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Volumn 90, Issue 8, 2011, Pages 631-641

P21 Cip1 regulates cell-substrate adhesion and interphase microtubule dynamics in untransformed human mammary epithelial cells

Author keywords

Breast cancer; CDKN1A; Focal adhesion; HDAC6; Mammary epithelial cells; Microtubule; P21 Cip1

Indexed keywords

ALPHA TUBULIN; CYCLIN DEPENDENT KINASE INHIBITOR 1; PROTEIN CDC42; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; TUBACIN;

EID: 79957785372     PISSN: 01719335     EISSN: 16181298     Source Type: Journal    
DOI: 10.1016/j.ejcb.2011.03.002     Document Type: Article
Times cited : (4)

References (95)
  • 1
    • 67649424560 scopus 로고    scopus 로고
    • P21 in cancer: intricate networks and multiple activities
    • Abbas T., Dutta A. p21 in cancer: intricate networks and multiple activities. Nat. Rev. Cancer 2009, 9:400-414.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 400-414
    • Abbas, T.1    Dutta, A.2
  • 3
    • 0033104495 scopus 로고    scopus 로고
    • Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation
    • Asada M., Yamada T., Ichijo H., Delia D., Miyazono K., Fukumuro K., Mizutani S. Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation. EMBO J. 1999, 18:1223-1234.
    • (1999) EMBO J. , vol.18 , pp. 1223-1234
    • Asada, M.1    Yamada, T.2    Ichijo, H.3    Delia, D.4    Miyazono, K.5    Fukumuro, K.6    Mizutani, S.7
  • 4
    • 0029666272 scopus 로고    scopus 로고
    • Functional analysis of a p21WAF1,CIP1 SDI1 mutant (Arg94→Trp) identified in a human breast carcinoma. Evidence that the mutation impairs the ability of p21 to inhibit cyclin-dependent kinases
    • Balbin M., Hannon G.J., Pendas A.M., Ferrando A.A., Vizoso F., Fueyo A., Lopez-Otin C. Functional analysis of a p21WAF1,CIP1 SDI1 mutant (Arg94→Trp) identified in a human breast carcinoma. Evidence that the mutation impairs the ability of p21 to inhibit cyclin-dependent kinases. J. Biol. Chem. 1996, 271:15782-15786.
    • (1996) J. Biol. Chem. , vol.271 , pp. 15782-15786
    • Balbin, M.1    Hannon, G.J.2    Pendas, A.M.3    Ferrando, A.A.4    Vizoso, F.5    Fueyo, A.6    Lopez-Otin, C.7
  • 12
    • 0028899480 scopus 로고
    • Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA
    • Chen J., Jackson P.K., Kirschner M.W., Dutta A. Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA. Nature 1995, 374:386-388.
    • (1995) Nature , vol.374 , pp. 386-388
    • Chen, J.1    Jackson, P.K.2    Kirschner, M.W.3    Dutta, A.4
  • 13
    • 0032489802 scopus 로고    scopus 로고
    • Rho guanosine triphosphatase mediates the selective stabilization of microtubules induced by lysophosphatidic acid
    • Cook T.A., Nagasaki T., Gundersen G.G. Rho guanosine triphosphatase mediates the selective stabilization of microtubules induced by lysophosphatidic acid. J. Cell Biol. 1998, 141:175-185.
    • (1998) J. Cell Biol. , vol.141 , pp. 175-185
    • Cook, T.A.1    Nagasaki, T.2    Gundersen, G.G.3
  • 14
    • 25444443688 scopus 로고    scopus 로고
    • Modelling glandular epithelial cancers in three-dimensional cultures
    • Debnath J., Brugge J.S. Modelling glandular epithelial cancers in three-dimensional cultures. Nat. Rev. Cancer 2005, 5:675-688.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 675-688
    • Debnath, J.1    Brugge, J.S.2
  • 15
    • 0033598444 scopus 로고    scopus 로고
    • Control of E2F activity by p21Waf1/Cip1
    • Delavaine L., La Thangue N.B. Control of E2F activity by p21Waf1/Cip1. Oncogene 1999, 18:5381-5392.
    • (1999) Oncogene , vol.18 , pp. 5381-5392
    • Delavaine, L.1    La Thangue, N.B.2
  • 16
    • 0028978183 scopus 로고
    • Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
    • Deng C., Zhang P., Harper J.W., Elledge S.J., Leder P. Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 1995, 82:675-684.
    • (1995) Cell , vol.82 , pp. 675-684
    • Deng, C.1    Zhang, P.2    Harper, J.W.3    Elledge, S.J.4    Leder, P.5
  • 17
    • 23744515800 scopus 로고    scopus 로고
    • A novel Rho-mDia2-HDAC6 pathway controls podosome patterning through microtubule acetylation in osteoclasts
    • Destaing O., Saltel F., Gilquin B., Chabadel A., Khochbin S., Ory S., Jurdic P. A novel Rho-mDia2-HDAC6 pathway controls podosome patterning through microtubule acetylation in osteoclasts. J. Cell Sci. 2005, 118:2901-2911.
    • (2005) J. Cell Sci. , vol.118 , pp. 2901-2911
    • Destaing, O.1    Saltel, F.2    Gilquin, B.3    Chabadel, A.4    Khochbin, S.5    Ory, S.6    Jurdic, P.7
  • 18
    • 68249125182 scopus 로고    scopus 로고
    • Significance of microtubule catastrophes at focal adhesion sites
    • Efimov A., Kaverina I. Significance of microtubule catastrophes at focal adhesion sites. Cell Adh. Migr. 2009, 3:285-287.
    • (2009) Cell Adh. Migr. , vol.3 , pp. 285-287
    • Efimov, A.1    Kaverina, I.2
  • 21
    • 75749155892 scopus 로고    scopus 로고
    • From signaling pathways to microtubule dynamics: the key players
    • Etienne-Manneville S. From signaling pathways to microtubule dynamics: the key players. Curr. Opin. Cell Biol. 2010, 210:104-111.
    • (2010) Curr. Opin. Cell Biol. , vol.210 , pp. 104-111
    • Etienne-Manneville, S.1
  • 22
    • 0037434790 scopus 로고    scopus 로고
    • Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity
    • Etienne-Manneville S., Hall A. Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity. Nature 2003, 421:753-756.
    • (2003) Nature , vol.421 , pp. 753-756
    • Etienne-Manneville, S.1    Hall, A.2
  • 23
    • 74049160017 scopus 로고    scopus 로고
    • Clathrin mediates integrin endocytosis for focal adhesion disassembly in migrating cells
    • Ezratty E.J., Bertaux C., Marcantonio E.E., Gundersen G.G. Clathrin mediates integrin endocytosis for focal adhesion disassembly in migrating cells. J. Cell Biol. 2009, 187:733-747.
    • (2009) J. Cell Biol. , vol.187 , pp. 733-747
    • Ezratty, E.J.1    Bertaux, C.2    Marcantonio, E.E.3    Gundersen, G.G.4
  • 24
    • 20444370219 scopus 로고    scopus 로고
    • Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase
    • Ezratty E.J., Partridge M.A., Gundersen G.G. Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase. Nat. Cell Biol. 2005, 7:581-590.
    • (2005) Nat. Cell Biol. , vol.7 , pp. 581-590
    • Ezratty, E.J.1    Partridge, M.A.2    Gundersen, G.G.3
  • 25
    • 1642282882 scopus 로고    scopus 로고
    • Prespecification and plasticity: shifting mechanisms of cell migration
    • Friedl P. Prespecification and plasticity: shifting mechanisms of cell migration. Curr. Opin. Cell Biol. 2004, 16:14-23.
    • (2004) Curr. Opin. Cell Biol. , vol.16 , pp. 14-23
    • Friedl, P.1
  • 26
    • 75749146306 scopus 로고    scopus 로고
    • Plasticity of cell migration: a multiscale tuning model
    • Friedl P., Wolf K. Plasticity of cell migration: a multiscale tuning model. J. Cell Biol. 2010, 188:11-19.
    • (2010) J. Cell Biol. , vol.188 , pp. 11-19
    • Friedl, P.1    Wolf, K.2
  • 29
    • 25444490344 scopus 로고    scopus 로고
    • P21WAF1/CIP1 regulates the p300 sumoylation motif CRD1 through a C-terminal domain independently of cyclin/CDK binding
    • Garcia-Wilson E., Perkins N.D. p21WAF1/CIP1 regulates the p300 sumoylation motif CRD1 through a C-terminal domain independently of cyclin/CDK binding. Cell Cycle 2005, 4:1113-1119.
    • (2005) Cell Cycle , vol.4 , pp. 1113-1119
    • Garcia-Wilson, E.1    Perkins, N.D.2
  • 32
    • 0038522853 scopus 로고    scopus 로고
    • Multidimensional chemical genetic analysis of diversity-oriented synthesis-derived deacetylase inhibitors using cell-based assays
    • Haggarty S.J., Koeller K.M., Wong J.C., Butcher R.A., Schreiber S.L. Multidimensional chemical genetic analysis of diversity-oriented synthesis-derived deacetylase inhibitors using cell-based assays. Chem. Biol. 2003, 10:383-396.
    • (2003) Chem. Biol. , vol.10 , pp. 383-396
    • Haggarty, S.J.1    Koeller, K.M.2    Wong, J.C.3    Butcher, R.A.4    Schreiber, S.L.5
  • 34
    • 68549126922 scopus 로고    scopus 로고
    • The cytoskeleton and cancer
    • Hall A. The cytoskeleton and cancer. Cancer Metastasis Rev. 2009, 28:5-14.
    • (2009) Cancer Metastasis Rev. , vol.28 , pp. 5-14
    • Hall, A.1
  • 35
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper J.W., Adami G.R., Wei N., Keyomarsi K., Elledge S.J. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 1993, 75:805-816.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 36
    • 0038094504 scopus 로고    scopus 로고
    • Sustained activation of the JNK cascade and rapamycin-induced apoptosis are suppressed by p53/p21 (Cip1)
    • Huang S., Shu L., Dilling M.B., Easton J., Harwood F.C., Ichijo H., Houghton P.J. Sustained activation of the JNK cascade and rapamycin-induced apoptosis are suppressed by p53/p21 (Cip1). Mol. Cell 2003, 11:1491-1501.
    • (2003) Mol. Cell , vol.11 , pp. 1491-1501
    • Huang, S.1    Shu, L.2    Dilling, M.B.3    Easton, J.4    Harwood, F.C.5    Ichijo, H.6    Houghton, P.J.7
  • 38
    • 66849101632 scopus 로고    scopus 로고
    • Adhesion signaling-crosstalk between integrins, Src and Rho
    • Huveneers S., Danen E.H. Adhesion signaling-crosstalk between integrins, Src and Rho. J. Cell Sci. 2009, 122:1059-1069.
    • (2009) J. Cell Sci. , vol.122 , pp. 1059-1069
    • Huveneers, S.1    Danen, E.H.2
  • 41
    • 0032872870 scopus 로고    scopus 로고
    • Microtubule targeting of substrate contacts promotes their relaxation and dissociation
    • Kaverina I., Krylyshkina O., Small J.V. Microtubule targeting of substrate contacts promotes their relaxation and dissociation. J. Cell Biol. 1999, 146:1033-1044.
    • (1999) J. Cell Biol. , vol.146 , pp. 1033-1044
    • Kaverina, I.1    Krylyshkina, O.2    Small, J.V.3
  • 42
    • 0032514208 scopus 로고    scopus 로고
    • Targeting, capture, and stabilization of microtubules at early focal adhesions
    • Kaverina I., Rottner K., Small J.V. Targeting, capture, and stabilization of microtubules at early focal adhesions. J. Cell Biol. 1998, 142:181-190.
    • (1998) J. Cell Biol. , vol.142 , pp. 181-190
    • Kaverina, I.1    Rottner, K.2    Small, J.V.3
  • 44
    • 0034616116 scopus 로고    scopus 로고
    • Reciprocal regulation via protein-protein interaction between c-Myc and p21(cip1/waf1/sdi1) in DNA replication and transcription
    • Kitaura H., Shinshi M., Uchikoshi Y., Ono T., Iguchi-Ariga S.M., Ariga H. Reciprocal regulation via protein-protein interaction between c-Myc and p21(cip1/waf1/sdi1) in DNA replication and transcription. J. Biol. Chem. 2000, 275:10477-10483.
    • (2000) J. Biol. Chem. , vol.275 , pp. 10477-10483
    • Kitaura, H.1    Shinshi, M.2    Uchikoshi, Y.3    Ono, T.4    Iguchi-Ariga, S.M.5    Ariga, H.6
  • 45
    • 0036228955 scopus 로고    scopus 로고
    • Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton
    • Krendel M., Zenke F.T., Bokoch G.M. Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton. Nat. Cell Biol. 2002, 4:294-301.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 294-301
    • Krendel, M.1    Zenke, F.T.2    Bokoch, G.M.3
  • 46
    • 27744493325 scopus 로고    scopus 로고
    • A microtubule-binding Rho-GEF controls cell morphology during convergent extension of Xenopus laevis
    • Kwan K.M., Kirschner M.W. A microtubule-binding Rho-GEF controls cell morphology during convergent extension of Xenopus laevis. Development 2005, 132:4599-4610.
    • (2005) Development , vol.132 , pp. 4599-4610
    • Kwan, K.M.1    Kirschner, M.W.2
  • 47
    • 0035954424 scopus 로고    scopus 로고
    • Differential dynamics of alpha 5 integrin, paxillin, and alpha-actinin during formation and disassembly of adhesions in migrating cells
    • Laukaitis C.M., Webb D.J., Donais K., Horwitz A.F. Differential dynamics of alpha 5 integrin, paxillin, and alpha-actinin during formation and disassembly of adhesions in migrating cells. J. Cell Biol. 2001, 153:1427-1440.
    • (2001) J. Cell Biol. , vol.153 , pp. 1427-1440
    • Laukaitis, C.M.1    Webb, D.J.2    Donais, K.3    Horwitz, A.F.4
  • 48
    • 42049092972 scopus 로고    scopus 로고
    • Regulation of actin assembly associated with protrusion and adhesion in cell migration
    • Le Clainche C., Carlier M.F. Regulation of actin assembly associated with protrusion and adhesion in cell migration. Physiol. Rev. 2008, 88:489-513.
    • (2008) Physiol. Rev. , vol.88 , pp. 489-513
    • Le Clainche, C.1    Carlier, M.F.2
  • 49
    • 0347717882 scopus 로고    scopus 로고
    • Cytoplasmic p21Cip1 is involved in Ras-induced inhibition of the ROCK/LIMK/cofilin pathway
    • Lee S., Helfman D.M. Cytoplasmic p21Cip1 is involved in Ras-induced inhibition of the ROCK/LIMK/cofilin pathway. J. Biol. Chem. 2004, 279:1885-1891.
    • (2004) J. Biol. Chem. , vol.279 , pp. 1885-1891
    • Lee, S.1    Helfman, D.M.2
  • 51
    • 0041857759 scopus 로고    scopus 로고
    • P21/CDKN1A mediates negative regulation of transcription by p53
    • Lohr K., Moritz C., Contente A., Dobbelstein M. p21/CDKN1A mediates negative regulation of transcription by p53. J. Biol. Chem. 2003, 278:32507-32516.
    • (2003) J. Biol. Chem. , vol.278 , pp. 32507-32516
    • Lohr, K.1    Moritz, C.2    Contente, A.3    Dobbelstein, M.4
  • 52
    • 0032525331 scopus 로고    scopus 로고
    • Expression of p21WAF1/CIP1 in adenocarcinoma of the uterine cervix: a possible immunohistochemical marker of a favorable prognosis
    • Lu X., Toki T., Konishi I., Nikaido T., Fujii S. Expression of p21WAF1/CIP1 in adenocarcinoma of the uterine cervix: a possible immunohistochemical marker of a favorable prognosis. Cancer 1998, 82:2409-2417.
    • (1998) Cancer , vol.82 , pp. 2409-2417
    • Lu, X.1    Toki, T.2    Konishi, I.3    Nikaido, T.4    Fujii, S.5
  • 53
    • 0029063745 scopus 로고
    • Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1
    • Luo Y., Hurwitz J., Massague J. Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1. Nature 1995, 375:159-161.
    • (1995) Nature , vol.375 , pp. 159-161
    • Luo, Y.1    Hurwitz, J.2    Massague, J.3
  • 56
    • 0022452231 scopus 로고
    • The acetylation of alpha-tubulin and its relationship to the assembly and disassembly of microtubules
    • Maruta H., Greer K., Rosenbaum J.L. The acetylation of alpha-tubulin and its relationship to the assembly and disassembly of microtubules. J. Cell Biol. 1986, 103:571-579.
    • (1986) J. Cell Biol. , vol.103 , pp. 571-579
    • Maruta, H.1    Greer, K.2    Rosenbaum, J.L.3
  • 57
    • 33748286819 scopus 로고    scopus 로고
    • Integrin-regulated FAK-Src signaling in normal and cancer cells
    • Mitra S.K., Schlaepfer D.D. Integrin-regulated FAK-Src signaling in normal and cancer cells. Curr. Opin. Cell Biol. 2006, 18:516-523.
    • (2006) Curr. Opin. Cell Biol. , vol.18 , pp. 516-523
    • Mitra, S.K.1    Schlaepfer, D.D.2
  • 58
    • 69949156933 scopus 로고    scopus 로고
    • The shape of motile cells
    • Mogilner A., Keren K. The shape of motile cells. Curr. Biol. 2009, 19:R762-R771.
    • (2009) Curr. Biol. , vol.19
    • Mogilner, A.1    Keren, K.2
  • 59
    • 24044525270 scopus 로고    scopus 로고
    • C-Myc suppresses p21WAF1/CIP1 expression during estrogen signaling and antiestrogen resistance in human breast cancer cells
    • Mukherjee S., Conrad S.E. c-Myc suppresses p21WAF1/CIP1 expression during estrogen signaling and antiestrogen resistance in human breast cancer cells. J. Biol. Chem. 2005, 280:17617-17625.
    • (2005) J. Biol. Chem. , vol.280 , pp. 17617-17625
    • Mukherjee, S.1    Conrad, S.E.2
  • 60
    • 0037291214 scopus 로고    scopus 로고
    • The human Sir2 ortholog SIRT2, is an NAD+-dependent tubulin deacetylase
    • North B.J., Marshall B.L., Borra M.T., Denu J.M., Verdin E. The human Sir2 ortholog SIRT2, is an NAD+-dependent tubulin deacetylase. Mol. Cell 2003, 11:437-444.
    • (2003) Mol. Cell , vol.11 , pp. 437-444
    • North, B.J.1    Marshall, B.L.2    Borra, M.T.3    Denu, J.M.4    Verdin, E.5
  • 61
    • 0034907213 scopus 로고    scopus 로고
    • MDia mediates Rho-regulated formation and orientation of stable microtubules
    • Palazzo A.F., Cook T.A., Alberts A.S., Gundersen G.G. mDia mediates Rho-regulated formation and orientation of stable microtubules. Nat. Cell Biol. 2001, 3:723-729.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 723-729
    • Palazzo, A.F.1    Cook, T.A.2    Alberts, A.S.3    Gundersen, G.G.4
  • 62
    • 0842331443 scopus 로고    scopus 로고
    • Localized stabilization of microtubules by integrin- and FAK-facilitated Rho signaling
    • Palazzo A.F., Eng C.H., Schlaepfer D.D., Marcantonio E.E., Gundersen G.G. Localized stabilization of microtubules by integrin- and FAK-facilitated Rho signaling. Science 2004, 303:836-839.
    • (2004) Science , vol.303 , pp. 836-839
    • Palazzo, A.F.1    Eng, C.H.2    Schlaepfer, D.D.3    Marcantonio, E.E.4    Gundersen, G.G.5
  • 63
    • 0030057835 scopus 로고    scopus 로고
    • Early alteration of cell-cycle-regulated gene expression in colorectal neoplasia
    • Polyak K., Hamilton S.R., Vogelstein B., Kinzler K.W. Early alteration of cell-cycle-regulated gene expression in colorectal neoplasia. Am. J. Pathol. 1996, 149:381-387.
    • (1996) Am. J. Pathol. , vol.149 , pp. 381-387
    • Polyak, K.1    Hamilton, S.R.2    Vogelstein, B.3    Kinzler, K.W.4
  • 65
    • 0035252089 scopus 로고    scopus 로고
    • Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes
    • Romanov S.R., Kozakiewicz B.K., Holst C.R., Stampfer M.R., Haupt L.M., Tlsty T.D. Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes. Nature 2001, 409:633-637.
    • (2001) Nature , vol.409 , pp. 633-637
    • Romanov, S.R.1    Kozakiewicz, B.K.2    Holst, C.R.3    Stampfer, M.R.4    Haupt, L.M.5    Tlsty, T.D.6
  • 66
    • 0035168410 scopus 로고    scopus 로고
    • Cell cycle-dependent changes in microtubule dynamics in living cells expressing green fluorescent protein-alpha tubulin
    • Rusan N.M., Fagerstrom C.J., Yvon A.M., Wadsworth P. Cell cycle-dependent changes in microtubule dynamics in living cells expressing green fluorescent protein-alpha tubulin. Mol. Biol. Cell 2001, 12:971-980.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 971-980
    • Rusan, N.M.1    Fagerstrom, C.J.2    Yvon, A.M.3    Wadsworth, P.4
  • 67
    • 51649126046 scopus 로고    scopus 로고
    • Destabilization of ERBB2 transcripts by targeting 3' untranslated region messenger RNA associated HuR and histone deacetylase-6
    • Scott G.K., Marx C., Berger C.E., Saunders L.R., Verdin E., Schafer S., Jung M., Benz C.C. Destabilization of ERBB2 transcripts by targeting 3' untranslated region messenger RNA associated HuR and histone deacetylase-6. Mol. Cancer Res. 2008, 6:1250-1258.
    • (2008) Mol. Cancer Res. , vol.6 , pp. 1250-1258
    • Scott, G.K.1    Marx, C.2    Berger, C.E.3    Saunders, L.R.4    Verdin, E.5    Schafer, S.6    Jung, M.7    Benz, C.C.8
  • 68
    • 0029957019 scopus 로고    scopus 로고
    • A non-enzymatic p21 protein inhibitor of stress-activated protein kinases
    • Shim J., Lee H., Park J., Kim H., Choi E.J. A non-enzymatic p21 protein inhibitor of stress-activated protein kinases. Nature 1996, 381:804-806.
    • (1996) Nature , vol.381 , pp. 804-806
    • Shim, J.1    Lee, H.2    Park, J.3    Kim, H.4    Choi, E.J.5
  • 69
    • 0037221714 scopus 로고    scopus 로고
    • Microtubules meet substrate adhesions to arrange cell polarity
    • Small J.V., Kaverina I. Microtubules meet substrate adhesions to arrange cell polarity. Curr. Opin. Cell Biol. 2003, 15:40-47.
    • (2003) Curr. Opin. Cell Biol. , vol.15 , pp. 40-47
    • Small, J.V.1    Kaverina, I.2
  • 70
    • 0033894919 scopus 로고    scopus 로고
    • Procaspase 3/p21 complex formation to resist fas-mediated cell death is initiated as a result of the phosphorylation of p21 by protein kinase A
    • Suzuki A., Kawano H., Hayashida M., Hayasaki Y., Tsutomi Y., Akahane K. Procaspase 3/p21 complex formation to resist fas-mediated cell death is initiated as a result of the phosphorylation of p21 by protein kinase A. Cell Death. Differ. 2000, 7:721-728.
    • (2000) Cell Death. Differ. , vol.7 , pp. 721-728
    • Suzuki, A.1    Kawano, H.2    Hayashida, M.3    Hayasaki, Y.4    Tsutomi, Y.5    Akahane, K.6
  • 71
    • 0033521925 scopus 로고    scopus 로고
    • Caspase 3 inactivation to suppress Fas-mediated apoptosis: identification of binding domain with p21 and ILP and inactivation machinery by p21
    • Suzuki A., Tsutomi Y., Miura M., Akahane K. Caspase 3 inactivation to suppress Fas-mediated apoptosis: identification of binding domain with p21 and ILP and inactivation machinery by p21. Oncogene 1999, 18:1239-1244.
    • (1999) Oncogene , vol.18 , pp. 1239-1244
    • Suzuki, A.1    Tsutomi, Y.2    Miura, M.3    Akahane, K.4
  • 72
    • 0037157872 scopus 로고    scopus 로고
    • Cytoplasmic p21(Cip1/WAF1) regulates neurite remodeling by inhibiting Rho-kinase activity
    • Tanaka H., Yamashita T., Asada M., Mizutani S., Yoshikawa H., Tohyama M. Cytoplasmic p21(Cip1/WAF1) regulates neurite remodeling by inhibiting Rho-kinase activity. J. Cell Biol. 2002, 158:321-329.
    • (2002) J. Cell Biol. , vol.158 , pp. 321-329
    • Tanaka, H.1    Yamashita, T.2    Asada, M.3    Mizutani, S.4    Yoshikawa, H.5    Tohyama, M.6
  • 73
    • 70349332774 scopus 로고    scopus 로고
    • Focal adhesion kinase: switching between GAPs and GEFs in the regulation of cell motility
    • Tomar A., Schlaepfer D.D. Focal adhesion kinase: switching between GAPs and GEFs in the regulation of cell motility. Curr. Opin. Cell Biol. 2009, 21:676-683.
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 676-683
    • Tomar, A.1    Schlaepfer, D.D.2
  • 79
    • 0034660513 scopus 로고    scopus 로고
    • Risky immortalization by telomerase
    • Wang J., Hannon G.J., Beach D.H. Risky immortalization by telomerase. Nature 2000, 405:755-756.
    • (2000) Nature , vol.405 , pp. 755-756
    • Wang, J.1    Hannon, G.J.2    Beach, D.H.3
  • 80
    • 0030727892 scopus 로고    scopus 로고
    • Actomyosin-based retrograde flow of microtubules in the lamella of migrating epithelial cells influences microtubule dynamic instability and turnover and is associated with microtubule breakage and treadmilling
    • Waterman-Storer C.M., Salmon E.D. Actomyosin-based retrograde flow of microtubules in the lamella of migrating epithelial cells influences microtubule dynamic instability and turnover and is associated with microtubule breakage and treadmilling. J. Cell Biol. 1997, 139:417-434.
    • (1997) J. Cell Biol. , vol.139 , pp. 417-434
    • Waterman-Storer, C.M.1    Salmon, E.D.2
  • 83
    • 0345169048 scopus 로고    scopus 로고
    • Post-translational modifications regulate microtubule function
    • Westermann S., Weber K. Post-translational modifications regulate microtubule function. Nat. Rev. Mol. Cell Biol. 2003, 4:938-947.
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 938-947
    • Westermann, S.1    Weber, K.2
  • 84
    • 0038457895 scopus 로고    scopus 로고
    • Regulation of leading edge microtubule and actin dynamics downstream of Rac1
    • Wittmann T., Bokoch G.M., Waterman-Storer C.M. Regulation of leading edge microtubule and actin dynamics downstream of Rac1. J. Cell Biol. 2003, 161:845-851.
    • (2003) J. Cell Biol. , vol.161 , pp. 845-851
    • Wittmann, T.1    Bokoch, G.M.2    Waterman-Storer, C.M.3
  • 85
    • 1242271991 scopus 로고    scopus 로고
    • Regulation of microtubule destabilizing activity of Op18/stathmin downstream of Rac1
    • Wittmann T., Bokoch G.M., Waterman-Storer C.M. Regulation of microtubule destabilizing activity of Op18/stathmin downstream of Rac1. J. Biol. Chem. 2004, 279:6196-6203.
    • (2004) J. Biol. Chem. , vol.279 , pp. 6196-6203
    • Wittmann, T.1    Bokoch, G.M.2    Waterman-Storer, C.M.3
  • 88
    • 65349132693 scopus 로고    scopus 로고
    • EMT, the cytoskeleton, and cancer cell invasion
    • Yilmaz M., Christofori G. EMT, the cytoskeleton, and cancer cell invasion. Cancer Metastasis Rev. 2009, 28:15-33.
    • (2009) Cancer Metastasis Rev. , vol.28 , pp. 15-33
    • Yilmaz, M.1    Christofori, G.2
  • 90
    • 56149118852 scopus 로고    scopus 로고
    • Memo-RhoA-mDia1 signaling controls microtubules, the actin network, and adhesion site formation in migrating cells
    • Zaoui K., Honore S., Isnardon D., Braguer D., Badache A. Memo-RhoA-mDia1 signaling controls microtubules, the actin network, and adhesion site formation in migrating cells. J. Cell Biol. 2008, 183:401-408.
    • (2008) J. Cell Biol. , vol.183 , pp. 401-408
    • Zaoui, K.1    Honore, S.2    Isnardon, D.3    Braguer, D.4    Badache, A.5
  • 91
    • 34247577963 scopus 로고    scopus 로고
    • Negative regulation of ASK1 by p21Cip1 involves a small domain that includes Serine 98 that is phosphorylated by ASK1 in vivo
    • Zhan J., Easton J.B., Huang S., Mishra A., Xiao L., Lacy E.R., Kriwacki R.W., Houghton P.J. Negative regulation of ASK1 by p21Cip1 involves a small domain that includes Serine 98 that is phosphorylated by ASK1 in vivo. Mol. Cell Biol. 2007, 27:3530-3541.
    • (2007) Mol. Cell Biol. , vol.27 , pp. 3530-3541
    • Zhan, J.1    Easton, J.B.2    Huang, S.3    Mishra, A.4    Xiao, L.5    Lacy, E.R.6    Kriwacki, R.W.7    Houghton, P.J.8
  • 93
    • 0034745353 scopus 로고    scopus 로고
    • Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells
    • Zhou B.P., Liao Y., Xia W., Spohn B., Lee M.H., Hung M.C. Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells. Nat. Cell Biol. 2001, 3:245-252.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 245-252
    • Zhou, B.P.1    Liao, Y.2    Xia, W.3    Spohn, B.4    Lee, M.H.5    Hung, M.C.6
  • 95
    • 0035176077 scopus 로고    scopus 로고
    • Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation
    • Zumbrunn J., Kinoshita K., Hyman A.A., Nathke I.S. Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation. Curr. Biol. 2001, 11:44-49.
    • (2001) Curr. Biol. , vol.11 , pp. 44-49
    • Zumbrunn, J.1    Kinoshita, K.2    Hyman, A.A.3    Nathke, I.S.4


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