AKT-1, -2, and -3 are expressed in both normal and tumor tissues of the lung, breast, prostate, and colon

Clinical Cancer Research

Volumn 7, Issue 8, 2001, Pages 2475-2479

  Zinda, Michael J ^a   Johnson, Mac A ^a   Paul, Jonathan D ^a   Horn, Candice ^a   Konicek, Bruce W ^a   Lu, Zhao Hai ^a   Sandusky, George ^a   Thomas, James E ^a   Neubauer, Blake L ^a   Lai, Mei T ^a   Graff, Jeremy R ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN AKT 1; PROTEIN AKT 3; PROTEIN KINASE B; PROTEIN KINASE B BETA; UNCLASSIFIED DRUG;

ARTICLE; BREAST TUMOR; CARCINOGENESIS; CELL LINE; COLON TUMOR; CONTROLLED STUDY; DNA DETERMINATION; HUMAN; HUMAN CELL; LUNG TUMOR; PRIORITY JOURNAL; PROSTATE TUMOR; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR GROWTH;

BREAST; BREAST NEOPLASMS; COLON; COLONIC NEOPLASMS; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG; LUNG NEOPLASMS; MALE; NEOPLASMS; ONCOGENE PROTEINS; PROSTATE; PROSTATIC NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; TISSUE DISTRIBUTION; TUMOR CELLS, CULTURED;

EID: 0034881622     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

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4. Identification of a human Akt3 (protein kinase B γ) which contains the regulatory serine phosphorylation site
5. Isolation of DNA sequences amplified at chromosome 19q13.1-q13.2 including the AKT2 locus in human pancreatic cancer
6. Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas
7. AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas
8. Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines
9. Kip1 expression
10. Cell adhesion molecule uvomorulin expression in human breast cancer cell lines: Relationship to morphology and invasive capacities
11. A human protein kinase B γ with regulatory phosphorylation sites in the activation loop and in the C-terminal hydrophobic domain
12. Apoptosis in hormone-responsive malignancies