in a scid mouse model with c-myb antisense oligodeoxynucleotides
    • Ratajczak MZ, Kant JA, Luger SM, et al. In vivo treatment of human leukemia in a scid mouse model with c-myb antisense oligodeoxynucleotides. Proc Natl Acad Sci USA 1992;89:11823-7.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11823-11827
    • Ratajczak, M.Z.1    Kant, J.A.2    Luger, S.M.3
  • 46
    • 9244223546 scopus 로고    scopus 로고
    • Phase I trial of an antisense oligonucleotide OL(1)p53 in hematologic malignancies
    • Bishop MR, Iversen PL, Bayever E, et al. Phase I trial of an antisense oligonucleotide OL(1)p53 in hematologic malignancies. J Clin Oncol 1996;14:1320-6.
    • (1996) J Clin Oncol , vol.14 , pp. 1320-1326
    • Bishop, M.R.1    Iversen, P.L.2    Bayever, E.3
  • 47
    • 0026754351 scopus 로고
    • Acute- and chronic-phase chronic myelogenous leukemia colony-forming units are highly sensitive to the growth inhibitory effects of c-myb antisense oligodeoxynucleotides
    • Ratajczak MZ, Hijiya N, Catani L, et al. Acute- and chronic-phase chronic myelogenous leukemia colony-forming units are highly sensitive to the growth inhibitory effects of c-myb antisense oligodeoxynucleotides. Blood 1992;79:1956-61.
    • (1992) Blood , vol.79 , pp. 1956-1961
    • Ratajczak, M.Z.1    Hijiya, N.2    Catani, L.3
  • 48
    • 0027389763 scopus 로고
    • Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line
    • Miyashita T, Reed JC. Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line. Blood 1993;81:151-7.
    • (1993) Blood , vol.81 , pp. 151-157
    • Miyashita, T.1    Reed, J.C.2
  • 49
    • 0028066802 scopus 로고
    • Antisense oligonucleotides suppress B-cell lymphoma growth in a SCID-hu mouse model
    • Cotter FE, Johnson P, Hal, P, et al. Antisense oligonucleotides suppress B-cell lymphoma growth in a SCID-hu mouse model. Oncogene 1994;9:3049-55.
    • (1994) Oncogene , vol.9 , pp. 3049-3055
    • Cotter, F.E.1    Johnson, P.2    Hal, P.3
  • 50
    • 0031907428 scopus 로고    scopus 로고
    • bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice
    • Jansen B, Schlagbauer-Wadl H, Brown BD, et al. bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice. Nat Med 1998;4:232-4.
    • (1998) Nat Med , vol.4 , pp. 232-234
    • Jansen, B.1    Schlagbauer-Wadl, H.2    Brown, B.D.3
  • 51
    • 0034684471 scopus 로고    scopus 로고
    • Chemosensitisation of malignant melanoma by BCL2 antisense therapy
    • Jansen B, Wacheck V, Heere-Ress E, et al. Chemosensitisation of malignant melanoma by BCL2 antisense therapy. Lancet 2000;356:1728-33.
    • (2000) Lancet , vol.356 , pp. 1728-1733
    • Jansen, B.1    Wacheck, V.2    Heere-Ress, E.3
  • 52
    • 0035871490 scopus 로고    scopus 로고
    • Results of a pilot study involving the use of an antisense oligodeoxynucleotide directed against the insulin-like growth factor type I receptor in malignant astrocytomas
    • Andrews DW, Resnicoff M, Flanders AE, et al. Results of a pilot study involving the use of an antisense oligodeoxynucleotide directed against the insulin-like growth factor type I receptor in malignant astrocytomas. J Clin Oncol 2001;19:2189-200.
    • (2001) J Clin Oncol , vol.19 , pp. 2189-2200
    • Andrews, D.W.1    Resnicoff, M.2    Flanders, A.E.3
  • 53
    • 0034098238 scopus 로고    scopus 로고
    • Evaluating the mechanism of action of antiproliferative antisense drugs
    • Crooke ST. Evaluating the mechanism of action of antiproliferative antisense drugs. Antisense Nucleic Acid Drug Dev 2000;10:123-7.
    • (2000) Antisense Nucleic Acid Drug Dev , vol.10 , pp. 123-127
    • Crooke, S.T.1
  • 54
    • 0037143011 scopus 로고    scopus 로고
    • Postexposure prophylaxis against prian disease with a stimulator of innate immunity
    • Sethi S, Lipford G, Wagner H, et al. Postexposure prophylaxis against prian disease with a stimulator of innate immunity. Lancet 2002;360:229-30.
    • (2002) Lancet , vol.360 , pp. 229-230
    • Sethi, S.1    Lipford, G.2    Wagner, H.3
  • 55
    • 0028278220 scopus 로고
    • Making sense out of anti-sense: Challenges of imaging gene translation with radiolabeled oligonucleotides
    • Piwnica Worms D. Making sense out of anti-sense: challenges of imaging gene translation with radiolabeled oligonucleotides. J Nucl Med 1994;35:1064-6.
    • (1994) J Nucl Med , vol.35 , pp. 1064-1066
    • Piwnica Worms, D.1
  • 56
    • 0032998423 scopus 로고    scopus 로고
    • Keeping the biotechnology of antisense in context
    • Stein CA. Keeping the biotechnology of antisense in context. Nature Biotech 1999;17:209.
    • (1999) Nature Biotech , vol.17 , pp. 209
    • Stein, C.A.1
  • 57
    • 0025169744 scopus 로고
    • Quantitative study of tyrosine hydroxylase mRNA in catecholaminergic neurons and adrenals during develoipment and aging
    • Kedzierski W, Porter JC. Quantitative study of tyrosine hydroxylase mRNA in catecholaminergic neurons and adrenals during develoipment and aging. Mol Brain Res 1990;7:45-51.
    • (1990) Mol Brain Res , vol.7 , pp. 45-51
    • Kedzierski, W.1    Porter, J.C.2
  • 58
    • 0029086725 scopus 로고
    • Characterization of binding sites, extent of binding, and drug interactions of oligonucleotides with albumin
    • Srinivasan SK, Tewary HK, Iversen PL. Characterization of binding sites, extent of binding, and drug interactions of oligonucleotides with albumin. Antisense Res Dev 1995;5:131-9.
    • (1995) Antisense Res Dev , vol.5 , pp. 131-139
    • Srinivasan, S.K.1    Tewary, H.K.2    Iversen, P.L.3
  • 59
    • 0028845327 scopus 로고
    • Binding of phosphorothioate oligodeoxynucleotides to basic fibroblast growth factor, recombinant soluble CD4, laminin and fibronectin is P- chirality independent
    • Benimetskaya L, Tonkinson JL, Koziolkiewicz M, et al. Binding of phosphorothioate oligodeoxynucleotides to basic fibroblast growth factor, recombinant soluble CD4, laminin and fibronectin is P- chirality independent. Nucleic Acids Res 1995;23:4239-45.
    • (1995) Nucleic Acids Res , vol.23 , pp. 4239-4245
    • Benimetskaya, L.1    Tonkinson, J.L.2    Koziolkiewicz, M.3
  • 60
    • 0029828410 scopus 로고    scopus 로고
    • Interaction of oligodeoxynucleotides with mammalian cells
    • Hawley P, Gibson I. Interaction of oligodeoxynucleotides with mammalian cells. Antisense Nucleic Acid Drug Dev 1996;6:185-95.
    • (1996) Antisense Nucleic Acid Drug Dev , vol.6 , pp. 185-195
    • Hawley, P.1    Gibson, I.2
  • 61
    • 0030829919 scopus 로고    scopus 로고
    • Inhibition of coagulation by a phosphorothioate oligonucleotide
    • Henry SP, Novotny W, Leeds J, et al. Inhibition of coagulation by a phosphorothioate oligonucleotide. Antisense Nucleic Acid Drug Dev 1997;7:503-10.
    • (1997) Antisense Nucleic Acid Drug Dev , vol.7 , pp. 503-510
    • Henry, S.P.1    Novotny, W.2    Leeds, J.3
  • 62
    • 0000407290 scopus 로고
    • Mechanism of oligonucleotide uptake by cells: Involvement of specific receptors?
    • Yakubov LA, Deeva EA, Zarytova VF, et al. Mechanism of oligonucleotide uptake by cells: involvement of specific receptors? Proc Natl Acad Sci USA 1989;86:6454-8.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 6454-6458
    • Yakubov, L.A.1    Deeva, E.A.2    Zarytova, V.F.3
  • 63
    • 0026839585 scopus 로고
    • Analysis of oligonucleotide binding, internalization, and intracellular trafficking utilizing a novel radiolabeled crosslinker
    • Geselowitz DA, Neckers LM. Analysis of oligonucleotide binding, internalization, and intracellular trafficking utilizing a novel radiolabeled crosslinker. Antisense Res Dev 1992;2:17-25.
    • (1992) Antisense Res Dev , vol.2 , pp. 17-25
    • Geselowitz, D.A.1    Neckers, L.M.2
  • 64
    • 0028864495 scopus 로고
    • Bovine serum albumin is a major oligonucleotide-binding protein found on the surface of cultured cells
    • Geselowitz DA, Neckers LM. Bovine serum albumin is a major oligonucleotide-binding protein found on the surface of cultured cells. Antisense Res Dev 1995;5:213-17.
    • (1995) Antisense Res Dev , vol.5 , pp. 213-217
    • Geselowitz, D.A.1    Neckers, L.M.2
  • 65
    • 0029086725 scopus 로고
    • Characterization of binding sites, extent of binding, and drug interactions of oligonucleotides with albumin
    • Srinivasan SK, Tewary HK, Iversen PL. Characterization of binding sites, extent of binding, and drug interactions of oligonucleotides with albumin. Antisense Res Dev 1995;5:131-9.
    • (1995) Antisense Res Dev , vol.5 , pp. 131-139
    • Srinivasan, S.K.1    Tewary, H.K.2    Iversen, P.L.3
  • 66
    • 0031984072 scopus 로고    scopus 로고
    • Trojan peptides: The penetratin system for intracellular delivery
    • Derossi D, Chassaing G, Prochiantz A. Trojan peptides: the penetratin system for intracellular delivery. Trends Cell Biol 1998;8:84-7.
    • (1998) Trends Cell Biol , vol.8 , pp. 84-87
    • Derossi, D.1    Chassaing, G.2    Prochiantz, A.3
  • 67
    • 0029943679 scopus 로고    scopus 로고
    • Phosphorothioate antisense oligodeoxynudeotides: Questions of specificity
    • Stein CA. Phosphorothioate antisense oligodeoxynudeotides: questions of specificity. Trends Biotechnol 1996;14:147-9.
    • (1996) Trends Biotechnol , vol.14 , pp. 147-149
    • Stein, C.A.1
  • 68
    • 0031722289 scopus 로고    scopus 로고
    • Peptide nucleic acid smugglers
    • Prochiantz A. Peptide nucleic acid smugglers. Nat Biotechnol 1998;16:819-20.
    • (1998) Nat Biotechnol , vol.16 , pp. 819-820
    • Prochiantz, A.1
  • 69
    • 0030977573 scopus 로고    scopus 로고
    • Nomenclature for synthetic gene delivery systems
    • Feigner PL, Barenholz Y, Behr JP, et al. Nomenclature for synthetic gene delivery systems. Hum Gene Ther 1997;8:511-12.
    • (1997) Hum Gene Ther , vol.8 , pp. 511-512
    • Feigner, P.L.1    Barenholz, Y.2    Behr, J.P.3
  • 70
    • 0031589547 scopus 로고    scopus 로고
    • Enhanced antisense inhibition of human immunodeficiency virus type 1 in cell cultures by DLS delivery system
    • Lavigne C, Thierry AR. Enhanced antisense inhibition of human immunodeficiency virus type 1 in cell cultures by DLS delivery system. Biochem Biophys Res Commun 1997;237:566-71.
    • (1997) Biochem Biophys Res Commun , vol.237 , pp. 566-571
    • Lavigne, C.1    Thierry, A.R.2
  • 71
    • 0036112087 scopus 로고    scopus 로고
    • Characterization of a synthetic anionic vector for oligonudeotide delivery using in vivo whole body dynamic imaging
    • Tavitian B, Marzabal S, Boutet V, et al. Characterization of a synthetic anionic vector for oligonudeotide delivery using in vivo whole body dynamic imaging. Pharm Res 2002;19:367-76.
    • (2002) Pharm Res , vol.19 , pp. 367-376
    • Tavitian, B.1    Marzabal, S.2    Boutet, V.3
  • 72
    • 0031102380 scopus 로고    scopus 로고
    • Nucleic acid selection and the challenge of combinatorial chemistry
    • Osborne SE, Ellington AD. Nucleic acid selection and the challenge of combinatorial chemistry. Chem Rev 1997;97:349-70.
    • (1997) Chem Rev , vol.97 , pp. 349-370
    • Osborne, S.E.1    Ellington, A.D.2
  • 73
    • 0031151974 scopus 로고    scopus 로고
    • The joys of in vitro selection: Chemically dressing oligonucleotides to satiate protein targets
    • Eaton BE. The joys of in vitro selection: chemically dressing oligonucleotides to satiate protein targets. Curr Opin Chem Biol 1997;1:10-16.
    • (1997) Curr Opin Chem Biol , vol.1 , pp. 10-16
    • Eaton, B.E.1
  • 74
    • 0032853242 scopus 로고    scopus 로고
    • In vitro selection of functional nucleic acids
    • Wilson DS, Szostak JW. In vitro selection of functional nucleic acids. Annu Rev Biochem 1999;68:611-47.
    • (1999) Annu Rev Biochem , vol.68 , pp. 611-647
    • Wilson, D.S.1    Szostak, J.W.2
  • 75
    • 0005620475 scopus 로고    scopus 로고
    • Aptamers as therapeutic and diagnostic agents
    • Brody EN, Gold, L. Aptamers as therapeutic and diagnostic agents. J Biotechnol 2000;74:5-13.
    • (2000) J Biotechnol , vol.74 , pp. 5-13
    • Brody, E.N.1    Gold, L.2
  • 76
    • 0002414180 scopus 로고    scopus 로고
    • In vitro selection of nucleic acids for diagnostic applications
    • Hesselberth J, Robertson MP, Jhaveri S, et al. In vitro selection of nucleic acids for diagnostic applications. J Biotechnol 2000;74:15-25.
    • (2000) J Biotechnol , vol.74 , pp. 15-25
    • Hesselberth, J.1    Robertson, M.P.2    Jhaveri, S.3
  • 78
    • 0033790673 scopus 로고    scopus 로고
    • Escort aptamers: A delivery service for diagnosis and therapy
    • Hicke BJ, Stephens AW. Escort aptamers: a delivery service for diagnosis and therapy. J Clin Invest 2000;106:923-8.
    • (2000) J Clin Invest , vol.106 , pp. 923-928
    • Hicke, B.J.1    Stephens, A.W.2
  • 79
    • 0035844150 scopus 로고    scopus 로고
    • Systematic evolution of a DNA aptamer binding to rat brain tumor microvessels, selective targeting of endothelial regulatory protein pigpen
    • Blank M, Weinschenk T, Priemer M, et al. Systematic evolution of a DNA aptamer binding to rat brain tumor microvessels, selective targeting of endothelial regulatory protein pigpen. J Biol Chem 2001;276:16464-8.
    • (2001) J Biol Chem , vol.276 , pp. 16464-16468
    • Blank, M.1    Weinschenk, T.2    Priemer, M.3
  • 80
    • 0033692912 scopus 로고    scopus 로고
    • Nuclease-resistant synthetic ribozymes: Developing a new class of therapeutics
    • Usman N, Blatt LM. Nuclease-resistant synthetic ribozymes: developing a new class of therapeutics. J Clin Invest 2000;106:1197-202.
    • (2000) J Clin Invest , vol.106 , pp. 1197-1202
    • Usman, N.1    Blatt, L.M.2
  • 81
    • 0026802348 scopus 로고
    • 2′-Fluoro- and 2′-amino-2′-deoxynucleoside 5′-triphosphates as substrates for T7 RNA polymerase
    • Aurup H, Williams DM, Eckstein F. 2′-Fluoro- and 2′-amino-2′-deoxynucleoside 5′-triphosphates as substrates for T7 RNA polymerase. Biochemistry 1992;31:9636-41.
    • (1992) Biochemistry , vol.31 , pp. 9636-9641
    • Aurup, H.1    Williams, D.M.2    Eckstein, F.3
  • 82
    • 0032493654 scopus 로고    scopus 로고
    • 2′-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain
    • Ruckman J, Green LS, Beeson J, et al. 2′-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain. J Biol Chem 1998;273:2055-67.
    • (1998) J Biol Chem , vol.273 , pp. 2055-2067
    • Ruckman, J.1    Green, L.S.2    Beeson, J.3
  • 83
    • 0037173068 scopus 로고    scopus 로고
    • In vivo properties of an anti-GnRH Spiegelmer: An example of an oligonucleotide-based therapeutic substance class
    • Wlotzka B, Leva S, Eschgfaller B, et al. In vivo properties of an anti-GnRH Spiegelmer: an example of an oligonucleotide-based therapeutic substance class. Proc Natl Acad Sci USA 2002;99:8898-902.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8898-8902
    • Wlotzka, B.1    Leva, S.2    Eschgfaller, B.3
  • 84
    • 0028869690 scopus 로고
    • Diversity of oligonucleotide functions
    • Gold L, Polisky B, Uhlenbeck O, et al. Diversity of oligonucleotide functions. Ann Rev Biochem 1995;64:763-97.
    • (1995) Ann Rev Biochem , vol.64 , pp. 763-797
    • Gold, L.1    Polisky, B.2    Uhlenbeck, O.3
  • 85
    • 0031152065 scopus 로고    scopus 로고
    • Aptamers as therapeutic and diagnostic reagents: Problems and prospects
    • Osborne SE, Matsumura I, Ellington AD. Aptamers as therapeutic and diagnostic reagents: problems and prospects. Curr Opin Chem Biol 1997;1:5-9.
    • (1997) Curr Opin Chem Biol , vol.1 , pp. 5-9
    • Osborne, S.E.1    Matsumura, I.2    Ellington, A.D.3
  • 86
    • 0032860385 scopus 로고    scopus 로고
    • Aptamers: An emerging class of molecules that rival antibodies in diagnostics
    • Jayasena SD. Aptamers: an emerging class of molecules that rival antibodies in diagnostics. Clin Chem 1999;45:1628-50.
    • (1999) Clin Chem , vol.45 , pp. 1628-1650
    • Jayasena, S.D.1
  • 87
    • 0032087815 scopus 로고    scopus 로고
    • Oligonucleotide libraries-variatio delectat
    • Famulok M, Jenne A. Oligonucleotide libraries-variatio delectat. Curr Opin Chem Biol 1998;2:320-7.
    • (1998) Curr Opin Chem Biol , vol.2 , pp. 320-327
    • Famulok, M.1    Jenne, A.2
  • 88
    • 0029031094 scopus 로고
    • Oligonucleotides as research, diagnostic, and therapeutic agents
    • Gold L. Oligonucleotides as research, diagnostic, and therapeutic agents. J Biol Chem 1995;270:13581-4.
    • (1995) J Biol Chem , vol.270 , pp. 13581-13584
    • Gold, L.1
  • 90
    • 0028609357 scopus 로고
    • Isozyme-specific inhibition of protein kinase C by RNA aptamers
    • Conrad R, Keranen LM, Ellington AD, et al. Isozyme-specific inhibition of protein kinase C by RNA aptamers. J Biol Chem 1994;269:32051-4.
    • (1994) J Biol Chem , vol.269 , pp. 32051-32054
    • Conrad, R.1    Keranen, L.M.2    Ellington, A.D.3
  • 91
    • 0036163867 scopus 로고    scopus 로고
    • Anti-(Raft-1) RNA aptamers that inhibit Ras-induced Raft-1 activation
    • Kimoto M, Shirouzu M, Mizutani S, et al. Anti-(Raft-1) RNA aptamers that inhibit Ras-induced Raft-1 activation. Eur J Biochem 2002;269:697-704.
    • (2002) Eur J Biochem , vol.269 , pp. 697-704
    • Kimoto, M.1    Shirouzu, M.2    Mizutani, S.3
  • 92
    • 0035371796 scopus 로고    scopus 로고
    • Specific oligobodies against ERK-2 that recognize both the native and the denatured state of the protein
    • Bianchini M, Radrizzani M, Brocardo MG, et al. Specific oligobodies against ERK-2 that recognize both the native and the denatured state of the protein. J Immunol Methods 2001;252:191-7.
    • (2001) J Immunol Methods , vol.252 , pp. 191-197
    • Bianchini, M.1    Radrizzani, M.2    Brocardo, M.G.3
  • 93
    • 0032539924 scopus 로고    scopus 로고
    • High affinity ligands from in vitro selection: Complex targets
    • Morris KN, Jensen KB, Julin CM, et al. High affinity ligands from in vitro selection: complex targets. Proc Natl Acad Sci USA 1998;95:2902-7.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2902-2907
    • Morris, K.N.1    Jensen, K.B.2    Julin, C.M.3
  • 94
    • 0035966106 scopus 로고    scopus 로고
    • Tenascin-C aptamers are generated using tumor cells and purified protein
    • Hicke BJ, Marion C, Chang YF, et al. Tenascin-C aptamers are generated using tumor cells and purified protein. J Biol Chem 2001;276:48644-54.
    • (2001) J Biol Chem , vol.276 , pp. 48644-48654
    • Hicke, B.J.1    Marion, C.2    Chang, Y.F.3
  • 95
    • 0032896149 scopus 로고    scopus 로고
    • Novel approach to specific growth factor inhibition in vivo: Antagonism of platelet-derived growth factor in glomerulonephritis by aptamers
    • Floege J, Ostendorf T, Janssen U, et al. Novel approach to specific growth factor inhibition in vivo: antagonism of platelet-derived growth factor in glomerulonephritis by aptamers. Am J Pathol 1999;154:169-79.
    • (1999) Am J Pathol , vol.154 , pp. 169-179
    • Floege, J.1    Ostendorf, T.2    Janssen, U.3
  • 96
    • 0028941645 scopus 로고
    • Selection of an RNA molecule that mimics a major autoantigenic epitope of human insulin receptor
    • Doudna JA, Cech TR, Sullenger BA. Selection of an RNA molecule that mimics a major autoantigenic epitope of human insulin receptor. Proc Natl Acad Sci USA 1995;92:2355-9.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 2355-2359
    • Doudna, J.A.1    Cech, T.R.2    Sullenger, B.A.3
  • 97
    • 0035034653 scopus 로고    scopus 로고
    • Specific antagonism of PDGF prevents renal scarring in experimental glomerulonephritis
    • Ostendorf T, Kunter U, Grone HJ, et al. Specific antagonism of PDGF prevents renal scarring in experimental glomerulonephritis. J Am Soc Nephrol 2001;12:909-18.
    • (2001) J Am Soc Nephrol , vol.12 , pp. 909-918
    • Ostendorf, T.1    Kunter, U.2    Grone, H.J.3
  • 98
    • 0035297541 scopus 로고    scopus 로고
    • Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors
    • Pietras K, Ostman A, Sjoquist M, et al. Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors. Cancer Res 2001;61:2929-34.
    • (2001) Cancer Res , vol.61 , pp. 2929-2934
    • Pietras, K.1    Ostman, A.2    Sjoquist, M.3
  • 99
    • 0027389763 scopus 로고
    • Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line
    • Miyashita T, Reed JC. Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line. Blood 1993;81:151-7.
    • (1993) Blood , vol.81 , pp. 151-157
    • Miyashita, T.1    Reed, J.C.2
  • 100
    • 0034095222 scopus 로고    scopus 로고
    • Technology evaluation: SELEX, Gilead Sciences Inc.
    • Sun S. Technology evaluation: SELEX, Gilead Sciences Inc. Curr Opin Mol Ther 2000;2:100-5.
    • (2000) Curr Opin Mol Ther , vol.2 , pp. 100-105
    • Sun, S.1
  • 101
    • 0031279943 scopus 로고    scopus 로고
    • In vivo imaging of inflammation using an aptamer inhibitor of human neutrophil elastase
    • Charlton J, Sennello J, Smith D. In vivo imaging of inflammation using an aptamer inhibitor of human neutrophil elastase. Chem Biol 1997;4:809-16.
    • (1997) Chem Biol , vol.4 , pp. 809-816
    • Charlton, J.1    Sennello, J.2    Smith, D.3
  • 102
    • 0032170107 scopus 로고    scopus 로고
    • Liposome-anchored vascular endothelial growth factor aptamers
    • Willis MC, Collins BD, Zhang T, et al. Liposome-anchored vascular endothelial growth factor aptamers. Bioconjug Chem 1998;9:573-82.
    • (1998) Bioconjug Chem , vol.9 , pp. 573-582
    • Willis, M.C.1    Collins, B.D.2    Zhang, T.3
  • 103
    • 0026349087 scopus 로고
    • The anti-gene strategy: Control of gene expression by triplex-forming-oligonucleotides
    • Hélène C. The anti-gene strategy: control of gene expression by triplex-forming-oligonucleotides. Anticancer Drug Res 1991;6:569-84.
    • (1991) Anticancer Drug Res , vol.6 , pp. 569-584
    • Hélène, C.1
  • 104
    • 0033792956 scopus 로고    scopus 로고
    • Development of DNA-based radiopharmaceuticals carrying Auger-electron emitters for anti-gene radiotherapy
    • Panyutin IG, Winters TA, Feinendegen LE, et al. Development of DNA-based radiopharmaceuticals carrying Auger-electron emitters for anti-gene radiotherapy. Q J Nucl Med 2000;44:256-67.
    • (2000) Q J Nucl Med , vol.44 , pp. 256-267
    • Panyutin, I.G.1    Winters, T.A.2    Feinendegen, L.E.3
  • 105
    • 0036236762 scopus 로고    scopus 로고
    • Sequence-specific gene cleavage in intact mammalian cells by 1251-labeled triplex-forming oligonudeotides conjugated with nuclear localization signal peptide
    • Sedelnikova OA, Karamychev VN, Panyutin IG, et al. Sequence-specific gene cleavage in intact mammalian cells by 1251-labeled triplex-forming oligonudeotides conjugated with nuclear localization signal peptide. Antisense Nucleic Acid Drug Dev 2002;12:43-9.
    • (2002) Antisense Nucleic Acid Drug Dev , vol.12 , pp. 43-49
    • Sedelnikova, O.A.1    Karamychev, V.N.2    Panyutin, I.G.3
  • 106
    • 0035795428 scopus 로고    scopus 로고
    • RNA interference and small interfering RNAs
    • Tuschl T. RNA interference and small interfering RNAs. Chembiochem 2001;2:239-45
    • (2001) Chembiochem , vol.2 , pp. 239-245
    • Tuschl, T.1
  • 107
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • Elbashir SM, Lendeckel W, Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev 2001;15:188-200.
    • (2001) Genes Dev , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 108
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir SM, Harborth J, Lendeckel W, et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001;411:494-8.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3
  • 109
    • 0036256430 scopus 로고    scopus 로고
    • Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells
    • Lee NS, Dohjima T, Bauer G, et al. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat Biotechnol 2002;20:500-5.
    • (2002) Nat Biotechnol , vol.20 , pp. 500-505
    • Lee, N.S.1    Dohjima, T.2    Bauer, G.3
  • 110
    • 0036251639 scopus 로고    scopus 로고
    • Effective expression of small interfering RNA in human cells
    • Paul CP, Good PD, Winer I, et al. Effective expression of small interfering RNA in human cells. Nat Biotechnol 2002;20:505-8.
    • (2002) Nat Biotechnol , vol.20 , pp. 505-508
    • Paul, C.P.1    Good, P.D.2    Winer, I.3
  • 111
    • 0037019339 scopus 로고    scopus 로고
    • RNA interference in adult mice
    • McCaffrey AP, Meuse L, Pham TT, et al. RNA interference in adult mice. Nature 2002;418:38-9.
    • (2002) Nature , vol.418 , pp. 38-39
    • McCaffrey, A.P.1    Meuse, L.2    Pham, T.T.3
  • 112
    • 0036727416 scopus 로고    scopus 로고
    • Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
    • Lewis DL, Hagstrom JE, Loomis AG, et al. Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat Genet 2002;32:107-8.
    • (2002) Nat Genet , vol.32 , pp. 107-108
    • Lewis, D.L.1    Hagstrom, J.E.2    Loomis, A.G.3


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