Cleavage of notch1 by granzyme B disables its transcriptional activity

Biochemical Journal

Volumn 437, Issue 2, 2011, Pages 313-322

  Van Tetering, Geert ^a   Bovenschen, Niels ^a   Meeldijk, Jan ^a   Van Diest, Paul J ^a   Vooijs, Marc ^a,b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

secretase; Cleavage; Granzyme B; Notch signalling; Proteolysis; Serine protease

Indexed keywords

ASPARTIC ACID; CASPASE; GAMMA SECRETASE; GRANZYME B; NOTCH1 RECEPTOR; PERFORIN;

APOPTOSIS; ARTICLE; CELL DEATH; CELL MATURATION; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; GENETIC TRANSCRIPTION; INTRACELLULAR SPACE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN FUNCTION;

AMYLOID PRECURSOR PROTEIN SECRETASES; APOPTOSIS; CASPASES; CELL DEATH; GRANZYMES; HELA CELLS; HUMANS; RECEPTOR, NOTCH1; TRANSCRIPTIONAL ACTIVATION;

EID: 79959703676     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20110226     Document Type: Article

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