Granzyme B proteolyzes receptors important to proliferation and survival, tipping the balance toward apoptosis

Journal of Biological Chemistry

Volumn 281, Issue 38, 2006, Pages 28326-28335

  Loeb, Carly R K ^a   Harris, Jennifer L ^b,c   Craik, Charles S ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL ENGINEERING; CELLS; DNA; ENZYME KINETICS; GROWTH KINETICS; TUMORS;

APOPTOSIS; CANCER CELLS; CELL DEATH; RIBONUCLEOPROTEIN;

ENZYMES;

CASPASE; COMPLEMENTARY DNA; FIBROBLAST GROWTH FACTOR RECEPTOR 1; GRANZYME B; HEAT SHOCK PROTEIN 70; NOTCH1 RECEPTOR; NUCLEAR RNA; POLYADENYLIC ACID BINDING PROTEIN;

APOPTOSIS; ARTICLE; CANCER CELL; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DEGRADATION;

AMINO ACID SEQUENCE; APOPTOSIS; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; GENE LIBRARY; GRANZYMES; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MALE; MOLECULAR SEQUENCE DATA; PROSTATIC NEOPLASMS; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; RECEPTOR, NOTCH1; SERINE ENDOPEPTIDASES;

EID: 33748779522     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M604544200     Document Type: Article

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