-
1
-
-
0028294895
-
The binding and lysis of target cells by cytotoxic lymphocytes: Molecular and cellular aspects
-
Berke G (1994) The binding and lysis of target cells by cytotoxic lymphocytes: molecular and cellular aspects. Annu. Rev. Immunol. 12: 735-773
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 735-773
-
-
Berke, G.1
-
2
-
-
0028932731
-
The CTL's kiss of death
-
Berke G (1995) The CTL's kiss of death. Cell 81: 9-12
-
(1995)
Cell
, vol.81
, pp. 9-12
-
-
Berke, G.1
-
3
-
-
0031393753
-
Proteases and cell-mediated cytotoxicity
-
Darmon AJ and Bleackley RC (1998) Proteases and cell-mediated cytotoxicity. Crit. Rev. Immunol. 18: 255-273
-
(1998)
Crit. Rev. Immunol.
, vol.18
, pp. 255-273
-
-
Darmon, A.J.1
Bleackley, R.C.2
-
5
-
-
0032147225
-
Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis
-
Pinkoski MJ, Hobman M, Heibein JA, Tomaselli K, Li F, Seth P, Froelich CJ and Bleackley RC (1998) Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis. Blood 92: 1044-1054
-
(1998)
Blood
, vol.92
, pp. 1044-1054
-
-
Pinkoski, M.J.1
Hobman, M.2
Heibein, J.A.3
Tomaselli, K.4
Li, F.5
Seth, P.6
Froelich, C.J.7
Bleackley, R.C.8
-
6
-
-
0030892138
-
Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization
-
Shi L, Mai S, Israels S, Browne K, Trapani JA and Greenberg AH (1997) Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization. J Exp Med 185: 855-866
-
(1997)
J Exp Med
, vol.185
, pp. 855-866
-
-
Shi, L.1
Mai, S.2
Israels, S.3
Browne, K.4
Trapani, J.A.5
Greenberg, A.H.6
-
7
-
-
0030006046
-
Binding of granzyme B in the nucleus of target cells. Recognition of an 80-kilodalton protein
-
Pinkoski MJ, Winkler U, Hudig D and Bleackley RC (1996) Binding of granzyme B in the nucleus of target cells. Recognition of an 80-kilodalton protein. J Biol Chem 271: 10225-10229
-
(1996)
J Biol Chem
, vol.271
, pp. 10225-10229
-
-
Pinkoski, M.J.1
Winkler, U.2
Hudig, D.3
Bleackley, R.C.4
-
8
-
-
0030044052
-
Localization of granzyme B in the nucleus. A putative role in the mechanism of cytotoxic lymphocyte-mediated apoptosis
-
Trapani JA, Browne KA, Smyth MJ and Jans DA (1996) Localization of granzyme B in the nucleus. A putative role in the mechanism of cytotoxic lymphocyte-mediated apoptosis. J. Biol. Chem. 271: 4127-4133
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 4127-4133
-
-
Trapani, J.A.1
Browne, K.A.2
Smyth, M.J.3
Jans, D.A.4
-
9
-
-
0031847334
-
Perforin-dependent nuclear entry of granzyme B precedes apoptosis, and is not a consequence of nuclear membrane dysfunction
-
Trapani JA, Jans P, Smyth MJ, Froelich CJ, Williams EA, Sutton VR and Jans DA (1998) Perforin-dependent nuclear entry of granzyme B precedes apoptosis, and is not a consequence of nuclear membrane dysfunction. Cell Death Differ. 5: 488-496
-
(1998)
Cell Death Differ.
, vol.5
, pp. 488-496
-
-
Trapani, J.A.1
Jans, P.2
Smyth, M.J.3
Froelich, C.J.4
Williams, E.A.5
Sutton, V.R.6
Jans, D.A.7
-
10
-
-
0032561352
-
Efficient nuclear targeting of granzyme B and the nuclear consequences of apoptosis induced by granzyme B and perforin are caspase-dependent, but cell death is caspase-independent
-
Trapani JA, Jans DA, Jans PJ, Smyth MJ, Browne KA and Sutton VR (1998) Efficient nuclear targeting of granzyme B and the nuclear consequences of apoptosis induced by granzyme B and perforin are caspase-dependent, but cell death is caspase-independent. J Biol Chem 273: 27934-27938
-
(1998)
J Biol Chem
, vol.273
, pp. 27934-27938
-
-
Trapani, J.A.1
Jans, D.A.2
Jans, P.J.3
Smyth, M.J.4
Browne, K.A.5
Sutton, V.R.6
-
11
-
-
0028990681
-
Nuclear changes in the cytotoxic T lymphocyte-induced model of apoptosis
-
Sellins KS and Cohen JJ (1995) Nuclear changes in the cytotoxic T lymphocyte-induced model of apoptosis. Immunol. Rev. 146: 241-266
-
(1995)
Immunol. Rev.
, vol.146
, pp. 241-266
-
-
Sellins, K.S.1
Cohen, J.J.2
-
12
-
-
0018830636
-
Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
-
Wyllie AH (1980) Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284: 555-556.
-
(1980)
Nature
, vol.284
, pp. 555-556
-
-
Wyllie, A.H.1
-
13
-
-
0021346318
-
Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis
-
Wyllie AH, Morris RG, Smith AL and Dunlop D (1984) Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis. J. Pathol. 142: 67-77
-
(1984)
J. Pathol.
, vol.142
, pp. 67-77
-
-
Wyllie, A.H.1
Morris, R.G.2
Smith, A.L.3
Dunlop, D.4
-
14
-
-
0011123295
-
Endogenous endonuclease-induced DNA fragmentation: An early event in cell-mediated cytolysis
-
Duke RC, Chervenak R and Cohen JJ (1983) Endogenous endonuclease-induced DNA fragmentation: an early event in cell-mediated cytolysis. Proc. Natl. Acad. Sci. USA 80: 6361-6365
-
(1983)
Proc. Natl. Acad. Sci. USA
, vol.80
, pp. 6361-6365
-
-
Duke, R.C.1
Chervenak, R.2
Cohen, J.J.3
-
15
-
-
0025754857
-
Nuclear lamin proteins: Domains required for nuclear targeting, assembly, and cell-cycle-regulated dynamics
-
McKeon F (1991) Nuclear lamin proteins: domains required for nuclear targeting, assembly, and cell-cycle-regulated dynamics. Curr. Opin. Cell Biol. 3: 82-86
-
(1991)
Curr. Opin. Cell Biol.
, vol.3
, pp. 82-86
-
-
McKeon, F.1
-
16
-
-
0029046470
-
Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution
-
Lazebnik YA, Takahashi A, Moir RD, Goldman RD, Poirier GG, Kaufmann SH and Earnshaw WC (1995) Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution. Proc. Natl. Acad. Sci. USA 92: 9042-9046
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9042-9046
-
-
Lazebnik, Y.A.1
Takahashi, A.2
Moir, R.D.3
Goldman, R.D.4
Poirier, G.G.5
Kaufmann, S.H.6
Earnshaw, W.C.7
-
17
-
-
0029758833
-
Cleavage of lamin A by Mch2 alpha but not CPP32: Multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis
-
Takahashi A, Alnemri ES, Lazebnik YA, Fernandes-Alnemri T, Litwack G, Moir RD, Goldman RD, Poirier GG, Kaufmann SH and Earnshaw WC (1996) Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis. Proc. Natl. Acad. Sci. USA 93: 8395-8400
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 8395-8400
-
-
Takahashi, A.1
Alnemri, E.S.2
Lazebnik, Y.A.3
Fernandes-Alnemri, T.4
Litwack, G.5
Moir, R.D.6
Goldman, R.D.7
Poirier, G.G.8
Kaufmann, S.H.9
Earnshaw, W.C.10
-
18
-
-
0031889132
-
Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
-
Sakahira H, Enari M and Nagata S (1998) Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 391: 96-99
-
(1998)
Nature
, vol.391
, pp. 96-99
-
-
Sakahira, H.1
Enari, M.2
Nagata, S.3
-
19
-
-
0030916417
-
DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
-
Liu X, Zou H, Slaughter C and Wang X (1997) DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 89: 175-184
-
(1997)
Cell
, vol.89
, pp. 175-184
-
-
Liu, X.1
Zou, H.2
Slaughter, C.3
Wang, X.4
-
20
-
-
0031888955
-
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
-
Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A and Nagata S (1998) A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 391: 43-50
-
(1998)
Nature
, vol.391
, pp. 43-50
-
-
Enari, M.1
Sakahira, H.2
Yokoyama, H.3
Okawa, K.4
Iwamatsu, A.5
Nagata, S.6
-
21
-
-
0029797971
-
Regulation of protein transport to the nucleus: Central role of phosphorylation
-
Jans DA and Hubner S (1996) Regulation of protein transport to the nucleus: central role of phosphorylation. Physiol. Rev. 76: 651-685
-
(1996)
Physiol. Rev.
, vol.76
, pp. 651-685
-
-
Jans, D.A.1
Hubner, S.2
-
22
-
-
0033548065
-
BCL-2 blocks perforin-induced nuclear translocation of granzymes concomitant with protection against the nuclear events of apoptosis
-
Jans DA, Sutton VR, Jans P, Froelich CJ and Trapani JA (1999) BCL-2 blocks perforin-induced nuclear translocation of granzymes concomitant with protection against the nuclear events of apoptosis. J Biol Chem 274: 3953-3961
-
(1999)
J Biol Chem
, vol.274
, pp. 3953-3961
-
-
Jans, D.A.1
Sutton, V.R.2
Jans, P.3
Froelich, C.J.4
Trapani, J.A.5
-
23
-
-
0031669558
-
Nuclear targeting of the serine protease granzyme A (fragmentin-1)
-
Jans DA, Briggs LJ, Jans P, Froelich CJ, Parasivam G, Kumar S, Sutton VR and Trapani JA (1998) Nuclear targeting of the serine protease granzyme A (fragmentin-1). J. Cell Sci. 111: 2645-2654
-
(1998)
J. Cell Sci.
, vol.111
, pp. 2645-2654
-
-
Jans, D.A.1
Briggs, L.J.2
Jans, P.3
Froelich, C.J.4
Parasivam, G.5
Kumar, S.6
Sutton, V.R.7
Trapani, J.A.8
-
24
-
-
0025774123
-
The function of lymphocyte proteases. Inhibition and restoration of granule-mediated lysis with isocoumarin serine protease inhibitors
-
Hudig D, Allison NJ, Pickett TM, Winkler U, Kam CM and Powers JC (1991) The function of lymphocyte proteases. Inhibition and restoration of granule-mediated lysis with isocoumarin serine protease inhibitors. J. Immunol. 147: 1360-1368
-
(1991)
J. Immunol.
, vol.147
, pp. 1360-1368
-
-
Hudig, D.1
Allison, N.J.2
Pickett, T.M.3
Winkler, U.4
Kam, C.M.5
Powers, J.C.6
-
25
-
-
0029099845
-
Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B
-
Darmon AJ, Nicholson DW and Bleackley RC (1995) Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B. Nature 377: 446-448
-
(1995)
Nature
, vol.377
, pp. 446-448
-
-
Darmon, A.J.1
Nicholson, D.W.2
Bleackley, R.C.3
-
26
-
-
0029832173
-
Cleavage of CPP32 by granzyme B represents a critical role for granzyme B in the induction of target cell DNA fragmentation
-
Darmon AJ, Ley TJ, Nicholson DW and Bleackley RC (1996) Cleavage of CPP32 by granzyme B represents a critical role for granzyme B in the induction of target cell DNA fragmentation. J. Biol. Chem. 271: 21709-21712
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 21709-21712
-
-
Darmon, A.J.1
Ley, T.J.2
Nicholson, D.W.3
Bleackley, R.C.4
-
27
-
-
0029984570
-
Nucleocytoplasmic transport
-
Gorlich D and Mattaj IW (1996) Nucleocytoplasmic transport. Science 271: 1513-1518
-
(1996)
Science
, vol.271
, pp. 1513-1518
-
-
Gorlich, D.1
Mattaj, I.W.2
-
28
-
-
0029060051
-
The nuclear pore complex
-
Davis LI (1995) The nuclear pore complex. Annu. Rev. Biochem. 64: 865-896
-
(1995)
Annu. Rev. Biochem.
, vol.64
, pp. 865-896
-
-
Davis, L.I.1
-
29
-
-
0030964105
-
Nucleocytoplasmic transport: Signals, mechanisms and regulation
-
Nigg EA (1997) Nucleocytoplasmic transport: signals, mechanisms and regulation. Nature 386: 779-787
-
(1997)
Nature
, vol.386
, pp. 779-787
-
-
Nigg, E.A.1
-
30
-
-
0029068871
-
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
-
Nicholson DW, Ali A, Thornberry NA, Vaillancourt JP, Ding CK, Gallant M, Gareau Y, Griffin PR, Labelle M and Lazebnik YA, et al. (1995) Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 376: 37-43
-
(1995)
Nature
, vol.376
, pp. 37-43
-
-
Nicholson, D.W.1
Ali, A.2
Thornberry, N.A.3
Vaillancourt, J.P.4
Ding, C.K.5
Gallant, M.6
Gareau, Y.7
Griffin, P.R.8
Labelle, M.9
Lazebnik, Y.A.10
-
31
-
-
0028990125
-
Yama/CPP32 beta, a mammalian homolog of CED-3. is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
-
Tewari M, Quan LT, O'Rourke K, Desnoyers S, Zeng Z, Beidler DR, Poirier GG, Salvesen GS and Dixit VM (1995) Yama/CPP32 beta, a mammalian homolog of CED-3. is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell 81: 801-809
-
(1995)
Cell
, vol.81
, pp. 801-809
-
-
Tewari, M.1
Quan, L.T.2
O'Rourke, K.3
Desnoyers, S.4
Zeng, Z.5
Beidler, D.R.6
Poirier, G.G.7
Salvesen, G.S.8
Dixit, V.M.9
-
32
-
-
0032541132
-
Detection of pro-caspase-3 in cytosol and mitochondria of various tissues
-
Samali A, Zhivotovsky B, Jones DP and Orrenius S (1998) Detection of pro-caspase-3 in cytosol and mitochondria of various tissues. FEBS Lett. 431: 167-169
-
(1998)
FEBS Lett.
, vol.431
, pp. 167-169
-
-
Samali, A.1
Zhivotovsky, B.2
Jones, D.P.3
Orrenius, S.4
-
33
-
-
0032080004
-
Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver
-
Chandler JM, Cohen GM and MacFarlane M (1998) Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver. J. Biol. Chem. 273: 10815-10818
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 10815-10818
-
-
Chandler, J.M.1
Cohen, G.M.2
MacFarlane, M.3
-
34
-
-
0030198505
-
Cytotoxic T-cell-derived granzyme B activates the apoptotic protease ICE-LAP3
-
Chinnaiyan AM, Hanna WL, Orth K, Duan H, Poirier GG, Froelich CJ and Dixit VM (1996) Cytotoxic T-cell-derived granzyme B activates the apoptotic protease ICE-LAP3. Curr. Biol. 6: 897-899
-
(1996)
Curr. Biol.
, vol.6
, pp. 897-899
-
-
Chinnaiyan, A.M.1
Hanna, W.L.2
Orth, K.3
Duan, H.4
Poirier, G.G.5
Froelich, C.J.6
Dixit, V.M.7
-
35
-
-
0032516917
-
Cytotoxic T lymphocyte-assisted suicide. Caspase 3 activation is primarily the result of the direct action of granzyme
-
Atkinson EA, Barry M, Darmon AJ, Shostak I, Turner PC, Moyer RW and Bleackley RC (1998) Cytotoxic T lymphocyte-assisted suicide. Caspase 3 activation is primarily the result of the direct action of granzyme B. J. Biol. Chem. 273: 21261-21266
-
(1998)
B. J. Biol. Chem.
, vol.273
, pp. 21261-21266
-
-
Atkinson, E.A.1
Barry, M.2
Darmon, A.J.3
Shostak, I.4
Turner, P.C.5
Moyer, R.W.6
Bleackley, R.C.7
-
36
-
-
0033137079
-
Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation
-
Beresford PJ, Zhinan X, Greenberg AH and Lieberman J (1999) Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation. Immunity 10: 585-594
-
(1999)
Immunity
, vol.10
, pp. 585-594
-
-
Beresford, P.J.1
Zhinan, X.2
Greenberg, A.H.3
Lieberman, J.4
-
37
-
-
0032055097
-
Granzyme B directly and efficiently cleaves several downstream caspase substrates: Implications for CTL-induced apoptosis
-
Andrande F, Roy S, Nicholson D, Thornberry N, Rosen A and Casciola-Rosen L (1998) Granzyme B directly and efficiently cleaves several downstream caspase substrates: implications for CTL-induced apoptosis. Immunity 8: 451-460
-
(1998)
Immunity
, vol.8
, pp. 451-460
-
-
Andrande, F.1
Roy, S.2
Nicholson, D.3
Thornberry, N.4
Rosen, A.5
Casciola-Rosen, L.6
-
38
-
-
0029844220
-
Nuclear transport of granzyme B (fragmentin-2). Dependence of perforin in vivo and cytosolic factors in vitro
-
Jans DA, Jans P, Briggs LJ, Sutton V and Trapani JA (1996) Nuclear transport of granzyme B (fragmentin-2). Dependence of perforin in vivo and cytosolic factors in vitro. J. Biol. Chem. 271: 30781-30789
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 30781-30789
-
-
Jans, D.A.1
Jans, P.2
Briggs, L.J.3
Sutton, V.4
Trapani, J.A.5
-
39
-
-
0027169762
-
Activation of recombinant murine cytotoxic cell proteinase-1 requires deletion of an amino-terminal dipeptide
-
Caputo A, Garner RS, Winkler U, Hudig D and Bleackley RC (1993) Activation of recombinant murine cytotoxic cell proteinase-1 requires deletion of an amino-terminal dipeptide. J. Biol. Chem. 268: 17672-17675
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 17672-17675
-
-
Caputo, A.1
Garner, R.S.2
Winkler, U.3
Hudig, D.4
Bleackley, R.C.5
-
40
-
-
0027675416
-
Rapid purification of cationic granule proteases: Application to human granzymes
-
Hanna WL, Zhang X, Turbov J, Winkler U, Hudig D and Froelich CJ (1993) Rapid purification of cationic granule proteases: application to human granzymes. Protein Expr. Purif. 4: 398-404
-
(1993)
Protein Expr. Purif.
, vol.4
, pp. 398-404
-
-
Hanna, W.L.1
Zhang, X.2
Turbov, J.3
Winkler, U.4
Hudig, D.5
Froelich, C.J.6
-
42
-
-
0026648674
-
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
-
Gavrieli Y, Sherman Y and Ben-Sasson SA (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell. Biol. 119: 493-501
-
(1992)
J. Cell. Biol.
, vol.119
, pp. 493-501
-
-
Gavrieli, Y.1
Sherman, Y.2
Ben-Sasson, S.A.3
|