Clinicopathological significance of PTEN loss and the phosphoinositide 3-kinase/Akt pathway in sporadic colorectal neoplasms: is PTEN loss predictor of local recurrence?

American Journal of Surgery

Volumn 195, Issue 6, 2008, Pages 719-725

  Colakoglu, Tamer ^a   Yildirim, Sedat ^a   Kayaselcuk, Fazilet ^a   Nursal, Tarik Zafer ^a   Ezer, Ali ^a   Noyan, Turgut ^a   Karakayali, Hamdi ^a   Haberal, Mehmet ^a  

^a BASKENT UNIVERSITY   (Turkey)

Author keywords

Adenomatous polyp; Colon cancer; pAKT; PTEN expression

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ADENOMATOUS POLYP; ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CANCER PATIENT; CANCER RECURRENCE; CANCER SURVIVAL; COLON CARCINOGENESIS; COLORECTAL TUMOR; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE FREE SURVIVAL; FEMALE; GENE EXPRESSION; GENE LOSS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KAPLAN MEIER METHOD; MALE; MULTIVARIATE ANALYSIS; PHOSPHATASE AND TENSION HOMOLOGUE DELETED ON CHROMOSOME 10 GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEX DIFFERENCE; SIGNAL TRANSDUCTION; TISSUE SECTION; TUMOR LOCALIZATION; TUMOR SUPPRESSOR GENE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENOCARCINOMA; ADENOMATOUS POLYPS; ADULT; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; FEMALE; GENE EXPRESSION; GENES, TUMOR SUPPRESSOR; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION;

EID: 44349111717     PISSN: 00029610     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjsurg.2007.05.061     Document Type: Article

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