Ellagic acid prevents rat colon carcinogenesis induced by 1, 2 dimethyl hydrazine through inhibition of AKT-phosphoinositide-3 kinase pathway

European Journal of Pharmacology

Volumn 660, Issue 2-3, 2011, Pages 249-258

  Umesalma, Syed ^a   Sudhandiran, Ganapasam ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Apoptosis; Bcl 2; Caspase 3; Colon cancer; Dimethyl hydrazine; Ellagic acid; PI3K Akt signaling

Indexed keywords

1,2 DIMETHYLHYDRAZINE; CYTOCHROME C; ELLAGIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER PREVENTION; COLON CARCINOGENESIS; COLON CARCINOMA; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA FRAGMENTATION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

1,2-DIMETHYLHYDRAZINE; ANIMALS; APOPTOSIS; CARCINOGENS; CASPASE 3; COLONIC NEOPLASMS; CYTOCHROMES C; DNA FRAGMENTATION; ELLAGIC ACID; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, NEOPLASTIC; MALE; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN SUBUNITS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION;

EID: 79956116511     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.03.036     Document Type: Article

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