Targeted RNA interference of PI3K pathway components sensitizes colon cancer cells to TNF-related apoptosis-inducing ligand (TRAIL)

Surgery

Volumn 138, Issue 2, 2005, Pages 391-397

  Rychahou, Piotr G ^a   Murillo, Carlos A ^a   Evers, B Mark ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 3 INHIBITOR; CASPASE 8; DEATH RECEPTOR 4; DEATH RECEPTOR 5; DNA FRAGMENT; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN; PROTEIN 85ALPHA; PROTEIN BID; PROTEIN KINASE B; PROTEIN KINASE B1; PROTEIN P85; RNA; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; COLON CANCER; CONTROLLED STUDY; DRUG SENSITIVITY; DRUG TARGETING; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MEASUREMENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RIBONUCLEASE PROTECTION ASSAY; RNA INTERFERENCE; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; COLONIC NEOPLASMS; GENE THERAPY; HUMANS; MEMBRANE GLYCOPROTEINS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 24344482476     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.surg.2005.05.012     Document Type: Article

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