Timing requirements for insulin/IGF-1 signaling in C. elegans

Science

Volumn 298, Issue 5594, 2002, Pages 830-834

  Dillin, Andrew ^a   Crawford, Douglas K ^a   Kenyon, Cynthia ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODIVERSITY; PHYSIOLOGY;

REPRODUCTION;

INSULIN;

DOUBLE STRANDED RNA; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

BIOLOGY; SIGNALING;

AGED; AGING; ANIMAL EXPERIMENT; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DIAPAUSE; EMBRYO; LIFESPAN; LONGEVITY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; QUALITY OF LIFE; REPRODUCTION;

AGING; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; DEAD-BOX RNA HELICASES; INSULIN; INSULIN-LIKE GROWTH FACTOR I; LIFE CYCLE STAGES; LONGEVITY; MUTATION; OXIDATIVE STRESS; RECEPTOR, INSULIN; REPRODUCTION; RNA HELICASES; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TEMPERATURE; TRANSCRIPTION FACTORS;

ANIMALIA; CAENORHABDITIS; CAENORHABDITIS ELEGANS; INVERTEBRATA;

EID: 0037174629     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1074240     Document Type: Article

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26. We thank all members of the Kenyon lab for critical review and discussion of this work. A.D. was supported by the Cancer Research Fund of the Damon Runyon Foundation Fellowship, grant DRG-1525. D.K.C. was supported by a Howard Hughes Medical Institute Predoctoral Fellowship. Supported by a grant from the NIH (grant 5RO1AG11816) to C.K.