-
2
-
-
0036273491
-
Evolutionary conservation of microtubule-capture mechanisms
-
•]) present mechanisms of microtubule interaction with actin and their mutual regulation. The authors uncover interesting analogies in different cell types.
-
•]) present mechanisms of microtubule interaction with actin and their mutual regulation. The authors uncover interesting analogies in different cell types.
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 296-304
-
-
Gundersen, G.G.1
-
3
-
-
0035975991
-
Roles of the fission yeast formin for3p in cell polarity, actin cable formation and symmetric cell division
-
Feierbach B., Chang F. Roles of the fission yeast formin for3p in cell polarity, actin cable formation and symmetric cell division. Curr. Biol. 11:2001;1656-1665.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1656-1665
-
-
Feierbach, B.1
Chang, F.2
-
4
-
-
0036049615
-
An actin nucleation mechanism mediated by Bni1 and profilin
-
Sagot I., Rodal A.A., Moseley J., Goode B.L., Pellman D. An actin nucleation mechanism mediated by Bni1 and profilin. Nat. Cell Biol. 4:2002;626-631.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 626-631
-
-
Sagot, I.1
Rodal, A.A.2
Moseley, J.3
Goode, B.L.4
Pellman, D.5
-
5
-
-
0036514271
-
Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast
-
Evangelista M., Pruyne D., Amberg D.C., Boone C., Bretscher A. Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast. Nat. Cell Biol. 4:2002;260-269.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 260-269
-
-
Evangelista, M.1
Pruyne, D.2
Amberg, D.C.3
Boone, C.4
Bretscher, A.5
-
6
-
-
0037178706
-
Role of formins in actin assembly: Nucleation and barbed-end association
-
Pruyne D., Evangelista M., Yang C., Bi E., Zigmond S., Bretscher A., Boone C. Role of formins in actin assembly: nucleation and barbed-end association. Science. 297:2002;612-615.
-
(2002)
Science
, vol.297
, pp. 612-615
-
-
Pruyne, D.1
Evangelista, M.2
Yang, C.3
Bi, E.4
Zigmond, S.5
Bretscher, A.6
Boone, C.7
-
7
-
-
0028961293
-
Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
-
Nobes C.D., Hall A. Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell. 81:1995;53-62.
-
(1995)
Cell
, vol.81
, pp. 53-62
-
-
Nobes, C.D.1
Hall, A.2
-
8
-
-
0030940218
-
Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages
-
Allen W.E., Jones G.E., Pollard J.W., Ridley A.J. Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages. J. Cell Sci. 110:1997;707-720.
-
(1997)
J. Cell Sci.
, vol.110
, pp. 707-720
-
-
Allen, W.E.1
Jones, G.E.2
Pollard, J.W.3
Ridley, A.J.4
-
9
-
-
0033577975
-
Interplay between Rac and Rho in the control of substrate contact dynamics
-
Rottner K., Hall A., Small J.V. Interplay between Rac and Rho in the control of substrate contact dynamics. Curr. Biol. 9:1999;640-648.
-
(1999)
Curr. Biol.
, vol.9
, pp. 640-648
-
-
Rottner, K.1
Hall, A.2
Small, J.V.3
-
11
-
-
0036222784
-
Adhesion assembly, disassembly and turnover in migrating cells - Over and over and over again
-
This is a very informative, up-to date review on adhesion dynamics and its regulation in motile cells.
-
Webb D.J., Parsons J.T., Horwitz A.F. Adhesion assembly, disassembly and turnover in migrating cells - over and over and over again. Nat. Cell Biol. 4:2002;E97-E100 This is a very informative, up-to date review on adhesion dynamics and its regulation in motile cells.
-
(2002)
Nat. Cell Biol.
, vol.4
-
-
Webb, D.J.1
Parsons, J.T.2
Horwitz, A.F.3
-
12
-
-
0033160196
-
Cooperation between mDia1 and ROCK in Rho-induced actin reorganization
-
Watanabe N., Kato T., Fujita A., Ishizaki T., Narumiya S. Cooperation between mDia1 and ROCK in Rho-induced actin reorganization. Nat. Cell Biol. 1:1999;136-143.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 136-143
-
-
Watanabe, N.1
Kato, T.2
Fujita, A.3
Ishizaki, T.4
Narumiya, S.5
-
13
-
-
0035479910
-
Assembly and mechanosensory function of focal contacts
-
Geiger B., Bershadsky A. Assembly and mechanosensory function of focal contacts. Curr. Opin. Cell Biol. 13:2001;584-592.
-
(2001)
Curr. Opin. Cell Biol.
, vol.13
, pp. 584-592
-
-
Geiger, B.1
Bershadsky, A.2
-
14
-
-
0035158377
-
RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity
-
This is a fascinating study that elaborates on the adhesion-induced mechanism of Rho suppression that is transmitted via integrin-triggered Rho GAP activation. It is shown that Rho downregulation is necessary for both spreading and the establishment of cell polarity, and therefore for motility.
-
Arthur W.T., Burridge K. RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity. Mol. Biol. Cell. 12:2001;2711-2720 This is a fascinating study that elaborates on the adhesion-induced mechanism of Rho suppression that is transmitted via integrin-triggered Rho GAP activation. It is shown that Rho downregulation is necessary for both spreading and the establishment of cell polarity, and therefore for motility.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 2711-2720
-
-
Arthur, W.T.1
Burridge, K.2
-
15
-
-
18444414614
-
ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts
-
This, a very interesting paper, provides new insights on the interplay between Rho family GTPases. mDia is shown to induce Rac activation, in a new pathway downstream from Rho.
-
Tsuji T., Ishizaki T., Okamoto M., Higashida C., Kimura K., Furuyashiki T., Arakawa Y., Birge R.B., Nakamoto T., Hirai H.et al. ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts. J. Cell Biol. 157:2002;819-830 This, a very interesting paper, provides new insights on the interplay between Rho family GTPases. mDia is shown to induce Rac activation, in a new pathway downstream from Rho.
-
(2002)
J. Cell Biol.
, vol.157
, pp. 819-830
-
-
Tsuji, T.1
Ishizaki, T.2
Okamoto, M.3
Higashida, C.4
Kimura, K.5
Furuyashiki, T.6
Arakawa, Y.7
Birge, R.B.8
Nakamoto, T.9
Hirai, H.10
-
16
-
-
0033594123
-
Rho GTPases control polarity, protrusion, and adhesion during cell movement
-
Nobes C.D., Hall A. Rho GTPases control polarity, protrusion, and adhesion during cell movement. J. Cell Biol. 144:1999;1235-1244.
-
(1999)
J. Cell Biol.
, vol.144
, pp. 1235-1244
-
-
Nobes, C.D.1
Hall, A.2
-
17
-
-
0034865456
-
Rho GTPases and cell migration
-
Ridley A.J. Rho GTPases and cell migration. J. Cell Sci. 114:2001;2713-2722.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 2713-2722
-
-
Ridley, A.J.1
-
18
-
-
0035858878
-
Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts
-
Beningo K.A., Dembo M., Kaverina I., Small J.V., Wang Y.L. Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts. J. Cell Biol. 153:2001;881-888.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 881-888
-
-
Beningo, K.A.1
Dembo, M.2
Kaverina, I.3
Small, J.V.4
Wang, Y.L.5
-
20
-
-
0035945353
-
Marching at the front and dragging behind: Differential alphaVbeta3-integrin turnover regulates focal adhesion behavior
-
The authors describe high-quality imaging of the distribution and properties of β3 integrins throughout the development of substrate adhesions from focal complexes to trailing focal adhesions. Adhesions are classified according to integrin density, and the apparent sliding of trailing adhesions is shown to correlate with a linear turnover of adhesion components. The role of tensile stress on integrin density is also emphasised.
-
Ballestrem C., Hinz B., Imhof B.A., Wehrle-Haller B. Marching at the front and dragging behind: differential alphaVbeta3-integrin turnover regulates focal adhesion behavior. J. Cell Biol. 155:2001;1319-1332 The authors describe high-quality imaging of the distribution and properties of β3 integrins throughout the development of substrate adhesions from focal complexes to trailing focal adhesions. Adhesions are classified according to integrin density, and the apparent sliding of trailing adhesions is shown to correlate with a linear turnover of adhesion components. The role of tensile stress on integrin density is also emphasised.
-
(2001)
J. Cell Biol.
, vol.155
, pp. 1319-1332
-
-
Ballestrem, C.1
Hinz, B.2
Imhof, B.A.3
Wehrle-Haller, B.4
-
22
-
-
0035833247
-
RhoA is required for monocyte tail retraction during transendothelial migration
-
Worthylake R.A., Lemoine S., Watson J.M., Burridge K. RhoA is required for monocyte tail retraction during transendothelial migration. J. Cell Biol. 54:2001;147-160.
-
(2001)
J. Cell Biol.
, vol.54
, pp. 147-160
-
-
Worthylake, R.A.1
Lemoine, S.2
Watson, J.M.3
Burridge, K.4
-
23
-
-
0036070518
-
Spatiotemporal regulation of moesin phosphorylation and rear release by Rho and serine/threonine phosphatase during neutrophil migration
-
Yoshinaga-Ohara N., Takahashi A., Uchiyama T., Sasada M. Spatiotemporal regulation of moesin phosphorylation and rear release by Rho and serine/threonine phosphatase during neutrophil migration. Exp. Cell Res. 278:2002;112-122.
-
(2002)
Exp. Cell Res.
, vol.278
, pp. 112-122
-
-
Yoshinaga-Ohara, N.1
Takahashi, A.2
Uchiyama, T.3
Sasada, M.4
-
24
-
-
0027366484
-
Microtubules, centrosomes and intermediate filaments in directed cell movement
-
Schliwa MaH B. Microtubules, centrosomes and intermediate filaments in directed cell movement. Trends Cell Biol. 3:1993;377-380.
-
(1993)
Trends Cell Biol.
, vol.3
, pp. 377-380
-
-
Schliwa MaH, B.1
-
26
-
-
0035178210
-
Cell motility: Can Rho GTPases and microtubules point the way?
-
This is a thorough review that focuses on the role of Rho GTPase signalling in the interplay and feedback between microtubules and actin in cell polarisation and motility. It includes interesting and alternative speculations about the influence of microtubules on actin cytoskeleton dynamics.
-
Wittmann T., Waterman-Storer C.M. Cell motility: can Rho GTPases and microtubules point the way? J. Cell Sci. 114:2001;3795-3803 This is a thorough review that focuses on the role of Rho GTPase signalling in the interplay and feedback between microtubules and actin in cell polarisation and motility. It includes interesting and alternative speculations about the influence of microtubules on actin cytoskeleton dynamics.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 3795-3803
-
-
Wittmann, T.1
Waterman-Storer, C.M.2
-
27
-
-
0033130049
-
Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts
-
Waterman-Storer C.M., Worthylake R.A., Liu B.P., Burridge K., Salmon E.D. Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts. Nat. Cell Biol. 1:1999;45-50.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 45-50
-
-
Waterman-Storer, C.M.1
Worthylake, R.A.2
Liu, B.P.3
Burridge, K.4
Salmon, E.D.5
-
28
-
-
0035910554
-
Rac/Cdc42 and p65PAK regulate the microtubule-destabilizing protein stathmin through phosphorylation at serine 16
-
This study shows that microtubule-destabilising activity of stathmin can be inhibited by specific PAK-dependent phosphorylation downstream of Rac/Cdc42. These data provide evidence for Rac/Cdc42-regulated microtubule dynamics.
-
Daub H., Gevaert K., Vandekerckhove J., Sobel A., Hall A. Rac/Cdc42 and p65PAK regulate the microtubule-destabilizing protein stathmin through phosphorylation at serine 16. J. Biol. Chem. 276:2001;1677-1680 This study shows that microtubule-destabilising activity of stathmin can be inhibited by specific PAK-dependent phosphorylation downstream of Rac/Cdc42. These data provide evidence for Rac/Cdc42-regulated microtubule dynamics.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 1677-1680
-
-
Daub, H.1
Gevaert, K.2
Vandekerckhove, J.3
Sobel, A.4
Hall, A.5
-
29
-
-
0034492210
-
Actin-dependent lamellipodia formation and microtubule-dependent tail retraction control-directed cell migration
-
Ballestrem C., Wehrle-Haller B., Hinz B., Imhof B.A. Actin-dependent lamellipodia formation and microtubule-dependent tail retraction control-directed cell migration. Mol. Biol. Cell. 11:2000;2999-3012.
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 2999-3012
-
-
Ballestrem, C.1
Wehrle-Haller, B.2
Hinz, B.3
Imhof, B.A.4
-
30
-
-
0032872870
-
Microtubule targeting of substrate contacts promotes their relaxation and dissociation
-
Kaverina I., Krylyshkina O., Small J.V. Microtubule targeting of substrate contacts promotes their relaxation and dissociation. J. Cell Biol. 146:1999;1033-1044.
-
(1999)
J. Cell Biol.
, vol.146
, pp. 1033-1044
-
-
Kaverina, I.1
Krylyshkina, O.2
Small, J.V.3
-
31
-
-
0034659215
-
Enforced polarisation and locomotion of fibroblasts lacking microtubules
-
Kaverina I., Krylyshkina O., Gimona M., Beningo K., Wang Y.L., Small J.V. Enforced polarisation and locomotion of fibroblasts lacking microtubules. Curr. Biol. 10:2000;739-742.
-
(2000)
Curr. Biol.
, vol.10
, pp. 739-742
-
-
Kaverina, I.1
Krylyshkina, O.2
Gimona, M.3
Beningo, K.4
Wang, Y.L.5
Small, J.V.6
-
32
-
-
0035838422
-
Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization
-
Nakamura M., Zhou X.Z., Lu K.P. Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization. Curr. Biol. 11:2001;1062-1067.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1062-1067
-
-
Nakamura, M.1
Zhou, X.Z.2
Lu, K.P.3
-
33
-
-
0034614936
-
Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cells
-
Mimori-Kiyosue Y., Shiina N., Tsukita S. Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cells. J. Cell Biol. 148:2000;505-518.
-
(2000)
J. Cell Biol.
, vol.148
, pp. 505-518
-
-
Mimori-Kiyosue, Y.1
Shiina, N.2
Tsukita, S.3
-
34
-
-
0034682888
-
Asef, a link between the tumor suppressor APC and G-protein signaling
-
Kawasaki Y., Senda T., Ishidate T., Koyama R., Morishita T., Iwayama Y., Higuchi O., Akiyama T. Asef, a link between the tumor suppressor APC and G-protein signaling. Science. 289:2000;1194-1197.
-
(2000)
Science
, vol.289
, pp. 1194-1197
-
-
Kawasaki, Y.1
Senda, T.2
Ishidate, T.3
Koyama, R.4
Morishita, T.5
Iwayama, Y.6
Higuchi, O.7
Akiyama, T.8
-
35
-
-
0033615966
-
Rac downregulates Rho activity: Reciprocal balance between both GTPases determines cellular morphology and migratory behavior
-
Sander E.E., ten Klooster J.P., van Delft S., van der Kammen R.A., Collard J.G. Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior. J. Cell Biol. 147:1999;1009-1022.
-
(1999)
J. Cell Biol.
, vol.147
, pp. 1009-1022
-
-
Sander, E.E.1
Ten Klooster, J.P.2
Van Delft, S.3
Van der Kammen, R.A.4
Collard, J.G.5
-
36
-
-
18444369936
-
Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170
-
This paper provides strong evidence for the Rac/Cdc42-dependent binding of the effector protein IQGAP1 with microtubule tips via CLIP-170. The disturbance of this association leads to the lost of cell polarity.
-
Fukata M., Watanabe T., Noritake J., Nakagawa M., Yamaga M., Kuroda S., Matsuura Y., Iwamatsu A., Perez F., Kaibuchi K. Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170. Cell. 109:2002;873-885 This paper provides strong evidence for the Rac/Cdc42-dependent binding of the effector protein IQGAP1 with microtubule tips via CLIP-170. The disturbance of this association leads to the lost of cell polarity.
-
(2002)
Cell
, vol.109
, pp. 873-885
-
-
Fukata, M.1
Watanabe, T.2
Noritake, J.3
Nakagawa, M.4
Yamaga, M.5
Kuroda, S.6
Matsuura, Y.7
Iwamatsu, A.8
Perez, F.9
Kaibuchi, K.10
-
37
-
-
0034266786
-
CLIP170-like tip1p spatially organizes microtubular dynamics in fission yeast
-
Brunner D., Nurse P. CLIP170-like tip1p spatially organizes microtubular dynamics in fission yeast. Cell. 102:2000;695-704.
-
(2000)
Cell
, vol.102
, pp. 695-704
-
-
Brunner, D.1
Nurse, P.2
-
38
-
-
17744372880
-
CLASPs are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts
-
A new family of microtubule-tip proteins (CLASPs) is essential for the asymmetric orientation of stable microtubule arrays in a wound healing assay. CLASPs localise to a subset of plus-ends, preferentially in the front part of the cell and therefore may be involved in certain aspects of microtubule-dependent cell polarisation.
-
Akhmanova A., Hoogenraad C.C., Drabek K., Stepanova T., Dortland B., Verkerk T., Vermeulen W., Burgering B.M., De Zeeuw C.I., Grosveld F.et al. CLASPs are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts. Cell. 104:2001;923-935 A new family of microtubule-tip proteins (CLASPs) is essential for the asymmetric orientation of stable microtubule arrays in a wound healing assay. CLASPs localise to a subset of plus-ends, preferentially in the front part of the cell and therefore may be involved in certain aspects of microtubule-dependent cell polarisation.
-
(2001)
Cell
, vol.104
, pp. 923-935
-
-
Akhmanova, A.1
Hoogenraad, C.C.2
Drabek, K.3
Stepanova, T.4
Dortland, B.5
Verkerk, T.6
Vermeulen, W.7
Burgering, B.M.8
De Zeeuw, C.I.9
Grosveld, F.10
-
39
-
-
0032567341
-
Cloning and characterization of GEF-H1, a microtubule-associated guanine nucleotide exchange factor for Rac and Rho GTPases
-
Ren Y., Li R., Zheng Y., Busch H. Cloning and characterization of GEF-H1, a microtubule-associated guanine nucleotide exchange factor for Rac and Rho GTPases. J. Biol. Chem. 273:1998;34954-34960.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34954-34960
-
-
Ren, Y.1
Li, R.2
Zheng, Y.3
Busch, H.4
-
40
-
-
0033593337
-
The Dbl-related protein, Lfc, localizes to microtubules and mediates the activation of Rac signaling pathways in cells
-
Glaven J.A., Whitehead I., Bagrodia S., Kay R., Cerione R.A. The Dbl-related protein, Lfc, localizes to microtubules and mediates the activation of Rac signaling pathways in cells. J. Biol. Chem. 274:1999;2279-2285.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 2279-2285
-
-
Glaven, J.A.1
Whitehead, I.2
Bagrodia, S.3
Kay, R.4
Cerione, R.A.5
-
41
-
-
0035895915
-
Characterization of p190RhoGEF, a RhoA-specific guanine nucleotide exchange factor that interacts with microtubules
-
van Horck F.P., Ahmadian M.R., Haeusler L.C., Moolenaar W.H., Kranenburg O. Characterization of p190RhoGEF, a RhoA-specific guanine nucleotide exchange factor that interacts with microtubules. J. Biol. Chem. 276:2001;4948-4956.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 4948-4956
-
-
Van Horck, F.P.1
Ahmadian, M.R.2
Haeusler, L.C.3
Moolenaar, W.H.4
Kranenburg, O.5
-
42
-
-
0036228955
-
Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton
-
The authors describe the first direct evidence that microtubule binding of a regulatory molecule can modulate the activity of a Rho-family GTPase. The Rho-specific exchange factor GEF H1 is active only when it is not bound to microtubules.
-
Krendel M., Zenke F.T., Bokoch G.M. Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton. Nat. Cell Biol. 4:2002;294-301 The authors describe the first direct evidence that microtubule binding of a regulatory molecule can modulate the activity of a Rho-family GTPase. The Rho-specific exchange factor GEF H1 is active only when it is not bound to microtubules.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 294-301
-
-
Krendel, M.1
Zenke, F.T.2
Bokoch, G.M.3
-
43
-
-
0030462929
-
Microtubule disruption induces the formation of actin stress fibers and focal adhesions in cultured cells: Possible involvement of the Rho signal cascade
-
Enomoto T. Microtubule disruption induces the formation of actin stress fibers and focal adhesions in cultured cells: possible involvement of the Rho signal cascade. Cell Struct. Funct. 21:1996;317-326.
-
(1996)
Cell Struct. Funct.
, vol.21
, pp. 317-326
-
-
Enomoto, T.1
-
44
-
-
0032514208
-
Targeting, capture, and stabilization of microtubules at early focal adhesions
-
Kaverina I., Rottner K., Small J.V. Targeting, capture, and stabilization of microtubules at early focal adhesions. J. Cell Biol. 142:1998;181-190.
-
(1998)
J. Cell Biol.
, vol.142
, pp. 181-190
-
-
Kaverina, I.1
Rottner, K.2
Small, J.V.3
-
45
-
-
0037148524
-
Modulation of substrate adhesion dynamics via microtubule targeting requires kinesin-1
-
This study shows that the influence of microtubules on adhesion dynamics is dependent on kinesin-1. A block of kinesin, but not of dynein, caused similar changes in adhesion patterns to those observed following microtubule disruption with nocodazole.
-
Krylyshkina O., Kaverina I., Kranewitter W., Steffen W., Alonso M.C., Cross R.A., Small J.V. Modulation of substrate adhesion dynamics via microtubule targeting requires kinesin-1. J. Cell Biol. 156:2002;349-360 This study shows that the influence of microtubules on adhesion dynamics is dependent on kinesin-1. A block of kinesin, but not of dynein, caused similar changes in adhesion patterns to those observed following microtubule disruption with nocodazole.
-
(2002)
J. Cell Biol.
, vol.156
, pp. 349-360
-
-
Krylyshkina, O.1
Kaverina, I.2
Kranewitter, W.3
Steffen, W.4
Alonso, M.C.5
Cross, R.A.6
Small, J.V.7
-
46
-
-
0035168371
-
Kinectin is a key effector of RhoG microtubule-dependent cellular activity
-
Vignal E., Blangy A., Martin M., Gauthier-Rouviere C., Fort P. Kinectin is a key effector of RhoG microtubule-dependent cellular activity. Mol. Cell Biol. 21:2001;8022-8034.
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 8022-8034
-
-
Vignal, E.1
Blangy, A.2
Martin, M.3
Gauthier-Rouviere, C.4
Fort, P.5
-
47
-
-
0031610579
-
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
-
Manser E., Loo T.H., Koh C.G., Zhao Z.S., Chen X.Q., Tan L., Tan I., Leung T., Lim L. PAK kinases are directly coupled to the PIX family of nucleotide exchange factors. Mol. Cell. 1:1998;183-192.
-
(1998)
Mol. Cell
, vol.1
, pp. 183-192
-
-
Manser, E.1
Loo, T.H.2
Koh, C.G.3
Zhao, Z.S.4
Chen, X.Q.5
Tan, L.6
Tan, I.7
Leung, T.8
Lim, L.9
-
48
-
-
0034739851
-
Temporal and spatial distribution of activated Pak1 in fibroblasts
-
Sells M.A., Pfaff A., Chernoff J. Temporal and spatial distribution of activated Pak1 in fibroblasts. J. Cell Biol. 151:2000;1449-1458.
-
(2000)
J. Cell Biol.
, vol.151
, pp. 1449-1458
-
-
Sells, M.A.1
Pfaff, A.2
Chernoff, J.3
-
49
-
-
0035999990
-
Paxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involves a multistep activation pathway
-
Brown M.C., West K.A., Turner C.E. Paxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involves a multistep activation pathway. Mol. Biol. Cell. 13:2002;1550-1565.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 1550-1565
-
-
Brown, M.C.1
West, K.A.2
Turner, C.E.3
-
50
-
-
0035844869
-
Focal contacts as mechanosensors: Externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism
-
Riveline D., Zamir E., Balaban N.Q., Schwarz U.S., Ishizaki T., Narumiya S., Kam Z., Geiger B., Bershadsky A.D. Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism. J. Cell Biol. 153:2001;1175-1186.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 1175-1186
-
-
Riveline, D.1
Zamir, E.2
Balaban, N.Q.3
Schwarz, U.S.4
Ishizaki, T.5
Narumiya, S.6
Kam, Z.7
Geiger, B.8
Bershadsky, A.D.9
-
51
-
-
0036591961
-
Tensile stress stimulates microtubule outgrowth in living cells
-
This work shows that tensile stress applied to cells promotes microtubule polymerisation into the stressed regions and into adhesion foci amplified by stress. Microtubule polymerisation dynamics is therefore influenced by a mechanical force factor and thus joins the group of processes in which stress-induced conformational changes are associated with signal transmission.
-
Kaverina I., Krylyshkina O., Beningo K., Anderson K., Wang Y.-L., Small J.V. Tensile stress stimulates microtubule outgrowth in living cells. J. Cell Sci. 115:2002;2283-2291 This work shows that tensile stress applied to cells promotes microtubule polymerisation into the stressed regions and into adhesion foci amplified by stress. Microtubule polymerisation dynamics is therefore influenced by a mechanical force factor and thus joins the group of processes in which stress-induced conformational changes are associated with signal transmission.
-
(2002)
J. Cell Sci.
, vol.115
, pp. 2283-2291
-
-
Kaverina, I.1
Krylyshkina, O.2
Beningo, K.3
Anderson, K.4
Wang, Y.-L.5
Small, J.V.6
-
52
-
-
0034907213
-
MDia mediates Rho-regulated formation and orientation of stable microtubules
-
Palazzo A.F., Cook T.A., Alberts A.S., Gundersen G.G. mDia mediates Rho-regulated formation and orientation of stable microtubules. Nat. Cell Biol. 3:2001;723-729.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 723-729
-
-
Palazzo, A.F.1
Cook, T.A.2
Alberts, A.S.3
Gundersen, G.G.4
-
53
-
-
0035141074
-
Coordination of microtubules and the actin cytoskeleton by the Rho effector mDia1
-
Ishizaki T., Morishima Y., Okamoto M., Furuyashiki T., Kato T., Narumiya S. Coordination of microtubules and the actin cytoskeleton by the Rho effector mDia1. Nat. Cell Biol. 3:2001;8-14.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 8-14
-
-
Ishizaki, T.1
Morishima, Y.2
Okamoto, M.3
Furuyashiki, T.4
Kato, T.5
Narumiya, S.6
-
54
-
-
0037043342
-
Dual-wavelength fluorescent speckle microscopy reveals coupling of microtubule and actin movements in migrating cells
-
Salmon W.C., Adams M.C., Waterman-Storer C.M. Dual-wavelength fluorescent speckle microscopy reveals coupling of microtubule and actin movements in migrating cells. J. Cell Biol. 158:2002;31-37.
-
(2002)
J. Cell Biol.
, vol.158
, pp. 31-37
-
-
Salmon, W.C.1
Adams, M.C.2
Waterman-Storer, C.M.3
-
55
-
-
0037043343
-
Filopodia and actin arcs guide the assembly and transport of two populations of microtubules with unique dynamic parameters in neuronal growth cones
-
Schaefer A.W., Kabir N., Forscher P. Filopodia and actin arcs guide the assembly and transport of two populations of microtubules with unique dynamic parameters in neuronal growth cones. J. Cell Biol. 158:2002;139-152.
-
(2002)
J. Cell Biol.
, vol.158
, pp. 139-152
-
-
Schaefer, A.W.1
Kabir, N.2
Forscher, P.3
-
57
-
-
0036227387
-
Roles for the tubulin- and PTP-PEST-binding paxillin LIM domains in cell adhesion and motility
-
Brown M.C., Turner C.E. Roles for the tubulin- and PTP-PEST-binding paxillin LIM domains in cell adhesion and motility. Int. J. Biochem. Cell Biol. 34:2002;855-863.
-
(2002)
Int. J. Biochem. Cell Biol.
, vol.34
, pp. 855-863
-
-
Brown, M.C.1
Turner, C.E.2
-
60
-
-
0034644119
-
The dynamic behavior of the APC-binding protein EB1 on the distal ends of microtubules
-
Mimori-Kiyosue Y., Shiina N., Tsukita S. The dynamic behavior of the APC-binding protein EB1 on the distal ends of microtubules. Curr. Biol. 10:2000;865-868.
-
(2000)
Curr. Biol.
, vol.10
, pp. 865-868
-
-
Mimori-Kiyosue, Y.1
Shiina, N.2
Tsukita, S.3
-
61
-
-
0036915826
-
Microtubule asymmetry during neutrophil polarization and migration
-
in press
-
Eddy JE, Pierini LM, Maxfield FR: Microtubule asymmetry during neutrophil polarization and migration. Mol Biol Cell 2002, in press.
-
(2002)
Mol Biol Cell
-
-
Eddy, J.E.1
Pierini, L.M.2
Maxfield, F.R.3
-
62
-
-
0034739004
-
Myosin V orients the mitotic spindle in yeast
-
Yin H., Pruyne D., Huffaker T.C., Bretscher A. Myosin V orients the mitotic spindle in yeast. Nature. 406:2000;1013-1015.
-
(2000)
Nature
, vol.406
, pp. 1013-1015
-
-
Yin, H.1
Pruyne, D.2
Huffaker, T.C.3
Bretscher, A.4
-
63
-
-
0036645506
-
Microtubule capture by the cleavage apparatus is required for proper spindle positioning in yeast
-
Kusch J., Meyer A., Snyder M.P., Barral Y. Microtubule capture by the cleavage apparatus is required for proper spindle positioning in yeast. Genes Dev. 16:2002;1627-1639.
-
(2002)
Genes Dev.
, vol.16
, pp. 1627-1639
-
-
Kusch, J.1
Meyer, A.2
Snyder, M.P.3
Barral, Y.4
|