Potential role of lipid peroxidation derived DNA damage in human colon carcinogenesis: Studies on exocyclic base adducts as stable oxidative stress markers

Cancer Detection and Prevention

Volumn 26, Issue 4, 2002, Pages 308-312

  Bartsch, Helmut ^a   Nair, Jagadeesan ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Biomarkers; Colon cancer; Etheno DNA adducts; Oxidative damage

Indexed keywords

BIOLOGICAL MARKER;

ARTICLE; COLON TUMOR; DNA ADDUCT; DNA DAMAGE; DNA REPAIR; HUMAN; LIPID PEROXIDATION; OXIDATIVE STRESS;

BIOLOGICAL MARKERS; COLONIC NEOPLASMS; DNA ADDUCTS; DNA DAMAGE; DNA REPAIR; HUMANS; LIPID PEROXIDATION; OXIDATIVE STRESS;

EID: 0036996439     PISSN: 0361090X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-090X(02)00093-4     Document Type: Article

References (34)

1. Potter JD. Colorectal cancer: molecules and populations review. J Natl Cancer Inst 1999;91:916-32.
2. Stoler DL, Chen N, Basik M, et al. The onset and extent of genomic instability in sporadic colorectal tumor progression. Proc Natl Acad Sci USA 1999;96:15121-6.
3. Nair J, Gal A, Tamir S, et al. Etheno adducts in spleen DNA of SJL mice stimulated to overproduce nitric oxide. Carcinogenesis 1998;19:2081-4.
4. Nair J, Fürstenberger G, Bürger F, et al. Promutagenic etheno-DNA adducts in multistage mouse skin carcinogenesis: correlation with lipoxygenase-catalyzed arachidonic acid metabolism. Chem Res Toxicol 2000;13:703-9.
5. Ohshima H, Bartsch H. Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis. Mutat Res 1994;305:253-64.
6. Liu RH, Hotchkiss JH. Potential genotoxicity of chronically elevated nitric oxide: a review. Mutat Res 1995;339:73-89.
7. Ambs S, Bennett WP Merriam WG, et al. Relationship between p53 mutations and inducible nitric oxide synthase expression in human colorectal cancer. J Natl Cancer Inst 1999;91:86-8.
8. Tamir S, Burney S, Tannenbaum SR. DNA damage by nitric oxide. Chem Res Toxicol 1996;9:821-7.
9. Bartsch H, Nair J, Owen RW. Dietary polyunsaturated fatty acids and cancer of the breast and colorectum: emerging evidence for their role as risk modifiers. Carcinogenesis 1999;12:2209-18.
10. Chung F-L Chen H-JC, Nath RG. Lipid peroxidation as a potential endogenous source for the formation of exocyclic DNA adducts. Carcinogenesis 1996;17:2105-11.
11. Bartsch H. Exocyclic adducts as new risk markers for DNA damage in man. In: Singer B, Bartsch H, editors. Exocyclic DNA adducts in mutagenesis and carcinogenesis, IARC Scientific Publications No. 150. Lyons: IARC, 1999, pp. 1-16.
12. 32P-postlabelling in liver and lung DNA of mice treated with ethyl carbamate (urethane) or its metabolites. Carcinogenesis 1996;17:1711-8.
13. Bartsch H, Nair J. New DNA-based biomarkers for oxidative stress and cancer chemoprevention studies. Eur J Cancer 2000;36:1229-34.
14. 32P-postlabelling. Carcinogenesis 1995;16:613-7.
15. Nair J. Lipid peroxidation-induced etheno-DNA adducts in humans. In: Singer B, Bartsch H, editors. Exocyclic DNA adducts in mutagenesis and carcinogenesis, IARC Scientific Publications No. 150. Lyons: IARC, 1999, pp. 55-62.
16. Nair J, Barbin A, Velic I, Etheno H, et al. DNA-base adducts from endogenous reactive species. Mutat Res 1999;424:59-69.
17. Bartsch H, Barbin A, Marion MJ, et al. Formation, detection and role in carcinogenesis of ethenobases in DNA. Drug Metab Rev 1994;26:349-71.
18. Schmid K, Nair J, Winde G, et al. Increased levels of promutagenic etheno-DNA adducts in colonic polyps of FAP patients. Int J Cancer 2000;87:1-4.
19. 4-ethenocytosine by lipid peroxidation products and nucleic acid bases. Chem Res Toxicol 1995;8:278-83.
20. Eberhart CE, Coffey RJ, Radhika A, et al. Up-regulation of cyclooxygenase-2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 1994;107:1183-8.
21. Spigelman AD, Farmer KCR, Oliver S, et al. Caffeine phenotyping of cytochrome P4501A2, N-acetyltransferase, and xanthine oxidase in patients with familial adenomatous polyposis. Gut 1995;36:251-4.
22. Prescott SM, White RL. Self-promotion? Intimate connections between APC and prostaglandin H synthase-2. Cell 1996;87:783-6.
23. Fiocchi C. Inflammatory bowel disease: aetioology and pathogenesis. Gastroenterology 1998;115:182-205.
24. Nair J, Schmid K, Winde G, et al. Miscoding etheno-DNA adducts in colonic epithelium of patients suffering from Crohn's disease ulcerative colitis and familial adenomatous polyposis. Proc AACR 2000;41:594.
25. Andersen SN, Lovig T, Clausen OPF, et al. Villous, hypermucinous mucosa in long-standing ulcerative colitis shows high frequency of K-ras mutations. Gut 1999;45:686-92.
26. Hussain SP, Amstad P, Raja K, et al. Increased p53 mutation load in noncancerous colon tissue from ulcerative colitis: a cancer prone chromic inflammatory disease. Cancer Res 2000;60:3333-7.
27. 4-ethenocytosine are excised by separate human DNA glycosylases. Carcinogenesis 1996;17:155-7.
28. 6-ethenoadenine when present in DNA. Nucl Acids Res 1995;23:3750-5.
29. Wink DA, Vodovotz Y, Laval J, et al. The multifaceted roles of nitric oxide in cancer. Carcinogenesis 1998;19:711-21.
30. Jaiswal M, LaRusso NF, Burgart LJ, et al. Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism. Cancer Res 2000;60:184-90.
31. Owen RW, Mier W, Giacosa A, et al. Phenolic compounds and squalene in olive oils: the concentration and antioxidant potential of total phenols, simple phenols, secoiridoids, lignans and squalene. Food Chem Toxicol 2000;38:647-59.
32. Owen RW, Mier W, Giacosa A, et al. Phenolic and lipid components of olive oils: Identification of lignans as major components of the phenolic fraction of olive oil. Clin Chem 2000;46:976-88.
33. Owen RW, Giacosa A, Hull WE, et al. The antioxidant/anticancer potential of phenolic compounds isolated from olive oil. Eur J Cancer 2000;36:1235-47.
34. Owen RW, Giacosa A, Hull WE, et al. Olive oil consumption and health: the possible role of antioxidants. Lancet Oncol 2000;1:107-12.