Cell binding, internalization and cytotoxic activity of human granzyme B expressed in the yeast Pichia pastoris

Biochemical Journal

Volumn 394, Issue 3, 2006, Pages 563-573

  Giesübel, Ulrike ^a   Dälken, Benjamin ^a   Mahmud, Hayat ^a   Wels, Winfried S ^a  

^a INSTITUTE FOR TUMOR BIOLOGY AND EXPERIMENTAL THERAPY   (Germany)

Author keywords

Apoptosis; Cellular uptake; Extracellular matrix; Granzyme B; Pichia pastoris; Procaspase 3

Indexed keywords

LIPIDS; MORPHOLOGY; POSITIVE IONS; PROTEINS; TOXICITY; YEAST;

APOPTOSIS; CELLULAR UPTAKE; EXTRACELLULAR MATRIX; GRANZYME B; PICHIA PASTORIS; PROCASPASE 3;

CELLS;

CHLOROQUINE; GRANZYME B; RECOMBINANT ENZYME;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING AFFINITY; CELL STRUCTURE; CELL TRANSPORT; CONTROLLED STUDY; CYTOTOXICITY; DRUG INHIBITION; ENDOSOME; ENZYME ACTIVITY; HELA CELL; HUMAN; HUMAN CELL; LYSOSOME; NONHUMAN; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR CELL; YEAST;

ANILIDES; APOPTOSIS; CELL LINE, TUMOR; ENDOCYTOSIS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GRANZYMES; HUMANS; HYDROLYSIS; KINETICS; OLIGOPEPTIDES; PICHIA; PROTEIN BINDING; PROTEIN TRANSPORT; RECOMBINANT PROTEINS; SERINE ENDOPEPTIDASES;

ANIMALIA; PICHIA PASTORIS;

EID: 33644997146     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20050687     Document Type: Article

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